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The map label for this gene is cobB [H]

Identifier: 83719873

GI number: 83719873

Start: 2745714

End: 2747219

Strand: Direct

Name: cobB [H]

Synonym: BTH_I2412

Alternate gene names: 83719873

Gene position: 2745714-2747219 (Clockwise)

Preceding gene: 83719821

Following gene: 83720608

Centisome position: 72.08

GC content: 74.63

Gene sequence:

>1506_bases
ATGCCCGCCTGCCCCGCGCTCTTCGTCGCCGCCGCCGCGTCCGGCCAGGGCAAGACGTCGGTGACGGCGGCGCTCGCGCG
CCATCACCGGCGGCTCGGCCGGCGCGTGCGCGTGTTCAAGACCGGCCCGGATTTTCTCGATCCGATGCTGCTCGCGCGCG
CGAGCGGCGCGAGCGTCTATTCGCTCGATCTCGGGATGGTCGGCGAGCGCGGCTGCCGCGCGCTGCTTGCGCGCGCCGCG
GCCGAAGCGGACGTGATCCTGATCGAAGGCGCGATGGGGCTCTTTGACGGCACGCCGTCGAGCGCCGATCTCGCGCAGGC
GTTCGGCGTGCCCGTCGCCGCGGTGATCGCCGCGCAATCGATGGCGCAGACCTTCGCCGCGCTCGCGTTCGGGCTCGTGC
ATTTCCGGCCCGGCGTGCCGTTTCACGGCGTGCTCGCGAACCGCGTCGGCTCCGAGCGCCATGCGCGGTTGCTGCGCAGC
GCGCTGCCCGAGTCGATCCGCTGGCTCGGCCACCTGCCGCGCGATGCGCAGATCGCGCTGCCGGAGCGCCACCTCGGGCT
GCACCAGCCGGACGACGTCGCCGATCTCGACGCGCGGCTCGACCGCGCGGCCGACGCGATCGCGCGCACCGCGCTCGCCG
ATCTGCCGCCCGTCGTCGAGTTCGCGCTCGGCGACGATGCGAATGTCGACGACCACGGCGGCGGAACGGTTGCGACGCTG
GATGCCGCGCGCGGCCATCGTCGCGCGCCGTCGGCGGCAAGCGTGGCCGCAGACCGCGACGATGCCGCGGCGGCGATGCC
CCCCGTCGACTCCGCCAACGAAGCGAATGCGGCGGCAAATCGCCCGGCGCACGGCGGCGGCGCGTCCGGCGCATCGGCCG
GCGCGGCGCGCGCCGAACCGCCCCTTGCCGGCAGGCGGATCGCGATCGCGCGCGACGCGGCGTTCTCGTTCATCTATCCG
GCGAACCTCGATCAGTTGGAAGCGCTCGGCGCCGAGCTCGCATTCTTCTCGCCGCTCGCCGACGAGCCAGTGCCCGACGG
TTCCGCCGCGCTCTATCTGCCGGGCGGCTATCCGGAGCTGCATGCGGCGCGGCTCGCGGCGAACGCGACGGCCGCGCGCT
CGATCGCCGCGCACGTCGCGGCGGGCCGGCGCGTCGTCGCCGAGTGCGGCGGGATGCTGTACCTGAGCGAAACGCTCACC
GACGCCGACGGCGCGACGACGCCGATGCTCGGCCTCGTGCCCGGCCACGCGACGATGCAGCGGCGCTTCGCCGCGCTCGG
CATGCAGACCCTCGCGACGCGCTTCGGCGCGATGACCGGCCACACGTTCCACTATTCGCGCTTCGCGACGCCGCTCGCGC
CCGTCGCCGCCGCGACGCGGCCGGACGACGGCGCGGCGGGCGAAGCGGTGTATCGGCACGGGCCGATCGTCGCGACGTAT
CTGCACGCGTACTGGCCGTCGAATCCGCGTGCGGCGGCCGCGCTTTTCGCGCTCGACGCGCTGTAG

Upstream 100 bases:

>100_bases
CTCGTCGACGCGGCCGACCTCGTCACCGAGATGCGGCTCGTCAAGCATCCGTACAAGGAGCAAGGCGTGAAGGCGCAGCG
CGGCGTGGAGTTCTGACGCG

Downstream 100 bases:

>100_bases
CCCCCGCGCGACCGCCTCGAAGGCACGGGTGTAATTCCGTGTAATGGCGCATCGATTCGCGCCTTCCTAGCATGGTCATA
TCGTCGGCACGCATCGCCGG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGASVYSLDLGMVGERGCRALLARAA
AEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFAALAFGLVHFRPGVPFHGVLANRVGSERHARLLRS
ALPESIRWLGHLPRDAQIALPERHLGLHQPDDVADLDARLDRAADAIARTALADLPPVVEFALGDDANVDDHGGGTVATL
DAARGHRRAPSAASVAADRDDAAAAMPPVDSANEANAAANRPAHGGGASGASAGAARAEPPLAGRRIAIARDAAFSFIYP
ANLDQLEALGAELAFFSPLADEPVPDGSAALYLPGGYPELHAARLAANATAARSIAAHVAAGRRVVAECGGMLYLSETLT
DADGATTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRFATPLAPVAAATRPDDGAAGEAVYRHGPIVATY
LHAYWPSNPRAAAALFALDAL

Sequences:

>Translated_501_residues
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGASVYSLDLGMVGERGCRALLARAA
AEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFAALAFGLVHFRPGVPFHGVLANRVGSERHARLLRS
ALPESIRWLGHLPRDAQIALPERHLGLHQPDDVADLDARLDRAADAIARTALADLPPVVEFALGDDANVDDHGGGTVATL
DAARGHRRAPSAASVAADRDDAAAAMPPVDSANEANAAANRPAHGGGASGASAGAARAEPPLAGRRIAIARDAAFSFIYP
ANLDQLEALGAELAFFSPLADEPVPDGSAALYLPGGYPELHAARLAANATAARSIAAHVAAGRRVVAECGGMLYLSETLT
DADGATTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRFATPLAPVAAATRPDDGAAGEAVYRHGPIVATY
LHAYWPSNPRAAAALFALDAL
>Mature_500_residues
PACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGASVYSLDLGMVGERGCRALLARAAA
EADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFAALAFGLVHFRPGVPFHGVLANRVGSERHARLLRSA
LPESIRWLGHLPRDAQIALPERHLGLHQPDDVADLDARLDRAADAIARTALADLPPVVEFALGDDANVDDHGGGTVATLD
AARGHRRAPSAASVAADRDDAAAAMPPVDSANEANAAANRPAHGGGASGASAGAARAEPPLAGRRIAIARDAAFSFIYPA
NLDQLEALGAELAFFSPLADEPVPDGSAALYLPGGYPELHAARLAANATAARSIAAHVAAGRRVVAECGGMLYLSETLTD
ADGATTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRFATPLAPVAAATRPDDGAAGEAVYRHGPIVATYL
HAYWPSNPRAAAALFALDAL

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 51596; Mature: 51465

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGASVY
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEE
SLDLGMVGERGCRALLARAAAEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQS
EEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
MAQTFAALAFGLVHFRPGVPFHGVLANRVGSERHARLLRSALPESIRWLGHLPRDAQIAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
PERHLGLHQPDDVADLDARLDRAADAIARTALADLPPVVEFALGDDANVDDHGGGTVATL
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCEEEEE
DAARGHRRAPSAASVAADRDDAAAAMPPVDSANEANAAANRPAHGGGASGASAGAARAEP
ECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLAGRRIAIARDAAFSFIYPANLDQLEALGAELAFFSPLADEPVPDGSAALYLPGGYPEL
CCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHH
HAARLAANATAARSIAAHVAAGRRVVAECGGMLYLSETLTDADGATTPMLGLVPGHATMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCEEEECCCHHHHH
RRFAALGMQTLATRFGAMTGHTFHYSRFATPLAPVAAATRPDDGAAGEAVYRHGPIVATY
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCHHHHHHCCCCCCCCCCCHHHHCCCCCEEH
LHAYWPSNPRAAAALFALDAL
HHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGASVY
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEE
SLDLGMVGERGCRALLARAAAEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQS
EEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
MAQTFAALAFGLVHFRPGVPFHGVLANRVGSERHARLLRSALPESIRWLGHLPRDAQIAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
PERHLGLHQPDDVADLDARLDRAADAIARTALADLPPVVEFALGDDANVDDHGGGTVATL
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCEEEEE
DAARGHRRAPSAASVAADRDDAAAAMPPVDSANEANAAANRPAHGGGASGASAGAARAEP
ECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLAGRRIAIARDAAFSFIYPANLDQLEALGAELAFFSPLADEPVPDGSAALYLPGGYPEL
CCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHH
HAARLAANATAARSIAAHVAAGRRVVAECGGMLYLSETLTDADGATTPMLGLVPGHATMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCEEEECCCHHHHH
RRFAALGMQTLATRFGAMTGHTFHYSRFATPLAPVAAATRPDDGAAGEAVYRHGPIVATY
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCHHHHHHCCCCCCCCCCCHHHHCCCCCEEH
LHAYWPSNPRAAAALFALDAL
HHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]