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The map label for this gene is lolB [H]

Identifier: 83719560

GI number: 83719560

Start: 529427

End: 530056

Strand: Reverse

Name: lolB [H]

Synonym: BTH_I0477

Alternate gene names: 83719560

Gene position: 530056-529427 (Counterclockwise)

Preceding gene: 83720331

Following gene: 83719126

Centisome position: 13.92

GC content: 70.95

Gene sequence:

>630_bases
ATGACGATGCCGCGCTTTGCCTGGCCGCATGCGCGCACCGCGCGCCGCGTCGCCTTCGCAGCCGCAGCCGCAGCCGCCGT
CGCGCTCGCCGGCTGCGCGACGCAGCCGCAGCGCGCGCCCATCGCCGCGCCGAGCGCGCTGCAGACCGAGCAGAATCGCG
CGTACACAGGCCGCTTCGCGGTCCAGTACCACGATCAGCTCGGCAATCCGCGCAACGTCTACGGCAATTTCGATTGGCAG
GAGCAAGGCACGAACGTGTCGCTCGAGCTGCGCAGCCCGCTCGGCCAGACGCTCGCGATCGTGAAGTCGGCGCCGGACGG
CGCGTCGCTCGAACTGCCGAACCGTCAACCGCAATTCGCGCCCGACGTCGGCGAGCTGATGCAGCGCTCGCTTGGCTTCG
CACTGCCCCTCGACGGCCTGCGCTACTGGCTGCTGCCGACGCCGTCGCCCGCGACGCCCGCGACGACGGTGCGCGATCCG
CAGGACGGCGCGCGAATCAAGGAGATCCGCCAGGACGGCTGGACCATCGATTACGTCGCGTACGCCGATGCGCCCGCCGC
CGCCGTGAAACGCGTCAACCTGGTGCGGCAGACGCCGCCCCTCGACATCAAGCTTGTGCTCGACCGCTGA

Upstream 100 bases:

>100_bases
GCGACGAAGCGCGCGCCGCATGGCGCGCCGCGCAGAAGCTCGAGCCCGATAACGACACGCTCGTGCAGACGCTCAAGCGC
TTTCAGGTGAACGGACTGTG

Downstream 100 bases:

>100_bases
GCACGCGCCTGCGCCCGATCAAATTTCCTCAGCATGACCGATACGACCCGCTCGCTGCGCGACTGCCTCGCCCCGGCGAA
ACTGAACCTGTTCCTGCACA

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTMPRFAWPHARTARRVAFAAAAAAAVALAGCATQPQRAPIAAPSALQTEQNRAYTGRFAVQYHDQLGNPRNVYGNFDWQ
EQGTNVSLELRSPLGQTLAIVKSAPDGASLELPNRQPQFAPDVGELMQRSLGFALPLDGLRYWLLPTPSPATPATTVRDP
QDGARIKEIRQDGWTIDYVAYADAPAAAVKRVNLVRQTPPLDIKLVLDR

Sequences:

>Translated_209_residues
MTMPRFAWPHARTARRVAFAAAAAAAVALAGCATQPQRAPIAAPSALQTEQNRAYTGRFAVQYHDQLGNPRNVYGNFDWQ
EQGTNVSLELRSPLGQTLAIVKSAPDGASLELPNRQPQFAPDVGELMQRSLGFALPLDGLRYWLLPTPSPATPATTVRDP
QDGARIKEIRQDGWTIDYVAYADAPAAAVKRVNLVRQTPPLDIKLVLDR
>Mature_208_residues
TMPRFAWPHARTARRVAFAAAAAAAVALAGCATQPQRAPIAAPSALQTEQNRAYTGRFAVQYHDQLGNPRNVYGNFDWQE
QGTNVSLELRSPLGQTLAIVKSAPDGASLELPNRQPQFAPDVGELMQRSLGFALPLDGLRYWLLPTPSPATPATTVRDPQ
DGARIKEIRQDGWTIDYVAYADAPAAAVKRVNLVRQTPPLDIKLVLDR

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 22795; Mature: 22664

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPRFAWPHARTARRVAFAAAAAAAVALAGCATQPQRAPIAAPSALQTEQNRAYTGRFA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCEEEEEEE
VQYHDQLGNPRNVYGNFDWQEQGTNVSLELRSPLGQTLAIVKSAPDGASLELPNRQPQFA
EEEHHHCCCCCEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCEEECCCCCCCCC
PDVGELMQRSLGFALPLDGLRYWLLPTPSPATPATTVRDPQDGARIKEIRQDGWTIDYVA
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
YADAPAAAVKRVNLVRQTPPLDIKLVLDR
ECCCHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
TMPRFAWPHARTARRVAFAAAAAAAVALAGCATQPQRAPIAAPSALQTEQNRAYTGRFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCEEEEEEE
VQYHDQLGNPRNVYGNFDWQEQGTNVSLELRSPLGQTLAIVKSAPDGASLELPNRQPQFA
EEEHHHCCCCCEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCEEECCCCCCCCC
PDVGELMQRSLGFALPLDGLRYWLLPTPSPATPATTVRDPQDGARIKEIRQDGWTIDYVA
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
YADAPAAAVKRVNLVRQTPPLDIKLVLDR
ECCCHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA