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The map label for this gene is trpC [H]

Identifier: 83719789

GI number: 83719789

Start: 3347622

End: 3348407

Strand: Direct

Name: trpC [H]

Synonym: BTH_I2912

Alternate gene names: 83719789

Gene position: 3347622-3348407 (Clockwise)

Preceding gene: 83720272

Following gene: 83718843

Centisome position: 87.88

GC content: 67.18

Gene sequence:

>786_bases
ATGAGCGACATCCTCGACAAAATCATCGCCGTCAAGCGCGAAGAGATCGCCGCCGCACTCAAGAGCGCGCCGCTCGAAGA
ACTGAAGCTGCAGGCGTCGGCGCGCGATTCGCGCGACTTCGTCGGCGCGCTGCGCGGCAAGCATGCGGCCGGACACGCCG
CCGTCATCGCCGAGGTGAAGAAGGCGAGCCCGTCGAAAGGCGTGCTGCGCGAGCGCTTCGTGCCGGCCGACATCGCCCGC
TCGTACGCGGAGCACGGCGCCGCATGCCTGTCGGTGCTGACCGACGAGCAGTTCTTCCAGGGCAGCGCGCGCTATCTGGA
AGAGGCGCGCGCCGCATGCAACCTGCCCGTGCTGCGCAAGGACTTCATCGTCGACCCGTATCAGGTGCTCGAAGCGCGCG
CGATGGGCGCGGACGCGATCCTGCTGATCGCCGCCGCACTCGATACGCCGCTGATGGTCGATCTCGAGGCGTACGCGCAT
TCGCTCGGGCTCGCGGTGCTCGTCGAGGTGCACAACCGCGACGAACTGAGCGCGGCGCTCGAACTGAAGACGCCGCTCGT
CGGCATCAACAACCGCAACCTGCGCACGTTCGAGACGACGATCGACACGACGCTCGGCATGCTCGACGCGATTCCGGACG
ACCGCATCGTCGTCACCGAATCGGGCATCCTGTCGCGCGCGGACGTCGAGCGAATGGAAGCGGCGGGCGTGCATACGTTC
CTCGTCGGCGAAGCGTTCATGCGCGCCGAGAATCCGGGCGCGGAACTCGCGCGGATGTTCTTCTGA

Upstream 100 bases:

>100_bases
GAAGGTCGACGAGCTCGCGCGCTTCACGCAGCAGTTCAAGCGCTGATCCGGCGCCTCGCGCCTCAACCGAATCCGAATCC
AGCACGCAGGGCAGACATCC

Downstream 100 bases:

>100_bases
GCGGCCCGCGATGGCGATCGAACAGGAAATCAAGCTCGCGCTGCCCGCCGCGCAAGTCGACGCGGCGCGGCGCTTTCTCG
ATGCGCGCGCCGGCGCCAGC

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSDILDKIIAVKREEIAAALKSAPLEELKLQASARDSRDFVGALRGKHAAGHAAVIAEVKKASPSKGVLRERFVPADIAR
SYAEHGAACLSVLTDEQFFQGSARYLEEARAACNLPVLRKDFIVDPYQVLEARAMGADAILLIAAALDTPLMVDLEAYAH
SLGLAVLVEVHNRDELSAALELKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTF
LVGEAFMRAENPGAELARMFF

Sequences:

>Translated_261_residues
MSDILDKIIAVKREEIAAALKSAPLEELKLQASARDSRDFVGALRGKHAAGHAAVIAEVKKASPSKGVLRERFVPADIAR
SYAEHGAACLSVLTDEQFFQGSARYLEEARAACNLPVLRKDFIVDPYQVLEARAMGADAILLIAAALDTPLMVDLEAYAH
SLGLAVLVEVHNRDELSAALELKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTF
LVGEAFMRAENPGAELARMFF
>Mature_260_residues
SDILDKIIAVKREEIAAALKSAPLEELKLQASARDSRDFVGALRGKHAAGHAAVIAEVKKASPSKGVLRERFVPADIARS
YAEHGAACLSVLTDEQFFQGSARYLEEARAACNLPVLRKDFIVDPYQVLEARAMGADAILLIAAALDTPLMVDLEAYAHS
LGLAVLVEVHNRDELSAALELKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTFL
VGEAFMRAENPGAELARMFF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=261, Percent_Identity=39.0804597701149, Blast_Score=157, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6322638, Length=261, Percent_Identity=39.8467432950192, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28281; Mature: 28150

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILDKIIAVKREEIAAALKSAPLEELKLQASARDSRDFVGALRGKHAAGHAAVIAEVK
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHH
KASPSKGVLRERFVPADIARSYAEHGAACLSVLTDEQFFQGSARYLEEARAACNLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DFIVDPYQVLEARAMGADAILLIAAALDTPLMVDLEAYAHSLGLAVLVEVHNRDELSAAL
HHCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEHHHHHHHCCCEEEEEECCCHHHHHHH
ELKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTF
EECCCEEECCCCCCEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCHHHH
LVGEAFMRAENPGAELARMFF
HHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
SDILDKIIAVKREEIAAALKSAPLEELKLQASARDSRDFVGALRGKHAAGHAAVIAEVK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHH
KASPSKGVLRERFVPADIARSYAEHGAACLSVLTDEQFFQGSARYLEEARAACNLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DFIVDPYQVLEARAMGADAILLIAAALDTPLMVDLEAYAHSLGLAVLVEVHNRDELSAAL
HHCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEHHHHHHHCCCEEEEEECCCHHHHHHH
ELKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTF
EECCCEEECCCCCCEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCHHHH
LVGEAFMRAENPGAELARMFF
HHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA