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The map label for this gene is cobI [H]

Identifier: 83720325

GI number: 83720325

Start: 2729039

End: 2729773

Strand: Direct

Name: cobI [H]

Synonym: BTH_I2400

Alternate gene names: 83720325

Gene position: 2729039-2729773 (Clockwise)

Preceding gene: 83721244

Following gene: 83719162

Centisome position: 71.64

GC content: 68.71

Gene sequence:

>735_bases
ATGACGCGCAAGACTGGGCGCCTCTACGGGCTCGGCGTCGGGCCGGGCGACCCCGAACTGCTGACGATCAAGGCGCTGCG
TGTGCTGCAGGCCGCGCCCGTCGTCGCGTATTTCGTCGCGAAGGGCAAGAAAGGCAACGCGTTCAGCATCGTCGAGGGCC
ATCTGAGCGACGCGCAGACGCACCTGCCGCTCGTCTATCCGGTGACGACCGAGACGCTGCCGCCGCCCCTTTGCTACGAA
ACCGTGATCGCCGACTTCTACGACACGGCGGCCGCGCTCGTCGCAGCGCATCTCGACGCGGGCCGCGACGTCTCGGTGAT
CTGCGAAGGCGATCCGTTCTTCTACGGCTCGTACATGTACCTGCACGACCGGCTCGCGCCGCGCTACGACGCCGAGGTCG
TGCCGGGCGTGTGCTCGATGCTGGGCGGCGCGGCGGTGCTCGGCGTGCCGCTCGTCTACCGGAACCAGAGCCTCTCGGTG
CTCTCCGGCGTGCTGCCCGAGCACGAATTGCGCGAGCGGCTCGCGAAAGCCGACGCGGCCGTCGTGATGAAGCTCGGCCG
CAACTTCGACAAGGTGCGCCGCGTGCTCGACGAGCTCGGGCTCGCGCGCCGCGCGCTGTACGTCGAGCGCGCGACGATGG
CCGCGCAGCGGATCGTGCCGCTCGCGGAAGTCGATCCGATGGCGTCGCCGTATTTTTCGCTGCTCGTCGTGCCGGGGGAA
AAATGGCAAGGATGA

Upstream 100 bases:

>100_bases
CCGCCGACAGCCGCGGCGTGCCGTTCGTCGCGGTCGCGGGCCGCCGCGGCGGCAGCGCGATGGTCGCCGCCGCCGTCAAC
GCGCTCGCCTCGGAGGCCGA

Downstream 100 bases:

>100_bases
CCGCCGCGCCCGCGATCGTGATACTCGGGCCCGGCGCGCTCGATACCGCGCGCCGAATCCAGGCCCGCTACGACGGCGCT
CGGGTGCATGCGCTCGCGGG

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTRKTGRLYGLGVGPGDPELLTIKALRVLQAAPVVAYFVAKGKKGNAFSIVEGHLSDAQTHLPLVYPVTTETLPPPLCYE
TVIADFYDTAAALVAAHLDAGRDVSVICEGDPFFYGSYMYLHDRLAPRYDAEVVPGVCSMLGGAAVLGVPLVYRNQSLSV
LSGVLPEHELRERLAKADAAVVMKLGRNFDKVRRVLDELGLARRALYVERATMAAQRIVPLAEVDPMASPYFSLLVVPGE
KWQG

Sequences:

>Translated_244_residues
MTRKTGRLYGLGVGPGDPELLTIKALRVLQAAPVVAYFVAKGKKGNAFSIVEGHLSDAQTHLPLVYPVTTETLPPPLCYE
TVIADFYDTAAALVAAHLDAGRDVSVICEGDPFFYGSYMYLHDRLAPRYDAEVVPGVCSMLGGAAVLGVPLVYRNQSLSV
LSGVLPEHELRERLAKADAAVVMKLGRNFDKVRRVLDELGLARRALYVERATMAAQRIVPLAEVDPMASPYFSLLVVPGE
KWQG
>Mature_243_residues
TRKTGRLYGLGVGPGDPELLTIKALRVLQAAPVVAYFVAKGKKGNAFSIVEGHLSDAQTHLPLVYPVTTETLPPPLCYET
VIADFYDTAAALVAAHLDAGRDVSVICEGDPFFYGSYMYLHDRLAPRYDAEVVPGVCSMLGGAAVLGVPLVYRNQSLSVL
SGVLPEHELRERLAKADAAVVMKLGRNFDKVRRVLDELGLARRALYVERATMAAQRIVPLAEVDPMASPYFSLLVVPGEK
WQG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26469; Mature: 26338

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKTGRLYGLGVGPGDPELLTIKALRVLQAAPVVAYFVAKGKKGNAFSIVEGHLSDAQT
CCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
HLPLVYPVTTETLPPPLCYETVIADFYDTAAALVAAHLDAGRDVSVICEGDPFFYGSYMY
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCEE
LHDRLAPRYDAEVVPGVCSMLGGAAVLGVPLVYRNQSLSVLSGVLPEHELRERLAKADAA
EECCCCCCCCCHHHHHHHHHHCCHHHHHCCEEECCCCHHHHHHCCCHHHHHHHHHHHHHH
VVMKLGRNFDKVRRVLDELGLARRALYVERATMAAQRIVPLAEVDPMASPYFSLLVVPGE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCC
KWQG
CCCC
>Mature Secondary Structure 
TRKTGRLYGLGVGPGDPELLTIKALRVLQAAPVVAYFVAKGKKGNAFSIVEGHLSDAQT
CCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
HLPLVYPVTTETLPPPLCYETVIADFYDTAAALVAAHLDAGRDVSVICEGDPFFYGSYMY
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCEE
LHDRLAPRYDAEVVPGVCSMLGGAAVLGVPLVYRNQSLSVLSGVLPEHELRERLAKADAA
EECCCCCCCCCHHHHHHHHHHCCHHHHHCCEEECCCCHHHHHHCCCHHHHHHHHHHHHHH
VVMKLGRNFDKVRRVLDELGLARRALYVERATMAAQRIVPLAEVDPMASPYFSLLVVPGE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCC
KWQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]