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The map label for this gene is gidA

Identifier: 83591334

GI number: 83591334

Start: 2623499

End: 2625391

Strand: Reverse

Name: gidA

Synonym: Moth_2518

Alternate gene names: 83591334

Gene position: 2625391-2623499 (Counterclockwise)

Preceding gene: 83591335

Following gene: 83591333

Centisome position: 99.87

GC content: 56.52

Gene sequence:

>1893_bases
ATGTACAACGCCGGTAATTATGATGTTATTGTTATCGGCGCCGGTCACGCTGGTTGCGAAGCAGCCCTGGCGGCGGCCAA
ACTGGGATGCCGGACCCTGATGCTGACCATTAGCCTGGAGAGTATCGCCATGATGCCCTGCAACCCCTCAATTGGCGGTC
CCGCCAAGGGCCACCTGGTAAGGGAGATCGATGCCCTTGGCGGTATCATGGGCCTTAATATCGACCGGAGTCGTATCCAG
ATCCGCCGCCTCAATAGCGGTAAAGGACCGGCGGTGAGGGCCCTGCGGGCCCAGGCCGATAAAAAACTCTACCAGCGGGA
AATGACCCTGACCCTGGAGCGCCAGGAACATCTAGATGTTAAACAGGCGGAAGTTATCCGCATCCTGACAGAAAGCGGAC
GAGTGAAGGGTGTCTTGACCAGGACAGGGGCCTATTTTGCCTGCCGGGCCATAGTTTTGACTACCGGGACTTATCTCCGC
GGCCGGATTATCATTGGCGAGGTAGCCTATGCTGGCGGGCCCAATGGCCAGTTCCCGGCCATCGAGCTGGCGGCCAGCTT
GAAGGAACTTGGCCTGCGTATGGGACGTTTCAAGACAGGCACGCCGCCCCGGGTGAGCGGTCGTTCCATTAACTGGGATA
AAATGACGGAGCAGCCAGGGGACCCTGGCCCCTTGCGGTTTTCTTTCTGGGAAGAGGGACCGGAGCGACCAAATGTATCC
TGCTGGCTCACCCATACCAATACTACGACCCATAATATTATCAAGGACAATCTCCACCGGGCACCTTTATTCAGCGGTTT
AATAGAGGGTAAAGGGCCGAGATACTGTCCTTCCATCGAGGACAAGGTAGTGCGCTTTGCCGATAAACCCGGCCACCAGA
TTTTCCTGGAGCCGGAAGGCATGGGGACAGAAGAATGGTATGTCCAGGGTCTGTCGACCAGCTTGCCGGAGGATGTGCAG
CTGGCAGTGCTCCACAGTGTGCCGGGATTGGAGCAGGCCGAGATGATGCGGCCGGGCTATGCTATTGAGTATGACTATAT
TGATCCTACCCAGCTCAAGGCCTCCCTTGAGTGTAAGCACATCGCCGGTCTCTTTACAGCCGGCCAGATTAACGGCACCT
CCGGATATGAGGAGGCGGCGGCCCAGGGGCTGGTGGCCGGCATCAATGCCGCCCGCCTGGTGCGGGAGCAGGAGCCCCTG
ATTTTAAGGCGTGACCAGGCCTATATTGGCGTCCTTATTGACGACCTGGTTACCAGGGGTGTAACCGAGCCGTACCGCCT
GTTGACTTCCCGTGCCGAACACCGTTTGCTCCTGCGGGAGGATAATGCCGACCTGCGCCTGGGTAGAATCGGTTATGAGA
TCGGTTTGCTGGATGAGCAGCGTTTCCGAAAGCTGGAAGCCAAGGAAAAAGCCATAAATGACGGCCTTGTTTACCTTGGT
AAGCAACATGTAGGCGGTAATAACCCAAAAATACAGGAAATAATAGTCGCCTGCGGTGAACCCCCCCTGAAGGGTACCAC
GAGTTTAAAGGATCTCATGCGGCGGCCCCGGATAAAGTATCAAGATCTGGCTGCCGCCGGCCTGGTACCTGAACTGCCAC
CGGAAATTGCCGCGGAGATAGAAATGATGGTCAAGTACGAGGGTTATATCGCTAAAGAGAAGATCCAGGTTGAAAGGTTG
GCCAAACTTGAAGCCCGGGTGTTGCCGGCGGATCTGAATTATAGTGAAATTCGCGGTCTTTCCAGGGAAAGTATCGACCA
CCTGGAAAGGGTAAAGCCGCGTTCCCTGGGGCAGGCCCTGCGCATCCCCGGGGTTACCCCAGCTGACATCAGTGTCCTTT
TAGTTTACCTGGAGCAGAAGAAGCGGGAAGGGGCCAAAGCCTGTGCGGGATAG

Upstream 100 bases:

>100_bases
TCGGAACCACTGCCCGGGAGGATCTTCTGGACCGGATATTCAGCGATTTCTGCATCGGCAAGTAAACAAGTAAAATAAAA
AAGAAAGGATGGTGAAAGGG

Downstream 100 bases:

>100_bases
GGATCGCCTCCTGGCAGCTTTCAGCAAGGATACCGGTATAACCTTGAAACCGGAGCAGATCGCCATGATAGAGGCTTATA
CCGGGTTGCTGCTGGACTAT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MYNAGNYDVIVIGAGHAGCEAALAAAKLGCRTLMLTISLESIAMMPCNPSIGGPAKGHLVREIDALGGIMGLNIDRSRIQ
IRRLNSGKGPAVRALRAQADKKLYQREMTLTLERQEHLDVKQAEVIRILTESGRVKGVLTRTGAYFACRAIVLTTGTYLR
GRIIIGEVAYAGGPNGQFPAIELAASLKELGLRMGRFKTGTPPRVSGRSINWDKMTEQPGDPGPLRFSFWEEGPERPNVS
CWLTHTNTTTHNIIKDNLHRAPLFSGLIEGKGPRYCPSIEDKVVRFADKPGHQIFLEPEGMGTEEWYVQGLSTSLPEDVQ
LAVLHSVPGLEQAEMMRPGYAIEYDYIDPTQLKASLECKHIAGLFTAGQINGTSGYEEAAAQGLVAGINAARLVREQEPL
ILRRDQAYIGVLIDDLVTRGVTEPYRLLTSRAEHRLLLREDNADLRLGRIGYEIGLLDEQRFRKLEAKEKAINDGLVYLG
KQHVGGNNPKIQEIIVACGEPPLKGTTSLKDLMRRPRIKYQDLAAAGLVPELPPEIAAEIEMMVKYEGYIAKEKIQVERL
AKLEARVLPADLNYSEIRGLSRESIDHLERVKPRSLGQALRIPGVTPADISVLLVYLEQKKREGAKACAG

Sequences:

>Translated_630_residues
MYNAGNYDVIVIGAGHAGCEAALAAAKLGCRTLMLTISLESIAMMPCNPSIGGPAKGHLVREIDALGGIMGLNIDRSRIQ
IRRLNSGKGPAVRALRAQADKKLYQREMTLTLERQEHLDVKQAEVIRILTESGRVKGVLTRTGAYFACRAIVLTTGTYLR
GRIIIGEVAYAGGPNGQFPAIELAASLKELGLRMGRFKTGTPPRVSGRSINWDKMTEQPGDPGPLRFSFWEEGPERPNVS
CWLTHTNTTTHNIIKDNLHRAPLFSGLIEGKGPRYCPSIEDKVVRFADKPGHQIFLEPEGMGTEEWYVQGLSTSLPEDVQ
LAVLHSVPGLEQAEMMRPGYAIEYDYIDPTQLKASLECKHIAGLFTAGQINGTSGYEEAAAQGLVAGINAARLVREQEPL
ILRRDQAYIGVLIDDLVTRGVTEPYRLLTSRAEHRLLLREDNADLRLGRIGYEIGLLDEQRFRKLEAKEKAINDGLVYLG
KQHVGGNNPKIQEIIVACGEPPLKGTTSLKDLMRRPRIKYQDLAAAGLVPELPPEIAAEIEMMVKYEGYIAKEKIQVERL
AKLEARVLPADLNYSEIRGLSRESIDHLERVKPRSLGQALRIPGVTPADISVLLVYLEQKKREGAKACAG
>Mature_630_residues
MYNAGNYDVIVIGAGHAGCEAALAAAKLGCRTLMLTISLESIAMMPCNPSIGGPAKGHLVREIDALGGIMGLNIDRSRIQ
IRRLNSGKGPAVRALRAQADKKLYQREMTLTLERQEHLDVKQAEVIRILTESGRVKGVLTRTGAYFACRAIVLTTGTYLR
GRIIIGEVAYAGGPNGQFPAIELAASLKELGLRMGRFKTGTPPRVSGRSINWDKMTEQPGDPGPLRFSFWEEGPERPNVS
CWLTHTNTTTHNIIKDNLHRAPLFSGLIEGKGPRYCPSIEDKVVRFADKPGHQIFLEPEGMGTEEWYVQGLSTSLPEDVQ
LAVLHSVPGLEQAEMMRPGYAIEYDYIDPTQLKASLECKHIAGLFTAGQINGTSGYEEAAAQGLVAGINAARLVREQEPL
ILRRDQAYIGVLIDDLVTRGVTEPYRLLTSRAEHRLLLREDNADLRLGRIGYEIGLLDEQRFRKLEAKEKAINDGLVYLG
KQHVGGNNPKIQEIIVACGEPPLKGTTSLKDLMRRPRIKYQDLAAAGLVPELPPEIAAEIEMMVKYEGYIAKEKIQVERL
AKLEARVLPADLNYSEIRGLSRESIDHLERVKPRSLGQALRIPGVTPADISVLLVYLEQKKREGAKACAG

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=645, Percent_Identity=42.4806201550388, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI19882217, Length=670, Percent_Identity=40.8955223880597, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI183227703, Length=685, Percent_Identity=40, Blast_Score=417, Evalue=1e-116,
Organism=Escherichia coli, GI2367273, Length=624, Percent_Identity=51.6025641025641, Blast_Score=609, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI17534255, Length=624, Percent_Identity=38.1410256410256, Blast_Score=422, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321202, Length=622, Percent_Identity=41.8006430868167, Blast_Score=450, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24658174, Length=644, Percent_Identity=40.9937888198758, Blast_Score=429, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_MOOTA (Q2RFI9)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431343.1
- HSSP:   Q5SH33
- ProteinModelPortal:   Q2RFI9
- SMR:   Q2RFI9
- STRING:   Q2RFI9
- GeneID:   3832573
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2518
- NMPDR:   fig|264732.9.peg.2550
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   MTHE264732:MOTH_2518-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 69354; Mature: 69354

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNAGNYDVIVIGAGHAGCEAALAAAKLGCRTLMLTISLESIAMMPCNPSIGGPAKGHLV
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEECCEEEECCCCCCCCCCCCHHH
REIDALGGIMGLNIDRSRIQIRRLNSGKGPAVRALRAQADKKLYQREMTLTLERQEHLDV
HHHHHHCCEEECCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCH
KQAEVIRILTESGRVKGVLTRTGAYFACRAIVLTTGTYLRGRIIIGEVAYAGGPNGQFPA
HHHHHHHHHHCCCCEEEEEEECCHHHHHEEHEEECCCEEEEEEEEEEEEECCCCCCCCCH
IELAASLKELGLRMGRFKTGTPPRVSGRSINWDKMTEQPGDPGPLRFSFWEEGPERPNVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCE
CWLTHTNTTTHNIIKDNLHRAPLFSGLIEGKGPRYCPSIEDKVVRFADKPGHQIFLEPEG
EEEEECCCCHHHHHHHCCHHCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCC
MGTEEWYVQGLSTSLPEDVQLAVLHSVPGLEQAEMMRPGYAIEYDYIDPTQLKASLECKH
CCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEEECCCCHHHHHHHCCHHH
IAGLFTAGQINGTSGYEEAAAQGLVAGINAARLVREQEPLILRRDQAYIGVLIDDLVTRG
HHHEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHC
VTEPYRLLTSRAEHRLLLREDNADLRLGRIGYEIGLLDEQRFRKLEAKEKAINDGLVYLG
CCHHHHHHHHHHHCEEEEEECCCCEEEEEECEEEECCCHHHHHHHHHHHHHHCCCEEEEE
KQHVGGNNPKIQEIIVACGEPPLKGTTSLKDLMRRPRIKYQDLAAAGLVPELPPEIAAEI
HHHCCCCCCCHHHHHEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
EMMVKYEGYIAKEKIQVERLAKLEARVLPADLNYSEIRGLSRESIDHLERVKPRSLGQAL
HHEEEECCEEEHHHHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHHCCCHHHCCEE
RIPGVTPADISVLLVYLEQKKREGAKACAG
ECCCCCCCCHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MYNAGNYDVIVIGAGHAGCEAALAAAKLGCRTLMLTISLESIAMMPCNPSIGGPAKGHLV
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEECCEEEECCCCCCCCCCCCHHH
REIDALGGIMGLNIDRSRIQIRRLNSGKGPAVRALRAQADKKLYQREMTLTLERQEHLDV
HHHHHHCCEEECCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCH
KQAEVIRILTESGRVKGVLTRTGAYFACRAIVLTTGTYLRGRIIIGEVAYAGGPNGQFPA
HHHHHHHHHHCCCCEEEEEEECCHHHHHEEHEEECCCEEEEEEEEEEEEECCCCCCCCCH
IELAASLKELGLRMGRFKTGTPPRVSGRSINWDKMTEQPGDPGPLRFSFWEEGPERPNVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCE
CWLTHTNTTTHNIIKDNLHRAPLFSGLIEGKGPRYCPSIEDKVVRFADKPGHQIFLEPEG
EEEEECCCCHHHHHHHCCHHCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCC
MGTEEWYVQGLSTSLPEDVQLAVLHSVPGLEQAEMMRPGYAIEYDYIDPTQLKASLECKH
CCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEEECCCCHHHHHHHCCHHH
IAGLFTAGQINGTSGYEEAAAQGLVAGINAARLVREQEPLILRRDQAYIGVLIDDLVTRG
HHHEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHC
VTEPYRLLTSRAEHRLLLREDNADLRLGRIGYEIGLLDEQRFRKLEAKEKAINDGLVYLG
CCHHHHHHHHHHHCEEEEEECCCCEEEEEECEEEECCCHHHHHHHHHHHHHHCCCEEEEE
KQHVGGNNPKIQEIIVACGEPPLKGTTSLKDLMRRPRIKYQDLAAAGLVPELPPEIAAEI
HHHCCCCCCCHHHHHEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
EMMVKYEGYIAKEKIQVERLAKLEARVLPADLNYSEIRGLSRESIDHLERVKPRSLGQAL
HHEEEECCEEEHHHHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHHCCCHHHCCEE
RIPGVTPADISVLLVYLEQKKREGAKACAG
ECCCCCCCCHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA