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The map label for this gene is nadB [H]

Identifier: 83719697

GI number: 83719697

Start: 896454

End: 898055

Strand: Reverse

Name: nadB [H]

Synonym: BTH_I0778

Alternate gene names: 83719697

Gene position: 898055-896454 (Counterclockwise)

Preceding gene: 83720063

Following gene: 83719780

Centisome position: 23.58

GC content: 67.92

Gene sequence:

>1602_bases
ATGAATTTCGATGTGGCGATCGTGGGCAGCGGCCTCGCCGGTCTGTCGGTCGCGCTCAATCTCGCTCAAACGCGCCGCGT
CGCGCTGATCGCGAAGCGCTCGATGATGGAGGGCGCGAGCGACTACGCGCAAGGCGGCATCGCCGCAGTGCTCGATTCGG
CGGACAGCGTCGAGAATCACGTGAACGACACGCTGATCGCAGGCGGCGGCCTGTGCGACGAAGCCGCGACGCGCTACATC
GTCGAGCACGGCCGCGAGGCAATCGAATGGCTGATCTCGCAAGGCGTGCCGTTCACGAAGGACGACGCCGCCGAACTCGG
CTTTCACCTGACGCGCGAAGGCGGCCATAGCCATCGCCGCATCATCCACGCGGCCGACGCGACGGGCCACGCGGTGCTCG
CGACGCTGTCCGAGCGTGCCCGCACGCATCCGAACATCACGTTCTTCGAGGATCACCATGCGATCGATCTGATCACGTCC
GATCGCCTCGGGCTACCTGGCCTGCCGGGCCGGCGCTGCGTGGGCCTCTACGCACTCGACGTGCAGACGGGCCGGACAGT
GACGATCGAGGCGCCGCACACGGTGCTCGCGACGGGCGGCGCGGGCAAGGTGTATCTGTACACGACGAACCCGGACACGG
CGACGGGCGACGGCATCGCGATGGCGTGGCGCGCGGGCGCGCGCGTCGCGAACATGGAGTTCATCCAGTTCCATCCGACG
TGCCTGTTCCATCCGTACGCGAAGTCGTTCCTCATTTCCGAGGCCGTGCGCGGCGAAGGCGGCCTGCTCAAGCTGCCGGA
CGGCACCCGCTTCATGCCCGCGCACGATCCGCGCGCGGAACTCGCGCCGCGCGACATCGTCGCGCGCGCGATCGACTTCG
AGATCAAGAAGCGCGGGATCGATTGCGTATATCTCGACATCAGCCATCAGCCCGAGGCATTCCTGCGCGAGCATTTCCCG
ACGATCTACGCGCGCTGCCTCGAGTTCGGCATCGACATCTCGAAGGAGCCGATCCCGGTCGTGCCGGCCGCGCACTACAC
GTGCGGCGGCGTCGTCACTGATCTGGCCGGGCGCACCGATATCGCGGGCCTGTACGCAGTCGGCGAGACGTCGTACACGG
GCCTGCACGGCGCGAACCGTCTCGCGAGCAATTCGCTGCTCGAATGCCTCGTGATCGGCCGCGCGACCGCCGAGTCGATC
GAAGCCGCCGGCTACGATTCGGCGACGCACGGCCCGCTGCCCGCATGGGACGAGAGCCGCGTCGCGGACGCCGACGAGGA
GGTGGTCGTCGCGCACAACTGGGACGAACTGCGCCGCCTGATGTGGAACTACGTCGGCATCGTGCGCACCGACAAGCGCC
TCGAGCGCGCGCAGCATCGGCTCAAGCTGCTGCGCGACGAGATCCACGAGTATTACGCGCACTTCCGCGTGAGCCGCGAT
CTGCTCGAGTTGCGCAATCTCGTGGACGTCGCGTCGCTGATCGTCGACGGCGCGCGGGCACGCCACGAAAGCCGCGGGCT
GCACTACAGCCGCGACTGGCCGCACGCATTGCCGAAGGCGCTGCCGACCGTGCTCACGCCGTCGCGGCGCATGCCGAAGT
AA

Upstream 100 bases:

>100_bases
GGCACGCAAGCGTTTCTCCGACGCGGTATGCTCTGCCCTTTCCGCCGCATTGCGCATGGCGGAAAAGATAAGACAAAACG
CGCAAGAAACGGAGATGCAG

Downstream 100 bases:

>100_bases
CGACGGCCGGCCGTGCGGCATGCCTCGCATCCGCGCGCGATACGCGACAAAAAAGGCCGCCCGCGCGTCAAGCGCCGGCG
GCCTCGCCTTTGGCTCATGC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSVENHVNDTLIAGGGLCDEAATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARTHPNITFFEDHHAIDLITS
DRLGLPGLPGRRCVGLYALDVQTGRTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGARVANMEFIQFHPT
CLFHPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFP
TIYARCLEFGIDISKEPIPVVPAAHYTCGGVVTDLAGRTDIAGLYAVGETSYTGLHGANRLASNSLLECLVIGRATAESI
EAAGYDSATHGPLPAWDESRVADADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAQHRLKLLRDEIHEYYAHFRVSRD
LLELRNLVDVASLIVDGARARHESRGLHYSRDWPHALPKALPTVLTPSRRMPK

Sequences:

>Translated_533_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSVENHVNDTLIAGGGLCDEAATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARTHPNITFFEDHHAIDLITS
DRLGLPGLPGRRCVGLYALDVQTGRTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGARVANMEFIQFHPT
CLFHPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFP
TIYARCLEFGIDISKEPIPVVPAAHYTCGGVVTDLAGRTDIAGLYAVGETSYTGLHGANRLASNSLLECLVIGRATAESI
EAAGYDSATHGPLPAWDESRVADADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAQHRLKLLRDEIHEYYAHFRVSRD
LLELRNLVDVASLIVDGARARHESRGLHYSRDWPHALPKALPTVLTPSRRMPK
>Mature_533_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSVENHVNDTLIAGGGLCDEAATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARTHPNITFFEDHHAIDLITS
DRLGLPGLPGRRCVGLYALDVQTGRTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGARVANMEFIQFHPT
CLFHPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFP
TIYARCLEFGIDISKEPIPVVPAAHYTCGGVVTDLAGRTDIAGLYAVGETSYTGLHGANRLASNSLLECLVIGRATAESI
EAAGYDSATHGPLPAWDESRVADADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAQHRLKLLRDEIHEYYAHFRVSRD
LLELRNLVDVASLIVDGARARHESRGLHYSRDWPHALPKALPTVLTPSRRMPK

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=509, Percent_Identity=34.9705304518664, Blast_Score=241, Evalue=1e-63,
Organism=Escherichia coli, GI1788928, Length=526, Percent_Identity=59.8859315589354, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1790597, Length=526, Percent_Identity=36.3117870722433, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1786942, Length=553, Percent_Identity=34.3580470162749, Blast_Score=228, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17550100, Length=531, Percent_Identity=34.2749529190207, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17505833, Length=528, Percent_Identity=32.7651515151515, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71986328, Length=478, Percent_Identity=28.6610878661088, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322701, Length=529, Percent_Identity=33.4593572778828, Blast_Score=238, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6322416, Length=512, Percent_Identity=33.59375, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6320788, Length=479, Percent_Identity=27.1398747390397, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322511, Length=478, Percent_Identity=26.9874476987448, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17137288, Length=539, Percent_Identity=33.5807050092764, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655642, Length=539, Percent_Identity=33.5807050092764, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655647, Length=539, Percent_Identity=33.5807050092764, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24663005, Length=555, Percent_Identity=32.6126126126126, Blast_Score=225, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 58333; Mature: 58333

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSVENH
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHH
VNDTLIAGGGLCDEAATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARTHPNITFFEDHHAIDLITSDRLGLPGLPGRRCVGLYALD
EEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEEE
VQTGRTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGARVANMEFIQFHPT
ECCCCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCEEECEEEEEECCC
CLFHPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGI
EEECHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCC
DCVYLDISHQPEAFLREHFPTIYARCLEFGIDISKEPIPVVPAAHYTCGGVVTDLAGRTD
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
IAGLYAVGETSYTGLHGANRLASNSLLECLVIGRATAESIEAAGYDSATHGPLPAWDESR
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCC
VADADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAQHRLKLLRDEIHEYYAHFRVSRD
CCCCCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLELRNLVDVASLIVDGARARHESRGLHYSRDWPHALPKALPTVLTPSRRMPK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSVENH
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHH
VNDTLIAGGGLCDEAATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARTHPNITFFEDHHAIDLITSDRLGLPGLPGRRCVGLYALD
EEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEEE
VQTGRTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGARVANMEFIQFHPT
ECCCCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCEEECEEEEEECCC
CLFHPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGI
EEECHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCC
DCVYLDISHQPEAFLREHFPTIYARCLEFGIDISKEPIPVVPAAHYTCGGVVTDLAGRTD
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
IAGLYAVGETSYTGLHGANRLASNSLLECLVIGRATAESIEAAGYDSATHGPLPAWDESR
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCC
VADADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAQHRLKLLRDEIHEYYAHFRVSRD
CCCCCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLELRNLVDVASLIVDGARARHESRGLHYSRDWPHALPKALPTVLTPSRRMPK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]