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The map label for this gene is atsB [H]

Identifier: 83591239

GI number: 83591239

Start: 2545855

End: 2547276

Strand: Reverse

Name: atsB [H]

Synonym: Moth_2423

Alternate gene names: 83591239

Gene position: 2547276-2545855 (Counterclockwise)

Preceding gene: 83591240

Following gene: 83591238

Centisome position: 96.9

GC content: 59.56

Gene sequence:

>1422_bases
TTGACCGCAACCTTAAACCTGCAAATGGTCGACTGGCAGGGTGACCTGCACTGGTTCGACTTTGAAGACCTGACCCTACT
CCTGGATGTCAACAGCGGTGCCGTACACCTCATTGACGCCGCGGCCCGGGATGTCCTGGAGGAGTTAAGGGACCGTCAGG
AACAGGGCGTACTGACGGCGGAGGACTTGATCACCGTCCTGCCCCGGGCCGTCCGGACCTGGGGAACGGCTACCGTCCTG
GAGGTATGCCGGGAACTGGCAGCCAGACAGGCCGCCGGTACCCTTTTTAGCGTCGATGAAGTCGGCAGGAATTACCGGCC
GCCGCAGCCTTCCCTCCAGGCCCTCTGCCTGCATGTTGCCCACGATTGTAACATGCGCTGCCGTTACTGCTTTGCCGACG
GAGGTCCCTTCGGTGGCGAGCGCGGTCTCATGAACCGGGATACCGGTTATGCGGCCCTCGATCTCCTCTTCCGGGAAGCA
GGCAACCGCCCGCGGGTAGAGGTAGACTTTTTCGGTGGGGAACCCCTTTTGAACTTCGGTGTGGTCCGGGAACTGGTGGC
TTACGGCCGGGAAAAGGCAGCCGCAGCCGGTAAGGGAATCAGCTTCACTCTGACAACCAATGGCCTGGCCTTAAGCCCGG
AAATTGAAAACTACTTGATCACTGAGGGCGTGAGCGTCATCCTGAGCCTGGATGGTCGCCGGGAGGTCCATGATTTCAAC
CGGCCTGACGCCGCCGGCCGGGGCACTTATGAACGAGTTGTCCCCAGGGAGCAGCATTTTGTCGCTAGCCAGGGGCACCG
GGACTACTGGGTCCGGGGAACCTACACTCGCCAGAATCTTGATTTTACCAGTGATATCCTGCATATGGTAGAGTTAGGGT
TTCGTTACCTGTCCATGGAGCCGGTGGTAGCGGCCCCTGAGGCCGAATATGCTATTAAAGAGGAAGATTTACCCCGGCTG
GCAGGGGAGTACCGGCGCCTGGCCCGGATTTACCTGGAGAGGGCGAGGGCAGGAAAAGGTTTTTCCTTTTTTCATTTCAA
TATCGATGCCGCTGCCGGGCCGTGCCTGACAAAAAGACTTACCGGTTGTGGTGCCGGTACCAGTTACCTGGCTGTAACCC
CGGCAGGGGACCTCTATCCCTGTCACCAGCTCGTCGGGCGTAAGGATTACTGCCTGGGTAATGTCCGGGAGGGAATCCGG
CGTCCCGAGCTGCGGGAAGCCTTCCGCCAGGCTTATGTCTATAACCAGCCGGCCTGCAGTCGTTGCTGGGCACGCTTTTA
TTGCAGTGGCGGCTGCCACGCGGCCAACCTGGCTGCTACCGGCGACCTGCGCCAGCCGGCACCAATCGCTTGCGCCATCC
AAAAAATGCGCCTGGAAGCCGCCCTTTACGTTCAGGTAAAAATGGCGGGAAAATTTTGTTGA

Upstream 100 bases:

>100_bases
CCGTGAGCAACCAGCCCTGCGAACGTAAAGTCAGGAACTAACCTCCGGGCCCGACACCACCTGTCGGGCCTTTGTTGTAT
ATGTGGAAAGGAAGAGAAAA

Downstream 100 bases:

>100_bases
GGGGGCAGGATTCCTGGCAAGTGAGGTAGAATATTTTTATTTACGGGTTATTTTTTTGGAGACGAGGAGGAATGCCATGC
CGCCGCCAGATAAGCTACCG

Product: radical SAM family protein

Products: NA

Alternate protein names: AnSME; Arylsulfatase-activating protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTATLNLQMVDWQGDLHWFDFEDLTLLLDVNSGAVHLIDAAARDVLEELRDRQEQGVLTAEDLITVLPRAVRTWGTATVL
EVCRELAARQAAGTLFSVDEVGRNYRPPQPSLQALCLHVAHDCNMRCRYCFADGGPFGGERGLMNRDTGYAALDLLFREA
GNRPRVEVDFFGGEPLLNFGVVRELVAYGREKAAAAGKGISFTLTTNGLALSPEIENYLITEGVSVILSLDGRREVHDFN
RPDAAGRGTYERVVPREQHFVASQGHRDYWVRGTYTRQNLDFTSDILHMVELGFRYLSMEPVVAAPEAEYAIKEEDLPRL
AGEYRRLARIYLERARAGKGFSFFHFNIDAAAGPCLTKRLTGCGAGTSYLAVTPAGDLYPCHQLVGRKDYCLGNVREGIR
RPELREAFRQAYVYNQPACSRCWARFYCSGGCHAANLAATGDLRQPAPIACAIQKMRLEAALYVQVKMAGKFC

Sequences:

>Translated_473_residues
MTATLNLQMVDWQGDLHWFDFEDLTLLLDVNSGAVHLIDAAARDVLEELRDRQEQGVLTAEDLITVLPRAVRTWGTATVL
EVCRELAARQAAGTLFSVDEVGRNYRPPQPSLQALCLHVAHDCNMRCRYCFADGGPFGGERGLMNRDTGYAALDLLFREA
GNRPRVEVDFFGGEPLLNFGVVRELVAYGREKAAAAGKGISFTLTTNGLALSPEIENYLITEGVSVILSLDGRREVHDFN
RPDAAGRGTYERVVPREQHFVASQGHRDYWVRGTYTRQNLDFTSDILHMVELGFRYLSMEPVVAAPEAEYAIKEEDLPRL
AGEYRRLARIYLERARAGKGFSFFHFNIDAAAGPCLTKRLTGCGAGTSYLAVTPAGDLYPCHQLVGRKDYCLGNVREGIR
RPELREAFRQAYVYNQPACSRCWARFYCSGGCHAANLAATGDLRQPAPIACAIQKMRLEAALYVQVKMAGKFC
>Mature_472_residues
TATLNLQMVDWQGDLHWFDFEDLTLLLDVNSGAVHLIDAAARDVLEELRDRQEQGVLTAEDLITVLPRAVRTWGTATVLE
VCRELAARQAAGTLFSVDEVGRNYRPPQPSLQALCLHVAHDCNMRCRYCFADGGPFGGERGLMNRDTGYAALDLLFREAG
NRPRVEVDFFGGEPLLNFGVVRELVAYGREKAAAAGKGISFTLTTNGLALSPEIENYLITEGVSVILSLDGRREVHDFNR
PDAAGRGTYERVVPREQHFVASQGHRDYWVRGTYTRQNLDFTSDILHMVELGFRYLSMEPVVAAPEAEYAIKEEDLPRLA
GEYRRLARIYLERARAGKGFSFFHFNIDAAAGPCLTKRLTGCGAGTSYLAVTPAGDLYPCHQLVGRKDYCLGNVREGIRR
PELREAFRQAYVYNQPACSRCWARFYCSGGCHAANLAATGDLRQPAPIACAIQKMRLEAALYVQVKMAGKFC

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of serine ('Ser-72' in the arylsulfatase AtsA) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemica

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 52619; Mature: 52488

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLNLQMVDWQGDLHWFDFEDLTLLLDVNSGAVHLIDAAARDVLEELRDRQEQGVLTA
CCEEEEEEEEEECCCEEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCH
EDLITVLPRAVRTWGTATVLEVCRELAARQAAGTLFSVDEVGRNYRPPQPSLQALCLHVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCHHHHHHHHHHH
HDCNMRCRYCFADGGPFGGERGLMNRDTGYAALDLLFREAGNRPRVEVDFFGGEPLLNFG
HCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
VVRELVAYGREKAAAAGKGISFTLTTNGLALSPEIENYLITEGVSVILSLDGRREVHDFN
HHHHHHHHCCHHHHHCCCCEEEEEECCCEEECCCHHHHHHHCCEEEEEEECCCHHHHCCC
RPDAAGRGTYERVVPREQHFVASQGHRDYWVRGTYTRQNLDFTSDILHMVELGFRYLSME
CCCCCCCCCHHHCCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
PVVAAPEAEYAIKEEDLPRLAGEYRRLARIYLERARAGKGFSFFHFNIDAAAGPCLTKRL
CEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHH
TGCGAGTSYLAVTPAGDLYPCHQLVGRKDYCLGNVREGIRRPELREAFRQAYVYNQPACS
HCCCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
RCWARFYCSGGCHAANLAATGDLRQPAPIACAIQKMRLEAALYVQVKMAGKFC
HHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHEEEEEEEEEECCCCC
>Mature Secondary Structure 
TATLNLQMVDWQGDLHWFDFEDLTLLLDVNSGAVHLIDAAARDVLEELRDRQEQGVLTA
CEEEEEEEEEECCCEEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCH
EDLITVLPRAVRTWGTATVLEVCRELAARQAAGTLFSVDEVGRNYRPPQPSLQALCLHVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCHHHHHHHHHHH
HDCNMRCRYCFADGGPFGGERGLMNRDTGYAALDLLFREAGNRPRVEVDFFGGEPLLNFG
HCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
VVRELVAYGREKAAAAGKGISFTLTTNGLALSPEIENYLITEGVSVILSLDGRREVHDFN
HHHHHHHHCCHHHHHCCCCEEEEEECCCEEECCCHHHHHHHCCEEEEEEECCCHHHHCCC
RPDAAGRGTYERVVPREQHFVASQGHRDYWVRGTYTRQNLDFTSDILHMVELGFRYLSME
CCCCCCCCCHHHCCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
PVVAAPEAEYAIKEEDLPRLAGEYRRLARIYLERARAGKGFSFFHFNIDAAAGPCLTKRL
CEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHH
TGCGAGTSYLAVTPAGDLYPCHQLVGRKDYCLGNVREGIRRPELREAFRQAYVYNQPACS
HCCCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
RCWARFYCSGGCHAANLAATGDLRQPAPIACAIQKMRLEAALYVQVKMAGKFC
HHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180918 [H]