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The map label for this gene is hisE [H]

Identifier: 161723153

GI number: 161723153

Start: 3426853

End: 3427221

Strand: Reverse

Name: hisE [H]

Synonym: BTH_I2985

Alternate gene names: 161723153

Gene position: 3427221-3426853 (Counterclockwise)

Preceding gene: 83719448

Following gene: 83720897

Centisome position: 89.97

GC content: 67.48

Gene sequence:

>369_bases
ATGACGCAACCGACGATCGAAGACACGCTGCTGCGCTTGGCGGCCGTGATCGACAGCCGCAAGGGCGGCGATCCTGAGCA
ATCGTACGTGTCGCGCCTCTTTCACAAGGGCGACGACGCGGTTCTGAAGAAGATCGGCGAGGAAGCGACGGAAGTCGTGC
TCGCCGCGAAGGACGTGCGCCAGGGCGGCGCGCCGTCCGCGCTCGTCGGCGAGGTCGCGGACCTGTGGTTCCATTGCCTC
GTCGCGCTGTCGCATTTCGACCTGAGCCCCGCCGACGTGATCGCCGAGCTCGAGCGCCGCGAAGGGATGTCGGGCATCGA
GGAAAAGGCGCTGCGCAAGCGCCGCGAGCGCGAGGAAAACGGCGGGTGA

Upstream 100 bases:

>100_bases
GCCGGCGCTCGTGCTTTTTCCAGAAATTCGAGGGCACCGTCGACGACGGCGAATGGGTCGCGGTCGATCCGGTGCTCAAA
GATCCCGAACATATCTACAA

Downstream 100 bases:

>100_bases
GCCGATGCGGCCACACGCCGCGCAAGTTTTGTCATCAAAGGGGAATAGCATCATGCCGGAGTCGCCGAACCAATTTCCAC
CGTCGTACCAGAGCGCGACC

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTQPTIEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCL
VALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG

Sequences:

>Translated_122_residues
MTQPTIEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCL
VALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG
>Mature_121_residues
TQPTIEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLV
ALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 13369; Mature: 13238

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPTIEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVR
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREEN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GG
CC
>Mature Secondary Structure 
TQPTIEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVR
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREEN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA