Click here to switch to the map view.

The map label for this gene is cof [C]

Identifier: 83720242

GI number: 83720242

Start: 3637439

End: 3638314

Strand: Reverse

Name: cof [C]

Synonym: BTH_I3191

Alternate gene names: 83720242

Gene position: 3638314-3637439 (Counterclockwise)

Preceding gene: 83720734

Following gene: 83719804

Centisome position: 95.51

GC content: 64.84

Gene sequence:

>876_bases
ATGTCCGCGTCCTGCCGCGTCACCCGCATCCTCCGACGTCCGCCATGTACCGCCATGTATAAAGTCATCGCCACCGATCT
CGACGGAACCTTGCTCAACAGCGACCACCAGCTCGATCCTTATACGATCGACACCGTACGGCGGCTCGCGGAAAGCGGCG
TGCCATTCGTGATCGCGACCGGGCGCCACTACGCGGACGTCGCCGGCATTCGCGACGTGCTCGGCATCCGCCCTTACCTG
ATCACGTCGAACGGCGCGCGCGTGCACTCGCCGGACGACACGCGGATTCACGCGCAGGACGTGCCCGCCGACGCGGTGCG
GCAACTGGTGCGGCCCGAACTCGTCGGCGCGCACGGCCGCGTGATCGTCAATCTGTTCACGAACGACGGCTGGCTGATCG
ATCGCGCCGCGCCGCATCTGCTCGCATTCCATCAGGATTCCGGATTTCGCTACGACGTCATCGACATGCTGTCGCACGAC
GGCGCGGACATCGCGAAGGTGCTGTACATCGGCGAGCCCGAGGACCTGGCCGTCGTGTCCGCCAACCTCGAGCGCACGTT
CGGCGGCGCGCTGTACGTCACATATTCGCTGCCTGACTGCCTCGAGGTGATGACGGCGAACGTATCGAAGGGGCGTGCGC
TACGTGTCGTGCTCGAGCGGCTCGGCGTCGATCCCGCGCACTGCGTCGCGTTCGGCGACAACATGAACGATATCGATCTG
CTCGAGACGGCGGGACATCCGTTCATGATGCGCAATGCGAATCCCGATCTCGTCGTGCGCCTGCCGAAGGTGCCGCGGAT
CGGCAATAATTTCGAAGCGGGGGTTGCGCGACATCTGCGCACGCTGTTCGCGCTCGAGGATTCGATCGCGCACTGA

Upstream 100 bases:

>100_bases
CGCGGCTCGGGCTCACGGCGTCACGCTGAGCCCGATCGGGGCGATCGACGGGCGCGAGCGGGCATCCGCGAGCGGCATTC
TTCGTCCGACGATAGAATGA

Downstream 100 bases:

>100_bases
GCGCCGCGCCGATCGCGCTCGCGGCCAGCCGCATCCGCAATGAAAAACGGGCGCCGCGGCGCCCGTTTTCGCTTTCGCCC
CGTCGCCGTCGGCCGGCGCG

Product: Cof-like hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSASCRVTRILRRPPCTAMYKVIATDLDGTLLNSDHQLDPYTIDTVRRLAESGVPFVIATGRHYADVAGIRDVLGIRPYL
ITSNGARVHSPDDTRIHAQDVPADAVRQLVRPELVGAHGRVIVNLFTNDGWLIDRAAPHLLAFHQDSGFRYDVIDMLSHD
GADIAKVLYIGEPEDLAVVSANLERTFGGALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDL
LETAGHPFMMRNANPDLVVRLPKVPRIGNNFEAGVARHLRTLFALEDSIAH

Sequences:

>Translated_291_residues
MSASCRVTRILRRPPCTAMYKVIATDLDGTLLNSDHQLDPYTIDTVRRLAESGVPFVIATGRHYADVAGIRDVLGIRPYL
ITSNGARVHSPDDTRIHAQDVPADAVRQLVRPELVGAHGRVIVNLFTNDGWLIDRAAPHLLAFHQDSGFRYDVIDMLSHD
GADIAKVLYIGEPEDLAVVSANLERTFGGALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDL
LETAGHPFMMRNANPDLVVRLPKVPRIGNNFEAGVARHLRTLFALEDSIAH
>Mature_290_residues
SASCRVTRILRRPPCTAMYKVIATDLDGTLLNSDHQLDPYTIDTVRRLAESGVPFVIATGRHYADVAGIRDVLGIRPYLI
TSNGARVHSPDDTRIHAQDVPADAVRQLVRPELVGAHGRVIVNLFTNDGWLIDRAAPHLLAFHQDSGFRYDVIDMLSHDG
ADIAKVLYIGEPEDLAVVSANLERTFGGALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLL
ETAGHPFMMRNANPDLVVRLPKVPRIGNNFEAGVARHLRTLFALEDSIAH

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=268, Percent_Identity=38.4328358208955, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI87081741, Length=261, Percent_Identity=36.3984674329502, Blast_Score=174, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 31976; Mature: 31845

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASCRVTRILRRPPCTAMYKVIATDLDGTLLNSDHQLDPYTIDTVRRLAESGVPFVIAT
CCCCCHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEHHHHHHHHHCCCCEEEEC
GRHYADVAGIRDVLGIRPYLITSNGARVHSPDDTRIHAQDVPADAVRQLVRPELVGAHGR
CCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCE
VIVNLFTNDGWLIDRAAPHLLAFHQDSGFRYDVIDMLSHDGADIAKVLYIGEPEDLAVVS
EEEEEECCCCEEEECCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEEEEECCCCCEEEEE
ANLERTFGGALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDL
CCHHHCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHH
LETAGHPFMMRNANPDLVVRLPKVPRIGNNFEAGVARHLRTLFALEDSIAH
HHCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASCRVTRILRRPPCTAMYKVIATDLDGTLLNSDHQLDPYTIDTVRRLAESGVPFVIAT
CCCCHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEHHHHHHHHHCCCCEEEEC
GRHYADVAGIRDVLGIRPYLITSNGARVHSPDDTRIHAQDVPADAVRQLVRPELVGAHGR
CCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHHHHCHHHCCCCCE
VIVNLFTNDGWLIDRAAPHLLAFHQDSGFRYDVIDMLSHDGADIAKVLYIGEPEDLAVVS
EEEEEECCCCEEEECCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEEEEECCCCCEEEEE
ANLERTFGGALYVTYSLPDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDL
CCHHHCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHH
LETAGHPFMMRNANPDLVVRLPKVPRIGNNFEAGVARHLRTLFALEDSIAH
HHCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]