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The map label for this gene is gcvT [H]

Identifier: 83719545

GI number: 83719545

Start: 3713954

End: 3715708

Strand: Reverse

Name: gcvT [H]

Synonym: BTH_I3255

Alternate gene names: 83719545

Gene position: 3715708-3713954 (Counterclockwise)

Preceding gene: 83719625

Following gene: 83721648

Centisome position: 97.55

GC content: 68.6

Gene sequence:

>1755_bases
GTGAGCGCGCGGCGGCCCCACGAACTTCCGGGGCCGCCCGGCCGACGATGCCTCGGCGCGCGGCTTCGGCGCCTTTTTCG
CGCAAGCCGCGCGCGCCGACGAAACGCTTCACGATTCCGACCCCGGCACGCTCACCGCTCACCGCTCACCGAATCATCCG
CAGCCCGCGCCGCCAACGCCCGGCGTCCGCCGCCGCTTGTCTTCAAGCGACAGCGATTTGCCCAAATTGACAACCCATCC
GCGCTCGCGTACATTCGCCCGCACGCGTCGGGAGAGCGTGCGGCCGCCATTCGTTGTCGATCGAAAGGCAAGCCGCGCCG
CCGAAGGGGCACACCCGCAAACTCTCAGGCAAAAGGACCGACCGCGTCGAAGAATCCGTCTGACGACATGCGTCGGGCGA
CGTTTTTCGCACTCTGGAGAGCGGCAGTAGCCGCGTGCGCGCAACGCGACGCACGGGCAGGCTGCCCACCGAAGGGGCGC
GCGCGAGCCGGATCGAATCCGCCGCGCAATCTCTCAGGTATCGAGGACAGAGGGGCATGCACGCATCGCAGGCGGCTTCA
CGCGCCGGCGGTTCGCCGAGTTGCCGTTTTGTTTTCGCGCCCGGGCCAAGTCCCGGCCGCCTTGCCTGGGACCCCGATGA
CCGTTCTCAAAATCACCCCGCTTCACGCCGCGCATCGCGCCCTCAACGCCCGCATGGTCGATTTCGGCGGCTGGGACATG
CCCGTCAACTACGGCTCGCAGATCGAAGAGCACCAGGCGGTGCGTACCGATGCCGGCATGTTCGACGTGTCGCACATGTG
TGTCGTCGATTTCACGGGCCCGCGCGTGCGTGCGTTCTTCGAGCACGCGCTCGCGAACAACGTCGCGAAGCTGCAAACGC
CCGGCAAGGCGCTCTATTCGTGCCTGCTGAACCCGCAAGGCGGCGTCATCGACGATCTGATCGTCTACTACTTCACCGAG
GATTTCTTCCGCGTCGTCGTCAACGCCGGCACGGCCGACAAGGACGTCGCGTGGTTCAGCCAGCTCAACGAGCAAGGCGG
CTTCGGCCTCACGATCGCGCCGCGCCGCGACTTCGCGATCGTCGCCGTCCAGGGGCCGAACGCGCGCGCGAAGGTGTGGG
ACACCGTGCCCGCCGCGCGCGCCGCGACGAGCGAGCTCAAGCCCTTCAACGCCGCGCAGGTCGCAGGCACGCCGTTCGGC
GACCTCACCGTCGCGCGCACCGGCTACACGGGCGAGGACGGCTTCGAGATCATCGTCCCGGCGATGCACGTCGAAGCGCT
GTGGAACGCGCTCGCCGAACGCGGCGTGCGCCCGTGCGGGCTCGGCGCACGCGACACGCTGCGCCTCGAGGCCGGCATGA
ATCTCTACGGCCAGGACATGGACGAAACGGTATCGCCGCTCGACGCCGGTCTCGCGTGGACGGTCGATCTCGCCGCGCCG
CGCGCGTTCGTCGGCCGCGACGCGCTCGAAGCGAACGGCTCGCGCGCGGCATTCGTCGGCCTCATCCTGCAGAAGGAGAA
CGGCCGCGCGGGTGGCGTGCTGCGCGCGCACCAGAAGGTCGTGACGCCGCACGGCGACGGCGAGATCACGAGCGGCACGT
TCTCGCCGACGATGCAGGAATCGATCGCGTTCGCACGCGTGCCGAAGGGCGTCGCCATCGGCGACACGGTGCACGTGCAG
ATCCGCGACAAGAATCTTCCCGCGCGCGTGGTAAAACTGCCGTTCGTGCGCAACGGCAAGGTCCTCGCTGCGTAA

