Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 83720204

GI number: 83720204

Start: 2228153

End: 2229247

Strand: Direct

Name: serC [H]

Synonym: BTH_I1966

Alternate gene names: 83720204

Gene position: 2228153-2229247 (Clockwise)

Preceding gene: 83720770

Following gene: 83718908

Centisome position: 58.49

GC content: 66.39

Gene sequence:

>1095_bases
ATGCATCGCAATCAACTGAATTTCTCGGGTGGCCCCGGCGCGCTGCCGGATTCCGTGCTCGAACAGGTCCGGCAGGCGGT
CGTGGAGCTGCCGGAAACCGGCTTGTCCGTGCTCGGCATGAGCCACCGCTCGAGCTGGTTCTCGAATCTGCTCGCGCAGG
TGGAGGCGGACCTGCGCAGCTTGCTGAGCATTCCAGACGATTACTGCGTCGTGTTCCTGCAGGGCGGCAGCAGCCTGCAG
TTCTCGATGATCCCGATGAACTTCTCGCTGCCGGGCGCCGCCGCGCCCGAGTATGTGACGACGGGCTACTGGAGCCGCAA
GGCGATCGGCGAGGCGTCGCGCGTCGCCGCGATGCGCGTGGTCTGGGACGGCGCGGCGGGCGGCTACCGGACGCTGCCGT
CGCTTGCCGAGCTCGATTGGGACGCGCGCGCGTCGTTTCGTCACTACGTGTCCAACGAAACCGTCGAAGGACTTCAGTTT
CCGGAAGCGGCGGAGCTGCCCGGCAGCCCGCTGATCGCGGACATGTCGTCGGACTTCATGTCGAGGCCGTTTCGCGTGAG
CGCATATGGAATGGTCTATGCGCATGCGCAGAAGAATCTCGGGCCGGCCGGCGTGACGGTCGCGATCATCCGGCGCGCGC
TGCTCGAGCGCGTTCCCGACACGCTGCCGCCGATGCTCGATTTCCGCACGCATGTCGAGCATCGTTCGAACTACAACACG
CCGCCCGTATTCGCGATCTACGTGATGGCGCTCGTGCTGCGCTGGATTCGGGACGAAATCGGCGGCGTGCGCGCGATGCG
CGACATCAATGCCCGCAAGGCCGCCGCGCTCTACGCGACGCTCGACGCGCTGAGCGAAGTGATCGACTGCCATGCGCAGT
GCGCGGCGCGCTCGACGATGAACGTCGCGTTCCGCTTCAGGCAGGCGCGGCTCGATACGCTTTTCAAGGAGAAAGCCGCC
GAGGCGGGCTTCTGCGGCCTGAGCGGCCATCGCTCGATCGGCGGCGTTCGCGCGTCGCTGTACAACGCTGTCTCGGAGCA
GGCGGTAAGCCGGCTGAGCGCGTTCCTGAAGGACTTCGCGATCCGCTACGCGTGA

Upstream 100 bases:

>100_bases
CTCAACGCCGCGTTCCGACGGGGGGCGATGCGCCCGTCGGCGGGCTATCTGCAGAAGTGATCCGTTTTCGGTCTTCACCT
TGCCTCGGGAGTGTCGTCAG

Downstream 100 bases:

>100_bases
TGCGCGGGCGGGGCGCCCGCGCGTCGTGGCACGCGGCGCTTCGACGACGTCGACTCAACCCGAAAGAAGGAGATTGACCA
TGCTTTCCATCATCGTGACG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MHRNQLNFSGGPGALPDSVLEQVRQAVVELPETGLSVLGMSHRSSWFSNLLAQVEADLRSLLSIPDDYCVVFLQGGSSLQ
FSMIPMNFSLPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAAGGYRTLPSLAELDWDARASFRHYVSNETVEGLQF
PEAAELPGSPLIADMSSDFMSRPFRVSAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVRAMRDINARKAAALYATLDALSEVIDCHAQCAARSTMNVAFRFRQARLDTLFKEKAA
EAGFCGLSGHRSIGGVRASLYNAVSEQAVSRLSAFLKDFAIRYA

Sequences:

>Translated_364_residues
MHRNQLNFSGGPGALPDSVLEQVRQAVVELPETGLSVLGMSHRSSWFSNLLAQVEADLRSLLSIPDDYCVVFLQGGSSLQ
FSMIPMNFSLPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAAGGYRTLPSLAELDWDARASFRHYVSNETVEGLQF
PEAAELPGSPLIADMSSDFMSRPFRVSAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVRAMRDINARKAAALYATLDALSEVIDCHAQCAARSTMNVAFRFRQARLDTLFKEKAA
EAGFCGLSGHRSIGGVRASLYNAVSEQAVSRLSAFLKDFAIRYA
>Mature_364_residues
MHRNQLNFSGGPGALPDSVLEQVRQAVVELPETGLSVLGMSHRSSWFSNLLAQVEADLRSLLSIPDDYCVVFLQGGSSLQ
FSMIPMNFSLPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAAGGYRTLPSLAELDWDARASFRHYVSNETVEGLQF
PEAAELPGSPLIADMSSDFMSRPFRVSAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVRAMRDINARKAAALYATLDALSEVIDCHAQCAARSTMNVAFRFRQARLDTLFKEKAA
EAGFCGLSGHRSIGGVRASLYNAVSEQAVSRLSAFLKDFAIRYA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=41.1602209944751, Blast_Score=288, Evalue=7e-78,
Organism=Homo sapiens, GI10863955, Length=358, Percent_Identity=37.9888268156425, Blast_Score=245, Evalue=5e-65,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=38.3977900552486, Blast_Score=250, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=36.6666666666667, Blast_Score=258, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=36.9509043927649, Blast_Score=228, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21356589, Length=362, Percent_Identity=41.1602209944751, Blast_Score=274, Evalue=6e-74,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39899; Mature: 39899

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRNQLNFSGGPGALPDSVLEQVRQAVVELPETGLSVLGMSHRSSWFSNLLAQVEADLRS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLSIPDDYCVVFLQGGSSLQFSMIPMNFSLPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHE
VWDGAAGGYRTLPSLAELDWDARASFRHYVSNETVEGLQFPEAAELPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEHHHHHHHH
SRPFRVSAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCEEEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVRAMRDINARKAAALYATLDALSEVIDCHAQCAARSTM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQARLDTLFKEKAAEAGFCGLSGHRSIGGVRASLYNAVSEQAVSRLSAFLKDFA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRYA
HHCC
>Mature Secondary Structure
MHRNQLNFSGGPGALPDSVLEQVRQAVVELPETGLSVLGMSHRSSWFSNLLAQVEADLRS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLSIPDDYCVVFLQGGSSLQFSMIPMNFSLPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHE
VWDGAAGGYRTLPSLAELDWDARASFRHYVSNETVEGLQFPEAAELPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEHHHHHHHH
SRPFRVSAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCEEEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVRAMRDINARKAAALYATLDALSEVIDCHAQCAARSTM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQARLDTLFKEKAAEAGFCGLSGHRSIGGVRASLYNAVSEQAVSRLSAFLKDFA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRYA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA