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The map label for this gene is rutG [H]

Identifier: 83719835

GI number: 83719835

Start: 286115

End: 287776

Strand: Direct

Name: rutG [H]

Synonym: BTH_I0252

Alternate gene names: 83719835

Gene position: 286115-287776 (Clockwise)

Preceding gene: 83720036

Following gene: 83721524

Centisome position: 7.51

GC content: 68.53

Gene sequence:

>1662_bases
GTGTTCGGCTCGGGGCTTTCGCCGGGCGCGGGCGGCGCCGAGGCGTCATACGTTGGGACGAAGCGGGCGGCGCGTGCCGC
CCGCTTTGTTTTGGGGCGGGGCGGCCGCGTTGTCGCCGCTTGCCGTCGCATACCTGCGCATGCATCCGCGTATCCGCATG
CATCCGCCGCCGCGCGCGGCCCGCGTGCGTTTCCTTACCCGTTCCTTGCGTTTGCCCCCCGCGCGCCCCCCGCGCGGCGG
GTGTTTTTGCGCGCCGCTTGTCAGCGCGATTCCCGCTTCGTACACTCGCGCGTGATTTTTACCTTGACGCGCCGTCGCGC
GCGCCTCAATCCAGACAACCAGGAGAATCCCGCGATGGCCGATTCCTATTTTCCGCGGTGGCGCGCGCAGCCGCGCGACG
ACGCGGCCCGCGTCGTCGCGCCCGACGAGCGCCTGCCGTGGCCGCAGACCTTCGCGATGGGCGTGCAGCACGTCGTCGCG
ATGTTCGGCTCGACCGTGCTCGCGCCGCTGCTGATGGGCTTCGATCCGAATCTCTGCATCCTGATGTCCGGGATCGGCAC
GCTGCTGTTCTTCGTGCTCGTAGGCGGGCGCGTGCCGAGCTATCTCGGCTCGAGCTTCGCGTTCATCGGCCTCGTGATCG
CCGTGACGGGCTACGCCGGCGGCGGCGCGAATCCGAACATTCCCGTCGCGCTCGGCGGGATCGTCGCGTGCGGCGTCGTC
TATGCGCTGATCGGGCTCGTCGTGTCCGCGGTCGGCACGCGCTGGATCGAGACGCTGATGCCGCCCGTCGTCACGGGCGC
GATCGTCGCGGTGATCGGGCTCAATCTCGCGCCGATCGCGGTGAAGAGCGTGTCCGCGTCGACCTTCGATTCGACGCTCG
CGCTCGTGACCGTGCTGTGCGTCGGCGGCGTCGCCGTGTTCGCGCGCGGGATGTTGCAGCGGCTGCTGATTCTCGTCGGC
GTAGTGATCGCGTACGCGATCTACGCGGCGCTCACGAACGGCATGGGGCTCGGCAAGCCGATCGATTTCGCGATCGTCGC
GCATGCCGCATGGTTCGGCGTGCCGACGTTCCATCGGCCCGTGTTCGATCCGCACGCGATGCTGCTGATCGCGCCCGTCG
CCGTGATCCTCGTCGCGGAGAATCTCGGCCACATCAAGGCGGTGAGCGCGATGACGGGCCGCAATCTGGACCGCTACGTC
GGCCGCGCGTTCATCGGCGACGGCCTGGCGACGATCGTCTCGGGCAGCATGGGCGGCACGGGCGTGACGACGTATGCGGA
GAACATCGGCGTGATGGCGGTGACGAGAATCTATTCGACGCTCGTGTTCGTCGCGGCCGCGCTGATCGCGATCCTGCTCG
GCTTTTCGCCGAAGTTCGGCGCGGTGATCCAGACGATTCCGGGGCCGGTGCTGGGCGGCGTGTCGATCGTCGTGTTCGGC
CTGATCGCGGTGACGGGCGCGCGGATCTGGGTCGTGAACCGCGTCGATTTCTCCGACAACCGGAATCTGATCGTCGCAGC
GGTCACGCTCGTGCTCGGCGCGGGTGATTTCTCGCTGAAGCTGGGCGGCTTCGCGCTCGGCGGAATCGGCACCGCGACGT
TCGGCGCGATCATCCTCTATGCGCTGCTGCGCAAGGAGAAGGAGCCGGGGCCGATGGTGTGA

Upstream 100 bases:

>100_bases
CGCTGTTCCAGTATCTGAACCCGTAAGCGGCGCCGGCGCGCGCGGCACGCTCGGCGGCGGTCACGCTATCGGCGAGGCGG
TCCGGGCGACGGTCGGTGCG

Downstream 100 bases:

>100_bases
GCGCGCGGGCGCCGACGATGCGTGCCGCTCGATGCGCGGGCGGTGAGATGACGCGGCGGCCGTTTTCCGCGTTCATCGGC
GATCGAGCCGCGCCGGGCGG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MFGSGLSPGAGGAEASYVGTKRAARAARFVLGRGGRVVAACRRIPAHASAYPHASAAARGPRAFPYPFLAFAPRAPPARR
VFLRAACQRDSRFVHSRVIFTLTRRRARLNPDNQENPAMADSYFPRWRAQPRDDAARVVAPDERLPWPQTFAMGVQHVVA
MFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAVTGYAGGGANPNIPVALGGIVACGVV
YALIGLVVSAVGTRWIETLMPPVVTGAIVAVIGLNLAPIAVKSVSASTFDSTLALVTVLCVGGVAVFARGMLQRLLILVG
VVIAYAIYAALTNGMGLGKPIDFAIVAHAAWFGVPTFHRPVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYV
GRAFIGDGLATIVSGSMGGTGVTTYAENIGVMAVTRIYSTLVFVAAALIAILLGFSPKFGAVIQTIPGPVLGGVSIVVFG
LIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFSLKLGGFALGGIGTATFGAIILYALLRKEKEPGPMV

Sequences:

>Translated_553_residues
MFGSGLSPGAGGAEASYVGTKRAARAARFVLGRGGRVVAACRRIPAHASAYPHASAAARGPRAFPYPFLAFAPRAPPARR
VFLRAACQRDSRFVHSRVIFTLTRRRARLNPDNQENPAMADSYFPRWRAQPRDDAARVVAPDERLPWPQTFAMGVQHVVA
MFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAVTGYAGGGANPNIPVALGGIVACGVV
YALIGLVVSAVGTRWIETLMPPVVTGAIVAVIGLNLAPIAVKSVSASTFDSTLALVTVLCVGGVAVFARGMLQRLLILVG
VVIAYAIYAALTNGMGLGKPIDFAIVAHAAWFGVPTFHRPVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYV
GRAFIGDGLATIVSGSMGGTGVTTYAENIGVMAVTRIYSTLVFVAAALIAILLGFSPKFGAVIQTIPGPVLGGVSIVVFG
LIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFSLKLGGFALGGIGTATFGAIILYALLRKEKEPGPMV
>Mature_553_residues
MFGSGLSPGAGGAEASYVGTKRAARAARFVLGRGGRVVAACRRIPAHASAYPHASAAARGPRAFPYPFLAFAPRAPPARR
VFLRAACQRDSRFVHSRVIFTLTRRRARLNPDNQENPAMADSYFPRWRAQPRDDAARVVAPDERLPWPQTFAMGVQHVVA
MFGSTVLAPLLMGFDPNLCILMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAVTGYAGGGANPNIPVALGGIVACGVV
YALIGLVVSAVGTRWIETLMPPVVTGAIVAVIGLNLAPIAVKSVSASTFDSTLALVTVLCVGGVAVFARGMLQRLLILVG
VVIAYAIYAALTNGMGLGKPIDFAIVAHAAWFGVPTFHRPVFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYV
GRAFIGDGLATIVSGSMGGTGVTTYAENIGVMAVTRIYSTLVFVAAALIAILLGFSPKFGAVIQTIPGPVLGGVSIVVFG
LIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFSLKLGGFALGGIGTATFGAIILYALLRKEKEPGPMV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=428, Percent_Identity=72.4299065420561, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1788843, Length=429, Percent_Identity=38.9277389277389, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI87082181, Length=474, Percent_Identity=25.7383966244726, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1790087, Length=469, Percent_Identity=25.5863539445629, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082178, Length=408, Percent_Identity=25.2450980392157, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=31.4917127071823, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=219, Percent_Identity=28.310502283105, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71993493, Length=174, Percent_Identity=32.183908045977, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=174, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=114, Percent_Identity=36.8421052631579, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 57616; Mature: 57616

Theoretical pI: Translated: 10.94; Mature: 10.94

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGSGLSPGAGGAEASYVGTKRAARAARFVLGRGGRVVAACRRIPAHASAYPHASAAARG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHCCC
PRAFPYPFLAFAPRAPPARRVFLRAACQRDSRFVHSRVIFTLTRRRARLNPDNQENPAMA
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DSYFPRWRAQPRDDAARVVAPDERLPWPQTFAMGVQHVVAMFGSTVLAPLLMGFDPNLCI
HHCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAVTGYAGGGANPNIPVALGGIVACGVV
HHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
YALIGLVVSAVGTRWIETLMPPVVTGAIVAVIGLNLAPIAVKSVSASTFDSTLALVTVLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHH
VGGVAVFARGMLQRLLILVGVVIAYAIYAALTNGMGLGKPIDFAIVAHAAWFGVPTFHRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC
VFDPHAMLLIAPVAVILVAENLGHIKAVSAMTGRNLDRYVGRAFIGDGLATIVSGSMGGT
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCC
GVTTYAENIGVMAVTRIYSTLVFVAAALIAILLGFSPKFGAVIQTIPGPVLGGVSIVVFG
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHH
LIAVTGARIWVVNRVDFSDNRNLIVAAVTLVLGAGDFSLKLGGFALGGIGTATFGAIILY
HHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCHHHHHHHHHHHH
ALLRKEKEPGPMV
HHHHCCCCCCCCC
>Mature Secondary Structure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HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]