Click here to switch to the map view.

The map label for this gene is cobJ [H]

Identifier: 83719162

GI number: 83719162

Start: 2729761

End: 2731572

Strand: Direct

Name: cobJ [H]

Synonym: BTH_I2401

Alternate gene names: 83719162

Gene position: 2729761-2731572 (Clockwise)

Preceding gene: 83720325

Following gene: 83718845

Centisome position: 71.66

GC content: 75.11

Gene sequence:

>1812_bases
ATGGCAAGGATGACCGCCGCGCCCGCGATCGTGATACTCGGGCCCGGCGCGCTCGATACCGCGCGCCGAATCCAGGCCCG
CTACGACGGCGCTCGGGTGCATGCGCTCGCGGGGCGCGCCGAAGCCGACGTGACGTTCCGCGAGCTGGGCCCGCATCTGC
GCGAGCTGTACGCGCGCGGCGCGCCGATCGTCGCGCTGTTTGCGGCCGGCATCGCGATCCGCTGCGTCGCGCCGTGCCTC
GCCGACAAGGGCGCGGAGCCGCCCGTGCTCGCCGTTGCCGAGGACGGCAGCGCGGTCGTGCCGCTGTTGGGCGGCCTCGC
GGGCGCGAACGCGCTCGCGCGCGAGATCGCCGACACGCTCGGCGTCGCCGCCGCGATCACGACGAGCGGCGAGCTGCGCT
TCGGCGCGTGCATGCTCAATCCGCCCGAAGGCTACGCGCTCGCCGATCTCGACGCGGGCAAGCGCTTCGTGTCCGATCTG
CTCGCGGGCGAAAGCACGCGCATCGAAGGCGACGCGCGGTGGCTCGACGACGTCGCGCTGCCGCGCGACGCGCACGCGGC
GCATGCGATCCGCGTCACGCCGCACGCGTCGCGCGGCGGCGCACGCGAATTGCTGATTCATCCGCGCAGCGTCGTCGCCG
CGCTCGGCGACGACGCGGACAACGTTTCGGAGCACGACGCAATCGTACGCGCCAGCGCGGCCGCGAACGCGCTCGCCGCA
TCGCCCGACCTGCCGCCGCTCGCCGCGCGCATCGTCGCGGCGCTCGCCGCGCGCGATCTCGCGCCGCTCGCGCTCGCGGC
CATCGTCGCGCCGGCGCGGCGCATCGCCGATCGCGCGCTGACCGACGCGGCGCGCGCGCTGCGCGTGCCGTTGCGCTTCG
TCGAAACGAACGCGTGTGACGCCGCGGGCGTGCTCAATGCCGCGCTGCCCGCCGCGCTCGCGCCGCGCGCCGACGCATCG
CGCGCCGGCTCGTGCTCCGGCTCGACGCAAACGCCGCACGACATCGCGATCGCCGTCGCCGGCGCGCCCGTCGACGCCGA
TACGCTCGGCGTCGCGCGCGGCCGCCTGACGGTGCTCGGCCTCGGCCCCGGCCGAGCGGACCTGATGACGCCCGCCGCAC
GCGCGGCGCTCGCCGATGCGACCGACATCGTCGGCTACGCGACCTACGTGAACATGGCGGGCCCGTTGCGCGCCGACCAG
CAACTGCACCTCTCCGAGAACCGCGAGGAACTGCAGCGCGCGCGCCACGCGTTCGAGCTCGCCGCGCAGGGCCGGCGGGT
CGCGGTCGTGTCGTCGGGCGACCCCGGCGTGTTCGCGATGGCGGCGGCCGTGCTCGAAGCGCTCGACGGCTCCAACGACA
CGCGCTGGGCGGCCGTCGAGCTCGACATCGTGCCCGGCGTGTCGGCCGCGCTCGCGACGGCGGCCGAGGCGGGCGCGCCG
CTCGGCCACGACTTCTGCCTGATCTCGCTGTCGGACAACCTGAAGCCGTGGGCGATCATCGAAAAGCGCATCGACCACGC
GGCGGCCGCCGATTTCGCGCTCGCGTTCTACAACCCGGTGTCGCGCGCACGGCCCGTGCAATTCGACCGCGCGCTCGACG
TCGTGCGCCGGCATCGCGCGCCGGAGACGGTCGTCGTGCTCGGCCGCGACATCGGCCGCCCGGGCGCGACGCTCGCGACG
ACGACGCTCGCCGCGCTGTCCGCGCAGCAAGTCGACATGCGCACGATGGTGATCGTCGGCTCGTCGACGACGCGCCGCGT
CGTGCGCGACGGCGCGCGCGAATGGGTGTACACGCCGCGCTGGTATCGCTGA

Upstream 100 bases:

>100_bases
TCGAGCGCGCGACGATGGCCGCGCAGCGGATCGTGCCGCTCGCGGAAGTCGATCCGATGGCGTCGCCGTATTTTTCGCTG
CTCGTCGTGCCGGGGGAAAA

Downstream 100 bases:

>100_bases
CGGCGAAGCGACGCTCGGCTCGCGTCGCTTCGTGAATCGGCCACGAACGATCGGGCGCCGAGCGCGCCCGAGCCGCGATC
CGCGCGAGCCTGACGCTCCC

Product: cbiG protein/precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MARMTAAPAIVILGPGALDTARRIQARYDGARVHALAGRAEADVTFRELGPHLRELYARGAPIVALFAAGIAIRCVAPCL
ADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADTLGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDL
LAGESTRIEGDARWLDDVALPRDAHAAHAIRVTPHASRGGARELLIHPRSVVAALGDDADNVSEHDAIVRASAAANALAA
SPDLPPLAARIVAALAARDLAPLALAAIVAPARRIADRALTDAARALRVPLRFVETNACDAAGVLNAALPAALAPRADAS
RAGSCSGSTQTPHDIAIAVAGAPVDADTLGVARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQ
QLHLSENREELQRARHAFELAAQGRRVAVVSSGDPGVFAMAAAVLEALDGSNDTRWAAVELDIVPGVSAALATAAEAGAP
LGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDVVRRHRAPETVVVLGRDIGRPGATLAT
TTLAALSAQQVDMRTMVIVGSSTTRRVVRDGAREWVYTPRWYR

Sequences:

>Translated_603_residues
MARMTAAPAIVILGPGALDTARRIQARYDGARVHALAGRAEADVTFRELGPHLRELYARGAPIVALFAAGIAIRCVAPCL
ADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADTLGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDL
LAGESTRIEGDARWLDDVALPRDAHAAHAIRVTPHASRGGARELLIHPRSVVAALGDDADNVSEHDAIVRASAAANALAA
SPDLPPLAARIVAALAARDLAPLALAAIVAPARRIADRALTDAARALRVPLRFVETNACDAAGVLNAALPAALAPRADAS
RAGSCSGSTQTPHDIAIAVAGAPVDADTLGVARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQ
QLHLSENREELQRARHAFELAAQGRRVAVVSSGDPGVFAMAAAVLEALDGSNDTRWAAVELDIVPGVSAALATAAEAGAP
LGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDVVRRHRAPETVVVLGRDIGRPGATLAT
TTLAALSAQQVDMRTMVIVGSSTTRRVVRDGAREWVYTPRWYR
>Mature_602_residues
ARMTAAPAIVILGPGALDTARRIQARYDGARVHALAGRAEADVTFRELGPHLRELYARGAPIVALFAAGIAIRCVAPCLA
DKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADTLGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLL
AGESTRIEGDARWLDDVALPRDAHAAHAIRVTPHASRGGARELLIHPRSVVAALGDDADNVSEHDAIVRASAAANALAAS
PDLPPLAARIVAALAARDLAPLALAAIVAPARRIADRALTDAARALRVPLRFVETNACDAAGVLNAALPAALAPRADASR
AGSCSGSTQTPHDIAIAVAGAPVDADTLGVARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQ
LHLSENREELQRARHAFELAAQGRRVAVVSSGDPGVFAMAAAVLEALDGSNDTRWAAVELDIVPGVSAALATAAEAGAPL
GHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDVVRRHRAPETVVVLGRDIGRPGATLATT
TLAALSAQQVDMRTMVIVGSSTTRRVVRDGAREWVYTPRWYR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 62522; Mature: 62391

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMTAAPAIVILGPGALDTARRIQARYDGARVHALAGRAEADVTFRELGPHLRELYARG
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHCHHHHHHHHCC
APIVALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADTL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
GVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRIEGDARWLDDVAL
HHHEEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCC
PRDAHAAHAIRVTPHASRGGARELLIHPRSVVAALGDDADNVSEHDAIVRASAAANALAA
CCCCCCCEEEEECCCCCCCCCCEEEECHHHHHHHHCCCCCCCCHHHHHEEHHHHHHHHCC
SPDLPPLAARIVAALAARDLAPLALAAIVAPARRIADRALTDAARALRVPLRFVETNACD
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCC
AAGVLNAALPAALAPRADASRAGSCSGSTQTPHDIAIAVAGAPVDADTLGVARGRLTVLG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCCEEEEE
LGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHLSENREELQRARHAFEL
ECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AAQGRRVAVVSSGDPGVFAMAAAVLEALDGSNDTRWAAVELDIVPGVSAALATAAEAGAP
HHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCC
LGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDVVRRHRA
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCC
PETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVVRDGAREWVYTPR
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCHHCCCCCC
WYR
CCC
>Mature Secondary Structure 
ARMTAAPAIVILGPGALDTARRIQARYDGARVHALAGRAEADVTFRELGPHLRELYARG
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHCHHHHHHHHCC
APIVALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADTL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
GVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRIEGDARWLDDVAL
HHHEEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCC
PRDAHAAHAIRVTPHASRGGARELLIHPRSVVAALGDDADNVSEHDAIVRASAAANALAA
CCCCCCCEEEEECCCCCCCCCCEEEECHHHHHHHHCCCCCCCCHHHHHEEHHHHHHHHCC
SPDLPPLAARIVAALAARDLAPLALAAIVAPARRIADRALTDAARALRVPLRFVETNACD
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCC
AAGVLNAALPAALAPRADASRAGSCSGSTQTPHDIAIAVAGAPVDADTLGVARGRLTVLG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCCEEEEE
LGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHLSENREELQRARHAFEL
ECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AAQGRRVAVVSSGDPGVFAMAAAVLEALDGSNDTRWAAVELDIVPGVSAALATAAEAGAP
HHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCC
LGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDVVRRHRA
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCC
PETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVVRDGAREWVYTPR
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCHHCCCCCC
WYR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]