Click here to switch to the map view.

The map label for this gene is dinB [H]

Identifier: 161723133

GI number: 161723133

Start: 2097815

End: 2098993

Strand: Direct

Name: dinB [H]

Synonym: BTH_I1859

Alternate gene names: 161723133

Gene position: 2097815-2098993 (Clockwise)

Preceding gene: 83721563

Following gene: 83718787

Centisome position: 55.07

GC content: 69.3

Gene sequence:

>1179_bases
GTGAACAAGCCGACGCCTTCCCCCGACCCGTATTCGCCGCCTTTGGGCGACGCGGCCCCGTTCGCGCGCAAGATTATCCA
TTGCGACTGCGATTGCTTCTACGCGTCGGTCGAGATGCGCGACGATCCGTCGCTGCGCGGCCGCCCGCTCGCGGTCGGCG
GCCGCCCCGATCAGCGCGGCGTGATCGCGACCTGCAACTACGAGGCGCGGCGCTTCGGCGTGCATTCGGCGATGTCGTCG
GCGCTCGCGATGCGCAAGTGTCCGGACCTCCTGATCCTGCCCTCCGCGATGGACAAGTATCGCGCGGCGTCGCGGCTCAT
CATGGCGATCTATCGCGACTACACGCCCGACGTCGAGCCGCTGTCGCTCGACGAGGCGTATCTCGACGTGAGCCGCGCGA
CGCGCTGTCACGGCAGCGGCACGCTGATCGCGCGCGAGATCCGCGAGCGCGTGCGCGACACGGTGGGCGTCACGGTGTCG
GCGGGCGTCGCGCCGAACAAGTTCATCGCGAAGATCGCGTCCGACTGGAACAAGCCCGATGGCCTGTTCGTCGTGCGGCC
GCACGAAGTCGACGCGTTCGTCGCCGCGCTGCCCGTGCGCAAGCTGCACGGCGTCGGCAAGGTGACGGCGGCGCGGCTCG
ACAAGCTCGGCATTCGCACCTGCAGCGAGCTGCGCGGCTGGTCGCTGTTCGATCTGCATCACGAGTTCGGCGCGTTCGGC
CGGCGGCTCTACGAGCTTGCGCGCGGCATCGACGAGCGGCCGGTGCGCGCGGACCAGGAGCGCAAGTCGGTGAGCGTCGA
GACGACCTATGTGCAGGATCTCGCCACGCTCGACCAATGCGCGGCGGAGATCCGTCGACTGACGGCGCTGCTCGATGCGC
GGATCGAGCGGGCCGGGGCCGCGCGCTCGATCAGGAAGCTCTACGTGAAGATCCGTTTCGCGGATTTTCAGCGCACGACG
GTCGAGTGCGTCGCCGACGCGACCGATGCCGAAACCGCGGTCTCGCTGCTCGCGAAAGGGCTCGCGCGCCGCAAGCAGGC
GGTGCGGCTGTTGGGCGTCGGCGTGCGGATCGACGAGGACACGGCCGAGCGGCACGGACAGATCGCGCTCTTCGACGACG
AGGTCATGAACGGCGACGGTGACGATGGCGGCGAAGGCGATGCGTCGTCCGACGCGTGA

Upstream 100 bases:

>100_bases
TCGCCCCGCCGACGCAGCCCGGGCTCCTCGGGAGTCGCGCCACGCGAAGCCGCGCCGCGCAGTTGAAACGCTCACTGTGT
TTTTGTACAGTATCGGCACC

Downstream 100 bases:

>100_bases
TCGAACGCGCGAGGGCTCGGTGCCTGCCTGGCGCCTCGGTGCGGCGCGATAAAAAAACGGCAACCCGTCGGTACGGGTTG
CCATTCGTCGCCTTTCGCGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNKPTPSPDPYSPPLGDAAPFARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYEARRFGVHSAMSS
ALAMRKCPDLLILPSAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCHGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCSELRGWSLFDLHHEFGAFG
RRLYELARGIDERPVRADQERKSVSVETTYVQDLATLDQCAAEIRRLTALLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDAETAVSLLAKGLARRKQAVRLLGVGVRIDEDTAERHGQIALFDDEVMNGDGDDGGEGDASSDA

Sequences:

>Translated_392_residues
MNKPTPSPDPYSPPLGDAAPFARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYEARRFGVHSAMSS
ALAMRKCPDLLILPSAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCHGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCSELRGWSLFDLHHEFGAFG
RRLYELARGIDERPVRADQERKSVSVETTYVQDLATLDQCAAEIRRLTALLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDAETAVSLLAKGLARRKQAVRLLGVGVRIDEDTAERHGQIALFDDEVMNGDGDDGGEGDASSDA
>Mature_392_residues
MNKPTPSPDPYSPPLGDAAPFARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYEARRFGVHSAMSS
ALAMRKCPDLLILPSAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCHGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCSELRGWSLFDLHHEFGAFG
RRLYELARGIDERPVRADQERKSVSVETTYVQDLATLDQCAAEIRRLTALLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDAETAVSLLAKGLARRKQAVRLLGVGVRIDEDTAERHGQIALFDDEVMNGDGDDGGEGDASSDA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=29.6187683284457, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=29.5321637426901, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI154350220, Length=317, Percent_Identity=29.6529968454259, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI7705344, Length=124, Percent_Identity=44.3548387096774, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI5729982, Length=156, Percent_Identity=33.974358974359, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1786425, Length=350, Percent_Identity=47.4285714285714, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI1787432, Length=206, Percent_Identity=30.5825242718447, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=425, Percent_Identity=29.1764705882353, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=257, Percent_Identity=31.5175097276265, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=368, Percent_Identity=25.8152173913043, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=127, Percent_Identity=40.1574803149606, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=28.1553398058252, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19923006, Length=346, Percent_Identity=26.878612716763, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355641, Length=295, Percent_Identity=29.8305084745763, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24644984, Length=295, Percent_Identity=29.8305084745763, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43056; Mature: 43056

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPTPSPDPYSPPLGDAAPFARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRG
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCC
VIATCNYEARRFGVHSAMSSALAMRKCPDLLILPSAMDKYRAASRLIMAIYRDYTPDVEP
EEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
LSLDEAYLDVSRATRCHGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCC
GLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCSELRGWSLFDLHHEFGAFG
CEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
RRLYELARGIDERPVRADQERKSVSVETTYVQDLATLDQCAAEIRRLTALLDARIERAGA
HHHHHHHCCCCCCCCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIRKLYVKIRFADFQRTTVECVADATDAETAVSLLAKGLARRKQAVRLLGVGVRIDED
HHHHHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
TAERHGQIALFDDEVMNGDGDDGGEGDASSDA
HHHHCCCEEEECHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKPTPSPDPYSPPLGDAAPFARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRG
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCC
VIATCNYEARRFGVHSAMSSALAMRKCPDLLILPSAMDKYRAASRLIMAIYRDYTPDVEP
EEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
LSLDEAYLDVSRATRCHGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCC
GLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCSELRGWSLFDLHHEFGAFG
CEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
RRLYELARGIDERPVRADQERKSVSVETTYVQDLATLDQCAAEIRRLTALLDARIERAGA
HHHHHHHCCCCCCCCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIRKLYVKIRFADFQRTTVECVADATDAETAVSLLAKGLARRKQAVRLLGVGVRIDED
HHHHHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
TAERHGQIALFDDEVMNGDGDDGGEGDASSDA
HHHHCCCEEEECHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]