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The map label for this gene is apaH [H]

Identifier: 83718600

GI number: 83718600

Start: 1663478

End: 1664326

Strand: Reverse

Name: apaH [H]

Synonym: BTH_I1468

Alternate gene names: 83718600

Gene position: 1664326-1663478 (Counterclockwise)

Preceding gene: 83720850

Following gene: 83719524

Centisome position: 43.69

GC content: 69.73

Gene sequence:

>849_bases
ATGACAAATTTCTCCAGCAGCCCGCCGATCGCTTTCGGCGACCTCCAAGGCTGCCACGCCGCGTATCGGCAGCTCTTCGC
CCAGCTCTCGCCGGCGGCCGACACCCCGCTCTGGTTCGCGGGCGACCTCGTCAACCGGGGCCCCGCGTCGCTCGCGACGC
TGCGCGAGATCGTCGGGCTCGGCGAACGCGCGGTCGCCGTGCTCGGCAATCACGATCTGCACCTGCTCGCGGTCGCGGCC
GGGATTCGCACACTGAAGCCGGGCGACACGATCGGCGAGATCCTCGACGCGCCCGACGCCGACGATCTGATCGAGTGGGT
GCGCCACCGGCCGTTCGCGCACTTCGAGCGCGGCATGCTGATGGTGCACGCGGGCCTGCTGCCGCAATGGGACGCGGCGC
TCGCGCTCGAGCTCGCCGACGAATTGCAGCGCGCGCTGCGCGCGCCGAACTGGCGCGACACGTTGCGCGGCCTGTACGGC
AACGACCCCAATTGCTGGAGCCCTGATCTGAAGAAAGCGGACCGGCTGAGGGTCGCGTTCAACGCGTTCACGCGCATTCG
CTTCTGCACGCCGGAAGGCGCAATGGAATTTCGGGCGAACGGCGGTCCGGCGTCCGCGCCTGCCGGCTACCTGCCGTGGT
TCGACGCGCCCAGCCGAAAAACCGCTGACGTGACGGTCGTGTTCGGTCACTGGGCCGCGTTGGGGCTGATGCTGCGCGAG
AACCTGGTCGCGCTGGATTCGGGATGCGTATGGGGCAATCGGCTGTCGGCCGTGCGGCTCGCCGACGATCCGGCCGCGCG
CGAAGTCGCGCAGGTCGCATGCGAGCGCTGCGGGGCGGCGGAAGAATAG

Upstream 100 bases:

>100_bases
GAGACCGATGCCGGATCGAATTTTATCCATCGCCGATCCGCTCGGATCGATGTGGTTTCTTGTGATACCGTGAACTCGGT
TTCGTCACGAATGCAAAGGA

Downstream 100 bases:

>100_bases
CCGCGCGGGCGGGTGCGCCCGACACATGCCTGCCTCGCCCGCATCCGCCCGCACGCGTTTGAAGTGCGCGCCGGCCGACG
TGTCGGCGTGCGCCGCAACT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTNFSSSPPIAFGDLQGCHAAYRQLFAQLSPAADTPLWFAGDLVNRGPASLATLREIVGLGERAVAVLGNHDLHLLAVAA
GIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRGLYG
NDPNCWSPDLKKADRLRVAFNAFTRIRFCTPEGAMEFRANGGPASAPAGYLPWFDAPSRKTADVTVVFGHWAALGLMLRE
NLVALDSGCVWGNRLSAVRLADDPAAREVAQVACERCGAAEE

Sequences:

>Translated_282_residues
MTNFSSSPPIAFGDLQGCHAAYRQLFAQLSPAADTPLWFAGDLVNRGPASLATLREIVGLGERAVAVLGNHDLHLLAVAA
GIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRGLYG
NDPNCWSPDLKKADRLRVAFNAFTRIRFCTPEGAMEFRANGGPASAPAGYLPWFDAPSRKTADVTVVFGHWAALGLMLRE
NLVALDSGCVWGNRLSAVRLADDPAAREVAQVACERCGAAEE
>Mature_281_residues
TNFSSSPPIAFGDLQGCHAAYRQLFAQLSPAADTPLWFAGDLVNRGPASLATLREIVGLGERAVAVLGNHDLHLLAVAAG
IRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRGLYGN
DPNCWSPDLKKADRLRVAFNAFTRIRFCTPEGAMEFRANGGPASAPAGYLPWFDAPSRKTADVTVVFGHWAALGLMLREN
LVALDSGCVWGNRLSAVRLADDPAAREVAQVACERCGAAEE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=256, Percent_Identity=43.75, Blast_Score=215, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30602; Mature: 30471

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFSSSPPIAFGDLQGCHAAYRQLFAQLSPAADTPLWFAGDLVNRGPASLATLREIVGL
CCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHCCCCHHHHHHHHHHCC
GERAVAVLGNHDLHLLAVAAGIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGML
CCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHCCEE
MVHAGLLPQWDAALALELADELQRALRAPNWRDTLRGLYGNDPNCWSPDLKKADRLRVAF
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NAFTRIRFCTPEGAMEFRANGGPASAPAGYLPWFDAPSRKTADVTVVFGHWAALGLMLRE
HHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
NLVALDSGCVWGNRLSAVRLADDPAAREVAQVACERCGAAEE
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNFSSSPPIAFGDLQGCHAAYRQLFAQLSPAADTPLWFAGDLVNRGPASLATLREIVGL
CCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHCCCCHHHHHHHHHHCC
GERAVAVLGNHDLHLLAVAAGIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGML
CCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHCCEE
MVHAGLLPQWDAALALELADELQRALRAPNWRDTLRGLYGNDPNCWSPDLKKADRLRVAF
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NAFTRIRFCTPEGAMEFRANGGPASAPAGYLPWFDAPSRKTADVTVVFGHWAALGLMLRE
HHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
NLVALDSGCVWGNRLSAVRLADDPAAREVAQVACERCGAAEE
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA