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The map label for this gene is tauD [C]

Identifier: 83718402

GI number: 83718402

Start: 2220411

End: 2221289

Strand: Direct

Name: tauD [C]

Synonym: BTH_I1958

Alternate gene names: 83718402

Gene position: 2220411-2221289 (Clockwise)

Preceding gene: 83721588

Following gene: 83721473

Centisome position: 58.29

GC content: 68.15

Gene sequence:

>879_bases
ATGGAAACACTGGAGATTCGGCCGCTGAGCGGGACCATCGGCGCGCAGGTGCGCAACCGCACGCTCGCCGGCGTCGTCGA
AAGCGGGCGTGTCGACGAGATCCGGCAGGCGCTGCTGCGATACAAGGTGCTGTTCTTCACGAACCAGCCCGATCTGAGCG
TCGAGACCCAGATCGCATTCGGCAAGCTGTTCGGCGAGCTGGAGACGAATTTTCCATCGTTTACCGCGAAGCCCGACGGG
CAACCCGAGGTCACGGTGTTCGACGGCGCGGTGTCGACCGGCCGCGCGTCGATCTGGCACACGGACCTGAGCATCGCGAA
GACGCCGAGCGCGATGGGCATCCTGTGCGTGAAGGAGACTCCGGCGAGCGGCGGCGACACGATGTGGGCCGACCTCGAGG
CCGCATACGCGGCGCTGTCGCCGGGCATGCAGGCGTTTCTCGAAGGGCAGCGCGCGGTGCACGACATGATGACCCCGCAG
TACGCGCAGCGCCCGGGCGCGTTCCAGACGCAGGGCCGCTCGGACATGGATCTGTCCGAAGTGTTCGGCGCCGAGCATCC
GGTGGTGCGCGTGCATCCGGAGACGGGGCGCAAGTGCCTGTTCGTCAATCCGTTCCTCACGTCCCACATCACGGGCTTTC
ACTCGGCCGAGAGCGCGACGATCCTCAACTACCTGTATGCGTTGATGGAGCGGCCGCAGTACGTGGTGCGCTGGCACTGG
TCGAACGGCGACGTCGCGCTGTGGGACAACCGGTGCACGATGCACACGGCCGTCGACGACTACGGCGCGGGCCGCCGCTT
CGCGCGGCGCGTGTGCGTGCGCGGGGACGTGCCGTACGGCGTCGGCGAACGCACGCCGGCTGCGGCCGCCGCCGCATGA

Upstream 100 bases:

>100_bases
CATTTCGAGTCTGTCGCCGCGAGCGGCGGCGGCCGGGATGCGGATCGTTCGGCCGATCGCACGGCCGACCACGCGGTTCA
TACGACAAGGAGCTGACGAG

Downstream 100 bases:

>100_bases
CGGGCGGCGGCAGACACGATCGCCGCGGGCAGTCCGCGGCAGACCATTCAATTTAGCGCGAGTCCGATATGTCAAATCAG
TTGATTCAATCAGGCGTCGA

Product: dioxygenase, TauD/TfdA

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
METLEIRPLSGTIGAQVRNRTLAGVVESGRVDEIRQALLRYKVLFFTNQPDLSVETQIAFGKLFGELETNFPSFTAKPDG
QPEVTVFDGAVSTGRASIWHTDLSIAKTPSAMGILCVKETPASGGDTMWADLEAAYAALSPGMQAFLEGQRAVHDMMTPQ
YAQRPGAFQTQGRSDMDLSEVFGAEHPVVRVHPETGRKCLFVNPFLTSHITGFHSAESATILNYLYALMERPQYVVRWHW
SNGDVALWDNRCTMHTAVDDYGAGRRFARRVCVRGDVPYGVGERTPAAAAAA

Sequences:

>Translated_292_residues
METLEIRPLSGTIGAQVRNRTLAGVVESGRVDEIRQALLRYKVLFFTNQPDLSVETQIAFGKLFGELETNFPSFTAKPDG
QPEVTVFDGAVSTGRASIWHTDLSIAKTPSAMGILCVKETPASGGDTMWADLEAAYAALSPGMQAFLEGQRAVHDMMTPQ
YAQRPGAFQTQGRSDMDLSEVFGAEHPVVRVHPETGRKCLFVNPFLTSHITGFHSAESATILNYLYALMERPQYVVRWHW
SNGDVALWDNRCTMHTAVDDYGAGRRFARRVCVRGDVPYGVGERTPAAAAAA
>Mature_292_residues
METLEIRPLSGTIGAQVRNRTLAGVVESGRVDEIRQALLRYKVLFFTNQPDLSVETQIAFGKLFGELETNFPSFTAKPDG
QPEVTVFDGAVSTGRASIWHTDLSIAKTPSAMGILCVKETPASGGDTMWADLEAAYAALSPGMQAFLEGQRAVHDMMTPQ
YAQRPGAFQTQGRSDMDLSEVFGAEHPVVRVHPETGRKCLFVNPFLTSHITGFHSAESATILNYLYALMERPQYVVRWHW
SNGDVALWDNRCTMHTAVDDYGAGRRFARRVCVRGDVPYGVGERTPAAAAAA

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=281, Percent_Identity=36.2989323843416, Blast_Score=174, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6322971, Length=291, Percent_Identity=29.2096219931272, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 32030; Mature: 32030

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLEIRPLSGTIGAQVRNRTLAGVVESGRVDEIRQALLRYKVLFFTNQPDLSVETQIAF
CCCEEEEECCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCCEEHHHHH
GKLFGELETNFPSFTAKPDGQPEVTVFDGAVSTGRASIWHTDLSIAKTPSAMGILCVKET
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECC
PASGGDTMWADLEAAYAALSPGMQAFLEGQRAVHDMMTPQYAQRPGAFQTQGRSDMDLSE
CCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHH
VFGAEHPVVRVHPETGRKCLFVNPFLTSHITGFHSAESATILNYLYALMERPQYVVRWHW
HCCCCCCEEEECCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
SNGDVALWDNRCTMHTAVDDYGAGRRFARRVCVRGDVPYGVGERTPAAAAAA
CCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
METLEIRPLSGTIGAQVRNRTLAGVVESGRVDEIRQALLRYKVLFFTNQPDLSVETQIAF
CCCEEEEECCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCCEEHHHHH
GKLFGELETNFPSFTAKPDGQPEVTVFDGAVSTGRASIWHTDLSIAKTPSAMGILCVKET
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECC
PASGGDTMWADLEAAYAALSPGMQAFLEGQRAVHDMMTPQYAQRPGAFQTQGRSDMDLSE
CCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHH
VFGAEHPVVRVHPETGRKCLFVNPFLTSHITGFHSAESATILNYLYALMERPQYVVRWHW
HCCCCCCEEEECCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
SNGDVALWDNRCTMHTAVDDYGAGRRFARRVCVRGDVPYGVGERTPAAAAAA
CCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]