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The map label for this gene is glpR [H]

Identifier: 83719343

GI number: 83719343

Start: 686644

End: 687480

Strand: Reverse

Name: glpR [H]

Synonym: BTH_I0603

Alternate gene names: 83719343

Gene position: 687480-686644 (Counterclockwise)

Preceding gene: 83719171

Following gene: 83718761

Centisome position: 18.05

GC content: 65.59

Gene sequence:

>837_bases
ATGCGGATTTGCCGCCCCCGTTTCCCGTCCCACCGAGCCGAATCGACACCCGCGAACATGACACGAGACCCCCGCCTCAC
CCTCAATGCGCGTCAACAGGAATTGCTCGAATGGGTGCAGCGAGACGGCTTCGTCACTGTCGACGATCTCGCCGCCCATT
TCAACGTAACGCCGCAGACGATCCGCCGCGACGTCAACTGGCTCGCCGACCTGAACCTGCTGCGCCGCTACCACGGCGGC
GCGAGCCTGCCGACGAGCTCGGAGAACGTGTCGTACACCGCGCGCCAGCGGATGTTCCACGACGAAAAGCGCCGGATCGC
GGCGCTCGCCGCGTCGCACATCCCCGATCAGGCGTCCCTGTTCATCAATCTCGGCACGACGACCGAAGAAGTCGCGCGCG
CGCTGAACCGGCATCGCGGCCTGCGCGTGATCACGAACAACCTGAACGTCGCGAGCATGATGAGCGGCTATCCGGAATGC
GAGGTGCTGATCACGGGCGGCATCGTGCGGCCTTGGGACAAGGGCATCGTCGGCGAGCTCGCGATCGACTTCATCCGCCA
GTTCAGGGTCGACTACGCGATCATCGGCACGTCGTCGATCGAGAGCGACGGCACGCTGCGCGATTTCGACACGCGCGAGG
TGCGCGTCGCCGAGGCGATCATCCAGCACGCGCGAACCGTCTATCTCGTCACCGACCATTCGAAGTTCGGCCGCCCGGCG
CTCGTGCGGCAGGGGCATCTGAACCAGATCCACGCGCTCTTCACCGACAAGCCGCTGCCCGACGAGATGGCCGAAACGAT
CGCGCAGGCGGGCACACAGGTCTACGTCGCCGACTGA

Upstream 100 bases:

>100_bases
CGATGCATGAACGACATGAATCGAGTCTAGCCCGAGATCGGCGCGCGTGCGCGGCGACGCGCGCCGCGTGCCGGGCGACT
CCGCGCGAACAGCCCTTACA

Downstream 100 bases:

>100_bases
GCGGCCCGTGCGTGCTCGGCGTCGCGCGATGCTGCGTCGCACCCAGAACTTCAAGTGAAATCAAGGAATTGCCGCACCGG
CGCAACCGCCTGACGATTTC

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MRICRPRFPSHRAESTPANMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFNVTPQTIRRDVNWLADLNLLRRYHGG
ASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVITNNLNVASMMSGYPEC
EVLITGGIVRPWDKGIVGELAIDFIRQFRVDYAIIGTSSIESDGTLRDFDTREVRVAEAIIQHARTVYLVTDHSKFGRPA
LVRQGHLNQIHALFTDKPLPDEMAETIAQAGTQVYVAD

Sequences:

>Translated_278_residues
MRICRPRFPSHRAESTPANMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFNVTPQTIRRDVNWLADLNLLRRYHGG
ASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVITNNLNVASMMSGYPEC
EVLITGGIVRPWDKGIVGELAIDFIRQFRVDYAIIGTSSIESDGTLRDFDTREVRVAEAIIQHARTVYLVTDHSKFGRPA
LVRQGHLNQIHALFTDKPLPDEMAETIAQAGTQVYVAD
>Mature_278_residues
MRICRPRFPSHRAESTPANMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFNVTPQTIRRDVNWLADLNLLRRYHGG
ASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVITNNLNVASMMSGYPEC
EVLITGGIVRPWDKGIVGELAIDFIRQFRVDYAIIGTSSIESDGTLRDFDTREVRVAEAIIQHARTVYLVTDHSKFGRPA
LVRQGHLNQIHALFTDKPLPDEMAETIAQAGTQVYVAD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=230, Percent_Identity=48.2608695652174, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI87082344, Length=235, Percent_Identity=41.2765957446808, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=30.4347826086957, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=27.710843373494, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=26.9076305220884, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=28.6290322580645, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI226510968, Length=248, Percent_Identity=28.6290322580645, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=30.0429184549356, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787063, Length=246, Percent_Identity=28.8617886178862, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790635, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 31368; Mature: 31368

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRICRPRFPSHRAESTPANMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFNVTPQT
CCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHH
IRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FINLGTTTEEVARALNRHRGLRVITNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGEL
EEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
AIDFIRQFRVDYAIIGTSSIESDGTLRDFDTREVRVAEAIIQHARTVYLVTDHSKFGRPA
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCH
LVRQGHLNQIHALFTDKPLPDEMAETIAQAGTQVYVAD
HHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MRICRPRFPSHRAESTPANMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFNVTPQT
CCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHH
IRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FINLGTTTEEVARALNRHRGLRVITNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGEL
EEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
AIDFIRQFRVDYAIIGTSSIESDGTLRDFDTREVRVAEAIIQHARTVYLVTDHSKFGRPA
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCH
LVRQGHLNQIHALFTDKPLPDEMAETIAQAGTQVYVAD
HHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]