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The map label for this gene is dhaT [H]

Identifier: 83719904

GI number: 83719904

Start: 3026692

End: 3027840

Strand: Reverse

Name: dhaT [H]

Synonym: BTH_I2655

Alternate gene names: 83719904

Gene position: 3027840-3026692 (Counterclockwise)

Preceding gene: 83718677

Following gene: 83721514

Centisome position: 79.49

GC content: 71.71

Gene sequence:

>1149_bases
GTGGCCTATATCTATTACCTGACGCACATCCATCTCGGCGACGACGCGCTCGCGATGCTCGGCGCCGAGTGCGCGCGCAG
CGGCATCGCGCGGCCGCTCGTCGTGACGGACAAGGGCGTCGCGGCCGCGGGGCTCGTCGATCGCGCGCTCGATGCGCTCG
GCCTCGGCGCGCTGCCCGTGTTCGACGACACGCCGTCGAATCCGACCGAAGCCGCCGTGCTCGCCGCCGCGCAGCGCTAT
CGCGACGAAGGCTGCGACGGGCTCGTCGCGGTCGGCGGCGGCTCGGCGATCGATCTCGCGAAGGGCGTCGCGATCGCGGC
GACGCATCCCGCGCCGCTCACGCAATACGCGACGATCGAGGGCGGCAGCGGCCGGATCAGCGCGGGCGTCGCGCCGCTCA
TCGCGGTGCCGACGACGTCGGGCACGGGCAGCGAGGTCGCGCGCGGCGCGATCCTGATCCTCGCCGACGGCCGCAAGCTC
GGCTTCCATTCGTGGCATCTGCTGCCGAAGGCGGCGATCTGCGATCCGTCGCTCACGCTCGGCCTGCCGCCCGGGCTCAC
GGCGGCGACCGGCATGGACGCGATCGCGCACTGCATCGAAACGTTTCTCGCGCCGGCGTTCAATCCACCCGCCGACGGCA
TCGCGCTCGACGGCCTCGAGCGCGCGTGGGCGCACATCGAGCGCGCGACGCACGACGGCGGCGACCGCGCCGCGCGCCTC
GCGATGATGAGCGCGTCGATGCAGGGCGCGATGGCGTTCCAGAAAGGGCTCGGCTGCGTGCATTCGCTGTCGCATCCGTT
GGGCGGCGTGAAGGTGAACGGCAAGACGTCGCTGCATCACGGCACGCTGAACGCGGTCGTGCTGCCCGCAGTGCTGCGCT
TCAACGAGCACGCGCCGAGCGTCGTCGCCGAGCGCCGCTATGCGCGGATGCGCCGCGTGATGAACCTGCCGGAGAACGCG
GACCTGCCGCAGGCGCTGCACGACATGACGGCGCGCCTCGGCCTGCCGACGGGCCTCGCGCAAATGGGCGTCGACGAGCG
TGTGTTCGACCACGTGATCGAAGGCGCGCTCGCCGACCATTGCCACAAGACGAATCCGCGCGTCGCGTCGGCCGACGACT
ACCGGCGCATGCTCGTCGAATCGCTGTGA

Upstream 100 bases:

>100_bases
TGCGCCGCGCCCGGCGTCGCATGTTCGCCCGGACGGCGGCCGCTTGTCCAGCGCCGCGCGGCGGGGCGATTCGAACGAGC
ACGATCGAAGGAGACTTCCG

Downstream 100 bases:

>100_bases
CGGCGGCGCGCGTTGCGTCGCGGGCGACTGGGCGGACCTGTTCGCCGGTGTTGTCGCACGCGTGTTCACGGGCGTTTGGG
CGGCCGCGTTCACGCGCCCC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAYIYYLTHIHLGDDALAMLGAECARSGIARPLVVTDKGVAAAGLVDRALDALGLGALPVFDDTPSNPTEAAVLAAAQRY
RDEGCDGLVAVGGGSAIDLAKGVAIAATHPAPLTQYATIEGGSGRISAGVAPLIAVPTTSGTGSEVARGAILILADGRKL
GFHSWHLLPKAAICDPSLTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWAHIERATHDGGDRAARL
AMMSASMQGAMAFQKGLGCVHSLSHPLGGVKVNGKTSLHHGTLNAVVLPAVLRFNEHAPSVVAERRYARMRRVMNLPENA
DLPQALHDMTARLGLPTGLAQMGVDERVFDHVIEGALADHCHKTNPRVASADDYRRMLVESL

