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The map label for this gene is ubiB [H]

Identifier: 83718588

GI number: 83718588

Start: 633605

End: 635182

Strand: Direct

Name: ubiB [H]

Synonym: BTH_I0556

Alternate gene names: 83718588

Gene position: 633605-635182 (Clockwise)

Preceding gene: 83721316

Following gene: 83719252

Centisome position: 16.63

GC content: 65.97

Gene sequence:

>1578_bases
ATGCGCATTTTCCGTTTCGTCAAAATCGTCTTTACCGTCATCCGCTTCGGCCTCGACGAGGTGATGCTGTCGCGCATCGA
AAACCCTCGCGTGAAGTTCCTGTTGCGCATCACGACGATCGGCCGGCGCTTCGCCGATCCGCCCGCGGTGCGGCTGCGCC
GCGCGCTAGAGAGCCTCGGGCCGATCTTCGTGAAGTTCGGCCAGGTGCTGTCGACGCGGCGCGATCTGCTGCCCGTCGAT
TTCGCGAACGAGCTCGCGAAGCTGCAGGATCAGGTGCCGCCGTTCGATTCGGCCGTTGCGATCGCGATCGTCGAGAAGTC
GCTCGGCGCGCGCATCGACGAGCTGTTCGACGAGTTCGAGCGCGAGCCCGTCGCGAGCGCGTCGATCGCGCAGGTGCACT
TCGCGAAGCTCAAGCAGGGCGAGCACAAGGGCAAGGCGGTCGCGGTCAAGGTGCTGCGGCCGAACATGCTGCCCGTTATC
GATTCCGATCTCGCGCTGATGCGCGACATCGCGACCTGGGCCGAGCGCCTGTGGGCGGATGGCCGGCGGCTCAAGCCGCG
CGAGGTCGTCGCCGAATTCGACAAGTACCTGCACGACGAGCTCGACCTGATGCGCGAGGCGGCGAATGGCAGCCAGTTGC
GCCGCAACTTCGCGGGGCTCGATCTGCTGCTCGTGCCGGAAATGTTCTGGGATTACTCGACGCCCTCCGTGCTCGTGATG
GAGCGGATGACGGGCGTGCCGATCAGCCAGGTGGACACGCTGCGCGCCGCGGGCGTCGACATTCCGAAGCTCGCGCGCGA
AGGCGTCGAGATCTTCTTCACGCAAGTGTTCCGCGACGGCTTCTTCCACGCGGACATGCACCCGGGCAATATCCAGGTGA
GCCTCGATCCGAAGCACTTCGGGCGCTACATCGCGCTCGACTTCGGGATCGTCGGCGCGCTGTCGGATTTCGACAAGAAC
TACCTCGCGCAAAACTTCCTCGCGTTCTTCAAGCGCGACTATCACCGCGTCGCGACGCTGCACCTCGAATCCGGCTGGGT
GCCGCCCGACACGCGCGTCGAGGAGCTCGAAAGCGCGATCCGCGCGGTTTGCGAGCCGTACTTCGACCGCGCGCTGAAGG
ATATCTCGCTCGGCCAGGTGCTGATGCGGCTGTTCTCGACGTCGCGCCGCTTCAACGTCGAGATCCAGCCGCAGCTCGTG
CTCCTGCAGAAGACGATGCTGAACGTCGAGGGGCTCGGCCGCTCGCTCGATCCCGAGCTCGACCTGTGGAAGACCGCGAA
ACCGTACCTCGAGCGCTGGATGGCCGAGCAGATCGGGCTGCGCGGCTGGTACGAGCGCTTCAAGGTCGAGGCGCCGCAAT
GGAGCAAGACGCTGCCGCAACTGCCGCGCCTCGTGCATCAGGCGCTCCTCTCGCATCATGAGGCGCCGCGCGCGATCAGC
GACGACCTGATCCGGCAGATTCTCGTCGAGCAGAGGCGGACCAACCGGCTGCTGCAGGCGCTGCTCGTGTTCGGGCTCGC
GGTCGGCGCGGGCGCGGTGATCGCGCGGGTGCTGATCGTCATCGCGTACGGTGGGTGA

Upstream 100 bases:

>100_bases
CGCGCTTGCGCGCGTCGAGAAACGGATCGAACGACTGGAGCAAAAAATCGACGCGCGCGCGGGCGGCAGCTCGCGACGCG
TGCAGTGAGGGCCGCGAGGC

Downstream 100 bases:

>100_bases
GGCCGCGGCCGGGCTCGCGGCGGAGCGTGCGACACGGCGCGCGAGGCACGCGCGGATCGGCGGGCGGATGCGCTCGGCGG
GCGGCGCAGCCTGCGGACGA

Product: ubiquinone biosynthesis protein UbiB

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKFLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDELFDEFEREPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPSVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALLSHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVIAYGG

Sequences:

>Translated_525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKFLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDELFDEFEREPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPSVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALLSHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVIAYGG
>Mature_525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKFLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDELFDEFEREPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPSVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALLSHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVIAYGG

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=314, Percent_Identity=29.2993630573248, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI40254938, Length=262, Percent_Identity=31.2977099236641, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI217035081, Length=217, Percent_Identity=31.7972350230415, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI32261307, Length=319, Percent_Identity=28.8401253918495, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI34147522, Length=211, Percent_Identity=29.8578199052133, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367309, Length=521, Percent_Identity=49.1362763915547, Blast_Score=493, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=30.7142857142857, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6325148, Length=440, Percent_Identity=26.8181818181818, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=250, Percent_Identity=28.4, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=236, Percent_Identity=26.6949152542373, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI22024280, Length=272, Percent_Identity=31.9852941176471, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24662575, Length=269, Percent_Identity=31.9702602230483, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 59856; Mature: 59856

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKFLLRITTIGRRFADPPAVRLRRALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDELFDEFE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
REPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWAD
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPSVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEHHHHHHCCCCCHHHHH
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALLSHHEAPRAIS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVIAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKFLLRITTIGRRFADPPAVRLRRALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDELFDEFE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
REPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWAD
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPSVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEHHHHHHCCCCCHHHHH
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMAEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALLSHHEAPRAIS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVIAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA