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The map label for this gene is hexR [H]

Identifier: 83719395

GI number: 83719395

Start: 620125

End: 621018

Strand: Direct

Name: hexR [H]

Synonym: BTH_I0545

Alternate gene names: 83719395

Gene position: 620125-621018 (Clockwise)

Preceding gene: 83721601

Following gene: 83719564

Centisome position: 16.28

GC content: 72.26

Gene sequence:

>894_bases
ATGACGCCGTCCGCCGAGCAGCCCGCCTTCGACATCGTCGCCCGGATCGCCGAGTGCGCGCCCGAGTTGCGCGACGCGGA
GCGCAAGGTCGCGGCGCTGATCCTCGGCGATCTGACTCAGGCCGCGCACGCGAGCATCGGCGCGCTCGCCGCGCACGCGG
ACGTGAGCGTGGCCACCGTCACGCGCTTCGCGAAGGCGGTGGGCTGCCGCGACGTGCGCGAGCTCAAGCTGCGGCTCGCG
CAGGCGGCCGCGGTCGGCCAGCGCTTTCTGACCCCGGCCGCGGCCGATGCGCAGTGCGACGAGACGCCCGTTTCGCGCGT
ATACGGAGACGTGCAGGTCGCGCTCGAGCACAACCATCGGCTGCTGCGCCAGACGTCGTTCGACGCGCCCGCCGCCGCGC
TCGCCGCCGCGAACATGATCTACGTGTACGGGCAGGGCGGCGGCTCGACCGCGCTCGCCGACGAGCTGCGCTTTCGCCTC
GTGCGCTTCGGCCGGCCGGTCGCGACCTACCAGGACGCATTGCTGCAGCGGATGGTCGCCACCACCGCGGCGCCCGGCTG
CGTGGTCGTCGCGCTGTCGGTGTCGGGGCGCATCCCGGAGCAGCTCGAAAGCTGCGCGCTCGCGAAGCGCTACGGCGCGA
CGCTCGTCGCGCTCACCGCGCCCGCGTCGCCGCTCGCGCAGCTCGCCGATCATCTGATTCCCGTCGTCGCGTTCGAAACC
GATTTCATCTTCAAGCCGTCGGCATCGCGCTACGCGATGCTGATGGCGCTCGACGTGCTCGTCACCGAAGTCGCGCTGCG
CCTGGGCGACGACTGCCGCGAGCTGCTGCGCCGGATGAAGCACGCGCTCGACATGCACCGCGGCGGCGGCGACCGCCAAC
CGTTAGGAGACTGA

Upstream 100 bases:

>100_bases
GTTGACTTCGCGATAGTACAGAAAGTAGCATCGCTGCGGTAATGTTATTTATTAACACGCCGGTTCGCACCGGCCGTCCC
CATCGACCGAGCCCCGCCTC

Downstream 100 bases:

>100_bases
CATGCACTCGCATCCCGAAGCGGCCGATACGCTGATCGTCGGCGCGCAGTTGTACGACGGCACGGGCGCGCCGAGCGTCG
AGCGCGACGTGGCGATTCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTPSAEQPAFDIVARIAECAPELRDAERKVAALILGDLTQAAHASIGALAAHADVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLTPAAADAQCDETPVSRVYGDVQVALEHNHRLLRQTSFDAPAAALAAANMIYVYGQGGGSTALADELRFRL
VRFGRPVATYQDALLQRMVATTAAPGCVVVALSVSGRIPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
DFIFKPSASRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGDRQPLGD

Sequences:

>Translated_297_residues
MTPSAEQPAFDIVARIAECAPELRDAERKVAALILGDLTQAAHASIGALAAHADVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLTPAAADAQCDETPVSRVYGDVQVALEHNHRLLRQTSFDAPAAALAAANMIYVYGQGGGSTALADELRFRL
VRFGRPVATYQDALLQRMVATTAAPGCVVVALSVSGRIPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
DFIFKPSASRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGDRQPLGD
>Mature_296_residues
TPSAEQPAFDIVARIAECAPELRDAERKVAALILGDLTQAAHASIGALAAHADVSVATVTRFAKAVGCRDVRELKLRLAQ
AAAVGQRFLTPAAADAQCDETPVSRVYGDVQVALEHNHRLLRQTSFDAPAAALAAANMIYVYGQGGGSTALADELRFRLV
RFGRPVATYQDALLQRMVATTAAPGCVVVALSVSGRIPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFETD
FIFKPSASRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGDRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=287, Percent_Identity=32.7526132404181, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788767, Length=284, Percent_Identity=23.5915492957746, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082369, Length=254, Percent_Identity=24.8031496062992, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31624; Mature: 31493

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSAEQPAFDIVARIAECAPELRDAERKVAALILGDLTQAAHASIGALAAHADVSVATV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLTPAAADAQCDETPVSRVYGDVQVALEHNHR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEHHHHHH
LLRQTSFDAPAAALAAANMIYVYGQGGGSTALADELRFRLVRFGRPVATYQDALLQRMVA
HHHHCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TTAAPGCVVVALSVSGRIPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECC
DFIFKPSASRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGDRQPLGD
CEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TPSAEQPAFDIVARIAECAPELRDAERKVAALILGDLTQAAHASIGALAAHADVSVATV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLTPAAADAQCDETPVSRVYGDVQVALEHNHR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEHHHHHH
LLRQTSFDAPAAALAAANMIYVYGQGGGSTALADELRFRLVRFGRPVATYQDALLQRMVA
HHHHCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TTAAPGCVVVALSVSGRIPEQLESCALAKRYGATLVALTAPASPLAQLADHLIPVVAFET
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECC
DFIFKPSASRYAMLMALDVLVTEVALRLGDDCRELLRRMKHALDMHRGGGDRQPLGD
CEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]