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The map label for this gene is dacC [H]

Identifier: 83718804

GI number: 83718804

Start: 422220

End: 423530

Strand: Direct

Name: dacC [H]

Synonym: BTH_I0380

Alternate gene names: 83718804

Gene position: 422220-423530 (Clockwise)

Preceding gene: 83721347

Following gene: 83719495

Centisome position: 11.08

GC content: 67.66

Gene sequence:

>1311_bases
ATGCGTCTGTCTTCCCTCGGCCTCACGTCACTCGCTTCCTCCACCGCCATTGCCGTCGCCGCGCGCAACGTCGCGCTCGG
CATCGTGCTGCCCGCCGCGCTCGTGTCGACGATCGCCGTCGCGCAGGCGAAGCCCGCCGCCAAGGCGAAGCACGCGGCCG
CGCCGGCCGCCGCCGCGCCGACGGGCGCGCCCGCCACTTATGCGCCGGGCGCCGTGCCGCCGCCGGGCGTGAACGCGCGC
TCGTGGGTGCTCGTCGACGCGTCGAGCAACCAGGTGCTCGCCTCCGGCAACGCGGACGAGCGCGTCGAGCCGGCGTCGCT
CACGAAGCTGATGACGGCCTACCTCGTGTTCGAGGCGCTCGACGCGAAGAAGATCACGATGGAGCAGATCGTCACGCCGA
GCGAGGCAGTGCGCCGCGTCGGCCGCGACGAGTCGCGGATGTTCATCGAGGCGAACAAGCCCGTCAGCGTGCACGATCTC
GTCTACGGGATGATCATCCAGTCGGGCAACGACGCGGCGATCGCGCTCGCCGAGCTCGTCGGCGGCAGCGAGGCGCAGTT
CGTCAACATGATGAACGCTGAAGCGCAGCGCCTCGGGATGAAGAACACGCACTTCGCCGACGTGAACGGCATGCCCGACC
CGAACCACTACACGACGGCGGGCGATCTCGCGACGCTGTCGACGCACCTGATCCGCGACTATCCGGATTACTACAACATC
TTCTCGGTCAAGGAATTCACGTACAACAACATCAAGCAGCCGAACCGCAACCGGCTGCTGTGGCTCGATCCGACCGTCGA
CGGCCTGAAGACCGGCCACACGCAGGCGGCCGGGTACTGCCTGATCGCGTCGGCGAAGCGTTCGCTGCCGGGCGCGGCCG
ATGCGACGCGCCGCCTCGTCACGGTGATGATGGGCGAGACGAAGGAGAGCGACCGCGTGCAGGACAGCATGAAGATGCTG
AACTACGGCTACACCGCGTTCGATTCGGTGCGCCTGTACAAGGCCGGCCAGCCGATCGACACGCCGCGCGTCTATAAGGG
CAAGAGCAACAACGTGCAGGTCGGCGTGAAGAAGGACCAGTTCATCACCGTGCCGCGCGGCCTGGCGGACAAGGTGAAGC
CGGAAGTCGCGCTGAACGCGCCGCTCATCGCGCCGCTCGCGGACGGCCAGGCGGTCGGCTCGGTGAAGCTCGTCGCCGAC
GGCAAGACGGTGGCGGAATTCCCGGTCGTCGCGCTGCAGCCGGTGCCCGAGGCGGGCCTGCTCGGCCGCATCTGGGATTC
GATCCTGCTGATGTTCAGCAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
CGAGCCTTCGTTCCCCGACATGCCGCCGCAACGCCGCCGACCGGCCCTTCAACCGTGCGCCCCGTGCGCGCTGCAATTTC
TGCCACCAGCCTGAATCGAT

Downstream 100 bases:

>100_bases
GCTGTCCGCAAGCCCGCGGCGCCGGACACGCCGGCGCCGCGGGCTTGCGCTTTCCGTCACGATTTTCGTCATTCGTTCAA
CGCCATGAGTCAAGCCGACA

Product: D-alanyl-D-alanine carboxypeptidase family protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRLSSLGLTSLASSTAIAVAARNVALGIVLPAALVSTIAVAQAKPAAKAKHAAAPAAAAPTGAPATYAPGAVPPPGVNAR
SWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALDAKKITMEQIVTPSEAVRRVGRDESRMFIEANKPVSVHDL
VYGMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQRLGMKNTHFADVNGMPDPNHYTTAGDLATLSTHLIRDYPDYYNI
FSVKEFTYNNIKQPNRNRLLWLDPTVDGLKTGHTQAAGYCLIASAKRSLPGAADATRRLVTVMMGETKESDRVQDSMKML
NYGYTAFDSVRLYKAGQPIDTPRVYKGKSNNVQVGVKKDQFITVPRGLADKVKPEVALNAPLIAPLADGQAVGSVKLVAD
GKTVAEFPVVALQPVPEAGLLGRIWDSILLMFSKKK

Sequences:

>Translated_436_residues
MRLSSLGLTSLASSTAIAVAARNVALGIVLPAALVSTIAVAQAKPAAKAKHAAAPAAAAPTGAPATYAPGAVPPPGVNAR
SWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALDAKKITMEQIVTPSEAVRRVGRDESRMFIEANKPVSVHDL
VYGMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQRLGMKNTHFADVNGMPDPNHYTTAGDLATLSTHLIRDYPDYYNI
FSVKEFTYNNIKQPNRNRLLWLDPTVDGLKTGHTQAAGYCLIASAKRSLPGAADATRRLVTVMMGETKESDRVQDSMKML
NYGYTAFDSVRLYKAGQPIDTPRVYKGKSNNVQVGVKKDQFITVPRGLADKVKPEVALNAPLIAPLADGQAVGSVKLVAD
GKTVAEFPVVALQPVPEAGLLGRIWDSILLMFSKKK
>Mature_436_residues
MRLSSLGLTSLASSTAIAVAARNVALGIVLPAALVSTIAVAQAKPAAKAKHAAAPAAAAPTGAPATYAPGAVPPPGVNAR
SWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEALDAKKITMEQIVTPSEAVRRVGRDESRMFIEANKPVSVHDL
VYGMIIQSGNDAAIALAELVGGSEAQFVNMMNAEAQRLGMKNTHFADVNGMPDPNHYTTAGDLATLSTHLIRDYPDYYNI
FSVKEFTYNNIKQPNRNRLLWLDPTVDGLKTGHTQAAGYCLIASAKRSLPGAADATRRLVTVMMGETKESDRVQDSMKML
NYGYTAFDSVRLYKAGQPIDTPRVYKGKSNNVQVGVKKDQFITVPRGLADKVKPEVALNAPLIAPLADGQAVGSVKLVAD
GKTVAEFPVVALQPVPEAGLLGRIWDSILLMFSKKK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=379, Percent_Identity=41.9525065963061, Blast_Score=300, Evalue=9e-83,
Organism=Escherichia coli, GI1786851, Length=373, Percent_Identity=40.4825737265416, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI87082022, Length=380, Percent_Identity=39.2105263157895, Blast_Score=274, Evalue=7e-75,
Organism=Escherichia coli, GI87082054, Length=221, Percent_Identity=32.579185520362, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 46397; Mature: 46397

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSSLGLTSLASSTAIAVAARNVALGIVLPAALVSTIAVAQAKPAAKAKHAAAPAAAAP
CCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
TGAPATYAPGAVPPPGVNARSWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEAL
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
DAKKITMEQIVTPSEAVRRVGRDESRMFIEANKPVSVHDLVYGMIIQSGNDAAIALAELV
CCCHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHEEHEEECCCCHHEEHHHHH
GGSEAQFVNMMNAEAQRLGMKNTHFADVNGMPDPNHYTTAGDLATLSTHLIRDYPDYYNI
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCE
FSVKEFTYNNIKQPNRNRLLWLDPTVDGLKTGHTQAAGYCLIASAKRSLPGAADATRRLV
EEEEEHHHCCCCCCCCCEEEEECCCCCCHHCCCCCCCCEEEEEECHHCCCCHHHHHHHHH
TVMMGETKESDRVQDSMKMLNYGYTAFDSVRLYKAGQPIDTPRVYKGKSNNVQVGVKKDQ
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEECCCCCCEEEEECCCC
FITVPRGLADKVKPEVALNAPLIAPLADGQAVGSVKLVADGKTVAEFPVVALQPVPEAGL
EEECCCCCHHHCCCCEEECCCEEEECCCCCCCCEEEEEECCCCHHHCCEEEECCCCCCCH
LGRIWDSILLMFSKKK
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLSSLGLTSLASSTAIAVAARNVALGIVLPAALVSTIAVAQAKPAAKAKHAAAPAAAAP
CCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
TGAPATYAPGAVPPPGVNARSWVLVDASSNQVLASGNADERVEPASLTKLMTAYLVFEAL
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
DAKKITMEQIVTPSEAVRRVGRDESRMFIEANKPVSVHDLVYGMIIQSGNDAAIALAELV
CCCHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHEEHEEECCCCHHEEHHHHH
GGSEAQFVNMMNAEAQRLGMKNTHFADVNGMPDPNHYTTAGDLATLSTHLIRDYPDYYNI
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCE
FSVKEFTYNNIKQPNRNRLLWLDPTVDGLKTGHTQAAGYCLIASAKRSLPGAADATRRLV
EEEEEHHHCCCCCCCCCEEEEECCCCCCHHCCCCCCCCEEEEEECHHCCCCHHHHHHHHH
TVMMGETKESDRVQDSMKMLNYGYTAFDSVRLYKAGQPIDTPRVYKGKSNNVQVGVKKDQ
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEECCCCCCEEEEECCCC
FITVPRGLADKVKPEVALNAPLIAPLADGQAVGSVKLVADGKTVAEFPVVALQPVPEAGL
EEECCCCCHHHCCCCEEECCCEEEECCCCCCCCEEEEEECCCCHHHCCEEEECCCCCCCH
LGRIWDSILLMFSKKK
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]