The gene/protein map for NC_004578 is currently unavailable.
Definition Burkholderia thailandensis E264 chromosome chromosome I, complete sequence.
Accession NC_007651
Length 3,809,201

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The map label for this gene is phbB [H]

Identifier: 83719268

GI number: 83719268

Start: 2539720

End: 2540502

Strand: Direct

Name: phbB [H]

Synonym: BTH_I2257

Alternate gene names: 83719268

Gene position: 2539720-2540502 (Clockwise)

Preceding gene: 83719964

Following gene: 83718582

Centisome position: 66.67

GC content: 62.71

Gene sequence:

>783_bases
TTGCCGCTCGGCGCTTCTCAAAACGATAATGGAGTGTGGGTTATGTCTCAGCGAATTGCTTACGTAACGGGCGGAATGGG
CGGCATCGGCACCAGCATCTGCCAGCGCCTGCACAAGGACGGCTTCAGGGTGGTCGCGGGCTGCGGCCCGAATTCGCCGC
GCCGCGTGAAATGGCTTGAGGACCAGAAGGCGCTCGGCTTCGATTTCTACGCGTCCGAAGGCAACGTCGGCGACTGGGAT
TCGACGAAGCAGGCATTCGACAAGGTGAAGGCCGAGATCGGCGAGATCGACGTGCTCGTCAACAACGCGGGCATTACGCG
CGACGTCGTGTTCCGCAAGATGACGCGCGAGGACTGGACGGCCGTGATCGACACGAACCTGACGAGCCTCTTCAACGTCA
CGAAGCAAGTGATCGACGGCATGGTCGAGCGCGGCTGGGGACGCATCATCAACATCTCGTCGGTGAACGGGCAGAAAGGG
CAGTTCGGCCAGACCAACTACTCGACCGCGAAGGCGGGCATTCACGGCTTCACGATGTCGCTCGCGCAGGAAGTGGCGAC
GAAGGGCGTGACGGTCAACACGGTGTCGCCGGGCTACATCGGCACGGACATGGTGAAGGCGATCCGTCCGGACGTGCTCG
AGAAGATCGTCGCGACGATTCCGGTGCGCCGTCTCGGCTCGCCCGACGAGATCGGCTCGATCGTCGCGTGGCTCGCGTCG
GAAGAGTCCGGCTTTGCGACGGGCGCCGATTTTTCGCTGAACGGCGGCTTGCATATGGGCTGA

Upstream 100 bases:

>100_bases
CGCTCGAGCGCCCGTAACGCGAGTCAGGAGGCACCCGAGCGGGCCGTGCCGACAGGCGCGGCCCGGCGTCGGGCGAAAAG
GCAGGCGGGCGACGGAGAGG

Downstream 100 bases:

>100_bases
GCCATGCGGCCGGACGGCGCATGCCGTCCGGCCGTGTGGGTCGGATGTTCCGGGAACGCCCGGTTCGCGCGCGGCCGCGC
CCGCGTGCGGCGCCGGGCGC

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MPLGASQNDNGVWVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWD
STKQAFDKVKAEIGEIDVLVNNAGITRDVVFRKMTREDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKG
QFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLAS
EESGFATGADFSLNGGLHMG

Sequences:

>Translated_260_residues
MPLGASQNDNGVWVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWD
STKQAFDKVKAEIGEIDVLVNNAGITRDVVFRKMTREDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKG
QFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLAS
EESGFATGADFSLNGGLHMG
>Mature_259_residues
PLGASQNDNGVWVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDS
TKQAFDKVKAEIGEIDVLVNNAGITRDVVFRKMTREDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQ
FGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASE
ESGFATGADFSLNGGLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=35.9683794466403, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=31.8897637795276, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4504505, Length=236, Percent_Identity=32.2033898305085, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=28.1124497991968, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.3149606299213, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.4193548387097, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=28.8770053475936, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=30.4123711340206, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=31.1004784688995, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=28.0788177339901, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=24.6861924686192, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40548397, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI214010158, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI214010156, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI22758144, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.6116504854369, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI22507405, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=26.5, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI44680136, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI50726952, Length=193, Percent_Identity=30.0518134715026, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=43.801652892562, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=36.2549800796813, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=30.952380952381, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.1652892561983, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=28.740157480315, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=29.4354838709677, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.1632653061224, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=34.0540540540541, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=29.045643153527, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=24.9027237354086, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=41.3934426229508, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=37.246963562753, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=29.1497975708502, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=32.6612903225806, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.496062992126, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=29.2, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.1338582677165, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=27.9166666666667, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.6, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=202, Percent_Identity=30.1980198019802, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=31.1224489795918, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.5454545454545, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.968253968254, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.8884462151394, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=26.8939393939394, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.0377358490566, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.2388059701493, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=28.1746031746032, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=28.6274509803922, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=28.1481481481481, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.2030651340996, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=141, Percent_Identity=30.4964539007092, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=26.3940520446097, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=24.5283018867925, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=26.7657992565056, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=26.2589928057554, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=211, Percent_Identity=23.696682464455, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=211, Percent_Identity=24.1706161137441, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=184, Percent_Identity=25.5434782608696, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=25.4612546125461, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=31.3492063492063, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=34.1269841269841, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.1587301587302, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=27.6, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21357041, Length=174, Percent_Identity=37.3563218390805, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.3501945525292, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=31.3559322033898, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=34.3195266272189, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=25.9887005649718, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706930, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706928, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706926, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706924, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706922, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 27949; Mature: 27818

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MPLGASQNDNGVWVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLE
CCCCCCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DQKALGFDFYASEGNVGDWDSTKQAFDKVKAEIGEIDVLVNNAGITRDVVFRKMTREDWT
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
AVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMS
EEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLAS
HHHHHHHCCCEEECCCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHC
EESGFATGADFSLNGGLHMG
CCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
PLGASQNDNGVWVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLE
CCCCCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DQKALGFDFYASEGNVGDWDSTKQAFDKVKAEIGEIDVLVNNAGITRDVVFRKMTREDWT
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
AVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMS
EEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLAS
HHHHHHHCCCEEECCCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHC
EESGFATGADFSLNGGLHMG
CCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]