Upstream 100 bases:

>100_bases
AATCGACCGACATGGCGGCCCAGCACGGCGGCGGCCTGTCCGGCGACGAGCAGCGCGTACTCAATCAGGAGCTCGACGTG
GCCGCACGCGCGATCGGCGA

Downstream 100 bases:

>100_bases
CGGGCCGGGCGGCGCGCCGCCCGGCGATACCGCACCCGGCGCGCCCATTGCGCGCCAGAAAGAATCACACCCTTTTCCAT
TCAGGAGCATTCGATGAGCA

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSARRPHELPGPPGRRCLGARLRRLFRASRARRRNASRFRPRHAHRSPLTESSAARAANARRPPPLVFKRQRFAQIDNPS
ALAYIRPHASGERAAAIRCRSKGKPRRRRGTPANSQAKGPTASKNPSDDMRRATFFALWRAAVAACAQRDARAGCPPKGR
ARAGSNPPRNLSGIEDRGACTHRRRLHAPAVRRVAVLFSRPGQVPAALPGTPMTVLKITPLHAAHRALNARMVDFGGWDM
PVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHALANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTE
DFFRVVVNAGTADKDVAWFSQLNEQGGFGLTIAPRRDFAIVAVQGPNARAKVWDTVPAARAATSELKPFNAAQVAGTPFG
DLTVARTGYTGEDGFEIIVPAMHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDETVSPLDAGLAWTVDLAAP
RAFVGRDALEANGSRAAFVGLILQKENGRAGGVLRAHQKVVTPHGDGEITSGTFSPTMQESIAFARVPKGVAIGDTVHVQ
IRDKNLPARVVKLPFVRNGKVLAA

Sequences:

>Translated_584_residues
MSARRPHELPGPPGRRCLGARLRRLFRASRARRRNASRFRPRHAHRSPLTESSAARAANARRPPPLVFKRQRFAQIDNPS
ALAYIRPHASGERAAAIRCRSKGKPRRRRGTPANSQAKGPTASKNPSDDMRRATFFALWRAAVAACAQRDARAGCPPKGR
ARAGSNPPRNLSGIEDRGACTHRRRLHAPAVRRVAVLFSRPGQVPAALPGTPMTVLKITPLHAAHRALNARMVDFGGWDM
PVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHALANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTE
DFFRVVVNAGTADKDVAWFSQLNEQGGFGLTIAPRRDFAIVAVQGPNARAKVWDTVPAARAATSELKPFNAAQVAGTPFG
DLTVARTGYTGEDGFEIIVPAMHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDETVSPLDAGLAWTVDLAAP
RAFVGRDALEANGSRAAFVGLILQKENGRAGGVLRAHQKVVTPHGDGEITSGTFSPTMQESIAFARVPKGVAIGDTVHVQ
IRDKNLPARVVKLPFVRNGKVLAA
>Mature_583_residues
SARRPHELPGPPGRRCLGARLRRLFRASRARRRNASRFRPRHAHRSPLTESSAARAANARRPPPLVFKRQRFAQIDNPSA
LAYIRPHASGERAAAIRCRSKGKPRRRRGTPANSQAKGPTASKNPSDDMRRATFFALWRAAVAACAQRDARAGCPPKGRA
RAGSNPPRNLSGIEDRGACTHRRRLHAPAVRRVAVLFSRPGQVPAALPGTPMTVLKITPLHAAHRALNARMVDFGGWDMP
VNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHALANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTED
FFRVVVNAGTADKDVAWFSQLNEQGGFGLTIAPRRDFAIVAVQGPNARAKVWDTVPAARAATSELKPFNAAQVAGTPFGD
LTVARTGYTGEDGFEIIVPAMHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDETVSPLDAGLAWTVDLAAPR
AFVGRDALEANGSRAAFVGLILQKENGRAGGVLRAHQKVVTPHGDGEITSGTFSPTMQESIAFARVPKGVAIGDTVHVQI
RDKNLPARVVKLPFVRNGKVLAA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=380, Percent_Identity=36.0526315789474, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI257796258, Length=351, Percent_Identity=36.1823361823362, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI257796254, Length=375, Percent_Identity=32.2666666666667, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI257796256, Length=315, Percent_Identity=35.5555555555556, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI24797151, Length=341, Percent_Identity=29.0322580645161, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI197927446, Length=347, Percent_Identity=25.0720461095101, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI21361378, Length=347, Percent_Identity=25.0720461095101, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1789272, Length=374, Percent_Identity=55.3475935828877, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17560118, Length=386, Percent_Identity=34.7150259067358, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71994045, Length=369, Percent_Identity=22.4932249322493, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994052, Length=369, Percent_Identity=22.4932249322493, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320222, Length=386, Percent_Identity=35.4922279792746, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI20129441, Length=379, Percent_Identity=33.7730870712401, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI20130091, Length=306, Percent_Identity=25.1633986928105, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 63295; Mature: 63164

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRPHELPGPPGRRCLGARLRRLFRASRARRRNASRFRPRHAHRSPLTESSAARAANA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHCC
RRPPPLVFKRQRFAQIDNPSALAYIRPHASGERAAAIRCRSKGKPRRRRGTPANSQAKGP
CCCCCHHCCHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCC
TASKNPSDDMRRATFFALWRAAVAACAQRDARAGCPPKGRARAGSNPPRNLSGIEDRGAC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
THRRRLHAPAVRRVAVLFSRPGQVPAALPGTPMTVLKITPLHAAHRALNARMVDFGGWDM
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCEEEECCCCCC
PVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHALANNVAKLQTPGKALYS
CCCCCCHHHHHHHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHCCHHHHCCCHHHHHH
CLLNPQGGVIDDLIVYYFTEDFFRVVVNAGTADKDVAWFSQLNEQGGFGLTIAPRRDFAI
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEE
VAVQGPNARAKVWDTVPAARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVP
EEEECCCCCCEEECCCCHHHHHHHHCCCCCCHHCCCCCCCCEEEEECCCCCCCCCEEEEH
AMHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDETVSPLDAGLAWTVDLAAP
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCC
RAFVGRDALEANGSRAAFVGLILQKENGRAGGVLRAHQKVVTPHGDGEITSGTFSPTMQE
HHHHCCHHHHCCCCCEEEEEEEEECCCCCCCCEEEECCEEECCCCCCCCCCCCCCCHHHH
SIAFARVPKGVAIGDTVHVQIRDKNLPARVVKLPFVRNGKVLAA
HHHHHHCCCCCEECCEEEEEEECCCCCEEEEECCEEECCCEEEC
>Mature Secondary Structure 
SARRPHELPGPPGRRCLGARLRRLFRASRARRRNASRFRPRHAHRSPLTESSAARAANA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHCC
RRPPPLVFKRQRFAQIDNPSALAYIRPHASGERAAAIRCRSKGKPRRRRGTPANSQAKGP
CCCCCHHCCHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCC
TASKNPSDDMRRATFFALWRAAVAACAQRDARAGCPPKGRARAGSNPPRNLSGIEDRGAC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
THRRRLHAPAVRRVAVLFSRPGQVPAALPGTPMTVLKITPLHAAHRALNARMVDFGGWDM
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCEEEECCCCCC
PVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHALANNVAKLQTPGKALYS
CCCCCCHHHHHHHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHCCHHHHCCCHHHHHH
CLLNPQGGVIDDLIVYYFTEDFFRVVVNAGTADKDVAWFSQLNEQGGFGLTIAPRRDFAI
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEE
VAVQGPNARAKVWDTVPAARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVP
EEEECCCCCCEEECCCCHHHHHHHHCCCCCCHHCCCCCCCCEEEEECCCCCCCCCEEEEH
AMHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDETVSPLDAGLAWTVDLAAP
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCC
RAFVGRDALEANGSRAAFVGLILQKENGRAGGVLRAHQKVVTPHGDGEITSGTFSPTMQE
HHHHCCHHHHCCCCCEEEEEEEEECCCCCCCCEEEECCEEECCCCCCCCCCCCCCCHHHH
SIAFARVPKGVAIGDTVHVQIRDKNLPARVVKLPFVRNGKVLAA
HHHHHHCCCCCEECCEEEEEEECCCCCEEEEECCEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA