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The map label for this gene is moeA [H]

Identifier: 83719995

GI number: 83719995

Start: 2476026

End: 2477708

Strand: Direct

Name: moeA [H]

Synonym: BTH_I2200

Alternate gene names: 83719995

Gene position: 2476026-2477708 (Clockwise)

Preceding gene: 83718524

Following gene: 83720736

Centisome position: 65.0

GC content: 72.25

Gene sequence:

>1683_bases
ATGTCGGCGAGGGAGCGGCCTGACCGGACAGCCCGATCGGCGGCATGCGCCGATCGGGCTGCGTTCCTTTCGGACGATCG
GCCACGCACATACGGTCCGGCGTGCGGTTCGGACGGAACTCGATTGCGGTGCGCTTGGCCGATCGTGCCGGCAATCGCGC
GGCCGAAATCCGGCGACATGCCGTTTTCGTCCATCGAACGCGGCCGCCTTGCGCCGCCGTTCGCCGTTCGCCGTGATCCG
TCGCGCTCGTCGCGCTCGTCGCGCTCGGCGCGCCACGCGAGACCGGATCGTTGCGATCGGTCGCCCACACCCGCGCGGCG
GCGTCGCTACAATGTCGCCATCCGGTCAACATTTCAATCGACGATGTCCCACCCCAACCCCCAGACGCCGCGCGCGCCGA
TGCTGTCGACGGCCGATGCGCTGGCGGCGCTTCTCGCGGCGGCGCGCCCGCTCGCCGAGATCGAAACCGTGCCGACGCTC
GAGGCGCTCAACCGCGTGCTTGCGGCCGATGTCGTGTCGCCGCTCGACGTGCCGCCGATGAACACGAGCGCGATGGACGG
CTACGCGGTGCGCATCGCCGACCTGACGCGCGGCGAGCGGCGCCTGCCGGTGTCGCAGCGCATTCCCGCGGGCCATCCGG
CCAGGCCGCTCGCGCCGGGCACGGCCGCGCGCATCTTCACGGGCGCGTCCGTGCCGGCCGGCGCGGACGCGGTCGTGATG
CAGGAGCAGACGGAGGCGGCGGGCGACCAGGTCGACATCCTGCACACGCCGACGGCGGGCGAATGGATCACCGCGCAGGG
CGCGGACATCCGCCGCGGCTCGGTGATCCTGCCGGCCGGCACGCGGATGACGCCGCAGGCGATCGGGCTTGCCGCGTCGG
TCGGCTGCGCGTCGCTCGCGGTCACGCGGCGCGTGAAGGTCGCGGTGTTCTTCACGGGCGACGAACTGACGATGCCGGGC
GAGCCGCTCAAGCCCGGCGCGATCTACAACTCGAACCGCTTCACGCTGCGCGGGCTGCTCGAGCGGCTCGGCTGCGACGT
GACCGACTACGGCATCGTGCCGGATAGGCTCGACGCGACGCGTGCGGCGCTGCGCGAGGCGGCGCGCGCGCACGACGTGA
TCGTGACGTGCGGTGGCGTGTCGGTGGGTGACGAGGATCATGTGAAGCCCGCGGTCGAGGCGGAAGGCCGGCTCGCGCTG
TGGCAGATCGCGATGAAGCCGGGCAAGCCGCTCGCGTTCGGCGCGATCCGGCGCGGCGGCGCGGCGGGCGGGACGGCTGG
GGGCGAAGCGAGCGCGGACGATGCGGCCGGCGCGAGTGACGCGAGCGCGGCGCCGGGCGGCGAAGCGTATTTCATCGGCT
TGCCGGGCAACCCGGTGTCGAGCTTCGTCACGTTCCTGCTGTTCGTGCGGCCGTTCCTGCTGCGCGTCGCGGGCGCGACG
CAGGTCGCGCCGCGCGCGGTGTCGCTGCGCGCGGACTTCACGCAGAGCAAGGCCGACCGCCGCAACGAATTCCTGCGCGC
GCGCGTGAACGCGGCGGGCGGACTCGACCTGTTCCCGAACCAGAGCTCGGCCGTGCTGACCTCGACGGTATGGAGCGACG
GCCTGATCGACAATCCGCCGAACCACGCGATCAGCGCGGGCGAGACGGTGCGTTTCATCCCTTTTTCCGAATTGCTCGGC
TGA

Upstream 100 bases:

>100_bases
CGCCGCATGGCCGTCGCGCGAACCCGGCCGAGGGGCCAGGCCCGCGGCACGGGCGGCGCGGCATATTCGTCAGGCTCATT
CCGGGCTGATCCGTGCCGCC

Downstream 100 bases:

>100_bases
AGCCGGGCGGTGTAATGACGATGAAGATCGAACTGAAGTTTTTTGCGAGCGTGCGCGAAGCGCTCGGCGTCGCGAGCGAG
ACGGTGACGGTGCCGGACGG

Product: molybdopterin biosynthesis moeA protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSARERPDRTARSAACADRAAFLSDDRPRTYGPACGSDGTRLRCAWPIVPAIARPKSGDMPFSSIERGRLAPPFAVRRDP
SRSSRSSRSARHARPDRCDRSPTPARRRRYNVAIRSTFQSTMSHPNPQTPRAPMLSTADALAALLAAARPLAEIETVPTL
EALNRVLAADVVSPLDVPPMNTSAMDGYAVRIADLTRGERRLPVSQRIPAGHPARPLAPGTAARIFTGASVPAGADAVVM
QEQTEAAGDQVDILHTPTAGEWITAQGADIRRGSVILPAGTRMTPQAIGLAASVGCASLAVTRRVKVAVFFTGDELTMPG
EPLKPGAIYNSNRFTLRGLLERLGCDVTDYGIVPDRLDATRAALREAARAHDVIVTCGGVSVGDEDHVKPAVEAEGRLAL
WQIAMKPGKPLAFGAIRRGGAAGGTAGGEASADDAAGASDASAAPGGEAYFIGLPGNPVSSFVTFLLFVRPFLLRVAGAT
QVAPRAVSLRADFTQSKADRRNEFLRARVNAAGGLDLFPNQSSAVLTSTVWSDGLIDNPPNHAISAGETVRFIPFSELLG

Sequences:

>Translated_560_residues
MSARERPDRTARSAACADRAAFLSDDRPRTYGPACGSDGTRLRCAWPIVPAIARPKSGDMPFSSIERGRLAPPFAVRRDP
SRSSRSSRSARHARPDRCDRSPTPARRRRYNVAIRSTFQSTMSHPNPQTPRAPMLSTADALAALLAAARPLAEIETVPTL
EALNRVLAADVVSPLDVPPMNTSAMDGYAVRIADLTRGERRLPVSQRIPAGHPARPLAPGTAARIFTGASVPAGADAVVM
QEQTEAAGDQVDILHTPTAGEWITAQGADIRRGSVILPAGTRMTPQAIGLAASVGCASLAVTRRVKVAVFFTGDELTMPG
EPLKPGAIYNSNRFTLRGLLERLGCDVTDYGIVPDRLDATRAALREAARAHDVIVTCGGVSVGDEDHVKPAVEAEGRLAL
WQIAMKPGKPLAFGAIRRGGAAGGTAGGEASADDAAGASDASAAPGGEAYFIGLPGNPVSSFVTFLLFVRPFLLRVAGAT
QVAPRAVSLRADFTQSKADRRNEFLRARVNAAGGLDLFPNQSSAVLTSTVWSDGLIDNPPNHAISAGETVRFIPFSELLG
>Mature_559_residues
SARERPDRTARSAACADRAAFLSDDRPRTYGPACGSDGTRLRCAWPIVPAIARPKSGDMPFSSIERGRLAPPFAVRRDPS
RSSRSSRSARHARPDRCDRSPTPARRRRYNVAIRSTFQSTMSHPNPQTPRAPMLSTADALAALLAAARPLAEIETVPTLE
ALNRVLAADVVSPLDVPPMNTSAMDGYAVRIADLTRGERRLPVSQRIPAGHPARPLAPGTAARIFTGASVPAGADAVVMQ
EQTEAAGDQVDILHTPTAGEWITAQGADIRRGSVILPAGTRMTPQAIGLAASVGCASLAVTRRVKVAVFFTGDELTMPGE
PLKPGAIYNSNRFTLRGLLERLGCDVTDYGIVPDRLDATRAALREAARAHDVIVTCGGVSVGDEDHVKPAVEAEGRLALW
QIAMKPGKPLAFGAIRRGGAAGGTAGGEASADDAAGASDASAAPGGEAYFIGLPGNPVSSFVTFLLFVRPFLLRVAGATQ
VAPRAVSLRADFTQSKADRRNEFLRARVNAAGGLDLFPNQSSAVLTSTVWSDGLIDNPPNHAISAGETVRFIPFSELLG

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=425, Percent_Identity=33.1764705882353, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI10880983, Length=425, Percent_Identity=33.1764705882353, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI1787049, Length=348, Percent_Identity=43.3908045977011, Blast_Score=273, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI25147659, Length=365, Percent_Identity=30.6849315068493, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17562606, Length=221, Percent_Identity=27.1493212669683, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17136978, Length=425, Percent_Identity=32, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638841, Length=425, Percent_Identity=32, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 59018; Mature: 58887

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARERPDRTARSAACADRAAFLSDDRPRTYGPACGSDGTRLRCAWPIVPAIARPKSGDM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCC
PFSSIERGRLAPPFAVRRDPSRSSRSSRSARHARPDRCDRSPTPARRRRYNVAIRSTFQS
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TMSHPNPQTPRAPMLSTADALAALLAAARPLAEIETVPTLEALNRVLAADVVSPLDVPPM
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NTSAMDGYAVRIADLTRGERRLPVSQRIPAGHPARPLAPGTAARIFTGASVPAGADAVVM
CCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCHHEEEECCCCCCCCCEEEE
QEQTEAAGDQVDILHTPTAGEWITAQGADIRRGSVILPAGTRMTPQAIGLAASVGCASLA
ECHHHHCCCEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
VTRRVKVAVFFTGDELTMPGEPLKPGAIYNSNRFTLRGLLERLGCDVTDYGIVPDRLDAT
HEEEEEEEEEEECCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
RAALREAARAHDVIVTCGGVSVGDEDHVKPAVEAEGRLALWQIAMKPGKPLAFGAIRRGG
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHCCC
AAGGTAGGEASADDAAGASDASAAPGGEAYFIGLPGNPVSSFVTFLLFVRPFLLRVAGAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
QVAPRAVSLRADFTQSKADRRNEFLRARVNAAGGLDLFPNQSSAVLTSTVWSDGLIDNPP
HHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEHHHCCCCCCCCC
NHAISAGETVRFIPFSELLG
CCCCCCCCEEEEECHHHHCC
>Mature Secondary Structure 
SARERPDRTARSAACADRAAFLSDDRPRTYGPACGSDGTRLRCAWPIVPAIARPKSGDM
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCC
PFSSIERGRLAPPFAVRRDPSRSSRSSRSARHARPDRCDRSPTPARRRRYNVAIRSTFQS
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TMSHPNPQTPRAPMLSTADALAALLAAARPLAEIETVPTLEALNRVLAADVVSPLDVPPM
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NTSAMDGYAVRIADLTRGERRLPVSQRIPAGHPARPLAPGTAARIFTGASVPAGADAVVM
CCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCHHEEEECCCCCCCCCEEEE
QEQTEAAGDQVDILHTPTAGEWITAQGADIRRGSVILPAGTRMTPQAIGLAASVGCASLA
ECHHHHCCCEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
VTRRVKVAVFFTGDELTMPGEPLKPGAIYNSNRFTLRGLLERLGCDVTDYGIVPDRLDAT
HEEEEEEEEEEECCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
RAALREAARAHDVIVTCGGVSVGDEDHVKPAVEAEGRLALWQIAMKPGKPLAFGAIRRGG
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHCCC
AAGGTAGGEASADDAAGASDASAAPGGEAYFIGLPGNPVSSFVTFLLFVRPFLLRVAGAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
QVAPRAVSLRADFTQSKADRRNEFLRARVNAAGGLDLFPNQSSAVLTSTVWSDGLIDNPP
HHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEHHHCCCCCCCCC
NHAISAGETVRFIPFSELLG
CCCCCCCCEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]