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The map label for this gene is ctaC [H]

Identifier: 83718717

GI number: 83718717

Start: 470509

End: 472086

Strand: Direct

Name: ctaC [H]

Synonym: BTH_I0426

Alternate gene names: 83718717

Gene position: 470509-472086 (Clockwise)

Preceding gene: 83718456

Following gene: 83719643

Centisome position: 12.35

GC content: 65.91

Gene sequence:

>1578_bases
ATGGAAATTTTGGGTAAGGAAGCTATGAAAACAATCAAGCGAGCCCTCACGGGCGTGCTGGCATGCAGCGGTTTGCTCTT
GTCCGGCGCCGCTCTGGCGGTGGGCGACAGCCCGGGCGGCCCCCGCGTCAACGAGATCAATCTCCAGCAGCCCGTGACGA
AGATCGCCGAGGAGCTCTACGACCTTCACACGATGATGCTGATCCTCTGCACGGTGATCTTCGTCGGCGTGTTCGGCGTG
ATGTTCTATTCGATCTTCGCGCACCGTAAGTCGAAAGGCCACAAGGCCGCCAATTTCCACGAAAGCACCACCGTCGAAAT
CATCTGGACGATCGTGCCGTTCATCATCGTCGTGCTGATGGCGCTGCCCGCCACGAAGGCCGTCGTCGCGATGAAGGACA
CGACGAACGCCGATCTCACGGTCAAGGTCACCGGCTACCAGTGGAAGTGGGGCTACGACTACGTGAAGGGCCCGGGCGAA
GGCATCAGCTTCCTGTCCACGCTGTCGACGCCGCGCGCCGAAGTGAACGGCCAGCAGCCGATCAGCGACACCTATCTGCA
GGAAGTCGATCACCCGCTCGTCGTGCCGGTCAACAAGAAGATCCGCGTGATCACGACCGCGAACGACGTCGTCCACTCGT
GGTACGTGCCCGCGTTCGGCGTGAAGCAGGACGCGATTCCGGGCTTCGTGCGCGATACCTGGTTCAAGGCCGATAAGGTC
GGCACCTACCGCGGCTTCTGCACGGAGCTCTGCGGCAAGGAGCACGCGTACATGCCGGTCGTCGTCGAGGTGCTGTCGGA
CGACGACTACGCGAAGTGGGTGAGCGCGCAGAAGGCGAAGCTCGCCGCGGGCGCGGTCGATCCGAACAAGGTATATACGC
GCGCCGAACTGATGGCGCACGGCGAGGAAGTCTACAAGGCGAACTGCGCGGTGTGCCACCAGCCGAACGGCAAGGGCGTC
GGCGCGTTCCCCGCGCTCGACGGCGGCAAGATCGTCAACGGCCCGATCGCGGGCCACCTCGAGCAGGTGCTCAAGGGCAA
GGGCGCGATGCCGTCGTGGGCGTCGCTGTCGGATCTCGACATCGCGTCGGTGATCACGTACGAGCGCAACTCGTGGGGCA
ATCACAAGGGCGATTCGCTGCAGCCGAAGCAGGTGGCCGACGCGCGCAACGGCAAGCTGCCGGCTGACGCGCAGCAGGCG
GACGGCGGCGCGGCGGCGCCGGCGGCGGATGCCTCGGGCGCGGCCGCGCAGACGCAGGCACGGACGCTGCCGGCGGCAAT
CTATTTCGAGACGGGCAAGAGCGAGCTGCCGGCGGACGCGAAGGACGCGATCGCCGCGGCGGCCGAATACGTGAAGGCGC
ATCCGGACGCGAAGCTCGCGTTGTCGGGCTTCACCGACAAGACGGGCTCGGCCGACGCGAACGCCGCACTGGCCAAGCGC
CGCGCGCAGATCGTGCGCGATGCGCTGAAGACGGCCGGCGTTGCAGAGGACCGCATCATTCTGAAGAAGCCGGAAACGAT
CACGGGCGGGGCGGACGCGAAGGAAGCCCGGCGGGTCGAGATCGGCCCGGCGGCTTGA

Upstream 100 bases:

>100_bases
CGCGCGCAGTTCGCGCGCGAGCTGCGCGCCTCGCTTTCGCGCTGCGGCTGAACGAGGCGGCGGGCGTGACGCGGGCGGCC
TGCGACGGGGGAGGGTTTGA

Downstream 100 bases:

>100_bases
CGTGTCGCTGTGTTTGTCGACGTATTCGCATTAGGAGATTCTCATGTCTAGCATCGGGCACGACGTAGCCGCGGGCCACG
CGCACGACGACCACGCGCAC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MEILGKEAMKTIKRALTGVLACSGLLLSGAALAVGDSPGGPRVNEINLQQPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRAEVNGQQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAVCHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPADAQQA
DGGAAAPAADASGAAAQTQARTLPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAALAKR
RAQIVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Sequences:

>Translated_525_residues
MEILGKEAMKTIKRALTGVLACSGLLLSGAALAVGDSPGGPRVNEINLQQPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRAEVNGQQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAVCHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPADAQQA
DGGAAAPAADASGAAAQTQARTLPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAALAKR
RAQIVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
>Mature_525_residues
MEILGKEAMKTIKRALTGVLACSGLLLSGAALAVGDSPGGPRVNEINLQQPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGE
GISFLSTLSTPRAEVNGQQPISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAAGAVDPNKVYTRAELMAHGEEVYKANCAVCHQPNGKGV
GAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLDIASVITYERNSWGNHKGDSLQPKQVADARNGKLPADAQQA
DGGAAAPAADASGAAAQTQARTLPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAALAKR
RAQIVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=34.841628959276, Blast_Score=138, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=233, Percent_Identity=30.9012875536481, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 55848; Mature: 55848

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILGKEAMKTIKRALTGVLACSGLLLSGAALAVGDSPGGPRVNEINLQQPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGEGISFLSTLSTPRAEVNGQQP
HCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHCCCCCC
ISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAAGAVDPNKVYTRAELMAH
CCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
GEEVYKANCAVCHQPNGKGVGAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLD
CHHHHHCCCEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC
IASVITYERNSWGNHKGDSLQPKQVADARNGKLPADAQQADGGAAAPAADASGAAAQTQA
HHHHEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
RTLPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAALAKR
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHH
RAQIVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MEILGKEAMKTIKRALTGVLACSGLLLSGAALAVGDSPGGPRVNEINLQQPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTVKVTGYQWKWGYDYVKGPGEGISFLSTLSTPRAEVNGQQP
HCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHCCCCCC
ISDTYLQEVDHPLVVPVNKKIRVITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTYRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAAGAVDPNKVYTRAELMAH
CCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
GEEVYKANCAVCHQPNGKGVGAFPALDGGKIVNGPIAGHLEQVLKGKGAMPSWASLSDLD
CHHHHHCCCEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC
IASVITYERNSWGNHKGDSLQPKQVADARNGKLPADAQQADGGAAAPAADASGAAAQTQA
HHHHEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
RTLPAAIYFETGKSELPADAKDAIAAAAEYVKAHPDAKLALSGFTDKTGSADANAALAKR
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHH
RAQIVRDALKTAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]