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The map label for this gene is xanP [H]

Identifier: 83720121

GI number: 83720121

Start: 1143966

End: 1145354

Strand: Reverse

Name: xanP [H]

Synonym: BTH_I1007

Alternate gene names: 83720121

Gene position: 1145354-1143966 (Counterclockwise)

Preceding gene: 83719989

Following gene: 83718699

Centisome position: 30.07

GC content: 68.68

Gene sequence:

>1389_bases
ATGCAACCCGCCCCCCTTGCCCCACCCGCTTCCCACGGCGCCGACCACGCCGAATCGGCCCACGATCTCGTCTACGGCCC
CGACGATCGCCCCGCGCCGACGGTCGCCTTCGTCGCCGCGCTGCAACATCTGCTCGCCATCCTCGTGCCGATCGTCACGC
CCGGCCTGCTGATCTGCCAGGCGCTCGGCGTGGCGAGCCGCGACACGACGCTGATCGTGTCGATGTCGCTCGTGATCTCC
GGCATCGCGACCTTCGTCCAGTGCAAGCGCTTCGGCCCGCTCGGCGCCGGCCTGCTGATCGTCCAGGGCACGAGCTTCAA
CTTCGTCGGCCCGCTCATCGCAGGCGGCAGCCTGATGGTCAAGCAAGGCACGCCCGTCGAAACCGTGATGGCCGCGATCT
TCGGCGTCGTCATCGCCGGCTCGTTCGTCGAGATGGCCGTGTCGCGCATCCTGCCCTTCGTCAAGCGCCTGATCACCCCG
CTCGTCACCGGCATCGTCGTGCTGCTGATCGGCCTCACGCTGATCAAGGTCGGCCTCGTCAGCATGGGCGGCGGCTACGG
CGCGATCGCCAAGGGCAGCTTCGGCAGCGCCGAAAACCTGACGCTGTCGGGGCTCGTGCTCGGCACCATCATCGTGCTCA
ACCGCGTGCCCGTCGTCTGGGTGCGCAGCACCGCGCTCGTCATCGCGCTCGCGATCGGCTATCTCGCGGCCGCCGCGATG
GGCCGCCTCGACTTCACCGGCGCGCGCGAAGCCGCGCTGTTCCAGATCCCGACGCCGCTGCACTTCGGCCTCGGCTTCTC
ATGGTCACTCTTCGTGCCGATGCTGATCATCTATCTCGTCACGTCGCTCGAGGCGATCGGCGACGTCACGGCCACGAGCA
AGATCTCGCGGCAGCCCGTCGAGGGGCCGCTGTGGATGCGCCGCATCAAGGGCGGCGTGCTCGTGAACGGCGCGAACTCG
CTGCTCGCCGGCGTCTTCAACACGTTCCCGAGCTCCGTCTTCGCGCAGAACAACGGCGTGATCCAGCTCACCGGCATCGC
GAGCCGCCATGTCGGCATCTGGATCGCGGGCATGCTCGTGCTGCTCGGCCTGTTTCCCGTCGTCGCGGGCGTCCTGCAAG
CGGTGCCCGAGCCCGTGCTGGGCGGCGCCGCGATGGTGATGTTCGGCGCGGTGGCCGCGTCCGGCATCAACATCCTCGCC
GGCATCCGGCTAGACCGCCGCGCGCTGCTGATCATCGCCGTCTCGCTCGCCCTCGGGCTCGGCGTGTCGCAGGTGCCGGA
GATTCTCGCGAACCTGCCGCACGCGCTCAAGAACGTGCTCGAATCGGGCGTCGCGACAGGCGGCATCTGCGCGCTCGTGA
TGAACTGGTTCCTGCCCGAGAAGAAATGA

Upstream 100 bases:

>100_bases
CGGCTCACGGGCAAACCGACCGCCGGACCGCCACCGTCTGCCGGCCGCCGTCACCGCTTCCGTTAAAATCCCGCCTTTCC
ACCGCACCGGCTCTTTCGCG

Downstream 100 bases:

>100_bases
CGCGCCGCGGCGCGACAACCGCTCGCGAAACGAGCCGACCGCCGCCTTGCGCGCGTATGCGCTCACGCCCGCAACCCGCG
CACGGCGCAGCGGGCGTATT

Product: xanthine/uracil permease family protein subfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQPAPLAPPASHGADHAESAHDLVYGPDDRPAPTVAFVAALQHLLAILVPIVTPGLLICQALGVASRDTTLIVSMSLVIS
GIATFVQCKRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVETVMAAIFGVVIAGSFVEMAVSRILPFVKRLITP
LVTGIVVLLIGLTLIKVGLVSMGGGYGAIAKGSFGSAENLTLSGLVLGTIIVLNRVPVVWVRSTALVIALAIGYLAAAAM
GRLDFTGAREAALFQIPTPLHFGLGFSWSLFVPMLIIYLVTSLEAIGDVTATSKISRQPVEGPLWMRRIKGGVLVNGANS
LLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGIWIAGMLVLLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILA
GIRLDRRALLIIAVSLALGLGVSQVPEILANLPHALKNVLESGVATGGICALVMNWFLPEKK

