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The map label for this gene is rcsC [H]

Identifier: 83720083

GI number: 83720083

Start: 3053876

End: 3055831

Strand: Reverse

Name: rcsC [H]

Synonym: BTH_I2675

Alternate gene names: 83720083

Gene position: 3055831-3053876 (Counterclockwise)

Preceding gene: 83721014

Following gene: 83719569

Centisome position: 80.22

GC content: 71.93

Gene sequence:

>1956_bases
ATGCTGGCCGCGACCGGGCCCTGCAAGTGGACGCATGTGTACCCATTGCTGTGGGGCAGCCACGTGCTCGTCGCGCTGTT
GAGCTACGGATGGGCGCACCGCGATCTGAAGCGGCTGCAGGCGGCGCTCAGAGCGAGCCGGGGCTCGCTCGCGACCGCGA
GCCACGAGTTGCGCGCGCCCGTGAACGGCATGCTCGCGCTCGTCGAGCTGGTGAGGCAGGGGCTGCTCGCGCCGGAGCAG
CAGCGGCTGCTGAGTCTCGTGCAGGACTCGGGGCAGTCGCTCGCGCGCGTGCTGAACGACATTCTCGATCACGCGAGCAT
CGAGGCGGGGCAATTCGCGATCGAGAAGACGCGCGTCGACGTGCGCGAGCTCGTCGACAGCGTGAGCGCGATGCTCGCGG
TGCAAGCGCATCGCAAGGGGTTGCGGGTCCGGCTGCACGTCGACGCCAACGTGCCGGCCGCGGTGCTGACGGACGGCAAT
CGACTGCGGCAGATTCTCGTCAACCTGATCGGCAACGGCATCAAGTACACGGAGCGCGGCAGCGTGTCGGTGCGCGTGCG
CGCGACGGACGCCGTCGACGGCTCGGTCGAGATCGTCGCGACGGTCGTCGACACGGGAATCGGCATTGCCGCCGACGAGT
TGAGGCGGCTTTTCACGCCGTTCGTGCGCGCGGCGCGCGGCGCACGGCGCACGGAATCGGGAACGGGGCTCGGGCTTGCG
ATCGCGCGCAAGCTCGCGCGATTGCTGGGAGGCGACGTGACGTTGACGAGTGATGAAGGCAGGGGGACGACGGCGACCGC
GCGCATTCGCTGCGCGGTCGCTGCGCGCGGCTATGCGCCCGATGCGCTTGCGGGGCGGGTCGTATCGATCGACGTCGCCG
ATGGCGCGCTCGCGGCGACGCTTGCCGCCTATGCGCGCGCGGCCGGCTTGCGGGTGGCCGCGCGCGGCGCGGCGCACGTC
GATGCGGTGCTGTGTGACGACGCGCGCGTCGACGCTTCGCGGCCGCAGGTCGGCTGGGTCGGCGTGACCGACGCGCCTCA
GCCTGGCGGCTGGACCGGCGACGGCGCGCACGTGCGCCTGAGCAGCAATCCGCTCGGCTGGCGCGCGTTCGCAGACAGCC
TGCGCGCCGCGCTCGACGCGCGCGACGCAGCGGGCGCGCGCATGGCGGCGGAGGGCAAGTCGCGCGCCTATCGCGTGCTG
GTCGTCGACGATCAGGAGATGAACCGCATCGTGCTGCGCTATCAGCTCGATGCGCTCGGCCACCGCGCGCGCCTTGTCGC
GAGCGGCGACGAAGCGTTGCGCGCGCTCGTGCGGAGCGCATTCGACGTCGTGCTGACCGACTGCCGGATGCCGGGCATGG
ACGGCGTCGCGCTGACGGCGGCGATCCGCGCGCATCCGGATGCGCGCGTGCGCGCGACGCCCATTGTCGGCGTGACGGCG
CTCGTGTCGGACGCCGAACACGCGCGCTGCGTCGCGGCCGGCATGACGTCCTGCATCGGCAAGCCGACGACGCTCGACGC
GCTCGAGCGCGCGCTCATCGATGCGATCGAGCCCGCGCCCGCGTTGCGCTTCGATCCGTCTCGCATCGACGCGGCGCGCA
TGCTCGCGGGATTCGGCGCGCCGTCCGCGCGCGGCGCGGCGCGCGACGCGATCCTGCTCGCGTGCCGCCGCGCGCTCGAG
CGCGACCGGGACACGCTCACGCGCCATCTGCGCGACGGCCTGTCCGAGCGCGAACTGCGTGCGTGGTGCCACACGGCGCG
CGGCACGTACAGCCTGTTCGGGCAGACGCACGTCGATGCGATGCTCGACGAATTCCACCATCTGCTGACGGCGGGCGACG
CGCGCGCGATTCGCGGCGCGGTCCGGGAAACATTCGCGATGGTGAACCATCTGCTGCGCTGCGTTGCGCATCCGGCGCAA
TCGCGCGATCGCGGCGATCCAAAAGGAGGAAGGTAA

Upstream 100 bases:

>100_bases
TTGCGGAGGCAAATTCTGTCGACGCATACTGGTGTGCATCTCCGCTGCGGCGCTCGCGTTCCTGACGCTGTCGCAGGTCA
CCAATCGGATGCAGGAGGGC

Downstream 100 bases:

>100_bases
ATGAGCGTTCAAGTGTTGATCGCGGACGACCATCCGCTCGTGCTGTTGGGGGTGCGCCACATGCTGGCGGGCGTGGGCGA
CGTGTCGATCGTCGGCGAGG

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MLAATGPCKWTHVYPLLWGSHVLVALLSYGWAHRDLKRLQAALRASRGSLATASHELRAPVNGMLALVELVRQGLLAPEQ
QRLLSLVQDSGQSLARVLNDILDHASIEAGQFAIEKTRVDVRELVDSVSAMLAVQAHRKGLRVRLHVDANVPAAVLTDGN
RLRQILVNLIGNGIKYTERGSVSVRVRATDAVDGSVEIVATVVDTGIGIAADELRRLFTPFVRAARGARRTESGTGLGLA
IARKLARLLGGDVTLTSDEGRGTTATARIRCAVAARGYAPDALAGRVVSIDVADGALAATLAAYARAAGLRVAARGAAHV
DAVLCDDARVDASRPQVGWVGVTDAPQPGGWTGDGAHVRLSSNPLGWRAFADSLRAALDARDAAGARMAAEGKSRAYRVL
VVDDQEMNRIVLRYQLDALGHRARLVASGDEALRALVRSAFDVVLTDCRMPGMDGVALTAAIRAHPDARVRATPIVGVTA
LVSDAEHARCVAAGMTSCIGKPTTLDALERALIDAIEPAPALRFDPSRIDAARMLAGFGAPSARGAARDAILLACRRALE
RDRDTLTRHLRDGLSERELRAWCHTARGTYSLFGQTHVDAMLDEFHHLLTAGDARAIRGAVRETFAMVNHLLRCVAHPAQ
SRDRGDPKGGR

Sequences:

>Translated_651_residues
MLAATGPCKWTHVYPLLWGSHVLVALLSYGWAHRDLKRLQAALRASRGSLATASHELRAPVNGMLALVELVRQGLLAPEQ
QRLLSLVQDSGQSLARVLNDILDHASIEAGQFAIEKTRVDVRELVDSVSAMLAVQAHRKGLRVRLHVDANVPAAVLTDGN
RLRQILVNLIGNGIKYTERGSVSVRVRATDAVDGSVEIVATVVDTGIGIAADELRRLFTPFVRAARGARRTESGTGLGLA
IARKLARLLGGDVTLTSDEGRGTTATARIRCAVAARGYAPDALAGRVVSIDVADGALAATLAAYARAAGLRVAARGAAHV
DAVLCDDARVDASRPQVGWVGVTDAPQPGGWTGDGAHVRLSSNPLGWRAFADSLRAALDARDAAGARMAAEGKSRAYRVL
VVDDQEMNRIVLRYQLDALGHRARLVASGDEALRALVRSAFDVVLTDCRMPGMDGVALTAAIRAHPDARVRATPIVGVTA
LVSDAEHARCVAAGMTSCIGKPTTLDALERALIDAIEPAPALRFDPSRIDAARMLAGFGAPSARGAARDAILLACRRALE
RDRDTLTRHLRDGLSERELRAWCHTARGTYSLFGQTHVDAMLDEFHHLLTAGDARAIRGAVRETFAMVNHLLRCVAHPAQ
SRDRGDPKGGR
>Mature_651_residues
MLAATGPCKWTHVYPLLWGSHVLVALLSYGWAHRDLKRLQAALRASRGSLATASHELRAPVNGMLALVELVRQGLLAPEQ
QRLLSLVQDSGQSLARVLNDILDHASIEAGQFAIEKTRVDVRELVDSVSAMLAVQAHRKGLRVRLHVDANVPAAVLTDGN
RLRQILVNLIGNGIKYTERGSVSVRVRATDAVDGSVEIVATVVDTGIGIAADELRRLFTPFVRAARGARRTESGTGLGLA
IARKLARLLGGDVTLTSDEGRGTTATARIRCAVAARGYAPDALAGRVVSIDVADGALAATLAAYARAAGLRVAARGAAHV
DAVLCDDARVDASRPQVGWVGVTDAPQPGGWTGDGAHVRLSSNPLGWRAFADSLRAALDARDAAGARMAAEGKSRAYRVL
VVDDQEMNRIVLRYQLDALGHRARLVASGDEALRALVRSAFDVVLTDCRMPGMDGVALTAAIRAHPDARVRATPIVGVTA
LVSDAEHARCVAAGMTSCIGKPTTLDALERALIDAIEPAPALRFDPSRIDAARMLAGFGAPSARGAARDAILLACRRALE
RDRDTLTRHLRDGLSERELRAWCHTARGTYSLFGQTHVDAMLDEFHHLLTAGDARAIRGAVRETFAMVNHLLRCVAHPAQ
SRDRGDPKGGR

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=487, Percent_Identity=32.6488706365503, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI1789149, Length=506, Percent_Identity=29.6442687747036, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=38.6100386100386, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=30.7692307692308, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI87082128, Length=214, Percent_Identity=29.9065420560748, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=25.4166666666667, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=27.9475982532751, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=212, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69359; Mature: 69359

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAATGPCKWTHVYPLLWGSHVLVALLSYGWAHRDLKRLQAALRASRGSLATASHELRAP
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCHHHHCC
VNGMLALVELVRQGLLAPEQQRLLSLVQDSGQSLARVLNDILDHASIEAGQFAIEKTRVD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VRELVDSVSAMLAVQAHRKGLRVRLHVDANVPAAVLTDGNRLRQILVNLIGNGIKYTERG
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCEEECCC
SVSVRVRATDAVDGSVEIVATVVDTGIGIAADELRRLFTPFVRAARGARRTESGTGLGLA
CEEEEEEECCCCCCCHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IARKLARLLGGDVTLTSDEGRGTTATARIRCAVAARGYAPDALAGRVVSIDVADGALAAT
HHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEECCCCCHHHCCCEEEEEECCCHHHHH
LAAYARAAGLRVAARGAAHVDAVLCDDARVDASRPQVGWVGVTDAPQPGGWTGDGAHVRL
HHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEE
SSNPLGWRAFADSLRAALDARDAAGARMAAEGKSRAYRVLVVDDQEMNRIVLRYQLDALG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCCCEEEEEEHHHCC
HRARLVASGDEALRALVRSAFDVVLTDCRMPGMDGVALTAAIRAHPDARVRATPIVGVTA
CCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHH
LVSDAEHARCVAAGMTSCIGKPTTLDALERALIDAIEPAPALRFDPSRIDAARMLAGFGA
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
PSARGAARDAILLACRRALERDRDTLTRHLRDGLSERELRAWCHTARGTYSLFGQTHVDA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCHHHHHH
MLDEFHHLLTAGDARAIRGAVRETFAMVNHLLRCVAHPAQSRDRGDPKGGR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLAATGPCKWTHVYPLLWGSHVLVALLSYGWAHRDLKRLQAALRASRGSLATASHELRAP
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCHHHHCC
VNGMLALVELVRQGLLAPEQQRLLSLVQDSGQSLARVLNDILDHASIEAGQFAIEKTRVD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VRELVDSVSAMLAVQAHRKGLRVRLHVDANVPAAVLTDGNRLRQILVNLIGNGIKYTERG
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCEEECCC
SVSVRVRATDAVDGSVEIVATVVDTGIGIAADELRRLFTPFVRAARGARRTESGTGLGLA
CEEEEEEECCCCCCCHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IARKLARLLGGDVTLTSDEGRGTTATARIRCAVAARGYAPDALAGRVVSIDVADGALAAT
HHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEECCCCCHHHCCCEEEEEECCCHHHHH
LAAYARAAGLRVAARGAAHVDAVLCDDARVDASRPQVGWVGVTDAPQPGGWTGDGAHVRL
HHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEE
SSNPLGWRAFADSLRAALDARDAAGARMAAEGKSRAYRVLVVDDQEMNRIVLRYQLDALG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCCCEEEEEEHHHCC
HRARLVASGDEALRALVRSAFDVVLTDCRMPGMDGVALTAAIRAHPDARVRATPIVGVTA
CCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHH
LVSDAEHARCVAAGMTSCIGKPTTLDALERALIDAIEPAPALRFDPSRIDAARMLAGFGA
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
PSARGAARDAILLACRRALERDRDTLTRHLRDGLSERELRAWCHTARGTYSLFGQTHVDA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCHHHHHH
MLDEFHHLLTAGDARAIRGAVRETFAMVNHLLRCVAHPAQSRDRGDPKGGR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]