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The map label for this gene is lolC [H]

Identifier: 83719509

GI number: 83719509

Start: 2133339

End: 2134685

Strand: Direct

Name: lolC [H]

Synonym: BTH_I1887

Alternate gene names: 83719509

Gene position: 2133339-2134685 (Clockwise)

Preceding gene: 83718832

Following gene: 83718639

Centisome position: 56.0

GC content: 66.67

Gene sequence:

>1347_bases
GTGTGGCACACTGCGCGCGTAACCGGGTCGGCCCGGCTTGCGGCGCGCGGATTCGCGCAGCGCGCGGCGTCCCAACCAGC
AGAAAGGATACGCTTGAAACTTCCGTACGAATGGCAGATCGGCTGGCGCTATACGCGCGCCGGCAAACGCACGACCGGCA
ACGGCTTCATTTCCTTCATCGCGCTCGTGTCGATGCTCGGGATCGCGCTCGGCGTCGCGGCGCTCATCGTCGTGCTGTCG
GTGATGAACGGCTTTCAGAAGGAGGTGCGCGACCGGATGCTGTCGGTGCTCGCGCACGTCGAGATTTTCTCGCCGACGGG
CTCGATGCCCGACTGGCAACTGACCGCGAAGGAAGCGCGCCTGAATCGATCGGTGATCGGCGCGGCGCCGTACGTCGACG
CGCAGGCGCTTCTCACGCGGCAGGACGCGGTGAGCGGCGTGATGCTGCGCGGCGTCGAGCCGTCGCTCGAGCCGCAGGTG
TCCGACATCGGCAAGGACATGAAGGCGGGCGCGCTCACGGCGCTCGCGCCCGGCCAGTTCGGGATCGTGCTCGGCAACGC
GCTCGCGGGCAATCTCGGGGTGGGCGTCGGCGACAAGGTCACGCTCGTCGCGCCGGAGGGCACGATCACGCCGGCCGGGA
TGATGCCGCGCCTGAAGCAGTTCACCGTGGTCGGCATCTTCGAGTCCGGCCATTACGAATACGACAGCACGCTTGCGATG
ATCGACATCCAGGACGCGCAGGCGCTCTTCAGGCTGCCCGCGCCGACGGGCGTGCGGCTGCGTCTCACGGACATGCAGAA
GGCGCCGCAGGTCGCGCGCGAACTCGCGCACACGCTGTCGGGCGACCTGTATATCCGCGACTGGACGCAGCAGAACAAGA
CGTGGTTCTCCGCAGTGCAGATCGAGAAGCGGATGATGTTCATCATCCTCACGCTGATCATCGCGGTCGCGGCGTTCAAC
CTCGTATCGTCGCTCGTGATGACGGTGACGAACAAGCAGGCGGACATCGCGATCCTGCGCACGCTCGGCGCGCAGCCGGG
CTCCATCATGAAGATCTTCGTCGTGCAGGGCGTGACGATCGGCTTCGTCGGCACCGCGACGGGCGTCGCGCTCGGCTGCC
TGATCGCGTGGAGCATTCCGTGGCTCATTCCGATGATCGAGCATGCGTTCGGCGTGCAGTTCCTGCCGCCGTCGGTGTAC
TTCATCAGCGAGCTGCCGTCCGAGCTCGTCGCGGGCGACGTGATCAAGATCGGCGTGATCGCTTTCGTGCTGTCCGCGCT
CGCGACGCTCTATCCGAGCTGGCGCGGCGCGAAGGTGCGACCGGCGGAGGCGCTGCGCTATGAATGA

Upstream 100 bases:

>100_bases
GCGGAGTCGACCGGGCGCGCAGCGATGCGGCGCGCGTCGCCCGAACTCGTGCGGCGCGCGTATCGCCGATCCGGAGCGTT
TTCAGGGCCGATTAAGCATT

Downstream 100 bases:

>100_bases
CCGGGTTTTCGAACAGACGATGAATCAGAACCATCAGGGTGGCGCCGCGCGCGAATGCGTGCTCGAGGCGCACGGCATCA
CGAAGACGTTCATGCAGGGC

Product: lipoprotein releasing system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MWHTARVTGSARLAARGFAQRAASQPAERIRLKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLS
VMNGFQKEVRDRMLSVLAHVEIFSPTGSMPDWQLTAKEARLNRSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQV
SDIGKDMKAGALTALAPGQFGIVLGNALAGNLGVGVGDKVTLVAPEGTITPAGMMPRLKQFTVVGIFESGHYEYDSTLAM
IDIQDAQALFRLPAPTGVRLRLTDMQKAPQVARELAHTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFN
LVSSLVMTVTNKQADIAILRTLGAQPGSIMKIFVVQGVTIGFVGTATGVALGCLIAWSIPWLIPMIEHAFGVQFLPPSVY
FISELPSELVAGDVIKIGVIAFVLSALATLYPSWRGAKVRPAEALRYE

Sequences:

>Translated_448_residues
MWHTARVTGSARLAARGFAQRAASQPAERIRLKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLS
VMNGFQKEVRDRMLSVLAHVEIFSPTGSMPDWQLTAKEARLNRSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQV
SDIGKDMKAGALTALAPGQFGIVLGNALAGNLGVGVGDKVTLVAPEGTITPAGMMPRLKQFTVVGIFESGHYEYDSTLAM
IDIQDAQALFRLPAPTGVRLRLTDMQKAPQVARELAHTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFN
LVSSLVMTVTNKQADIAILRTLGAQPGSIMKIFVVQGVTIGFVGTATGVALGCLIAWSIPWLIPMIEHAFGVQFLPPSVY
FISELPSELVAGDVIKIGVIAFVLSALATLYPSWRGAKVRPAEALRYE
>Mature_448_residues
MWHTARVTGSARLAARGFAQRAASQPAERIRLKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLS
VMNGFQKEVRDRMLSVLAHVEIFSPTGSMPDWQLTAKEARLNRSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQV
SDIGKDMKAGALTALAPGQFGIVLGNALAGNLGVGVGDKVTLVAPEGTITPAGMMPRLKQFTVVGIFESGHYEYDSTLAM
IDIQDAQALFRLPAPTGVRLRLTDMQKAPQVARELAHTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFN
LVSSLVMTVTNKQADIAILRTLGAQPGSIMKIFVVQGVTIGFVGTATGVALGCLIAWSIPWLIPMIEHAFGVQFLPPSVY
FISELPSELVAGDVIKIGVIAFVLSALATLYPSWRGAKVRPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=34.1346153846154, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=36.319612590799, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48432; Mature: 48432

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWHTARVTGSARLAARGFAQRAASQPAERIRLKLPYEWQIGWRYTRAGKRTTGNGFISFI
CCCEEEECCCHHHHHHHHHHHHHCCCHHHEEEECCEEEEECEEEECCCCCCCCCHHHHHH
ALVSMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEIFSPTGSMPDWQLTAKEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEHHHHH
LNRSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQVSDIGKDMKAGALTALAPGQF
HCHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHCCHHHCCCEEEECCCCE
GIVLGNALAGNLGVGVGDKVTLVAPEGTITPAGMMPRLKQFTVVGIFESGHYEYDSTLAM
EEEECCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHEEEEEEEECCCEECCCEEEE
IDIQDAQALFRLPAPTGVRLRLTDMQKAPQVARELAHTLSGDLYIRDWTQQNKTWFSAVQ
EEECCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
IEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMKIFVVQGVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCCEE
GFVGTATGVALGCLIAWSIPWLIPMIEHAFGVQFLPPSVYFISELPSELVAGDVIKIGVI
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHCCHHHHHCCHHHHHHH
AFVLSALATLYPSWRGAKVRPAEALRYE
HHHHHHHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MWHTARVTGSARLAARGFAQRAASQPAERIRLKLPYEWQIGWRYTRAGKRTTGNGFISFI
CCCEEEECCCHHHHHHHHHHHHHCCCHHHEEEECCEEEEECEEEECCCCCCCCCHHHHHH
ALVSMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEIFSPTGSMPDWQLTAKEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEHHHHH
LNRSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQVSDIGKDMKAGALTALAPGQF
HCHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHCCHHHCCCEEEECCCCE
GIVLGNALAGNLGVGVGDKVTLVAPEGTITPAGMMPRLKQFTVVGIFESGHYEYDSTLAM
EEEECCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHEEEEEEEECCCEECCCEEEE
IDIQDAQALFRLPAPTGVRLRLTDMQKAPQVARELAHTLSGDLYIRDWTQQNKTWFSAVQ
EEECCCHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
IEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMKIFVVQGVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCCEE
GFVGTATGVALGCLIAWSIPWLIPMIEHAFGVQFLPPSVYFISELPSELVAGDVIKIGVI
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHCCHHHHHCCHHHHHHH
AFVLSALATLYPSWRGAKVRPAEALRYE
HHHHHHHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]