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The map label for this gene is hpmB [H]

Identifier: 83719499

GI number: 83719499

Start: 3119693

End: 3121429

Strand: Reverse

Name: hpmB [H]

Synonym: BTH_I2721

Alternate gene names: 83719499

Gene position: 3121429-3119693 (Counterclockwise)

Preceding gene: 83718793

Following gene: 83719658

Centisome position: 81.94

GC content: 60.91

Gene sequence:

>1737_bases
ATGACAATCCGTACCCCGGTCGTGCTGCTGTCGGCCGCATGGCTGATTCCAATGGCCGTGTCGGCGCAAGAAGCTCCTCG
CCCGATCATTTCGGGCAACGACCAGCAAATCCGACAGCAGGAAGAAGCGCGCGAGCGCGAACGGACCGTCACAGCGCCCG
GGGTGCGTTCGAGCGTAACGGCGAGCGCAGGGTATCCAGCGCTGCCATCCGAAACGCCGTGCTTTCGCATTGACCGTTTT
GGGCTCGACGTACCCGATGCGCTGCCTACCTCGCTGAAATCGCAAGGCGCGTCGGCGTTGCCCATGGATCGCTTCGCCTT
CGCGCGTGAATGGCTTGAGCACTATGCTGGCCAGTGCATCGGAAAACAGGGCCTCGACATCCTCGTCAAGGGTCTGTCGC
AAGCGATCCTAGCGCGCGGGTACGTCACGACGCGTGTACTACTTCCTGAACAGGATCTGTCGACCGGTATCCTCAAGTTT
TCGCTGATCCCGGGTGTGGTCCGCCACGTGCGCTTCGCCGACGAGAAACTGCGCGGCACGTGGAAGACCGCATTTCCAAC
GGGCGACGGCGAACTGCTGAACCTGCGCGATCTCGAACAGGGCCTCGAGCAAATGAAACGCGTGTCGAGCCAGGACGTTT
CGATGCAAATCGTTCCGGGCGAGCTTCCCGGCGAAAGCGATGTCGTACTCGACGTGAAGCGAGGCAAACCGTGGACCGTC
GTCGCGTCCGTCGACAACTCCGGCACGCGTGCGACTGGCAAGCTGCAAGGCAATCTGTCGCTCGGCATCGACAATCCGCT
CGGCCTGAACGACGTCTTCAACATCGGCGTCAGCCAGGATCTGGAGTTTGGGGACAAGCGCCTCGGCTCGCACGGCTGGA
ACGGTTTCTATTCGATTCCGTGGGGTTACTGGACGGCCACGCTGTCCGCTTACACGAACACGTACTACCAGCAGATTGCT
GGCGTGAATCAGACATTCGTCGCGAGCGGCAATTCAAAGACGGTCGATTTCAAGCTGGCCCGCGTGCTGTCGCGTAGTCA
GAATGATGTGTTCGGTGGGTACGTTCGCCTGTCGCGTCGTTTCGGGCAAAGCTTTATCGAAGACACCGAAATCTCGCAGC
AACGCCGCAATAACACGATGATCGAACTCGGCCTGACCGATCGCCACTACTTCGGCGGCGCGCAGTTCGATGGCTCACTT
GCATATCGTCAAGGCGTCGGTGGATTGGGCGCTCAGGACGATACGTTGGCGGCGGGTGGTGGGCCGACCTATCGTTTCAA
GATGGCGGTGCTCGATGCGAACCTGTCGGTGCCGTTCGCGATCGGCAAGCAGCCATTCCGCTATGTCGGCACATTCCACG
GCCAGTACACCGGAAACACGCTGTACTACATCGACGACTTGACGATTGGCAGTCGGTATACAGTACGCGGTTTCGACGGC
GAGACGATGCTGGCGGCGGCACGTGGCTTTTACTGGCGCAACGAGCTACAGGCGCCGATTGGGCAGATGGGGCAGGCGCT
CTATGCGGGGCTCGATTATGGCCGCGTATGGGGGCCGCAGCCGATCGCACTCGTCGGCACGCAACTGGCGGGTGCTGTGA
TCGGCGTGAAGGGGAGTGTCGGCACGCGATTCGGCTCCTATGCGTACGATCTCTTCGCGGGTACGCCTGTCTACAAGCCG
TCAGGTTTTCCGACGGCACGTGTGACGCTCGGTTTTCAGGTGACCGCTCAGTTCTGA

Upstream 100 bases:

>100_bases
CTGGATCATGGGCTTTTGGAAATGGAGCGGTACCGAATGGGTTTGGATTCCGGGGCATTTAGCACCCAAGCCATAAAATC
GAACGAACAAGACCACATTT

Downstream 100 bases:

>100_bases
AGACAATGAGCCAAGGTACTTCTCCGACACGTATACATCGCAAGCCCGATGTTGCATATGCTCGTCTGGTCGAGGCTGCC
GCTGAACGGGGGCGTACGCT

Product: outer membrane hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MTIRTPVVLLSAAWLIPMAVSAQEAPRPIISGNDQQIRQQEEARERERTVTAPGVRSSVTASAGYPALPSETPCFRIDRF
GLDVPDALPTSLKSQGASALPMDRFAFAREWLEHYAGQCIGKQGLDILVKGLSQAILARGYVTTRVLLPEQDLSTGILKF
SLIPGVVRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVSSQDVSMQIVPGELPGESDVVLDVKRGKPWTV
VASVDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIA
GVNQTFVASGNSKTVDFKLARVLSRSQNDVFGGYVRLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGAQFDGSL
AYRQGVGGLGAQDDTLAAGGGPTYRFKMAVLDANLSVPFAIGKQPFRYVGTFHGQYTGNTLYYIDDLTIGSRYTVRGFDG
ETMLAAARGFYWRNELQAPIGQMGQALYAGLDYGRVWGPQPIALVGTQLAGAVIGVKGSVGTRFGSYAYDLFAGTPVYKP
SGFPTARVTLGFQVTAQF

Sequences:

>Translated_578_residues
MTIRTPVVLLSAAWLIPMAVSAQEAPRPIISGNDQQIRQQEEARERERTVTAPGVRSSVTASAGYPALPSETPCFRIDRF
GLDVPDALPTSLKSQGASALPMDRFAFAREWLEHYAGQCIGKQGLDILVKGLSQAILARGYVTTRVLLPEQDLSTGILKF
SLIPGVVRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVSSQDVSMQIVPGELPGESDVVLDVKRGKPWTV
VASVDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIA
GVNQTFVASGNSKTVDFKLARVLSRSQNDVFGGYVRLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGAQFDGSL
AYRQGVGGLGAQDDTLAAGGGPTYRFKMAVLDANLSVPFAIGKQPFRYVGTFHGQYTGNTLYYIDDLTIGSRYTVRGFDG
ETMLAAARGFYWRNELQAPIGQMGQALYAGLDYGRVWGPQPIALVGTQLAGAVIGVKGSVGTRFGSYAYDLFAGTPVYKP
SGFPTARVTLGFQVTAQF
>Mature_577_residues
TIRTPVVLLSAAWLIPMAVSAQEAPRPIISGNDQQIRQQEEARERERTVTAPGVRSSVTASAGYPALPSETPCFRIDRFG
LDVPDALPTSLKSQGASALPMDRFAFAREWLEHYAGQCIGKQGLDILVKGLSQAILARGYVTTRVLLPEQDLSTGILKFS
LIPGVVRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVSSQDVSMQIVPGELPGESDVVLDVKRGKPWTVV
ASVDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAG
VNQTFVASGNSKTVDFKLARVLSRSQNDVFGGYVRLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGAQFDGSLA
YRQGVGGLGAQDDTLAAGGGPTYRFKMAVLDANLSVPFAIGKQPFRYVGTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGE
TMLAAARGFYWRNELQAPIGQMGQALYAGLDYGRVWGPQPIALVGTQLAGAVIGVKGSVGTRFGSYAYDLFAGTPVYKPS
GFPTARVTLGFQVTAQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62993; Mature: 62862

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRTPVVLLSAAWLIPMAVSAQEAPRPIISGNDQQIRQQEEARERERTVTAPGVRSSVT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCC
ASAGYPALPSETPCFRIDRFGLDVPDALPTSLKSQGASALPMDRFAFAREWLEHYAGQCI
CCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GKQGLDILVKGLSQAILARGYVTTRVLLPEQDLSTGILKFSLIPGVVRHVRFADEKLRGT
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
WKTAFPTGDGELLNLRDLEQGLEQMKRVSSQDVSMQIVPGELPGESDVVLDVKRGKPWTV
EEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCEEE
VASVDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLEFGDKRLGSHGWNGFYSIP
EEEECCCCCEEEEEEEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCEEECC
WGYWTATLSAYTNTYYQQIAGVNQTFVASGNSKTVDFKLARVLSRSQNDVFGGYVRLSRR
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHH
FGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGAQFDGSLAYRQGVGGLGAQDDTLAAGG
HHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHCCCCCCCCCCCEEECCC
GPTYRFKMAVLDANLSVPFAIGKQPFRYVGTFHGQYTGNTLYYIDDLTIGSRYTVRGFDG
CCCEEEEEEEEECCCCCCEEECCCCCEEHEEECCEECCCEEEEEEEEEECCEEEEECCCC
ETMLAAARGFYWRNELQAPIGQMGQALYAGLDYGRVWGPQPIALVGTQLAGAVIGVKGSV
CCHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCEEEEECCCC
GTRFGSYAYDLFAGTPVYKPSGFPTARVTLGFQVTAQF
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
TIRTPVVLLSAAWLIPMAVSAQEAPRPIISGNDQQIRQQEEARERERTVTAPGVRSSVT
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCC
ASAGYPALPSETPCFRIDRFGLDVPDALPTSLKSQGASALPMDRFAFAREWLEHYAGQCI
CCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GKQGLDILVKGLSQAILARGYVTTRVLLPEQDLSTGILKFSLIPGVVRHVRFADEKLRGT
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
WKTAFPTGDGELLNLRDLEQGLEQMKRVSSQDVSMQIVPGELPGESDVVLDVKRGKPWTV
EEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCEEE
VASVDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLEFGDKRLGSHGWNGFYSIP
EEEECCCCCEEEEEEEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCEEECC
WGYWTATLSAYTNTYYQQIAGVNQTFVASGNSKTVDFKLARVLSRSQNDVFGGYVRLSRR
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHH
FGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGAQFDGSLAYRQGVGGLGAQDDTLAAGG
HHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHCCCCCCCCCCCEEECCC
GPTYRFKMAVLDANLSVPFAIGKQPFRYVGTFHGQYTGNTLYYIDDLTIGSRYTVRGFDG
CCCEEEEEEEEECCCCCCEEECCCCCEEHEEECCEECCCEEEEEEEEEECCEEEEECCCC
ETMLAAARGFYWRNELQAPIGQMGQALYAGLDYGRVWGPQPIALVGTQLAGAVIGVKGSV
CCHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCEEEEECCCC
GTRFGSYAYDLFAGTPVYKPSGFPTARVTLGFQVTAQF
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]