Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 83718610

GI number: 83718610

Start: 2401485

End: 2403383

Strand: Direct

Name: ppiD [H]

Synonym: BTH_I2129

Alternate gene names: 83718610

Gene position: 2401485-2403383 (Clockwise)

Preceding gene: 83719546

Following gene: 83720058

Centisome position: 63.04

GC content: 67.19

Gene sequence:

>1899_bases
ATGTTCTTCCTGCTCCTGATCGTGCTGCCGGGGCTTGGGATCGTCGGCATTCAGGGTTTCCGTGGGTTCTTCGACGAAAG
CGCGAACGTCGCGGCCGTCAACGGGCACAAGATCACGCGCGCCGAATTCGACGGCATGCTGCGCCAGCAGGTCGACCAGG
CGCGCCAGATGCTGGGCGCGCAGTTCGACGCGAAGGCGTTCGATACGCCGGAGCGCCGCCAGCAACTTCTCGACGGGCTG
ATCCAGCAGCGCGCGCTCGCCGACGAGACGCAGCGCCTGCATCTGACCGCGTCGGACGGCGCGGTGCGCCAGACGCTGTT
GAGCGATCCGGTGGTCGCGTCGCTGAAGAAGGCGGACGGCTCGTTCGACGCCGAGCGCTACACGCAGATGCTCGCGATGC
AGGGCATGACGCCCGATCAATACCAGGAGCGCGTGCGCTACAACCTCGCGCTGCAGCAGATTCCCGCCAGCATCGTGTCG
AGCGCGTTCACGCCGAAGAGCGTCGCGCGCCGCCTGACCGAACTCGCCGAGCAGCAGCGCGAAGTGCAGCAGATGATGCT
GAAGTCGGCCGATTACGCGACGAAGGTGCAGCCGACTGACGCGCAGATTTCCGCCTACTACGATGCGCACAAGCAGGCGT
TCGCGACGCGCGAGGCGGCGACGATCCAGTATCTCGTCTATTCGCAGGCGGCCGCCGCCGCGGCGGCGCAGCCGAGCGAC
ATTGACGTCAAGAAATACTACGACGGCAACATCGCGCGCTACCGCACCGACGCGCAGGTGCGCGTGAGCCACATCTTCAT
CGCCGCGGCGAAGGATGCGAGCGCGGCCGACAAGGCCGCCGCGAAGGCGAAAGCGGAGCAACTGCTCGCCGAGGTGAAGG
CGCATCCGGACCAGTTCGCGCAGATCGCCGAGAAGAACTCGCAGGACGCGCCGTCGGCGGCGAAGGGCGGCGACCTCGGC
TTCATCACGCGCGGCTCGACCGCGGGCGGCGCCGCGTTCGACGATGCCGCGTTTGCGCTGAAGAAGGGCGAAATCAGCGG
CGTCGTGCAGGGCGACTTCGGCTTTCACATCCTGAAGGCGACCGATCTGAAGCCGGCAGTCGTGAAGCCGCTCGCGGAGG
TGAAGGATTCGATCGTGGCGGACCTGAAGCAGCAGTTCGCGGCCAAGGCGTTCGCCGACAATGCGGAGGGCTTCACGTCG
ACCGTCTACGAGAAGGCGAAGAGCCTGCAGCCCGCCGCCGACAAGTACACGCTGACGATCCAGACCGCGACGGTGTCGCC
GCAACCGAATCCGGCGCTGCCGCCCGATAGCCCGCTCAACAACGCGAAATTCCTCGCGGCCGTGTTCGCCGCCGATGCGG
TGAAGAACGGCAACAACACGCAGGCGATCGATGTCGGCAACAACACGCTGATCGCCGCGCGCGTGACGAGTTACCAGCCG
TCGACCGTGCCCGCGCTCGATGCGATCAAGGATCAGGTGCGCGCGAAGGTGGTCGCCGACGAGGCGGCGCGTCTCGCGAA
GCAGGATGGCGAGGCGAAGCTCGCGGAACTGCGCAAGTCGAAGTCGACGGCGGGCTTCGCCGCAGCCGACAAGATCTCGC
GCACGCAGGCGCACGGCCTGCCGCCCGCGGCCGTCAGCGCGATCTACAAGGTCGATCCGAAGACGCTGCCCGCCTATGTC
GGCGTCGATCTCGGCAACGACGGCTACGCGATTTTCCGCGTGAATTCGGTGGTCGCGGCGGCGCCTGCCGACGATCAGCG
CCTCGCGGCCGCCCAGCAGCAGCTCGCGCAGGTGTATGCGCAAAGCGAGACGGAAGCGTATCTCGCGTCGCTGCGCGCGC
GCTCGAAGGTCAAGCTGTATGGCTCGACCGCCGGCGGCGCGCAGGACGGTTCGAACTGA

Upstream 100 bases:

>100_bases
GTTCGCCTTTTTTCTTGCCCGCTGTTGTAATATCGGGCGTTTTGTCCAGCTCACGCCGTCACGCATGCTCGATTTCTTTC
GCAATCACCAGCGCCTGATG

Downstream 100 bases:

>100_bases
CGGCATGCGACGGCGCGCCAGCGCGCCCGTTCGACAAAAACAGCCCCGCCATCGTGCGGGGCTGTTTCGTTTCGGCTGGC
GGGGTTGCGCGCCGGAGAGG

Product: peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGMLRQQVDQARQMLGAQFDAKAFDTPERRQQLLDGL
IQQRALADETQRLHLTASDGAVRQTLLSDPVVASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVS
SAFTPKSVARRLTELAEQQREVQQMMLKSADYATKVQPTDAQISAYYDAHKQAFATREAATIQYLVYSQAAAAAAAQPSD
IDVKKYYDGNIARYRTDAQVRVSHIFIAAAKDASAADKAAAKAKAEQLLAEVKAHPDQFAQIAEKNSQDAPSAAKGGDLG
FITRGSTAGGAAFDDAAFALKKGEISGVVQGDFGFHILKATDLKPAVVKPLAEVKDSIVADLKQQFAAKAFADNAEGFTS
TVYEKAKSLQPAADKYTLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADAVKNGNNTQAIDVGNNTLIAARVTSYQP
STVPALDAIKDQVRAKVVADEAARLAKQDGEAKLAELRKSKSTAGFAAADKISRTQAHGLPPAAVSAIYKVDPKTLPAYV
GVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETEAYLASLRARSKVKLYGSTAGGAQDGSN

Sequences:

>Translated_632_residues
MFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGMLRQQVDQARQMLGAQFDAKAFDTPERRQQLLDGL
IQQRALADETQRLHLTASDGAVRQTLLSDPVVASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVS
SAFTPKSVARRLTELAEQQREVQQMMLKSADYATKVQPTDAQISAYYDAHKQAFATREAATIQYLVYSQAAAAAAAQPSD
IDVKKYYDGNIARYRTDAQVRVSHIFIAAAKDASAADKAAAKAKAEQLLAEVKAHPDQFAQIAEKNSQDAPSAAKGGDLG
FITRGSTAGGAAFDDAAFALKKGEISGVVQGDFGFHILKATDLKPAVVKPLAEVKDSIVADLKQQFAAKAFADNAEGFTS
TVYEKAKSLQPAADKYTLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADAVKNGNNTQAIDVGNNTLIAARVTSYQP
STVPALDAIKDQVRAKVVADEAARLAKQDGEAKLAELRKSKSTAGFAAADKISRTQAHGLPPAAVSAIYKVDPKTLPAYV
GVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETEAYLASLRARSKVKLYGSTAGGAQDGSN
>Mature_632_residues
MFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGMLRQQVDQARQMLGAQFDAKAFDTPERRQQLLDGL
IQQRALADETQRLHLTASDGAVRQTLLSDPVVASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVS
SAFTPKSVARRLTELAEQQREVQQMMLKSADYATKVQPTDAQISAYYDAHKQAFATREAATIQYLVYSQAAAAAAAQPSD
IDVKKYYDGNIARYRTDAQVRVSHIFIAAAKDASAADKAAAKAKAEQLLAEVKAHPDQFAQIAEKNSQDAPSAAKGGDLG
FITRGSTAGGAAFDDAAFALKKGEISGVVQGDFGFHILKATDLKPAVVKPLAEVKDSIVADLKQQFAAKAFADNAEGFTS
TVYEKAKSLQPAADKYTLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADAVKNGNNTQAIDVGNNTLIAARVTSYQP
STVPALDAIKDQVRAKVVADEAARLAKQDGEAKLAELRKSKSTAGFAAADKISRTQAHGLPPAAVSAIYKVDPKTLPAYV
GVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETEAYLASLRARSKVKLYGSTAGGAQDGSN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=638, Percent_Identity=28.5266457680251, Blast_Score=185, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67408; Mature: 67408

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGMLRQQVDQARQMLGA
CHHHHHHHHCCCCEEECCHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC
QFDAKAFDTPERRQQLLDGLIQQRALADETQRLHLTASDGAVRQTLLSDPVVASLKKADG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCC
SFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVSSAFTPKSVARRLTELAEQQR
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVQQMMLKSADYATKVQPTDAQISAYYDAHKQAFATREAATIQYLVYSQAAAAAAAQPSD
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IDVKKYYDGNIARYRTDAQVRVSHIFIAAAKDASAADKAAAKAKAEQLLAEVKAHPDQFA
CCCCEECCCCEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QIAEKNSQDAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKGEISGVVQGDFGFHILKA
HHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEE
TDLKPAVVKPLAEVKDSIVADLKQQFAAKAFADNAEGFTSTVYEKAKSLQPAADKYTLTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEE
QTATVSPQPNPALPPDSPLNNAKFLAAVFAADAVKNGNNTQAIDVGNNTLIAARVTSYQP
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCC
STVPALDAIKDQVRAKVVADEAARLAKQDGEAKLAELRKSKSTAGFAAADKISRTQAHGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
PPAAVSAIYKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYA
CHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHH
QSETEAYLASLRARSKVKLYGSTAGGAQDGSN
HCHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGMLRQQVDQARQMLGA
CHHHHHHHHCCCCEEECCHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC
QFDAKAFDTPERRQQLLDGLIQQRALADETQRLHLTASDGAVRQTLLSDPVVASLKKADG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCC
SFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVSSAFTPKSVARRLTELAEQQR
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVQQMMLKSADYATKVQPTDAQISAYYDAHKQAFATREAATIQYLVYSQAAAAAAAQPSD
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IDVKKYYDGNIARYRTDAQVRVSHIFIAAAKDASAADKAAAKAKAEQLLAEVKAHPDQFA
CCCCEECCCCEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QIAEKNSQDAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKGEISGVVQGDFGFHILKA
HHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEE
TDLKPAVVKPLAEVKDSIVADLKQQFAAKAFADNAEGFTSTVYEKAKSLQPAADKYTLTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEE
QTATVSPQPNPALPPDSPLNNAKFLAAVFAADAVKNGNNTQAIDVGNNTLIAARVTSYQP
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCC
STVPALDAIKDQVRAKVVADEAARLAKQDGEAKLAELRKSKSTAGFAAADKISRTQAHGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
PPAAVSAIYKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYA
CHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHH
QSETEAYLASLRARSKVKLYGSTAGGAQDGSN
HCHHHHHHHHHHCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]