| Definition | Burkholderia thailandensis E264 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_007651 |
| Length | 3,809,201 |
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The map label for this gene is ppsB [H]
Identifier: 83720213
GI number: 83720213
Start: 2662872
End: 2667449
Strand: Reverse
Name: ppsB [H]
Synonym: BTH_I2363
Alternate gene names: 83720213
Gene position: 2667449-2662872 (Counterclockwise)
Preceding gene: 83718897
Following gene: 83719419
Centisome position: 70.03
GC content: 71.1
Gene sequence:
>4578_bases ATGAGCACTCCGCACGTTGCAATCATCGGCATGGGTTGCAGGTTTCCGGGCGCGAGCTCGCCCGAGCAGTTCTGGGACAA CCTGGTGCACGGCGTCGAGTCCGTCACGTTCTTCGGCCCCGTCACGCCGACCGACGCCGGGTACGAGGTTCATGCCGCGG GCATCCTCGACGATGTCGCCGGGTTCGACGCGGCGCTGTTCGGGCTCAGCGCGCGGGAAGCCGAACGGATGGACCCTCAG CATCGCGTATGGCTCGAATGCGCATGGGAGGCGGCCGAACGCGCCGGCTACGATCCGAGGCGGCTGCCGGGCCGCACCGG CATATTTGCCGGCGCCGGTTTCAACGAATACCTGATTCGCAATCTCGTGCCGTCGGCGCTGCACGACGATCTGTCGTTGC TGCTCTCCAACGAGCCGTCGTTCCTGCCGTCGCGGCTCGCCTATCTGCTGGGTTGCACCGGCCCGGCCGTCTCGGTGTCG AGCGCCTGTTCGACATCGCTCGTCGCCGTGCATCTGGCCGTTCAGGCGCTGCTCGCCGACGAATGCGACACGGCCATCGC CGGCGGGGTTCGGATCACCACGCCGCAACGCCGCCCCTACCGCCACGAGCCCGGCGGCATCGGCTCGCCGGACGGCCATT GCCGCGCATTCGACCGCGAGGCCAACGGCACCGTCGGCGGCAACGGCGCGGGTGCCGTGGTGCTGCGCCGTCTGGACGAC GCGCTGGCCGACGGCGACCCCGTCGCCGCGGTCATTCTCGGCAGCGCGGTCTCCAACGACGGCGCGCGCCGGGTCGGCTT CACCGCGCCCGGCGTCGACGGGCAACGTTGCGCGATTCGCGAAGCGCAAGTGCTGGCCGACGTGCCGCCCGATTCGATCG GCATGATCGAGGCGCACGGCACCGCGACGGCGCTGGGCGACCCGGTGGAATTCGAGGCGCTGGCCGCCGCGTTCCGGCAA GGTACGGCGCGGCAGGGCTTTTGCGCGCTGGGCTCGGTCAAGACGAACATCGGCCACCTCGACGCGGCCGCCGGCATCGC GGGGCTGATCAAGACGGTGCTCGCGCTGCAGCATCGCGTGATTCCGCCATCGCTGCATTTTCACGAGCCCAATCCGCGCA TCGACCTGGCGAACTCGCCGTTCTTCGTGAACGCCGCCGCACGCCCGTGGCCCGATGCCACGCGGCGTGCCGGCGTCAGC TCGTTCGGCATGGGCGGCACCAACGCGCACCTCGTGCTGGAGTCCGCCGCCGAGCCGCAGCCCGACGCGGCCGGCGGCGA CGCCGGCGGCCCGTGGCCGCTCTTGCTGTCGGCGCGTTCCGAGGCGGCTGTGCGGCGGCTCGCGCGGGATCTCGCGGATC ATCTCGAGCGCGAGCGGCCGCCGCTCGCGGATGTCGCATACACGCTCGCGATGTCGCGCGGCGCGTTCGAATGGCGGATC GCCTGCGAGTGCGCGTCGCTCGACGAGGCGATCGAAATCCTCAGAGGCGATCTCCCGGTGACGCGCGCCGCGGCCGGCGC GGCGGCCGTCGCCGCGCGCGGACGCCGGGTTGCGTTGCCGCCGACGCCGTTCGAACATCAGCGCTACTGGATCGATCCGC CGTCGCCGCTCGCGCGCGTGGCGGACCCCGGCGGCTGGCTGTATGCGCCGCGCTTGCGCCAAAGCGCACCGCTCGAACGC GCGCCGATCGACACTCGGCGGCACTGGCTGGTGCTGCTCGACGAGCATGGCGTGGGCGCGCGCGTCGCGACGAGGCTGCG TGAGGCAGGCGCGCAGGTGGCGGAAATCGCGTATGCCGACGAGATGGATGCGCAAGCGATCGATGCGGCCGCCGCCGCGG CCGCAGATCGTCCTTCCTCCGTCATCGCGCTGTGGGGCCTCGCCGCGGAACCCGCCCGCGACGACGATTCGATGCTGAAA CGGCATTACATCCGCCCGGCGCGGCTCTTGCGCGCGTGGGCGGACCGCACGGGCGCCGATGTGGACGTCACCTTCGTCGC CGACGGCGCGCTGGCCGCGCAGGCCGGTTTCGGCGCGCCGGCCGCGCCGGAAAAAGCGATGCTGCTCGGCCTCGCGCGCG CGCTGCCGGCCGAATATCCCGGCTGGCGCGCGCGGGTTGCGGATGTCGACGCCGCCGCGGCCGATCTCGTCGAATGCATC GTCGCCGAAGCGTGCGCGCGCTCGGCCGACGACGCGGCGATCCATCGGCACGGATCGCGCTGGGTCGAAACCTTGGAACC CATCGGGGCCGCGACGACGCAGGCGATGGCGATCCGTCGCGACGGCGTCTACCTCGTCACGGGCGGCAACAGCGGCATGG GGCGCGCGATCGGCCGACATCTGGTCGAGCGCGGCGCGCGCGTGGTCGCGTTGAGCCGGCGCGGCGGCCAATCGATCCCC GGGCTGACCGCGATCGCGGTCGACGTGAGCGACCTCGATGCGTTGCGCCGAGCAGTCGCGCAGATCCGCGCCGAGCATGG CCCCATCAACGGCGTCGTGCATAGCGCGGGGATGCCGCCGCATGCATTGCTGCGCACGGCGGCCGATACCGCGATGCGCG ATGTGCTGGCGGGAAAATTCCTTGGCGCGCGCAATCTGCGGCAGGTGCTATGCGCCGACTCCCTCGATTTCGTCGTGCTG TGCTCGTCGCTGCGCGCGCATGTGCCGGCCGCCGGCGCGAGCGACTATATGGCGGCCAACCTCGCGCTGGAAGCGCTGGG CGCTTCGTGGGCGGCCGACGGTACGCGCGTGCGTGCGATCGCATGGGACACATGGACCGAGATCGGCATGGCGACGGTGT CCGACGAACGCTTCGTGCCGGAAGATCTGCGCACGGCGGGCCTGAGCGCCGACGAGGGCGTCAGGGTGCTCGAGATGGCG TCGGCTTGCGAATCGCCGCGCATCGCCGTCAGCACGCGCAAGCTGGACCCGCTGAAGGCCCGCGCCCGCGAGGCGTTTTC GCTGGCGCGCGCGGCCGACGCGCATCAGCCGGCCGCCGGCTCGCGGCATCCGAGGCCGGTGCTCGCGGTGCCGTACGTAC CGGCGCGAACCGCGCTCGAAGCCCGGCTCGCGACGATCTGGTCCGACGTGCTCGGCTTCGAGCCGATCGGCGTCATCGAC GACTTTTTCGACCTCGGCGGCGATTCCGTCGCCACCTTGCAGATCGTCGCGCGCGCGAAGGAGCAGGGCATTCATCTCGA TACGCATTTGGCTTTCGGCGCGCACACGATCGAAGAGCTTGCCGCCGCCGGCGTCGAGCGGACGGCGCAGGCCGTGCCGC GAGAAACGCCGCTGCCGCTCTCGCCAACTCAGCAATGGCTGTTCAATTGCGGATCGGGCGACATCAACCGCTTCGTGCAA GGCGTGGTTCTCAGCGTGCCGGCCGAGATCGATGCGACGGCGCTCGGCACCGCCATCGACGCCGCGATTGCGCACCACGC GGCGCTGGCGGCGCGCTTTGAGCAAACGGAATCCGGCTGGAAGCAGGTGCTCGGCACGCCCGCGCCTGTCGTCGTCGCCG TTCATCAGCACTCGGGGCCGGCCGACGAGCAACTCGGTTTCGCCCAGGAGATCGGCGCGGCGTTGCAGTGCTCGCTCGAC ATCCGGACGTCGCCGCTGCTGCGCGCCGCGCTCGTATTGGGCACGGCCGGCTCGATGCTGGTCCTCGTCGTCCATCACTT GCTGATCGATGCATTCAGTTGGCGAAGGCTGCTGGGCGACCTCCACGGGCGCGTCGGCGCATCGGCGCTGGCGGCAGGTC AGCAACGGGCGGCGGCCGATGAGTCGTTTTTCCACTGGGCGATCGCGCTCGAACGCGTCGCCGCGGCAGGGGAGCTCGAC GACGATGCGGCGTTCTGGTCATCGCTCGATACGCCGCCGGATGCGTTTCCCGTCGCGCGGCGCGATGGTGTGCGCCGCGC CCTGAATTCGACGCTCCCGGTCGCGCAGACGCTTGCGCTGAGCGCCACCCGTCGCCCGCTCGAAGCGCTGCTCGCGGTTG CCGTCGCGCGTGCGATCCGTAGCGTGGGCGAATCGGATCGGGTGCCGGTCGACATCGAGTCCTTCGGGCGCGGCTGGTCG CGCGTGCCATGCGACGTTTCAAGCGCGATCGGCTGGTTCACCGCCATTCATCCGCTCGTCGTGGACACATCGGCGGACAT CGAGGCCGCCGCGACGCATGCCGCGGCGCTGTTGCCGGACGCCCGCCGTCGCGCCGTCGCCTACACGGTGCTGCGCCAGG CCGCGCCGGAGCGCCTGCCCAAAGCGTTGCGAAGCGACGCGCCGATATCGATAGCGTTCTTCCCCGCGGAATCCGCCGCG CCGGCGTGGCCCATCGCCGCAATCCTGTCAGCGCCGGAGCAAACGCCGGCGCCGCACGCGATCGCGCTCGCCGCGACGAT CGAGGACGGCGCGCTGCGCATCGTGTGGCATGGCCAGGACGAGCCATTCGCCGGGTTGACGCTCGACACCATCGCCGCAC GGGCCATGAACGAACTGCGGGCGCTGGCGACGGCGGGAACGGCCAGGATGAGCACCATCCTCGCGCAGTTGGACATGTCG GAGGCAACCAATGATTGA
Upstream 100 bases:
>100_bases GCGAAACCCGCCAAGCCACCGCCGACGAACCGGACGAGCGCGCGCTGCGCCGCCGCCGCCGGACCATGGAACGCCGTCAA AAGATCGAGAGGGAACACGA
Downstream 100 bases:
>100_bases ACGGGTCGCAGCATTTCGGGACGTCGAAGCAGCGCTCGCGGAACCGGAGGCGGCGCTGGCGGCGGGCGATTTCGCCGCGG TGGAGCGCTTGATGGCCGGG
Product: polyketide synthase
Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 1525; Mature: 1524
Protein sequence:
>1525_residues MSTPHVAIIGMGCRFPGASSPEQFWDNLVHGVESVTFFGPVTPTDAGYEVHAAGILDDVAGFDAALFGLSAREAERMDPQ HRVWLECAWEAAERAGYDPRRLPGRTGIFAGAGFNEYLIRNLVPSALHDDLSLLLSNEPSFLPSRLAYLLGCTGPAVSVS SACSTSLVAVHLAVQALLADECDTAIAGGVRITTPQRRPYRHEPGGIGSPDGHCRAFDREANGTVGGNGAGAVVLRRLDD ALADGDPVAAVILGSAVSNDGARRVGFTAPGVDGQRCAIREAQVLADVPPDSIGMIEAHGTATALGDPVEFEALAAAFRQ GTARQGFCALGSVKTNIGHLDAAAGIAGLIKTVLALQHRVIPPSLHFHEPNPRIDLANSPFFVNAAARPWPDATRRAGVS SFGMGGTNAHLVLESAAEPQPDAAGGDAGGPWPLLLSARSEAAVRRLARDLADHLERERPPLADVAYTLAMSRGAFEWRI ACECASLDEAIEILRGDLPVTRAAAGAAAVAARGRRVALPPTPFEHQRYWIDPPSPLARVADPGGWLYAPRLRQSAPLER APIDTRRHWLVLLDEHGVGARVATRLREAGAQVAEIAYADEMDAQAIDAAAAAAADRPSSVIALWGLAAEPARDDDSMLK RHYIRPARLLRAWADRTGADVDVTFVADGALAAQAGFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAAAADLVECI VAEACARSADDAAIHRHGSRWVETLEPIGAATTQAMAIRRDGVYLVTGGNSGMGRAIGRHLVERGARVVALSRRGGQSIP GLTAIAVDVSDLDALRRAVAQIRAEHGPINGVVHSAGMPPHALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVL CSSLRAHVPAAGASDYMAANLALEALGASWAADGTRVRAIAWDTWTEIGMATVSDERFVPEDLRTAGLSADEGVRVLEMA SACESPRIAVSTRKLDPLKARAREAFSLARAADAHQPAAGSRHPRPVLAVPYVPARTALEARLATIWSDVLGFEPIGVID DFFDLGGDSVATLQIVARAKEQGIHLDTHLAFGAHTIEELAAAGVERTAQAVPRETPLPLSPTQQWLFNCGSGDINRFVQ GVVLSVPAEIDATALGTAIDAAIAHHAALAARFEQTESGWKQVLGTPAPVVVAVHQHSGPADEQLGFAQEIGAALQCSLD IRTSPLLRAALVLGTAGSMLVLVVHHLLIDAFSWRRLLGDLHGRVGASALAAGQQRAAADESFFHWAIALERVAAAGELD DDAAFWSSLDTPPDAFPVARRDGVRRALNSTLPVAQTLALSATRRPLEALLAVAVARAIRSVGESDRVPVDIESFGRGWS RVPCDVSSAIGWFTAIHPLVVDTSADIEAAATHAAALLPDARRRAVAYTVLRQAAPERLPKALRSDAPISIAFFPAESAA PAWPIAAILSAPEQTPAPHAIALAATIEDGALRIVWHGQDEPFAGLTLDTIAARAMNELRALATAGTARMSTILAQLDMS EATND
