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The map label for this gene is hisC-1 [H]

Identifier: 83719412

GI number: 83719412

Start: 524741

End: 525808

Strand: Reverse

Name: hisC-1 [H]

Synonym: BTH_I0471

Alternate gene names: 83719412

Gene position: 525808-524741 (Counterclockwise)

Preceding gene: 83719915

Following gene: 83718719

Centisome position: 13.8

GC content: 67.79

Gene sequence:

>1068_bases
GTGAGCCGTTACTGGAGCGACATCGTCCATCAACTCGAGCCGTACGTGCCGGGCGAGCAGCCGGCGCTCGCGCATCCCGT
CAAGCTGAACACGAACGAGAACCCGTATCCGCCGTCGCCGCGCGCGCTCGACGCGATTCGGCATGAGCTCGGCGCCACGG
GCGAGGCGCTGCGCCGCTATCCCGACCCCGTCGCGCGCAAGCTGCGCGAGACGGTCGCCGCCCATCACGGAATCGCGCCC
GAGCAGGTGTTCGCCGGCAACGGCTCCGACGAAGTGCTCGCGCATGCGTTCCAGGCGCTCCTGCAGCACGACAGGCCGCT
GCGCTTCCCGGACATCACGTACAGCTTCTACCCGACCTACGCACGGCTCTATCGCGTCGCATACGAGACGGTGCCGCTCG
CCGACGATTTCTCGATCGTCGTCGACGACTATCTCGACGACGCCGGCTGCGTGCTGTTCCCGAATCCGAACGCGCCGACG
GGCCGTGCGCTGCCGCTTGCCGACATCGAGCGGATCGTCGCCGCGAATCCGAGCTCGGTCGTCGTGATCGACGAGGCGTA
TGTCGACTTCGGCGCGGAGTCGGCCGTGTCGCTGATCTCGCGCTACCCGAACCTGCTCGTCGTGCATACCGCGTCGAAGG
CGCGCTCGCTCGCGGGCATGCGCGTCGGCTTCGCGTTCGGCGACGCCGCGCTGATCGATGCGCTCACACGCGTGAAGGAC
AGCTTCAACTCGTACCCGCTCGACCGTCTCGCGCAGGTGGCGACGCAGGCGTCGTACGAGGACGACGCGTGGTTCGAAGC
GACACGCAAGCAGGTGATCGCGAGCCGCGAGCGGCTTGTCGCCGCGCTCGCCGCGCTCGGCTTCGACGTCGTGCCGTCGG
CCGCGAATTTCGTGTTCGCGCGCCATCCTCGCCACGATGCGGCGACGCTTGCCGCACGACTGAAGCTACGGGAAATTTTC
GTGCGGCACTTCAAGCTGCCGCGAATCGACCAGCATTTGCGCATCACGGTCGGCACCGACGCAGAATGCGACGCGCTCGT
CGCCGCGCTGCGCGAATTGCTCGCGTAA

Upstream 100 bases:

>100_bases
ATGCAGCTGCATCGCAACGGCGCGTAAGCGCGCGCCTTCCCGCCCTCGCCGCCGCGCGCATCGGTTAAGCTCATCGTTTT
ACCGCATCGGGAGCCACGTG

Downstream 100 bases:

>100_bases
CGGGCAGCTCGCGCGGTCGACGCGCGAGCCAAAGCGATGTGAGGAAAATACGGCGGGCGGCGAATCGGGCGGCGAATCGG
CCGCCGTCACCGCGCGCGGG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRYWSDIVHQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRHELGATGEALRRYPDPVARKLRETVAAHHGIAP
EQVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTYARLYRVAYETVPLADDFSIVVDDYLDDAGCVLFPNPNAPT
GRALPLADIERIVAANPSSVVVIDEAYVDFGAESAVSLISRYPNLLVVHTASKARSLAGMRVGFAFGDAALIDALTRVKD
SFNSYPLDRLAQVATQASYEDDAWFEATRKQVIASRERLVAALAALGFDVVPSAANFVFARHPRHDAATLAARLKLREIF
VRHFKLPRIDQHLRITVGTDAECDALVAALRELLA

Sequences:

>Translated_355_residues
MSRYWSDIVHQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRHELGATGEALRRYPDPVARKLRETVAAHHGIAP
EQVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTYARLYRVAYETVPLADDFSIVVDDYLDDAGCVLFPNPNAPT
GRALPLADIERIVAANPSSVVVIDEAYVDFGAESAVSLISRYPNLLVVHTASKARSLAGMRVGFAFGDAALIDALTRVKD
SFNSYPLDRLAQVATQASYEDDAWFEATRKQVIASRERLVAALAALGFDVVPSAANFVFARHPRHDAATLAARLKLREIF
VRHFKLPRIDQHLRITVGTDAECDALVAALRELLA
>Mature_354_residues
SRYWSDIVHQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRHELGATGEALRRYPDPVARKLRETVAAHHGIAPE
QVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTYARLYRVAYETVPLADDFSIVVDDYLDDAGCVLFPNPNAPTG
RALPLADIERIVAANPSSVVVIDEAYVDFGAESAVSLISRYPNLLVVHTASKARSLAGMRVGFAFGDAALIDALTRVKDS
FNSYPLDRLAQVATQASYEDDAWFEATRKQVIASRERLVAALAALGFDVVPSAANFVFARHPRHDAATLAARLKLREIFV
RHFKLPRIDQHLRITVGTDAECDALVAALRELLA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=354, Percent_Identity=31.0734463276836, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1788722, Length=238, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=382, Percent_Identity=28.5340314136126, Blast_Score=106, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39145; Mature: 39014

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDIVHQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRHELGATGEALRRY
CCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHC
PDPVARKLRETVAAHHGIAPEQVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ARLYRVAYETVPLADDFSIVVDDYLDDAGCVLFPNPNAPTGRALPLADIERIVAANPSSV
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAESAVSLISRYPNLLVVHTASKARSLAGMRVGFAFGDAALIDALTRVKD
EEEEHHHHCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEHHHCHHHHHHHHHHHHH
SFNSYPLDRLAQVATQASYEDDAWFEATRKQVIASRERLVAALAALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHEEEE
RHPRHDAATLAARLKLREIFVRHFKLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SRYWSDIVHQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRHELGATGEALRRY
CHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHC
PDPVARKLRETVAAHHGIAPEQVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ARLYRVAYETVPLADDFSIVVDDYLDDAGCVLFPNPNAPTGRALPLADIERIVAANPSSV
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAESAVSLISRYPNLLVVHTASKARSLAGMRVGFAFGDAALIDALTRVKD
EEEEHHHHCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEHHHCHHHHHHHHHHHHH
SFNSYPLDRLAQVATQASYEDDAWFEATRKQVIASRERLVAALAALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHEEEE
RHPRHDAATLAARLKLREIFVRHFKLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA