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The map label for this gene is fhuB [H]

Identifier: 83720276

GI number: 83720276

Start: 2773492

End: 2775471

Strand: Reverse

Name: fhuB [H]

Synonym: BTH_I2423

Alternate gene names: 83720276

Gene position: 2775471-2773492 (Counterclockwise)

Preceding gene: 83721166

Following gene: 83719342

Centisome position: 72.86

GC content: 76.62

Gene sequence:

>1980_bases
ATGCGGCTCGCGCCCGAGTTGCACGTGTGGCTCGCCGCGCCGGCGGGCAGCGACGCCGCGCAGCTCGCGCACATCATGCT
GTTCGAGCTGGCCGCGCCGCGCGTCGCGGCGGCGCTCGTCGCGGGCGGCTGCCTCGCGATCGCGGGCGCGCTGTTCCAGT
CGCTCACGCGCAATCCGCTCGCGGCGCCGGATCTGCTCGGCATCACGGGCGGCGCGCAACTCGGCCTCATCGCCGCGATG
CTCGTGCCGGCGCTCGCCGGCCACGCGTCGGTGCCGCTGCTGTTCGCCTGCGGGCTCGCTGCGGCCGCGTGCGTGTCGGC
CGCGGCCGGCGGCTGGCGCGCGACGCCGCTGCGCCTCATTCTCGCGGGCAGCGTCTGCATGCTGCTGTTCTCGGCGGTCA
CGACGCTGTTGCTCGCGTTCTTCGAGGAGACGGTGGTCGGCGCATCGCTGTGGGCGAGCGGCAGCCTGTATCAGCCGGGC
GCGGCCGGGCTGCGCGACGCGCTGCTGTGGCTCGTCGCGCCGCTCGCCGCGCTGCCGCTCGTGATCCGGCCGCTCGATCC
GCTCGCGCTCGGCGACGACGCGGCGGCCGCGGCCGGCGTGCGCGTCGACGCGACGCGGCTCGCCGGCACCGTCGTCGCGG
TCGGCTTCGCGAGCGTCGCGGTCAGCATCGCGGGGCCGCTGTCGTACATCGGCCTGATCGCGCCCAACCTGATCCGGCAG
ATGCGCGGCGCGAAGGCGTCGAGGCTCGGCGCGCTCGTGCCGCTCGCCGCGCTCGCGGGCGGCGCGCTCGTGCTCGTCAC
CGACAGCGCGGTGCTCGCGCTCGGCCTCGATGCGACGCTGTCGACGGGCGTCGCGATCGCGTTCGTCGGCACGCCGCTGA
TGCTCGCGATGATTCGTCGCGGCGCGGCGTGGTCGGGCGCCGCGCAGCAGCCGGCGCAGGTGCAGGCGAACGCGCGCGGC
GGCGCGCGCGTCGTGCGCGCGATCGTCGCGCTGCCGTGGCCGGCCGTCGCGGCGCTGCTGCTGGCGGCGGGCGCCGCGGT
GTTCGTCGTCGGCGCGTCGTTCGGCACCGTGTGGATCGGCCCCGGACGCTGGCTCGCGGCGCTCGCGCAGCGCGACGACG
TCGCGCGGATGGTGCTCGATCTGCGCGCGCCGCGGCTCCTGTGCGCGTTGCTCGCGGGCGCGCTGCTCGGCGCGTCCGGC
GTGCTGATGCAGAGCATCGTGCGCAATCCGCTCGCGGGGCCCGAAGTACTCGGCGTCACGCAGGGCGCGGGGCTCGCGAC
GCTCGCCACGCTGGTTGCCTGGCCGCTCGCCGCGCACGGCACGCTCGTCGCCGCGTCGCTCGCGGGCGGCGGCGCGACGC
TTGCGCTCACGCTCGCGCTCAATCGCCGGCATCGCTATGCGCCGCTCGCCGTCGCGCTGACGGGCATCGTGATCGGCACG
CTGTGGACGACGCTCGCGCAGTGGCTGATCACGCAGGAGAGCGTGCAGCCCGCGCGCTTTGTCGTCTGGCTCGTCGGCGG
CACGTACGGGCGTAGCTGGGGCGAGGTCGTCGCGCTGCTGCCGTGGTGCGCGCTCGCGGTGCCGACGCTCGTGCTGCTCG
CGAAGCCGCTCGATCTGCTCGCGCTCGGCGACGAGCAGGCGGCCGCGCTCGGCTTGCCGATCGCCGTGCTGCGGCCGCTC
GTGCTGACGATCGCCACGCTCGCGGCTTGCGCGGCGGTCGCGGCGGTCGGCCCGGTCGGCTTCATCGGGCTGATGGCGCC
GCATCTCGCGGCGATGCTCGGCGCGCGCACGCACGCGACGCGTCTGTGGGTGGCCGCCGCGTGCGGCGCGCTGGTGCTCG
CCGCCGCCGATGTCGTCGCGCGCACGCTGCTCGCGCCGCGCGAGATTCCGGCGGGCGTGCTGACCGCGCTGATCGGCGCG
CCGTACCTGCTCGCGCTGCTGATCGCCGAAGCGCGGCGCGAGCGGCGGAGCGGGCGGTGA

Upstream 100 bases:

>100_bases
ATCCGCGCAGCAAACGCCGCCGGCATCGTGCTCGGCCACGCGCGGCCGTGTCGGCGCGATCGGCGGGGCGCTCGTCGCGC
TGATCGTCGTCACGGCCGCG

Downstream 100 bases:

>100_bases
GCGCGACGCGCTTTTCGACGTTCGCGCCTGCCGCGATCGAGCATTACCTCGAGCACGTGTGGCTCGGCGCGCCCGACGCG
CGCGACGAGCCCGCGCTTGC

Product: iron-hydroxamate transporter permease subunit

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Ferrichrome uptake protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MRLAPELHVWLAAPAGSDAAQLAHIMLFELAAPRVAAALVAGGCLAIAGALFQSLTRNPLAAPDLLGITGGAQLGLIAAM
LVPALAGHASVPLLFACGLAAAACVSAAAGGWRATPLRLILAGSVCMLLFSAVTTLLLAFFEETVVGASLWASGSLYQPG
AAGLRDALLWLVAPLAALPLVIRPLDPLALGDDAAAAAGVRVDATRLAGTVVAVGFASVAVSIAGPLSYIGLIAPNLIRQ
MRGAKASRLGALVPLAALAGGALVLVTDSAVLALGLDATLSTGVAIAFVGTPLMLAMIRRGAAWSGAAQQPAQVQANARG
GARVVRAIVALPWPAVAALLLAAGAAVFVVGASFGTVWIGPGRWLAALAQRDDVARMVLDLRAPRLLCALLAGALLGASG
VLMQSIVRNPLAGPEVLGVTQGAGLATLATLVAWPLAAHGTLVAASLAGGGATLALTLALNRRHRYAPLAVALTGIVIGT
LWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVVALLPWCALAVPTLVLLAKPLDLLALGDEQAAALGLPIAVLRPL
VLTIATLAACAAVAAVGPVGFIGLMAPHLAAMLGARTHATRLWVAAACGALVLAAADVVARTLLAPREIPAGVLTALIGA
PYLLALLIAEARRERRSGR

Sequences:

>Translated_659_residues
MRLAPELHVWLAAPAGSDAAQLAHIMLFELAAPRVAAALVAGGCLAIAGALFQSLTRNPLAAPDLLGITGGAQLGLIAAM
LVPALAGHASVPLLFACGLAAAACVSAAAGGWRATPLRLILAGSVCMLLFSAVTTLLLAFFEETVVGASLWASGSLYQPG
AAGLRDALLWLVAPLAALPLVIRPLDPLALGDDAAAAAGVRVDATRLAGTVVAVGFASVAVSIAGPLSYIGLIAPNLIRQ
MRGAKASRLGALVPLAALAGGALVLVTDSAVLALGLDATLSTGVAIAFVGTPLMLAMIRRGAAWSGAAQQPAQVQANARG
GARVVRAIVALPWPAVAALLLAAGAAVFVVGASFGTVWIGPGRWLAALAQRDDVARMVLDLRAPRLLCALLAGALLGASG
VLMQSIVRNPLAGPEVLGVTQGAGLATLATLVAWPLAAHGTLVAASLAGGGATLALTLALNRRHRYAPLAVALTGIVIGT
LWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVVALLPWCALAVPTLVLLAKPLDLLALGDEQAAALGLPIAVLRPL
VLTIATLAACAAVAAVGPVGFIGLMAPHLAAMLGARTHATRLWVAAACGALVLAAADVVARTLLAPREIPAGVLTALIGA
PYLLALLIAEARRERRSGR
>Mature_659_residues
MRLAPELHVWLAAPAGSDAAQLAHIMLFELAAPRVAAALVAGGCLAIAGALFQSLTRNPLAAPDLLGITGGAQLGLIAAM
LVPALAGHASVPLLFACGLAAAACVSAAAGGWRATPLRLILAGSVCMLLFSAVTTLLLAFFEETVVGASLWASGSLYQPG
AAGLRDALLWLVAPLAALPLVIRPLDPLALGDDAAAAAGVRVDATRLAGTVVAVGFASVAVSIAGPLSYIGLIAPNLIRQ
MRGAKASRLGALVPLAALAGGALVLVTDSAVLALGLDATLSTGVAIAFVGTPLMLAMIRRGAAWSGAAQQPAQVQANARG
GARVVRAIVALPWPAVAALLLAAGAAVFVVGASFGTVWIGPGRWLAALAQRDDVARMVLDLRAPRLLCALLAGALLGASG
VLMQSIVRNPLAGPEVLGVTQGAGLATLATLVAWPLAAHGTLVAASLAGGGATLALTLALNRRHRYAPLAVALTGIVIGT
LWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVVALLPWCALAVPTLVLLAKPLDLLALGDEQAAALGLPIAVLRPL
VLTIATLAACAAVAAVGPVGFIGLMAPHLAAMLGARTHATRLWVAAACGALVLAAADVVARTLLAPREIPAGVLTALIGA
PYLLALLIAEARRERRSGR

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786347, Length=657, Percent_Identity=31.9634703196347, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=38.9891696750903, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1788004, Length=307, Percent_Identity=35.5048859934853, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786804, Length=282, Percent_Identity=35.8156028368794, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790741, Length=270, Percent_Identity=36.6666666666667, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=33.1010452961672, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 66239; Mature: 66239

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAPELHVWLAAPAGSDAAQLAHIMLFELAAPRVAAALVAGGCLAIAGALFQSLTRNPL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAPDLLGITGGAQLGLIAAMLVPALAGHASVPLLFACGLAAAACVSAAAGGWRATPLRLI
CCCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LAGSVCMLLFSAVTTLLLAFFEETVVGASLWASGSLYQPGAAGLRDALLWLVAPLAALPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VIRPLDPLALGDDAAAAAGVRVDATRLAGTVVAVGFASVAVSIAGPLSYIGLIAPNLIRQ
HHCCCCCCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRGAKASRLGALVPLAALAGGALVLVTDSAVLALGLDATLSTGVAIAFVGTPLMLAMIRR
HHCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCHHHHCCEEEEHHHHHHHHHHHHC
GAAWSGAAQQPAQVQANARGGARVVRAIVALPWPAVAALLLAAGAAVFVVGASFGTVWIG
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHEEEECCCCEEEEC
PGRWLAALAQRDDVARMVLDLRAPRLLCALLAGALLGASGVLMQSIVRNPLAGPEVLGVT
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEC
QGAGLATLATLVAWPLAAHGTLVAASLAGGGATLALTLALNRRHRYAPLAVALTGIVIGT
CCCHHHHHHHHHHHHHHHCCHHEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
LWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVVALLPWCALAVPTLVLLAKPLDLL
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHE
ALGDEQAAALGLPIAVLRPLVLTIATLAACAAVAAVGPVGFIGLMAPHLAAMLGARTHAT
EECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLWVAAACGALVLAAADVVARTLLAPREIPAGVLTALIGAPYLLALLIAEARRERRSGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLAPELHVWLAAPAGSDAAQLAHIMLFELAAPRVAAALVAGGCLAIAGALFQSLTRNPL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAPDLLGITGGAQLGLIAAMLVPALAGHASVPLLFACGLAAAACVSAAAGGWRATPLRLI
CCCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LAGSVCMLLFSAVTTLLLAFFEETVVGASLWASGSLYQPGAAGLRDALLWLVAPLAALPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VIRPLDPLALGDDAAAAAGVRVDATRLAGTVVAVGFASVAVSIAGPLSYIGLIAPNLIRQ
HHCCCCCCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRGAKASRLGALVPLAALAGGALVLVTDSAVLALGLDATLSTGVAIAFVGTPLMLAMIRR
HHCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCHHHHCCEEEEHHHHHHHHHHHHC
GAAWSGAAQQPAQVQANARGGARVVRAIVALPWPAVAALLLAAGAAVFVVGASFGTVWIG
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHEEEECCCCEEEEC
PGRWLAALAQRDDVARMVLDLRAPRLLCALLAGALLGASGVLMQSIVRNPLAGPEVLGVT
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEC
QGAGLATLATLVAWPLAAHGTLVAASLAGGGATLALTLALNRRHRYAPLAVALTGIVIGT
CCCHHHHHHHHHHHHHHHCCHHEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
LWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVVALLPWCALAVPTLVLLAKPLDLL
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHE
ALGDEQAAALGLPIAVLRPLVLTIATLAACAAVAAVGPVGFIGLMAPHLAAMLGARTHAT
EECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLWVAAACGALVLAAADVVARTLLAPREIPAGVLTALIGAPYLLALLIAEARRERRSGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258 [H]