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The map label for this gene is csgA [H]

Identifier: 83719877

GI number: 83719877

Start: 380264

End: 380941

Strand: Reverse

Name: csgA [H]

Synonym: BTH_I0343

Alternate gene names: 83719877

Gene position: 380941-380264 (Counterclockwise)

Preceding gene: 83720193

Following gene: 83720466

Centisome position: 10.0

GC content: 73.01

Gene sequence:

>678_bases
ATGAAGACCGTATTGATCGTCGGCGCATCGCGCGGCATCGGCCGCGAATTCGTCGGCCAATATCTGCGCGACGGGTGGCG
CGTGATCGCCACCGCGCGCGACGCGGCGTCGCTCGCGTCGCTCGATGCGCTCGGCGCGCGCACGCTCGCGCTCGACGTCG
CGCGGCCCGACGACGTCGCGGCGTTCGACGCGCGGCTCGGCGACACCGCGCTCGACGCGGCCGTCGTCGTATCGGGCGTG
TACGGCCCGCGCACGGCGGGCGTCGAGCCCGTCGGCGCGGAGGACTTCGATGCGGTGATGCATACGAACGTGCTCGGCCC
GATGCTGCTGATGCCGATCCTGCTGCCGCTCGTCGAGGCGAGCCGCGGCGTCCTCGCGGTGCTGTCGAGCAAGATGGGCA
GCATCAGCGAGGCGACCGGCACGACGGGCTGGCTCTATCGCGCGAGCAAGGCCGCGGTGAACGACGCGCTCAAGATCGCG
TCGCTGCAGGCGCGGCACGCGGCCTGCATCGCGCTGCATCCGGGCTGGGTGCGCACCGACATGGGCGGCGCGCAAGCCGC
GCTCGAACCGCAGGCGAGCGTCGCCGGCATGCGCCGCGTGATCGCGCAGGCGGCGGGCGACCGCGAGCGCGCGAACGGCC
GCTTCTTCCAATACGACGGCGTCGAGCTCGGCTGGTGA

Upstream 100 bases:

>100_bases
AGCGCGGCGTCGCGAGCCTGTGCATCGGCGGCGGCGAGGCGACCGCGATGGGCATCGAGCTGATCTGACTTCCGCCGCGC
CCCCGAACAGGAGTCCTCCG

Downstream 100 bases:

>100_bases
GCCGGCGCGCCGCCGTCGCTCCTCGAATCACGATGCAAGCCACAACGAATGTCTCCGAGCGCCCGCTCGATTGCCCGTGC
GGCGGCGCCGCGCCCGGCGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGIGREFVGQYLRDGWRVIATARDAASLASLDALGARTLALDVARPDDVAAFDARLGDTALDAAVVVSGV
YGPRTAGVEPVGAEDFDAVMHTNVLGPMLLMPILLPLVEASRGVLAVLSSKMGSISEATGTTGWLYRASKAAVNDALKIA
SLQARHAACIALHPGWVRTDMGGAQAALEPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW

Sequences:

>Translated_225_residues
MKTVLIVGASRGIGREFVGQYLRDGWRVIATARDAASLASLDALGARTLALDVARPDDVAAFDARLGDTALDAAVVVSGV
YGPRTAGVEPVGAEDFDAVMHTNVLGPMLLMPILLPLVEASRGVLAVLSSKMGSISEATGTTGWLYRASKAAVNDALKIA
SLQARHAACIALHPGWVRTDMGGAQAALEPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
>Mature_225_residues
MKTVLIVGASRGIGREFVGQYLRDGWRVIATARDAASLASLDALGARTLALDVARPDDVAAFDARLGDTALDAAVVVSGV
YGPRTAGVEPVGAEDFDAVMHTNVLGPMLLMPILLPLVEASRGVLAVLSSKMGSISEATGTTGWLYRASKAAVNDALKIA
SLQARHAACIALHPGWVRTDMGGAQAALEPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=247, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193207563, Length=250, Percent_Identity=30, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=28.6290322580645, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558990, Length=245, Percent_Identity=30.2040816326531, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559962, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558992, Length=241, Percent_Identity=30.2904564315353, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23513; Mature: 23513

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGIGREFVGQYLRDGWRVIATARDAASLASLDALGARTLALDVARPDDVA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCHH
AFDARLGDTALDAAVVVSGVYGPRTAGVEPVGAEDFDAVMHTNVLGPMLLMPILLPLVEA
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SRGVLAVLSSKMGSISEATGTTGWLYRASKAAVNDALKIASLQARHAACIALHPGWVRTD
CCCHHHHHHHHCCCCHHCCCCCHHEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAALEPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
CCCCCHHCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEECCEEECC
>Mature Secondary Structure
MKTVLIVGASRGIGREFVGQYLRDGWRVIATARDAASLASLDALGARTLALDVARPDDVA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCHH
AFDARLGDTALDAAVVVSGVYGPRTAGVEPVGAEDFDAVMHTNVLGPMLLMPILLPLVEA
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SRGVLAVLSSKMGSISEATGTTGWLYRASKAAVNDALKIASLQARHAACIALHPGWVRTD
CCCHHHHHHHHCCCCHHCCCCCHHEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAALEPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
CCCCCHHCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]