Sequences:

>Translated_382_residues
MAYIYYLTHIHLGDDALAMLGAECARSGIARPLVVTDKGVAAAGLVDRALDALGLGALPVFDDTPSNPTEAAVLAAAQRY
RDEGCDGLVAVGGGSAIDLAKGVAIAATHPAPLTQYATIEGGSGRISAGVAPLIAVPTTSGTGSEVARGAILILADGRKL
GFHSWHLLPKAAICDPSLTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWAHIERATHDGGDRAARL
AMMSASMQGAMAFQKGLGCVHSLSHPLGGVKVNGKTSLHHGTLNAVVLPAVLRFNEHAPSVVAERRYARMRRVMNLPENA
DLPQALHDMTARLGLPTGLAQMGVDERVFDHVIEGALADHCHKTNPRVASADDYRRMLVESL
>Mature_381_residues
AYIYYLTHIHLGDDALAMLGAECARSGIARPLVVTDKGVAAAGLVDRALDALGLGALPVFDDTPSNPTEAAVLAAAQRYR
DEGCDGLVAVGGGSAIDLAKGVAIAATHPAPLTQYATIEGGSGRISAGVAPLIAVPTTSGTGSEVARGAILILADGRKLG
FHSWHLLPKAAICDPSLTLGLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWAHIERATHDGGDRAARLA
MMSASMQGAMAFQKGLGCVHSLSHPLGGVKVNGKTSLHHGTLNAVVLPAVLRFNEHAPSVVAERRYARMRRVMNLPENAD
LPQALHDMTARLGLPTGLAQMGVDERVFDHVIEGALADHCHKTNPRVASADDYRRMLVESL

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=419, Percent_Identity=26.491646778043, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI48994951, Length=373, Percent_Identity=34.0482573726542, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87082107, Length=371, Percent_Identity=32.0754716981132, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789163, Length=375, Percent_Identity=30.4, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787493, Length=394, Percent_Identity=28.9340101522843, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789386, Length=353, Percent_Identity=30.028328611898, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17537053, Length=396, Percent_Identity=26.5151515151515, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321181, Length=364, Percent_Identity=34.6153846153846, Blast_Score=190, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24657991, Length=431, Percent_Identity=29.4663573085847, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 39723; Mature: 39592

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYIYYLTHIHLGDDALAMLGAECARSGIARPLVVTDKGVAAAGLVDRALDALGLGALPV
CEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCC
FDDTPSNPTEAAVLAAAQRYRDEGCDGLVAVGGGSAIDLAKGVAIAATHPAPLTQYATIE
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCEEEEEE
GGSGRISAGVAPLIAVPTTSGTGSEVARGAILILADGRKLGFHSWHLLPKAAICDPSLTL
CCCCEECCCCCEEEEECCCCCCCHHHHCCEEEEEECCCEECCCHHCCCCCHHHCCCCCEE
GLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWAHIERATHDGGDRAARL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHH
AMMSASMQGAMAFQKGLGCVHSLSHPLGGVKVNGKTSLHHGTLNAVVLPAVLRFNEHAPS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCHH
VVAERRYARMRRVMNLPENADLPQALHDMTARLGLPTGLAQMGVDERVFDHVIEGALADH
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHH
CHKTNPRVASADDYRRMLVESL
HHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AYIYYLTHIHLGDDALAMLGAECARSGIARPLVVTDKGVAAAGLVDRALDALGLGALPV
EEEEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCC
FDDTPSNPTEAAVLAAAQRYRDEGCDGLVAVGGGSAIDLAKGVAIAATHPAPLTQYATIE
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCEEEEEE
GGSGRISAGVAPLIAVPTTSGTGSEVARGAILILADGRKLGFHSWHLLPKAAICDPSLTL
CCCCEECCCCCEEEEECCCCCCCHHHHCCEEEEEECCCEECCCHHCCCCCHHHCCCCCEE
GLPPGLTAATGMDAIAHCIETFLAPAFNPPADGIALDGLERAWAHIERATHDGGDRAARL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHH
AMMSASMQGAMAFQKGLGCVHSLSHPLGGVKVNGKTSLHHGTLNAVVLPAVLRFNEHAPS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCHH
VVAERRYARMRRVMNLPENADLPQALHDMTARLGLPTGLAQMGVDERVFDHVIEGALADH
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHH
CHKTNPRVASADDYRRMLVESL
HHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]