Sequences:

>Translated_462_residues
MQPAPLAPPASHGADHAESAHDLVYGPDDRPAPTVAFVAALQHLLAILVPIVTPGLLICQALGVASRDTTLIVSMSLVIS
GIATFVQCKRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVETVMAAIFGVVIAGSFVEMAVSRILPFVKRLITP
LVTGIVVLLIGLTLIKVGLVSMGGGYGAIAKGSFGSAENLTLSGLVLGTIIVLNRVPVVWVRSTALVIALAIGYLAAAAM
GRLDFTGAREAALFQIPTPLHFGLGFSWSLFVPMLIIYLVTSLEAIGDVTATSKISRQPVEGPLWMRRIKGGVLVNGANS
LLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGIWIAGMLVLLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILA
GIRLDRRALLIIAVSLALGLGVSQVPEILANLPHALKNVLESGVATGGICALVMNWFLPEKK
>Mature_462_residues
MQPAPLAPPASHGADHAESAHDLVYGPDDRPAPTVAFVAALQHLLAILVPIVTPGLLICQALGVASRDTTLIVSMSLVIS
GIATFVQCKRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVETVMAAIFGVVIAGSFVEMAVSRILPFVKRLITP
LVTGIVVLLIGLTLIKVGLVSMGGGYGAIAKGSFGSAENLTLSGLVLGTIIVLNRVPVVWVRSTALVIALAIGYLAAAAM
GRLDFTGAREAALFQIPTPLHFGLGFSWSLFVPMLIIYLVTSLEAIGDVTATSKISRQPVEGPLWMRRIKGGVLVNGANS
LLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGIWIAGMLVLLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILA
GIRLDRRALLIIAVSLALGLGVSQVPEILANLPHALKNVLESGVATGGICALVMNWFLPEKK

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=493, Percent_Identity=22.5152129817444, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40316845, Length=493, Percent_Identity=22.5152129817444, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI44680145, Length=474, Percent_Identity=23.2067510548523, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI44680143, Length=478, Percent_Identity=23.0125523012552, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790087, Length=442, Percent_Identity=55.2036199095023, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI87082178, Length=446, Percent_Identity=44.1704035874439, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI87082181, Length=454, Percent_Identity=29.5154185022026, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1788843, Length=203, Percent_Identity=28.0788177339901, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081818, Length=469, Percent_Identity=24.5202558635394, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=476, Percent_Identity=23.9495798319328, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47649; Mature: 47649

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00879 ODR_DC_2_2 ; PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPAPLAPPASHGADHAESAHDLVYGPDDRPAPTVAFVAALQHLLAILVPIVTPGLLICQ
CCCCCCCCCCCCCCCHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ALGVASRDTTLIVSMSLVISGIATFVQCKRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCEEE
KQGTPVETVMAAIFGVVIAGSFVEMAVSRILPFVKRLITPLVTGIVVLLIGLTLIKVGLV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMGGGYGAIAKGSFGSAENLTLSGLVLGTIIVLNRVPVVWVRSTALVIALAIGYLAAAAM
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHH
GRLDFTGAREAALFQIPTPLHFGLGFSWSLFVPMLIIYLVTSLEAIGDVTATSKISRQPV
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
EGPLWMRRIKGGVLVNGANSLLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGIWIAGMLV
CCHHHHHHHCCCEEEECHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
LLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGIRLDRRALLIIAVSLALGL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHC
GVSQVPEILANLPHALKNVLESGVATGGICALVMNWFLPEKK
CHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQPAPLAPPASHGADHAESAHDLVYGPDDRPAPTVAFVAALQHLLAILVPIVTPGLLICQ
CCCCCCCCCCCCCCCHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ALGVASRDTTLIVSMSLVISGIATFVQCKRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCEEE
KQGTPVETVMAAIFGVVIAGSFVEMAVSRILPFVKRLITPLVTGIVVLLIGLTLIKVGLV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMGGGYGAIAKGSFGSAENLTLSGLVLGTIIVLNRVPVVWVRSTALVIALAIGYLAAAAM
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHH
GRLDFTGAREAALFQIPTPLHFGLGFSWSLFVPMLIIYLVTSLEAIGDVTATSKISRQPV
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
EGPLWMRRIKGGVLVNGANSLLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGIWIAGMLV
CCHHHHHHHCCCEEEECHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
LLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGIRLDRRALLIIAVSLALGL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHC
GVSQVPEILANLPHALKNVLESGVATGGICALVMNWFLPEKK
CHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]