Sequences:
>Translated_1525_residues MSTPHVAIIGMGCRFPGASSPEQFWDNLVHGVESVTFFGPVTPTDAGYEVHAAGILDDVAGFDAALFGLSAREAERMDPQ HRVWLECAWEAAERAGYDPRRLPGRTGIFAGAGFNEYLIRNLVPSALHDDLSLLLSNEPSFLPSRLAYLLGCTGPAVSVS SACSTSLVAVHLAVQALLADECDTAIAGGVRITTPQRRPYRHEPGGIGSPDGHCRAFDREANGTVGGNGAGAVVLRRLDD ALADGDPVAAVILGSAVSNDGARRVGFTAPGVDGQRCAIREAQVLADVPPDSIGMIEAHGTATALGDPVEFEALAAAFRQ GTARQGFCALGSVKTNIGHLDAAAGIAGLIKTVLALQHRVIPPSLHFHEPNPRIDLANSPFFVNAAARPWPDATRRAGVS SFGMGGTNAHLVLESAAEPQPDAAGGDAGGPWPLLLSARSEAAVRRLARDLADHLERERPPLADVAYTLAMSRGAFEWRI ACECASLDEAIEILRGDLPVTRAAAGAAAVAARGRRVALPPTPFEHQRYWIDPPSPLARVADPGGWLYAPRLRQSAPLER APIDTRRHWLVLLDEHGVGARVATRLREAGAQVAEIAYADEMDAQAIDAAAAAAADRPSSVIALWGLAAEPARDDDSMLK RHYIRPARLLRAWADRTGADVDVTFVADGALAAQAGFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAAAADLVECI VAEACARSADDAAIHRHGSRWVETLEPIGAATTQAMAIRRDGVYLVTGGNSGMGRAIGRHLVERGARVVALSRRGGQSIP GLTAIAVDVSDLDALRRAVAQIRAEHGPINGVVHSAGMPPHALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVL CSSLRAHVPAAGASDYMAANLALEALGASWAADGTRVRAIAWDTWTEIGMATVSDERFVPEDLRTAGLSADEGVRVLEMA SACESPRIAVSTRKLDPLKARAREAFSLARAADAHQPAAGSRHPRPVLAVPYVPARTALEARLATIWSDVLGFEPIGVID DFFDLGGDSVATLQIVARAKEQGIHLDTHLAFGAHTIEELAAAGVERTAQAVPRETPLPLSPTQQWLFNCGSGDINRFVQ GVVLSVPAEIDATALGTAIDAAIAHHAALAARFEQTESGWKQVLGTPAPVVVAVHQHSGPADEQLGFAQEIGAALQCSLD IRTSPLLRAALVLGTAGSMLVLVVHHLLIDAFSWRRLLGDLHGRVGASALAAGQQRAAADESFFHWAIALERVAAAGELD DDAAFWSSLDTPPDAFPVARRDGVRRALNSTLPVAQTLALSATRRPLEALLAVAVARAIRSVGESDRVPVDIESFGRGWS RVPCDVSSAIGWFTAIHPLVVDTSADIEAAATHAAALLPDARRRAVAYTVLRQAAPERLPKALRSDAPISIAFFPAESAA PAWPIAAILSAPEQTPAPHAIALAATIEDGALRIVWHGQDEPFAGLTLDTIAARAMNELRALATAGTARMSTILAQLDMS EATND >Mature_1524_residues STPHVAIIGMGCRFPGASSPEQFWDNLVHGVESVTFFGPVTPTDAGYEVHAAGILDDVAGFDAALFGLSAREAERMDPQH RVWLECAWEAAERAGYDPRRLPGRTGIFAGAGFNEYLIRNLVPSALHDDLSLLLSNEPSFLPSRLAYLLGCTGPAVSVSS ACSTSLVAVHLAVQALLADECDTAIAGGVRITTPQRRPYRHEPGGIGSPDGHCRAFDREANGTVGGNGAGAVVLRRLDDA LADGDPVAAVILGSAVSNDGARRVGFTAPGVDGQRCAIREAQVLADVPPDSIGMIEAHGTATALGDPVEFEALAAAFRQG TARQGFCALGSVKTNIGHLDAAAGIAGLIKTVLALQHRVIPPSLHFHEPNPRIDLANSPFFVNAAARPWPDATRRAGVSS FGMGGTNAHLVLESAAEPQPDAAGGDAGGPWPLLLSARSEAAVRRLARDLADHLERERPPLADVAYTLAMSRGAFEWRIA CECASLDEAIEILRGDLPVTRAAAGAAAVAARGRRVALPPTPFEHQRYWIDPPSPLARVADPGGWLYAPRLRQSAPLERA PIDTRRHWLVLLDEHGVGARVATRLREAGAQVAEIAYADEMDAQAIDAAAAAAADRPSSVIALWGLAAEPARDDDSMLKR