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The map label for this gene is dxs [C]

Identifier: 83719464

GI number: 83719464

Start: 2224916

End: 2225824

Strand: Direct

Name: dxs [C]

Synonym: BTH_I1963

Alternate gene names: 83719464

Gene position: 2224916-2225824 (Clockwise)

Preceding gene: 83720625

Following gene: 83718778

Centisome position: 58.41

GC content: 72.06

Gene sequence:

>909_bases
ATGAGGCCCGCCGCCCATTGCGTGCAGGCGCTCGTCGAACGCGCCGCGCATGATCGCCGGATCTGGGTGCTGGACGGCGA
TCTCGCCGATTCCTACGGCGCGGACCGTTTCGCGGCGACCCATCCGGACCGCTTCCTGATGGCGGGGATCGCCGAACAGT
CGATGGTGTCGACGGCGGCGGGAATGGCCGCGTGCGGGCTGCGGCCGTGGGTGTTCTCGTTCGCGGCGTTCCTGTGCTAC
CGCGCCTACGATCAGATTCGCGTCGGTCTCGCGCAGGCCGGCATGCCCGTCACGCTCGTCGGCTCGCACAGCGGCGGCTG
CGGCGGCCCGAACGGCAAGAGTCATCTGGCGCTGAACGATATCGCGGTGATGGCGTCGCTGCCGAACGTCGACGTCTGGG
CGCCCGCGAGCGATCGCGATACGCGCTTCGTCGTCGATGCGGTGATGACGGCGGATCGGCCGGCCTACATCCGCTATCCG
CGCGAGCCTTGGGGCGAGCTGCCCGGCGAGCCCGCCGAGTGCCGATGGATCGGCGGGCGGCGCCGGTTCGCGCTCGTGAG
CTGCGGGCTGTTCTCGCACGTCGCAAACGACGCGGCCGGGATGTTGCGCGCACGCGGCATCGATGCGGGCGCGGTTCACG
TGGCGCGGCTCGCGCCGTTTCCCGCCGACGCTTTTGCCGCGCTCGTGGACGGCGTCGACGGAATCTGGGTCGTCGACGAT
CACACGCGCTTCGGCGGCCTGGCCGACCTGCTGCGCGCGAACGGTCACGCGGTTCGCGAACCCGCGTTCAGCTGGCCCGC
GAACTGGAGCGGCGACGTGGGGCCGGCGGCCGAACTGCTGCGGCGTCACGGCTTGTCCGCCGCCGACGTGGCCGGGCGGA
TCGCGGCCGAACTCGCGCGGGGGCGCTGA

Upstream 100 bases:

>100_bases
GCGGCATTCCCGCGTTCGAATGCGATCCCGGGCTGTCGCATTGCACGTCGCTCACCGACGATCAGTTCAGGCACGCGGTG
GCCGTCGCGGAGGGCGTGGC

Downstream 100 bases:

>100_bases
CGATGCCGGCCGATCTGCTCGTGACGGGGTCCGGCTCGCTTGCCGAGGCCGTGCTGTTCGATCTGATGTCGATGCCGGCG
CTCGCGGCGCCGATGACGAT

Product: transketolase, C-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRPAAHCVQALVERAAHDRRIWVLDGDLADSYGADRFAATHPDRFLMAGIAEQSMVSTAAGMAACGLRPWVFSFAAFLCY
RAYDQIRVGLAQAGMPVTLVGSHSGGCGGPNGKSHLALNDIAVMASLPNVDVWAPASDRDTRFVVDAVMTADRPAYIRYP
REPWGELPGEPAECRWIGGRRRFALVSCGLFSHVANDAAGMLRARGIDAGAVHVARLAPFPADAFAALVDGVDGIWVVDD
HTRFGGLADLLRANGHAVREPAFSWPANWSGDVGPAAELLRRHGLSAADVAGRIAAELARGR

Sequences:

>Translated_302_residues
MRPAAHCVQALVERAAHDRRIWVLDGDLADSYGADRFAATHPDRFLMAGIAEQSMVSTAAGMAACGLRPWVFSFAAFLCY
RAYDQIRVGLAQAGMPVTLVGSHSGGCGGPNGKSHLALNDIAVMASLPNVDVWAPASDRDTRFVVDAVMTADRPAYIRYP
REPWGELPGEPAECRWIGGRRRFALVSCGLFSHVANDAAGMLRARGIDAGAVHVARLAPFPADAFAALVDGVDGIWVVDD
HTRFGGLADLLRANGHAVREPAFSWPANWSGDVGPAAELLRRHGLSAADVAGRIAAELARGR
>Mature_302_residues
MRPAAHCVQALVERAAHDRRIWVLDGDLADSYGADRFAATHPDRFLMAGIAEQSMVSTAAGMAACGLRPWVFSFAAFLCY
RAYDQIRVGLAQAGMPVTLVGSHSGGCGGPNGKSHLALNDIAVMASLPNVDVWAPASDRDTRFVVDAVMTADRPAYIRYP
REPWGELPGEPAECRWIGGRRRFALVSCGLFSHVANDAAGMLRARGIDAGAVHVARLAPFPADAFAALVDGVDGIWVVDD
HTRFGGLADLLRANGHAVREPAFSWPANWSGDVGPAAELLRRHGLSAADVAGRIAAELARGR

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=293, Percent_Identity=30.0341296928328, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI4507521, Length=293, Percent_Identity=30.0341296928328, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI133778974, Length=304, Percent_Identity=28.2894736842105, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI225637459, Length=296, Percent_Identity=29.7297297297297, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI225637463, Length=296, Percent_Identity=29.7297297297297, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225637461, Length=296, Percent_Identity=29.7297297297297, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786622, Length=297, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17539652, Length=244, Percent_Identity=29.0983606557377, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45551847, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550715, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24645119, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666278, Length=155, Percent_Identity=36.1290322580645, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 32161; Mature: 32161

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAAHCVQALVERAAHDRRIWVLDGDLADSYGADRFAATHPDRFLMAGIAEQSMVSTAA
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GMAACGLRPWVFSFAAFLCYRAYDQIRVGLAQAGMPVTLVGSHSGGCGGPNGKSHLALND
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHH
IAVMASLPNVDVWAPASDRDTRFVVDAVMTADRPAYIRYPREPWGELPGEPAECRWIGGR
EEEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCCEEECCCCCHHCCCCCCCCEEEECCC
RRFALVSCGLFSHVANDAAGMLRARGIDAGAVHVARLAPFPADAFAALVDGVDGIWVVDD
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEC
HTRFGGLADLLRANGHAVREPAFSWPANWSGDVGPAAELLRRHGLSAADVAGRIAAELAR
CCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHC
GR
CC
>Mature Secondary Structure
MRPAAHCVQALVERAAHDRRIWVLDGDLADSYGADRFAATHPDRFLMAGIAEQSMVSTAA
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GMAACGLRPWVFSFAAFLCYRAYDQIRVGLAQAGMPVTLVGSHSGGCGGPNGKSHLALND
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHH
IAVMASLPNVDVWAPASDRDTRFVVDAVMTADRPAYIRYPREPWGELPGEPAECRWIGGR
EEEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCCEEECCCCCHHCCCCCCCCEEEECCC
RRFALVSCGLFSHVANDAAGMLRARGIDAGAVHVARLAPFPADAFAALVDGVDGIWVVDD
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEC
HTRFGGLADLLRANGHAVREPAFSWPANWSGDVGPAAELLRRHGLSAADVAGRIAAELAR
CCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]