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The map label for this gene is recQ [H]

Identifier: 83718492

GI number: 83718492

Start: 3506846

End: 3508780

Strand: Reverse

Name: recQ [H]

Synonym: BTH_I3074

Alternate gene names: 83718492

Gene position: 3508780-3506846 (Counterclockwise)

Preceding gene: 83719751

Following gene: 83719839

Centisome position: 92.11

GC content: 67.29

Gene sequence:

>1935_bases
GTGCGACCTTCGTCCACCTTTCGCGGCGGCGACGTTGGTAAAATCCCGCCCACCGGCTCCTTTCGCAGTCCATCCATCTC
CAGACCCATGTCCCGCGCGCTCGAAATTCTCAACGAAGTCTTCGGCTATCCCGCCTTCCGAGGTCAACAGGGCGAGATCG
TCGAGCACGTTGCGGCGGGCGGCGACTGCCTCGTGCTGATGCCCACGGGCGGCGGCAAGTCGCTCTGCTACCAGATCCCG
GCGCTCGTGCGCAGCGAGTCGGGCCGCGGCGCGGGCATCGTCGTGTCGCCGCTCATCGCGCTGATGCAGGATCAGGTCGC
CGCGCTGTCCGAAGTCGGCGTGCGCGCGGCGTATCTGAACTCGACGCTGTCGGGCGCCGAGGCGGCCGCGACCGAACGCG
CGCTGCGCGACGGCGACATCGATCTGCTCTACGTCGCGCCCGAGCGATTGATGACGCCGCGTTTTCTCGATCTGCTCGAG
CGCGCGCGCATCGGCCTTTTCGCGATAGACGAGGCGCACTGCGTGTCGCAGTGGGGTCACGATTTCCGGCCCGAGTACAT
TCAGTTGTCGGTGCTGCACGAGCGCTTTCCGGACGTGCCGCGAATCGCGCTGACCGCGACCGCCGACGCGATCACGCGCG
ACGAGATCGTTCAGCGGCTCGCGCTCGACGACGCGCGCATCTTCGTGTCGAGCTTCGACCGGCCGAACATCCGCTATCGG
ATCGTCGAAAAGGACAACGCGCGCTCGCAATTGCTCGATTTCATTCGCGCGGAGCACACGAACGCGGACGGCACGACCGA
TGCGGGCGTCGTCTATTGTCTGTCGCGCCGCAAGGTCGAGGAGACGGCCGAGTGGTTGAAGGCGCAGGGGGTGCGTGCGC
TGCCGTATCACGCGGGAATGGAGTTCGAAATCCGGCAGAAGCACCAGGAGATGTTCCAGCGCGAGGAGGGGATCGTGATG
TGCGCGACGATCGCGTTCGGCATGGGCATCGACAAGCCGGATGTGCGCTTCGTCGCGCACCTGGATTTGCCGAAAAGCGT
CGAAGGCTACTACCAGGAGACCGGGCGCGCGGGCCGCGACGGCATGCCGGCGAATGCGTGGATGGCGTATGGGCTCGGCG
ATGTCGTTCAGCAGCGCAAGATGATTGACGAATCGGATGCCGACGACACGCACAAGCGCGTTCAGACGTCGAAGCTCGAC
GCGCTGCTCGGGCTGTGCGAGACGGCATCGTGCCGCCGGGTGCGCCTCCTTGCGTACTTCGGCGAGACGAGCGGCCCGTG
CGGCAATTGCGACACCTGCCTCGAGCCGCCGGCGACATGGGACGCGACGCGTGAGGCGCAGATGGCGCTGTCGTGCGTGT
TCCGCGCGCAGCGCGCGAGCGGCTTCAATTTCGGCGCGAGCCACCTGATCGAAGTGCTGCGTGGCGGGCGTACCGAAAAG
GTGCTGCAGCGCGGTCACGAGAGTCTCAGCACGTTCGGCATCGGCGCCGAACTGTCCGAAGCCGAATGGCGGGCGATCTT
CCGGCAGCTCGTCGCGTTCGGTTATCTCGCCGTCGATCACGGCGGCTTCGGCGCACTCGTGCTGACGGAAGCGAGCAAGC
CGGTGCTCAAGGGCGAGGAGAAGGTCACGCTGCGCCGCTACGTGAAGCCGGCGCGCACCCGGCAATCGTCCGGCCGCAGC
GGCGCGCGCGTCGATCCGACGGCCGGCATGAGCGCGCGCGAGCGCGCGTGCTGGGAGCGCTTGCGCGCATGGCGCGCGGA
AACGGCGAAGAGCGACGGCGTGCCCGCGTACGTGATCTTCCATGACGCGACGCTCGCGGAGATCGCCCGCAACGCGCCGG
AATCGATCGACGACTTGCGCCATATCCCCGGAATCGGCGCGCGCAAGCTGGACCGCTTCGGCGACGAGATTCTCGAGGTC
GTCGAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCTTTGCCTGCCCGCCGAGGAAGCCGCCCGGTTTCGACCGGGCGGCTTTTTTTATGCGCGTGCCGCGCGGCGCGGCCGC
GAGCCGGCTGAACGGGCAAC

Downstream 100 bases:

>100_bases
GCGGGCTGCTCGCCTTCGCATTCCGGCACCAAAAATCACGCAAGCTGTTGACTCACTTGGGATTTTCGGAATATCATGCC
GGGTTCCGGTTCTCGGTGGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MRPSSTFRGGDVGKIPPTGSFRSPSISRPMSRALEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSESGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGIVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGGRTEK
VLQRGHESLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VEAA

Sequences:

>Translated_644_residues
MRPSSTFRGGDVGKIPPTGSFRSPSISRPMSRALEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSESGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGIVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGGRTEK
VLQRGHESLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VEAA
>Mature_644_residues
MRPSSTFRGGDVGKIPPTGSFRSPSISRPMSRALEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSESGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGIVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGGRTEK
VLQRGHESLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VEAA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=663, Percent_Identity=34.5399698340875, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI14591902, Length=419, Percent_Identity=37.4701670644391, Blast_Score=285, Evalue=7e-77,
Organism=Homo sapiens, GI14591904, Length=419, Percent_Identity=37.4701670644391, Blast_Score=285, Evalue=7e-77,
Organism=Homo sapiens, GI148612816, Length=477, Percent_Identity=37.7358490566038, Blast_Score=270, Evalue=4e-72,
Organism=Homo sapiens, GI169218196, Length=604, Percent_Identity=31.2913907284768, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI110735439, Length=604, Percent_Identity=31.2913907284768, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI51242947, Length=402, Percent_Identity=39.8009950248756, Blast_Score=252, Evalue=8e-67,
Organism=Homo sapiens, GI51242943, Length=402, Percent_Identity=39.8009950248756, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=36.5994236311239, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI148613856, Length=400, Percent_Identity=25.5, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38201710, Length=400, Percent_Identity=25.5, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4758138, Length=346, Percent_Identity=25.1445086705202, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI301171467, Length=334, Percent_Identity=24.5508982035928, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI48994977, Length=618, Percent_Identity=44.4983818770227, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=24.2774566473988, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=663, Percent_Identity=34.9924585218703, Blast_Score=338, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI71987997, Length=412, Percent_Identity=40.0485436893204, Blast_Score=298, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=412, Percent_Identity=40.0485436893204, Blast_Score=298, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=698, Percent_Identity=30.0859598853868, Blast_Score=286, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=448, Percent_Identity=36.6071428571429, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17510309, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995514, Length=325, Percent_Identity=25.5384615384615, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995718, Length=336, Percent_Identity=23.5119047619048, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71987143, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=349, Percent_Identity=24.0687679083095, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.239852398524, Blast_Score=350, Evalue=4e-97,
Organism=Saccharomyces cerevisiae, GI6325138, Length=335, Percent_Identity=25.0746268656716, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=640, Percent_Identity=36.5625, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24664226, Length=456, Percent_Identity=37.0614035087719, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24664230, Length=434, Percent_Identity=37.7880184331797, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI62472181, Length=434, Percent_Identity=37.7880184331797, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI21358123, Length=370, Percent_Identity=34.0540540540541, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI28574962, Length=364, Percent_Identity=23.6263736263736, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18857967, Length=347, Percent_Identity=22.7665706051873, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70873; Mature: 70873

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSSTFRGGDVGKIPPTGSFRSPSISRPMSRALEILNEVFGYPAFRGQQGEIVEHVAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
GDCLVLMPTGGGKSLCYQIPALVRSESGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLN
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGH
HHCCCHHHHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHHCCCEEEECHHHHHHHCCC
DFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
CCCCCCEEEHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGM
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
EFEIRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRD
CHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
GMPANAWMAYGLGDVVQQRKMIDESDADDTHKRVQTSKLDALLGLCETASCRRVRLLAYF
CCCCHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGGRTEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHH
VLQRGHESLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCH
KVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIF
HHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
HDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVEAA
ECCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPSSTFRGGDVGKIPPTGSFRSPSISRPMSRALEILNEVFGYPAFRGQQGEIVEHVAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
GDCLVLMPTGGGKSLCYQIPALVRSESGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLN
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGH
HHCCCHHHHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHHCCCEEEECHHHHHHHCCC
DFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
CCCCCCEEEHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGM
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
EFEIRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRD
CHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
GMPANAWMAYGLGDVVQQRKMIDESDADDTHKRVQTSKLDALLGLCETASCRRVRLLAYF
CCCCHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGGRTEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHH
VLQRGHESLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCH
KVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIF
HHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
HDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVEAA
ECCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]