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The map label for this gene is srpA [H]

Identifier: 83720133

GI number: 83720133

Start: 76454

End: 77539

Strand: Direct

Name: srpA [H]

Synonym: BTH_I0072

Alternate gene names: 83720133

Gene position: 76454-77539 (Clockwise)

Preceding gene: 83719910

Following gene: 83720035

Centisome position: 2.01

GC content: 71.18

Gene sequence:

>1086_bases
ATGGAACACCCTTCAACACCACCGGGCGCCGGGCCGGCGCGCGGCCTCTGGCGATGGGCGCTGATCGGCGGCGCGGTGAC
GGCGGTCGCGGCGACGTTCGGCTACGTCGGCGGCTGGCTCGCGCCGCATCGGCTGACGCCGCAGCGGCTCGTTGACGCGT
TGCAGCGCAATAGCGGTCTGCATCCGGGCTACCGGCGCAATCACGCGAAAGGCGTGTGCGTGACGGGCTATTTCGAAGGC
AACGGCGCGGCGAGCGCGTATTCGACCGCGCCCTTTTTCGCGGCGGTGCGCACGCCGGTGGTCGGGCGCTTCGCGATGCC
GGGCGGCAATCCGTACGCGCCGGATAGCAGCGTGCCGATCCGCAGCCTCGCGCTGCGCCTGAGCGCGCCGGATGGCGAGC
AATGGCGCACGGGGATGAACAGCATGCCGGTGTTTCCGGTGGCGACGCCGCGCGCGTTCTACGAGCAGACGGTGGCGGGC
CGGCCCGACCCGAGGACGGGCAAGCCCGATCCGGCGAAGCTGAAGGCGTTCTTCGACGCGCATCCGGAGACGGCCGCGTT
TCGCGCATGGGCGAAGACGGCGAAGCCGAGCGCGAGCTACGTCACCGAGACGTATTACAGCCTGAACGCGTTCTATCTCG
TCGATGCGGCGGGAAGGCGGCAGGCGGTGCGCTGGCGCGTCGCGCCGGAGCGGACGGCCGAGGCGGGTGAAGTCGCGAAA
GCCGGAGACCCGAACGTGTTGCAAGAGGACCTGACGCGGCGCATCGGTTCGGGGCCGCAGCGCTGGCATTTGCTGCTCAC
GCTGGCGGAGCCGGGCGACCCCGTCGACGACGCGACGCGCGTGTGGCCCGCGAATCGCACGACGATCGACGCGGGCACGC
TGGTGCTCGATCGCGTGGAGGCGCAGGACAGCGGGCCGTGCCGCGACGTCAACTACGACCCGACGATCCTGCCCGACGGC
ATCCGCGTGTCGGGCGACCCGCTGCTCGCCGCGCGCTCGGCCGCGTATGCGGATTCGTATCTGCGGCGCACGAGCGAAGA
GGCCGGGATTCCCGGCGCGGCGCATCCGCTTTCGGAGAAACGATGA

Upstream 100 bases:

>100_bases
TTATTCCATGCGTTCGAAAATAAATTTCGATGGAATAAACCGGGCGGCGGGCCGTCATACGCGCGTTCGACACAGGACCT
GACGGTCGGGAGCGTACACG

Downstream 100 bases:

>100_bases
TGAAGACGACGTTCAATCCGCTCGCGCGGCTGCTGCATTGGGTGATGGCGGCGATGATCGTGTCGATGCTGTTTGTCGGC
GCGGGGATGGTGGCGACGGT

Product: catalase

Products: O2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MEHPSTPPGAGPARGLWRWALIGGAVTAVAATFGYVGGWLAPHRLTPQRLVDALQRNSGLHPGYRRNHAKGVCVTGYFEG
NGAASAYSTAPFFAAVRTPVVGRFAMPGGNPYAPDSSVPIRSLALRLSAPDGEQWRTGMNSMPVFPVATPRAFYEQTVAG
RPDPRTGKPDPAKLKAFFDAHPETAAFRAWAKTAKPSASYVTETYYSLNAFYLVDAAGRRQAVRWRVAPERTAEAGEVAK
AGDPNVLQEDLTRRIGSGPQRWHLLLTLAEPGDPVDDATRVWPANRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTILPDG
IRVSGDPLLAARSAAYADSYLRRTSEEAGIPGAAHPLSEKR

Sequences:

>Translated_361_residues
MEHPSTPPGAGPARGLWRWALIGGAVTAVAATFGYVGGWLAPHRLTPQRLVDALQRNSGLHPGYRRNHAKGVCVTGYFEG
NGAASAYSTAPFFAAVRTPVVGRFAMPGGNPYAPDSSVPIRSLALRLSAPDGEQWRTGMNSMPVFPVATPRAFYEQTVAG
RPDPRTGKPDPAKLKAFFDAHPETAAFRAWAKTAKPSASYVTETYYSLNAFYLVDAAGRRQAVRWRVAPERTAEAGEVAK
AGDPNVLQEDLTRRIGSGPQRWHLLLTLAEPGDPVDDATRVWPANRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTILPDG
IRVSGDPLLAARSAAYADSYLRRTSEEAGIPGAAHPLSEKR
>Mature_361_residues
MEHPSTPPGAGPARGLWRWALIGGAVTAVAATFGYVGGWLAPHRLTPQRLVDALQRNSGLHPGYRRNHAKGVCVTGYFEG
NGAASAYSTAPFFAAVRTPVVGRFAMPGGNPYAPDSSVPIRSLALRLSAPDGEQWRTGMNSMPVFPVATPRAFYEQTVAG
RPDPRTGKPDPAKLKAFFDAHPETAAFRAWAKTAKPSASYVTETYYSLNAFYLVDAAGRRQAVRWRVAPERTAEAGEVAK
AGDPNVLQEDLTRRIGSGPQRWHLLLTLAEPGDPVDDATRVWPANRTTIDAGTLVLDRVEAQDSGPCRDVNYDPTILPDG
IRVSGDPLLAARSAAYADSYLRRTSEEAGIPGAAHPLSEKR

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=294, Percent_Identity=26.530612244898, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI48994891, Length=322, Percent_Identity=23.9130434782609, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71998444, Length=299, Percent_Identity=26.4214046822742, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920968, Length=293, Percent_Identity=27.3037542662116, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17981717, Length=293, Percent_Identity=25.938566552901, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6

Molecular weight: Translated: 38823; Mature: 38823

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHPSTPPGAGPARGLWRWALIGGAVTAVAATFGYVGGWLAPHRLTPQRLVDALQRNSGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
HPGYRRNHAKGVCVTGYFEGNGAASAYSTAPFFAAVRTPVVGRFAMPGGNPYAPDSSVPI
CCCHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCH
RSLALRLSAPDGEQWRTGMNSMPVFPVATPRAFYEQTVAGRPDPRTGKPDPAKLKAFFDA
HHEEEEECCCCCHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
HPETAAFRAWAKTAKPSASYVTETYYSLNAFYLVDAAGRRQAVRWRVAPERTAEAGEVAK
CCCHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCHHCCCCCCCCC
AGDPNVLQEDLTRRIGSGPQRWHLLLTLAEPGDPVDDATRVWPANRTTIDAGTLVLDRVE
CCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHCCCCCCCEECCCCEEEEECC
AQDSGPCRDVNYDPTILPDGIRVSGDPLLAARSAAYADSYLRRTSEEAGIPGAAHPLSEK
CCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MEHPSTPPGAGPARGLWRWALIGGAVTAVAATFGYVGGWLAPHRLTPQRLVDALQRNSGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
HPGYRRNHAKGVCVTGYFEGNGAASAYSTAPFFAAVRTPVVGRFAMPGGNPYAPDSSVPI
CCCHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCH
RSLALRLSAPDGEQWRTGMNSMPVFPVATPRAFYEQTVAGRPDPRTGKPDPAKLKAFFDA
HHEEEEECCCCCHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
HPETAAFRAWAKTAKPSASYVTETYYSLNAFYLVDAAGRRQAVRWRVAPERTAEAGEVAK
CCCHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCHHCCCCCCCCC
AGDPNVLQEDLTRRIGSGPQRWHLLLTLAEPGDPVDDATRVWPANRTTIDAGTLVLDRVE
CCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHCCCCCCCEECCCCEEEEECC
AQDSGPCRDVNYDPTILPDGIRVSGDPLLAARSAAYADSYLRRTSEEAGIPGAAHPLSEK
CCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: H2O2

Specific reaction: 2 H2O2 = O2 + 2 H2O

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]