HYIRPARLLRAWADRTGADVDVTFVADGALAAQAGFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAAAADLVECIV AEACARSADDAAIHRHGSRWVETLEPIGAATTQAMAIRRDGVYLVTGGNSGMGRAIGRHLVERGARVVALSRRGGQSIPG LTAIAVDVSDLDALRRAVAQIRAEHGPINGVVHSAGMPPHALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVLC SSLRAHVPAAGASDYMAANLALEALGASWAADGTRVRAIAWDTWTEIGMATVSDERFVPEDLRTAGLSADEGVRVLEMAS ACESPRIAVSTRKLDPLKARAREAFSLARAADAHQPAAGSRHPRPVLAVPYVPARTALEARLATIWSDVLGFEPIGVIDD FFDLGGDSVATLQIVARAKEQGIHLDTHLAFGAHTIEELAAAGVERTAQAVPRETPLPLSPTQQWLFNCGSGDINRFVQG VVLSVPAEIDATALGTAIDAAIAHHAALAARFEQTESGWKQVLGTPAPVVVAVHQHSGPADEQLGFAQEIGAALQCSLDI RTSPLLRAALVLGTAGSMLVLVVHHLLIDAFSWRRLLGDLHGRVGASALAAGQQRAAADESFFHWAIALERVAAAGELDD DAAFWSSLDTPPDAFPVARRDGVRRALNSTLPVAQTLALSATRRPLEALLAVAVARAIRSVGESDRVPVDIESFGRGWSR VPCDVSSAIGWFTAIHPLVVDTSADIEAAATHAAALLPDARRRAVAYTVLRQAAPERLPKALRSDAPISIAFFPAESAAP AWPIAAILSAPEQTPAPHAIALAATIEDGALRIVWHGQDEPFAGLTLDTIAARAMNELRALATAGTARMSTILAQLDMSE ATND
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: COG3321
COG function: function code Q; Polyketide synthase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 acyl carrier domain [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=454, Percent_Identity=34.1409691629956, Blast_Score=225, Evalue=3e-58, Organism=Homo sapiens, GI8923559, Length=429, Percent_Identity=26.1072261072261, Blast_Score=95, Evalue=7e-19, Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=36, Blast_Score=69, Evalue=3e-11, Organism=Escherichia coli, GI1787337, Length=436, Percent_Identity=26.3761467889908, Blast_Score=102, Evalue=3e-22, Organism=Escherichia coli, GI1788663, Length=265, Percent_Identity=29.811320754717, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17550940, Length=499, Percent_Identity=31.2625250501002, Blast_Score=218, Evalue=2e-56, Organism=Caenorhabditis elegans, GI212642053, Length=432, Percent_Identity=30.787037037037, Blast_Score=199, Evalue=1e-50, Organism=Caenorhabditis elegans, GI71983541, Length=294, Percent_Identity=29.2517006802721, Blast_Score=89, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71983535, Length=274, Percent_Identity=29.5620437956204, Blast_Score=88, Evalue=5e-17, Organism=Saccharomyces cerevisiae, GI6320904, Length=451, Percent_Identity=23.5033259423503, Blast_Score=87, Evalue=3e-17, Organism=Drosophila melanogaster, GI24581345, Length=456, Percent_Identity=32.8947368421053, Blast_Score=209, Evalue=1e-53, Organism=Drosophila melanogaster, GI19920632, Length=453, Percent_Identity=31.3465783664459, Blast_Score=196, Evalue=1e-49, Organism=Drosophila melanogaster, GI221330659, Length=453, Percent_Identity=31.3465783664459, Blast_Score=196, Evalue=1e-49, Organism=Drosophila melanogaster, GI24644341, Length=291, Percent_Identity=29.8969072164948, Blast_Score=86, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR013968 - InterPro: IPR020806 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 160486; Mature: 160355
Theoretical pI: Translated: 5.83; Mature: 5.83
Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00024 HEMOPEXIN ; PS00098 THIOLASE_1 ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTPHVAIIGMGCRFPGASSPEQFWDNLVHGVESVTFFGPVTPTDAGYEVHAAGILDDVA CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEECHHHHHHH GFDAALFGLSAREAERMDPQHRVWLECAWEAAERAGYDPRRLPGRTGIFAGAGFNEYLIR HHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCHHHHHHH NLVPSALHDDLSLLLSNEPSFLPSRLAYLLGCTGPAVSVSSACSTSLVAVHLAVQALLAD HHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH ECDTAIAGGVRITTPQRRPYRHEPGGIGSPDGHCRAFDREANGTVGGNGAGAVVLRRLDD HCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH ALADGDPVAAVILGSAVSNDGARRVGFTAPGVDGQRCAIREAQVLADVPPDSIGMIEAHG HHCCCCCEEEEEECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECC TATALGDPVEFEALAAAFRQGTARQGFCALGSVKTNIGHLDAAAGIAGLIKTVLALQHRV CHHCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHCC IPPSLHFHEPNPRIDLANSPFFVNAAARPWPDATRRAGVSSFGMGGTNAHLVLESAAEPQ CCCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCC PDAAGGDAGGPWPLLLSARSEAAVRRLARDLADHLERERPPLADVAYTLAMSRGAFEWRI CCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE ACECASLDEAIEILRGDLPVTRAAAGAAAVAARGRRVALPPTPFEHQRYWIDPPSPLARV EEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCHHHHH ADPGGWLYAPRLRQSAPLERAPIDTRRHWLVLLDEHGVGARVATRLREAGAQVAEIAYAD CCCCCEEECCCHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHC EMDAQAIDAAAAAAADRPSSVIALWGLAAEPARDDDSMLKRHYIRPARLLRAWADRTGAD CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC VDVTFVADGALAAQAGFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAAAADLVECI EEEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHH VAEACARSADDAAIHRHGSRWVETLEPIGAATTQAMAIRRDGVYLVTGGNSGMGRAIGRH HHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCEEEEECCCCCHHHHHHHH LVERGARVVALSRRGGQSIPGLTAIAVDVSDLDALRRAVAQIRAEHGPINGVVHSAGMPP HHHCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCH HALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVLCSSLRAHVPAAGASDYMAAN HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHH LALEALGASWAADGTRVRAIAWDTWTEIGMATVSDERFVPEDLRTAGLSADEGVRVLEMA HHHHHHCCCCCCCCCEEEEEEECCHHHHCCEEECCCCCCCHHHHHCCCCCCCCHHHHHHH SACESPRIAVSTRKLDPLKARAREAFSLARAADAHQPAAGSRHPRPVLAVPYVPARTALE HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHH ARLATIWSDVLGFEPIGVIDDFFDLGGDSVATLQIVARAKEQGIHLDTHLAFGAHTIEEL HHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH AAAGVERTAQAVPRETPLPLSPTQQWLFNCGSGDINRFVQGVVLSVPAEIDATALGTAID HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHH AAIAHHAALAARFEQTESGWKQVLGTPAPVVVAVHQHSGPADEQLGFAQEIGAALQCSLD HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCHHHHCCCCEEEEEC IRTSPLLRAALVLGTAGSMLVLVVHHLLIDAFSWRRLLGDLHGRVGASALAAGQQRAAAD CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC ESFFHWAIALERVAAAGELDDDAAFWSSLDTPPDAFPVARRDGVRRALNSTLPVAQTLAL HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH SATRRPLEALLAVAVARAIRSVGESDRVPVDIESFGRGWSRVPCDVSSAIGWFTAIHPLV HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHE VDTSADIEAAATHAAALLPDARRRAVAYTVLRQAAPERLPKALRSDAPISIAFFPAESAA EECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC PAWPIAAILSAPEQTPAPHAIALAATIEDGALRIVWHGQDEPFAGLTLDTIAARAMNELR CCCHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH ALATAGTARMSTILAQLDMSEATND HHHHCCHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure STPHVAIIGMGCRFPGASSPEQFWDNLVHGVESVTFFGPVTPTDAGYEVHAAGILDDVA CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEECHHHHHHH GFDAALFGLSAREAERMDPQHRVWLECAWEAAERAGYDPRRLPGRTGIFAGAGFNEYLIR HHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCHHHHHHH NLVPSALHDDLSLLLSNEPSFLPSRLAYLLGCTGPAVSVSSACSTSLVAVHLAVQALLAD HHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH ECDTAIAGGVRITTPQRRPYRHEPGGIGSPDGHCRAFDREANGTVGGNGAGAVVLRRLDD HCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH ALADGDPVAAVILGSAVSNDGARRVGFTAPGVDGQRCAIREAQVLADVPPDSIGMIEAHG HHCCCCCEEEEEECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECC TATALGDPVEFEALAAAFRQGTARQGFCALGSVKTNIGHLDAAAGIAGLIKTVLALQHRV CHHCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHCC IPPSLHFHEPNPRIDLANSPFFVNAAARPWPDATRRAGVSSFGMGGTNAHLVLESAAEPQ CCCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCC PDAAGGDAGGPWPLLLSARSEAAVRRLARDLADHLERERPPLADVAYTLAMSRGAFEWRI CCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE ACECASLDEAIEILRGDLPVTRAAAGAAAVAARGRRVALPPTPFEHQRYWIDPPSPLARV EEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCHHHHH ADPGGWLYAPRLRQSAPLERAPIDTRRHWLVLLDEHGVGARVATRLREAGAQVAEIAYAD CCCCCEEECCCHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHC EMDAQAIDAAAAAAADRPSSVIALWGLAAEPARDDDSMLKRHYIRPARLLRAWADRTGAD CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC VDVTFVADGALAAQAGFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAAAADLVECI EEEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHH VAEACARSADDAAIHRHGSRWVETLEPIGAATTQAMAIRRDGVYLVTGGNSGMGRAIGRH HHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCEEEEECCCCCHHHHHHHH LVERGARVVALSRRGGQSIPGLTAIAVDVSDLDALRRAVAQIRAEHGPINGVVHSAGMPP HHHCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCH HALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVLCSSLRAHVPAAGASDYMAAN HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHH LALEALGASWAADGTRVRAIAWDTWTEIGMATVSDERFVPEDLRTAGLSADEGVRVLEMA HHHHHHCCCCCCCCCEEEEEEECCHHHHCCEEECCCCCCCHHHHHCCCCCCCCHHHHHHH SACESPRIAVSTRKLDPLKARAREAFSLARAADAHQPAAGSRHPRPVLAVPYVPARTALE HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHH ARLATIWSDVLGFEPIGVIDDFFDLGGDSVATLQIVARAKEQGIHLDTHLAFGAHTIEEL HHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH AAAGVERTAQAVPRETPLPLSPTQQWLFNCGSGDINRFVQGVVLSVPAEIDATALGTAID HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHH AAIAHHAALAARFEQTESGWKQVLGTPAPVVVAVHQHSGPADEQLGFAQEIGAALQCSLD HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCHHHHCCCCEEEEEC IRTSPLLRAALVLGTAGSMLVLVVHHLLIDAFSWRRLLGDLHGRVGASALAAGQQRAAAD CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC ESFFHWAIALERVAAAGELDDDAAFWSSLDTPPDAFPVARRDGVRRALNSTLPVAQTLAL HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH SATRRPLEALLAVAVARAIRSVGESDRVPVDIESFGRGWSRVPCDVSSAIGWFTAIHPLV HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHE VDTSADIEAAATHAAALLPDARRRAVAYTVLRQAAPERLPKALRSDAPISIAFFPAESAA EECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC PAWPIAAILSAPEQTPAPHAIALAATIEDGALRIVWHGQDEPFAGLTLDTIAARAMNELR CCCHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH ALATAGTARMSTILAQLDMSEATND HHHHCCHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: None [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]
Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]