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The map label for this gene is rep [H]

Identifier: 83719895

GI number: 83719895

Start: 3719191

End: 3721737

Strand: Direct

Name: rep [H]

Synonym: BTH_I3260

Alternate gene names: 83719895

Gene position: 3719191-3721737 (Clockwise)

Preceding gene: 83719858

Following gene: 83721535

Centisome position: 97.64

GC content: 65.96

Gene sequence:

>2547_bases
ATGCTCGACGGCGACGAGCAGGAGAATCGGACCGGCGACGACCGGCAGCCCGGCGAGCCAGCCCGCGATCGATGGCCCCC
ACCATCTGCCCGACATCGACACAAGCAGCAGGAACAGCGGGACCAGCGTGAGCTTCAGCGCGAGCATCGCGGGACGTCCG
GTAAAAAGGCGATGCTATCAGAACGCCTCGCGACGCGAAGACGCGCAGCGGCCATGCCGCATGCGTGCGTCACGTCGCCG
GCAGACGCCCCTGCCGCACGAGCGCCCGGCGCGCATCGGCCGAATGGCCGACGCGGCCGTCGTTTCACATACGCGAAAGA
ATCGCCGGCCGCCGCCGTGTTAACATGCGCGTCCCGCGAGCCATTTGCCGCGGCCGGCGCCGCCTTGCGCGCGCCGGCCG
CGCTTCGCTCGCGGCGCCTTCCGGCTTCGCCGCCGTCAACCGCAACACCATCCGCAATCATGTCCGCAGGCCTGAATCCC
GCTCAAAGCGAAGCGGTGCGCTATCTCGACGGTCCCTGCCTCGTGCTCGCCGGCGCGGGCAGCGGCAAGACCCGCGTCAT
CACGCAGAAGATCGCGCACCTGATCGAAGCAAAAGGCTTCGAGCCGCGCCACATCGCCGCCGTCACGTTCACGAACAAGG
CGGCCGCCGAAATGCGCGAGCGCGTCGGCAAGCTTCTCGAGGGCAAGACGCTCACGACGCCCGGCAAGGAAGGCCGCAAG
GTGCCCGTCAATCAGCTCACCGTCTGCACGTTCCATTCGCTCGGCGTGCAGATCCTGAGACAGGAGGCCGAGCACGTCGG
CCTGAAGCCGCAGTTCTCGATCATGGATTCGGACGACTGCTTCGGGATGATCCAAGAGCAGATCGGCACGACCGACAAGG
GCCTGATCCGCAAGATCCAGACGATCATCTCGCTGTGGAAGAACGGCCTCGTCACGCCCGAGGAGGCGATGACGATCGCG
GCGAACGAGGACGAGCACCAGGCGGCGCTCGTCTACCGGAACTACGTCGCGACGCTGCACGCGTACCAGGCGGTCGACTT
CGACGATCTGATCCGCCTGCCGACCGAGCTGTTCGCGAAGAACGAGCCGGTGCGCGACCGTTGGCAGAACCGGCTGCGCT
ACCTGCTGATCGACGAATACCAGGACACCAACGCGTGCCAGTACGAACTGCTCAAGCTGCTCGCGGGGCCGCGAGCGGCG
TTCACGGCGGTGGGCGACGACGATCAGGCGATCTACGGCTGGCGTGGAGCTACGCTCGAGAATCTCGCGCAACTCGGCAA
GGATTTTCCGAAGCTGCACGTGATCAAGCTCGAGCAGAACTATCGCTCGACGGTGCGCATTCTGACGGCGGCGAACAACG
TGATCGCGAACAACCCGAAGCTGTTCGAGAAGAAGCTGTGGTCCGAGCACGGGATGGGCGATTCGATCACCGTCACGCCG
TGCAACGACGAAGAGCACGAGGCCGAATCCGTCGTGTTCCGCCTGTCGGCGCACAAATTCGAGCGGCGCACCCAGTTTCG
CGACTACGCGATCCTGTACCGCGGCAACTTCCAGGCGCGCATCTTCGAGCAAGTGCTGCGGCGCGAGCGGATTCCATACG
TGCTGTCGGGCGGCCAGTCGTTCTTCGACAAGGCCGAGATCAAGGATCTGTGCGCGTACCTGCGCCTGATCGCGAACGCC
GACGACGATCCGGCGTTCATCCGCGCGGTCACGACGCCGCGCCGCGGGATCGGCAACACGACGCTCGAGGCGCTCGGCGC
GTTCGCCGGGCAGGCGAAGGTGTCGCTGTTCGAGGCGGTCTACATGGGCGGGATCGAGGCGCGGCTGTCCGCGCGGCAGA
TCGAGCCGCTGAGGATCTTCTGCGATTTCATCCAGCGCCTGACCGACCGCGCGGACAAGGAGCCCGCGACCGTCGTGCTC
GACGACATGATGGAAGCGATCCACTACGAAGCGTACCTGTACGACGCCTACGACGAACGGCAGGCGCAGACGAAGTGGCA
GAACGTGCTCGAATTCCTTGAATGGCTGAAGCGCAAGGGGACGAAGCCGGAGCCGGACGAGGCGGTGGACGGCGAGGCGG
AAGGCTTCCACAACGCGGACGGCCTCGCCGATACCGGCAAGAACCTGCTCGGGCTGATCCAGACGGTCGCGCTGATGTCG
ATGCTCGAAGGCAAGGAAGAAGATCCGGACGCGGTGCGCTTGTCGACCGTGCATGCGTCGAAGGGGCTCGAGTATCCGCA
CGTGTTCTTGGTCGGCGTCGAGGAAGGGATCATGCCGCACAGCGGCGGCAGCGACGACGGCCCGATCGACGACGAGCGGA
TCGAGGAAGAGCGCCGGCTGATGTACGTCGCGATCACGCGCGCGCAGCGCAGCCTGCATCTGAACTGGTGCAAGAAGCGC
AAGCGGGCGCGCGAGACAATCGTCTGCGAACAGTCGCGTTTCATCGCCGAGATGGGGCTCGACGAGGCGCCGCCGCCGAC
GCCGGAAGAGGCGCCGATGACGCCGAAGGATCGGCTCGCGAGCCTGAAGGCGCTGCTGCAGAAGTGA

Upstream 100 bases:

>100_bases
GGCGTTGGCGGCAGGTCCACGCATACGCGAAGTTGAACGCCTCGGACGCGGCGATTGCGGACAGCGACAGCAGCGCCGCT
TGCGCGCCGAAGGCGGGGCC

Downstream 100 bases:

>100_bases
GGTGGGCTGGCTGACGAGTTGACTGACTGGCGGCGCGGTGGCGGGCGACGTCGGTGGGTCCGTTGCGTCAGCCCGTTGTT
TCGGCCCGTTGTGTTCGATC

Product: ATP-dependent DNA helicase Rep

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MLDGDEQENRTGDDRQPGEPARDRWPPPSARHRHKQQEQRDQRELQREHRGTSGKKAMLSERLATRRRAAAMPHACVTSP
ADAPAARAPGAHRPNGRRGRRFTYAKESPAAAVLTCASREPFAAAGAALRAPAALRSRRLPASPPSTATPSAIMSAGLNP
AQSEAVRYLDGPCLVLAGAGSGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRK
VPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQTIISLWKNGLVTPEEAMTIA
ANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFAKNEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAA
FTAVGDDDQAIYGWRGATLENLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTP
CNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARIFEQVLRRERIPYVLSGGQSFFDKAEIKDLCAYLRLIANA
DDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAVYMGGIEARLSARQIEPLRIFCDFIQRLTDRADKEPATVVL
DDMMEAIHYEAYLYDAYDERQAQTKWQNVLEFLEWLKRKGTKPEPDEAVDGEAEGFHNADGLADTGKNLLGLIQTVALMS
MLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRLMYVAITRAQRSLHLNWCKKR
KRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLASLKALLQK

Sequences:

>Translated_848_residues
MLDGDEQENRTGDDRQPGEPARDRWPPPSARHRHKQQEQRDQRELQREHRGTSGKKAMLSERLATRRRAAAMPHACVTSP
ADAPAARAPGAHRPNGRRGRRFTYAKESPAAAVLTCASREPFAAAGAALRAPAALRSRRLPASPPSTATPSAIMSAGLNP
AQSEAVRYLDGPCLVLAGAGSGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRK
VPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQTIISLWKNGLVTPEEAMTIA
ANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFAKNEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAA
FTAVGDDDQAIYGWRGATLENLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTP
CNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARIFEQVLRRERIPYVLSGGQSFFDKAEIKDLCAYLRLIANA
DDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAVYMGGIEARLSARQIEPLRIFCDFIQRLTDRADKEPATVVL
DDMMEAIHYEAYLYDAYDERQAQTKWQNVLEFLEWLKRKGTKPEPDEAVDGEAEGFHNADGLADTGKNLLGLIQTVALMS
MLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRLMYVAITRAQRSLHLNWCKKR
KRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLASLKALLQK
>Mature_848_residues
MLDGDEQENRTGDDRQPGEPARDRWPPPSARHRHKQQEQRDQRELQREHRGTSGKKAMLSERLATRRRAAAMPHACVTSP
ADAPAARAPGAHRPNGRRGRRFTYAKESPAAAVLTCASREPFAAAGAALRAPAALRSRRLPASPPSTATPSAIMSAGLNP
AQSEAVRYLDGPCLVLAGAGSGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRK
VPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQTIISLWKNGLVTPEEAMTIA
ANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFAKNEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAA
FTAVGDDDQAIYGWRGATLENLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTP
CNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARIFEQVLRRERIPYVLSGGQSFFDKAEIKDLCAYLRLIANA
DDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAVYMGGIEARLSARQIEPLRIFCDFIQRLTDRADKEPATVVL
DDMMEAIHYEAYLYDAYDERQAQTKWQNVLEFLEWLKRKGTKPEPDEAVDGEAEGFHNADGLADTGKNLLGLIQTVALMS
MLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRLMYVAITRAQRSLHLNWCKKR
KRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLASLKALLQK

Specific function: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI48994965, Length=701, Percent_Identity=47.0756062767475, Blast_Score=590, Evalue=1e-169,
Organism=Escherichia coli, GI2367296, Length=669, Percent_Identity=35.7249626307922, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322369, Length=730, Percent_Identity=28.7671232876712, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324477, Length=676, Percent_Identity=23.5207100591716, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005752
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 94770; Mature: 94770

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDGDEQENRTGDDRQPGEPARDRWPPPSARHRHKQQEQRDQRELQREHRGTSGKKAMLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ERLATRRRAAAMPHACVTSPADAPAARAPGAHRPNGRRGRRFTYAKESPAAAVLTCASRE
HHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCC
PFAAAGAALRAPAALRSRRLPASPPSTATPSAIMSAGLNPAQSEAVRYLDGPCLVLAGAG
CHHHHCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECC
SGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRK
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQ
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHH
TIISLWKNGLVTPEEAMTIAANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFAK
HHHHHHHCCCCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHC
NEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAAFTAVGDDDQAIYGWRGATLE
CCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCHH
NLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTP
HHHHHCCCCCCEEEEEECCCCHHHEEHHHHCCCHHCCCCHHHHHHHHHHCCCCCEEEEEC
CNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARIFEQVLRRERIPYVLSGGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHH
FFDKAEIKDLCAYLRLIANADDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHHH
YMGGIEARLSARQIEPLRIFCDFIQRLTDRADKEPATVVLDDMMEAIHYEAYLYDAYDER
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCHHHH
QAQTKWQNVLEFLEWLKRKGTKPEPDEAVDGEAEGFHNADGLADTGKNLLGLIQTVALMS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRL
HHCCCCCCCCCEEEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHE
MYVAITRAQRSLHLNWCKKRKRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLA
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
SLKALLQK
HHHHHHCC
>Mature Secondary Structure
MLDGDEQENRTGDDRQPGEPARDRWPPPSARHRHKQQEQRDQRELQREHRGTSGKKAMLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ERLATRRRAAAMPHACVTSPADAPAARAPGAHRPNGRRGRRFTYAKESPAAAVLTCASRE
HHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCC
PFAAAGAALRAPAALRSRRLPASPPSTATPSAIMSAGLNPAQSEAVRYLDGPCLVLAGAG
CHHHHCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECC
SGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRK
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQ
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHH
TIISLWKNGLVTPEEAMTIAANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFAK
HHHHHHHCCCCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHC
NEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAAFTAVGDDDQAIYGWRGATLE
CCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCHH
NLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTP
HHHHHCCCCCCEEEEEECCCCHHHEEHHHHCCCHHCCCCHHHHHHHHHHCCCCCEEEEEC
CNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARIFEQVLRRERIPYVLSGGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHH
FFDKAEIKDLCAYLRLIANADDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHHH
YMGGIEARLSARQIEPLRIFCDFIQRLTDRADKEPATVVLDDMMEAIHYEAYLYDAYDER
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCHHHH
QAQTKWQNVLEFLEWLKRKGTKPEPDEAVDGEAEGFHNADGLADTGKNLLGLIQTVALMS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRL
HHCCCCCCCCCEEEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHE
MYVAITRAQRSLHLNWCKKRKRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLA
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
SLKALLQK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]