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The map label for this gene is tpm [H]

Identifier: 83719252

GI number: 83719252

Start: 635323

End: 636060

Strand: Direct

Name: tpm [H]

Synonym: BTH_I0557

Alternate gene names: 83719252

Gene position: 635323-636060 (Clockwise)

Preceding gene: 83718588

Following gene: 83718516

Centisome position: 16.68

GC content: 73.71

Gene sequence:

>738_bases
ATGACGAGCGAAGCGAACAAAGGTGACGCGGCCGTGCAGGCGGCGGGCGATGCGCAACCGGCGAGTCCGGCAAGTCCGCC
GTCCGCGGACGTGCAGCCCGCACGGGCCGCGTTGGCCCCGTCTTCCGTGCCGCCCGCCCCGTCGGCCGCGAACTTCGCGT
CGCGCGATCCGGGCGACGCGTCGTTCTGGGACGAGCGCTTCGAGCGGGGCGTGACGCCGTGGGACAGCGCGCGCGTGCCG
GACGCGTTCGCCGCATTCGCCGCGCGGCATCCGCGATGCCCCGTGCTGATTCCCGGCTGCGGCAGCGCGTACGAGGCGCG
TTGGCTCGCGCGCGCCGGCTGGCCCGTGCGCGCGATCGACTTCTCCGCCCAGGCGGTCGCTGCCGCGCGCCGCGAATCGG
GTGCAGATGCCGCGCTCGTCGAGCAGGCCGATTTCTTCGCGTACGTGCCGCCGTTCGTCCCGCAGTGGATCTACGAGCGC
GCGTTCCTGTGCGCGATTCCGACGAGCCGCCGCGCCGACTACGCGCGGCGCGTGGCCGAGCTGCTGCCGGCGGGCGGCTT
CCTCGCCGGCTTCTTCTTCATTGGCGCGACGCCAAAGGGGCCGCCGTTCGGGATCGAGCGCGCGGAGCTCGACGCGCTGC
TTTCGCCGAACTTCGAGCTCGTCGAGGACGAGCCCGTTGCCGATTCGCTGCCGGTGTTCGCCGGACGCGAGCGCTGGCTC
GCGTGGCGCCGCTCGTAG

Upstream 100 bases:

>100_bases
GCGAGGCACGCGCGGATCGGCGGGCGGATGCGCTCGGCGGGCGGCGCAGCCTGCGGACGAAGGGTGAATGAAGGATAAGG
TTACGAGGCGGAGCGACGGC

Downstream 100 bases:

>100_bases
CGGTGCCGCGCGCGGCACCGGAGCGCGCCCGCCTTTCGGCTATAATTCAAGGCTTTGCAAGCCTTTTATACGTTTCTGCG
GGAAAATACCATGCCGATCT

Product: thiopurine S-methyltransferase family protein

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTSEANKGDAAVQAAGDAQPASPASPPSADVQPARAALAPSSVPPAPSAANFASRDPGDASFWDERFERGVTPWDSARVP
DAFAAFAARHPRCPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRESGADAALVEQADFFAYVPPFVPQWIYER
AFLCAIPTSRRADYARRVAELLPAGGFLAGFFFIGATPKGPPFGIERAELDALLSPNFELVEDEPVADSLPVFAGRERWL
AWRRS

Sequences:

>Translated_245_residues
MTSEANKGDAAVQAAGDAQPASPASPPSADVQPARAALAPSSVPPAPSAANFASRDPGDASFWDERFERGVTPWDSARVP
DAFAAFAARHPRCPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRESGADAALVEQADFFAYVPPFVPQWIYER
AFLCAIPTSRRADYARRVAELLPAGGFLAGFFFIGATPKGPPFGIERAELDALLSPNFELVEDEPVADSLPVFAGRERWL
AWRRS
>Mature_244_residues
TSEANKGDAAVQAAGDAQPASPASPPSADVQPARAALAPSSVPPAPSAANFASRDPGDASFWDERFERGVTPWDSARVPD
AFAAFAARHPRCPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRESGADAALVEQADFFAYVPPFVPQWIYERA
FLCAIPTSRRADYARRVAELLPAGGFLAGFFFIGATPKGPPFGIERAELDALLSPNFELVEDEPVADSLPVFAGRERWLA
WRRS

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 26200; Mature: 26069

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEANKGDAAVQAAGDAQPASPASPPSADVQPARAALAPSSVPPAPSAANFASRDPGDA
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SFWDERFERGVTPWDSARVPDAFAAFAARHPRCPVLIPGCGSAYEARWLARAGWPVRAID
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEC
FSAQAVAAARRESGADAALVEQADFFAYVPPFVPQWIYERAFLCAIPTSRRADYARRVAE
CCHHHHHHHHHHCCCCHHHHHHCCHHEECCCHHHHHHHHCEEEEECCCCHHHHHHHHHHH
LLPAGGFLAGFFFIGATPKGPPFGIERAELDALLSPNFELVEDEPVADSLPVFAGRERWL
HCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHH
AWRRS
HCCCC
>Mature Secondary Structure 
TSEANKGDAAVQAAGDAQPASPASPPSADVQPARAALAPSSVPPAPSAANFASRDPGDA
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SFWDERFERGVTPWDSARVPDAFAAFAARHPRCPVLIPGCGSAYEARWLARAGWPVRAID
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEC
FSAQAVAAARRESGADAALVEQADFFAYVPPFVPQWIYERAFLCAIPTSRRADYARRVAE
CCHHHHHHHHHHCCCCHHHHHHCCHHEECCCHHHHHHHHCEEEEECCCCHHHHHHHHHHH
LLPAGGFLAGFFFIGATPKGPPFGIERAELDALLSPNFELVEDEPVADSLPVFAGRERWL
HCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHH
AWRRS
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA