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The map label for this gene is alr [H]

Identifier: 83720249

GI number: 83720249

Start: 2271724

End: 2272794

Strand: Direct

Name: alr [H]

Synonym: BTH_I2007

Alternate gene names: 83720249

Gene position: 2271724-2272794 (Clockwise)

Preceding gene: 83720749

Following gene: 83719278

Centisome position: 59.64

GC content: 70.12

Gene sequence:

>1071_bases
ATGCCGCGCCCGATTTCCGCCACGATCCACACCGCAGCCCTCGCGAACAATCTCACCGTCGTGCGCCGCCACGCCGCCCA
GTCGAAGGTCTGGGCGATCGTCAAGGCGAACGCGTACGGGCACGGTCTCGCACGGGTCTTCCCCGGGCTGCGCGGCACCG
ACGGCTTCGGCCTGCTCGACCTCGACGAGGCCGTGAAGCTGCGCGAGCTCGGCTGGGCCGGGCCGATCCTGCTGCTCGAA
GGCTTCTTCCGGTCGACCGACATCGACGTGATCGACCGCTACAGCCTGACGACCGCGGTGCACAACGACGAGCAGATGCG
CATGCTCGAGACCGCGCGGCTGTCGAAGCCCGTCAACATTCAACTGAAGATGAACAGCGGAATGAACCGGCTCGGCTACG
CGCCGGAGAAGTTCCGCGCCGCGTGGGAGCGTGCGCGCGCGTGCCCGGGCATCGGCCAGATCACGTTGATGACCCATTTT
TCGGACGCCGACGGCGAACGCGGCGTGGCCGAGCAGATGGCGACGTTCGAGCGCGGCGCGCAAGGCATTGCCGGCGCGCG
CAGCCTCGCGAACTCGGCCGCCGTGCTCTGGCACCCGTCGGCGCACTTCGATTGGGTGCGGCCCGGCATCATGCTGTACG
GCGCATCGCCGTCCGGGCATTCGGCGGACATCGCGGGCAAGGGCCTGCAGCCGACGATGACGCTCGCCTCCGAACTGATC
GCCGTGCAGACGCTCGCGAAGGGGCAGGCGGTGGGCTACGGCTCCGTGTTCGTCGCCGAGGATACGATGCGCATCGGCGT
CGTCGCGTGCGGCTACGCGGACGGTTATCCGCGGATCGCGCCCGAGGGCACGCCCGTCGTCGTCGACGGCGTGCGCACGC
GGATCGTCGGCCGCGTGTCGATGGACATGCTGACCGTCGATCTCACGCCCGTGCCGCAGGCCGGCGTCGGCGCGCGCGTC
GAGCTTTGGGGCGAGACGCTGCCGATCGACGACGTCGCCGCGCGCTGCATGACGGTCGGCTACGAGCTGATGTGCGCGGT
CGCGCCGCGCGTGCCGGTGCGTGCCGAGTAA

Upstream 100 bases:

>100_bases
TCGGACTAGCAAGATCCCCCGATCGTTCCGCGCGTATCGGCGTCGCGCCCAAAAGGCGCGATAAGCTGATGATTCGCAAG
CGTCTTTACTGAAATTTCCT

Downstream 100 bases:

>100_bases
GGGCGCGCGCATGGCGAAGCAGAAGACGGTTTTCGTCTGCACCGAGTGCGGCGGGCAGACGCCGAAGTGGCAGGGGCAAT
GCCCGTCGTGCCAAGCATGG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPRPISATIHTAALANNLTVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNIQLKMNSGMNRLGYAPEKFRAAWERARACPGIGQITLMTHF
SDADGERGVAEQMATFERGAQGIAGARSLANSAAVLWHPSAHFDWVRPGIMLYGASPSGHSADIAGKGLQPTMTLASELI
AVQTLAKGQAVGYGSVFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARV
ELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE

Sequences:

>Translated_356_residues
MPRPISATIHTAALANNLTVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNIQLKMNSGMNRLGYAPEKFRAAWERARACPGIGQITLMTHF
SDADGERGVAEQMATFERGAQGIAGARSLANSAAVLWHPSAHFDWVRPGIMLYGASPSGHSADIAGKGLQPTMTLASELI
AVQTLAKGQAVGYGSVFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARV
ELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
>Mature_355_residues
PRPISATIHTAALANNLTVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLEG
FFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNIQLKMNSGMNRLGYAPEKFRAAWERARACPGIGQITLMTHFS
DADGERGVAEQMATFERGAQGIAGARSLANSAAVLWHPSAHFDWVRPGIMLYGASPSGHSADIAGKGLQPTMTLASELIA
VQTLAKGQAVGYGSVFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARVE
LWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=58.9235127478753, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=45.1704545454545, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38161; Mature: 38030

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPISATIHTAALANNLTVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCCHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNI
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCEEEEEEECCCHHHHHHHHHHCCCCEEE
QLKMNSGMNRLGYAPEKFRAAWERARACPGIGQITLMTHFSDADGERGVAEQMATFERGA
EEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
QGIAGARSLANSAAVLWHPSAHFDWVRPGIMLYGASPSGHSADIAGKGLQPTMTLASELI
CCHHHHHHHCCCCEEEECCCCCCCEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
AVQTLAKGQAVGYGSVFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVS
HHHHHHCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHEEEEEE
MDMLTVDLTPVPQAGVGARVELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
PRPISATIHTAALANNLTVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNI
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCEEEEEEECCCHHHHHHHHHHCCCCEEE
QLKMNSGMNRLGYAPEKFRAAWERARACPGIGQITLMTHFSDADGERGVAEQMATFERGA
EEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
QGIAGARSLANSAAVLWHPSAHFDWVRPGIMLYGASPSGHSADIAGKGLQPTMTLASELI
CCHHHHHHHCCCCEEEECCCCCCCEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
AVQTLAKGQAVGYGSVFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVS
HHHHHHCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHEEEEEE
MDMLTVDLTPVPQAGVGARVELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA