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The map label for this gene is yvtA [H]

Identifier: 83591233

GI number: 83591233

Start: 2540004

End: 2541182

Strand: Reverse

Name: yvtA [H]

Synonym: Moth_2417

Alternate gene names: 83591233

Gene position: 2541182-2540004 (Counterclockwise)

Preceding gene: 83591234

Following gene: 83591232

Centisome position: 96.67

GC content: 57.59

Gene sequence:

>1179_bases
ATGGCGGCTGTCGCTCCCCGAGGAAACAAGGGGGTTGCCTTCTTGAAGCGCTTTTTTCCCGGCGGTTTGAGGCGCTACCG
GATACTCCTTCTGGTCTCATTAGTTTTTTTGAGTTCTATCCTGGGGGCGGGAGCCGCCCTCTATTTCGCACCGCGATTGA
TGTTCCGCCCCCTGCCACCAGCGTCCCCACCCCAAGGCTTGATTAACCAACCCGTAGGCTTGCCGGCCCAGTATACCGCC
GATTCACCGGTAGTCACTATTGCCCGGCAGGTGGGCCCTTCCGTCGTGGGGGTTCAGGCCATGACCGGTACCAATTATAC
TGGCGACGGCGTGGTAAAGCAGGGTTCGGGAGTAATCTTTGATACCACTAACGGCTATATTGTTACCAATAACCACGTTA
TTGCTGGCGCCGGTCGGATAACAGTCAGCCTGGACCGGGAGCAAACCTATCCGGCGACCCTGGTAGGTGCCGATGAGCGT
AGCGATCTGGCGGTATTAAAGGTCCAGGGGCCCAATCTCCCCCAGGCGCGCCTGGGGGATTCCAGCACCCTGCAGGTAGG
GGAAACTGTAGTAGCCATTGGTAACCCCCTGGGACGGGAGTTTGCCCGGTCGGTAACCGTAGGGGTAATCAGCGCTTTGA
ACCGGGAGGTAACAGTTCCCGGGTCCCGGGGTGTGGAGATAACCCTCCGTGTCCTCCAGACCGATGCCCCAATTAACCCT
GGCAACAGCGGCGGCGCCCTGGTTAACCTGCGAGGTGAGATTATCGGCATCAACAGCGTCAAGATTGCCGCCAGTGGTGT
CGAGGGAATGGGTTTCGCCATTCCCATAAACGACGTCCGGCCCATTATTGACCAGATAATCACCCGCGGCTATGTCACCC
ACCCCTTCCTGGGAGTTTATAACCTCCAGGAGATTACCCCGGAGATGGCCCAGTGGTATAATATACCTGTAGGCGTCTAT
GTCGGGGGTGTCTTCAAGGATGGCCCGGCAGCCAAGGCCGGCCTGCAGGTAGGAGATGTCATCACCGCCGTAGAGAACCA
GAAAGTCGCCACCTATGATGACATCCAGCGCCTGATCAATAAGAAATCCCCGGGGGATCAGGTGACGGTGACTATCCGGC
GCCTCAAGTCGCCAAACCCGGTCAACTACACTATAACCCTGGGGGAATTACCTAAATAG

Upstream 100 bases:

>100_bases
TTTTCGGGGAATGGCCCGGGAAAAGGAGTTATAAAGAAGGTAGCGCCAGGCAATATTAAAACTGATAACCAGGAAATCAT
CCGGCGGGGCGGGGCCTTTT

Downstream 100 bases:

>100_bases
GACGGGCGGCCTGATTGGGCAGGCCATCACAAAGCAGAGCCGCCTGGAGCGAAGCTATTTTTGGGGTACCATGCTCCCTT
CGCCGGGGCGCCCATGGTGA

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAAVAPRGNKGVAFLKRFFPGGLRRYRILLLVSLVFLSSILGAGAALYFAPRLMFRPLPPASPPQGLINQPVGLPAQYTA
DSPVVTIARQVGPSVVGVQAMTGTNYTGDGVVKQGSGVIFDTTNGYIVTNNHVIAGAGRITVSLDREQTYPATLVGADER
SDLAVLKVQGPNLPQARLGDSSTLQVGETVVAIGNPLGREFARSVTVGVISALNREVTVPGSRGVEITLRVLQTDAPINP
GNSGGALVNLRGEIIGINSVKIAASGVEGMGFAIPINDVRPIIDQIITRGYVTHPFLGVYNLQEITPEMAQWYNIPVGVY
VGGVFKDGPAAKAGLQVGDVITAVENQKVATYDDIQRLINKKSPGDQVTVTIRRLKSPNPVNYTITLGELPK

Sequences:

>Translated_392_residues
MAAVAPRGNKGVAFLKRFFPGGLRRYRILLLVSLVFLSSILGAGAALYFAPRLMFRPLPPASPPQGLINQPVGLPAQYTA
DSPVVTIARQVGPSVVGVQAMTGTNYTGDGVVKQGSGVIFDTTNGYIVTNNHVIAGAGRITVSLDREQTYPATLVGADER
SDLAVLKVQGPNLPQARLGDSSTLQVGETVVAIGNPLGREFARSVTVGVISALNREVTVPGSRGVEITLRVLQTDAPINP
GNSGGALVNLRGEIIGINSVKIAASGVEGMGFAIPINDVRPIIDQIITRGYVTHPFLGVYNLQEITPEMAQWYNIPVGVY
VGGVFKDGPAAKAGLQVGDVITAVENQKVATYDDIQRLINKKSPGDQVTVTIRRLKSPNPVNYTITLGELPK
>Mature_391_residues
AAVAPRGNKGVAFLKRFFPGGLRRYRILLLVSLVFLSSILGAGAALYFAPRLMFRPLPPASPPQGLINQPVGLPAQYTAD
SPVVTIARQVGPSVVGVQAMTGTNYTGDGVVKQGSGVIFDTTNGYIVTNNHVIAGAGRITVSLDREQTYPATLVGADERS
DLAVLKVQGPNLPQARLGDSSTLQVGETVVAIGNPLGREFARSVTVGVISALNREVTVPGSRGVEITLRVLQTDAPINPG
NSGGALVNLRGEIIGINSVKIAASGVEGMGFAIPINDVRPIIDQIITRGYVTHPFLGVYNLQEITPEMAQWYNIPVGVYV
GGVFKDGPAAKAGLQVGDVITAVENQKVATYDDIQRLINKKSPGDQVTVTIRRLKSPNPVNYTITLGELPK

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=306, Percent_Identity=32.6797385620915, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI22129776, Length=310, Percent_Identity=30.6451612903226, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI24308541, Length=295, Percent_Identity=32.8813559322034, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7019477, Length=309, Percent_Identity=31.3915857605178, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1789629, Length=339, Percent_Identity=35.1032448377581, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786356, Length=264, Percent_Identity=40.1515151515151, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789630, Length=346, Percent_Identity=35.5491329479769, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24646839, Length=292, Percent_Identity=37.3287671232877, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41394; Mature: 41263

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVAPRGNKGVAFLKRFFPGGLRRYRILLLVSLVFLSSILGAGAALYFAPRLMFRPLPP
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
ASPPQGLINQPVGLPAQYTADSPVVTIARQVGPSVVGVQAMTGTNYTGDGVVKQGSGVIF
CCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCEEEE
DTTNGYIVTNNHVIAGAGRITVSLDREQTYPATLVGADERSDLAVLKVQGPNLPQARLGD
ECCCCEEEECCEEEEECCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHCCC
SSTLQVGETVVAIGNPLGREFARSVTVGVISALNREVTVPGSRGVEITLRVLQTDAPINP
CCEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCCC
GNSGGALVNLRGEIIGINSVKIAASGVEGMGFAIPINDVRPIIDQIITRGYVTHPFLGVY
CCCCCEEEEECCEEEEECEEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
NLQEITPEMAQWYNIPVGVYVGGVFKDGPAAKAGLQVGDVITAVENQKVATYDDIQRLIN
CHHHCCHHHHHHCCCCEEEEECCEECCCCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHH
KKSPGDQVTVTIRRLKSPNPVNYTITLGELPK
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
AAVAPRGNKGVAFLKRFFPGGLRRYRILLLVSLVFLSSILGAGAALYFAPRLMFRPLPP
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
ASPPQGLINQPVGLPAQYTADSPVVTIARQVGPSVVGVQAMTGTNYTGDGVVKQGSGVIF
CCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCEEEE
DTTNGYIVTNNHVIAGAGRITVSLDREQTYPATLVGADERSDLAVLKVQGPNLPQARLGD
ECCCCEEEECCEEEEECCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHCCC
SSTLQVGETVVAIGNPLGREFARSVTVGVISALNREVTVPGSRGVEITLRVLQTDAPINP
CCEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCCC
GNSGGALVNLRGEIIGINSVKIAASGVEGMGFAIPINDVRPIIDQIITRGYVTHPFLGVY
CCCCCEEEEECCEEEEECEEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
NLQEITPEMAQWYNIPVGVYVGGVFKDGPAAKAGLQVGDVITAVENQKVATYDDIQRLIN
CHHHCCHHHHHHCCCCEEEEECCEECCCCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHH
KKSPGDQVTVTIRRLKSPNPVNYTITLGELPK
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10692364; 9353931; 9384377; 10568751; 11133960 [H]