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The map label for this gene is rho

Identifier: 83591218

GI number: 83591218

Start: 2521783

End: 2523072

Strand: Reverse

Name: rho

Synonym: Moth_2402

Alternate gene names: 83591218

Gene position: 2523072-2521783 (Counterclockwise)

Preceding gene: 83591219

Following gene: 83591217

Centisome position: 95.98

GC content: 58.29

Gene sequence:

>1290_bases
TTGAATACGGCCGAACTAGAAAGCAAGACCATGGTAGAGCTCTACCGGATAGCCCGCGAGTTAAACTTGAGCGGCTATTC
CCGGATGCGGAAAAAAGAGCTGGTATTTGAGATTGCCAAGGCCCTGGCCCAGAAAGAGCAGCAAGAACACCAGGAGGAGG
CCAGGGAAGAACAACTCCAGGCCCAGGGCATCCTGGAGATACTCCCGGATGGTTACGGATTTTTACGGCCCTTCGGCTAC
CTGGCCAGCGGCGACGATATCTACATCTCCGCCTCTCAAATCCGTCGCTTCGACCTGCGGACCGGGGATAAGGTGGCCGG
CCTGGTCCGGCCACCCAAGGACAATGAACGCTTTTTTGCCCTCCTGCGGGTGGAGAAGGTCAACGGGGAAAACCCGGAAA
CAGCAGCAGAACGCCTTCACTTTGATGCCCTGACCCCCATCTATCCCTCAGAGCGCTATACCCTGGAGACGGCCAACGGC
GACCCATCGGCCCGGATTATCGACCTGATAGCCCCTATAGGCAAAGGCCAGCGGGCCCTCATTGTCTCCCCGCCCAAAGC
CGGCAAGACGGTTCTGCTCAAGAAAATAGCCAACGCCATCAAGACCAACTACCCTGAAGTCGAATTGATGATCCTGCTAA
TCGACGAACGCCCGGAAGAGGTCACCGACATCGAGCGTTCGGTCCGGGGCGAGGTCATCAGTTCCACCTTTGACGAATTC
CCTGAAAACCACGTCAAAGTAGCTGACATGGTCCTGGAACGGGCTAAACGCTTGGTGGAGCATAAAAAGGATGTCGTAGT
TCTCCTGGACAGCATCACTCGCCTGGCCCGGGCCCACAACCTGGTTGTTCCCCCCAGCGGCCGCACCCTCTCCGGTGGCG
TCGATCCCACGGCTCTTTATAAACCCAAGCGCTTCTTCGGTGCCGCCCGGAACATCGAAGAGGGTGGCAGCCTGACCATT
GTGGCCACCGCCCTGATTGAGACCGGCAGCCGCATGGACGAGGTTATTTTCGAAGAATTTAAAGGCACCGGTAATATGGA
ACTCATCCTGGACCGGAGGTTGGCCGAGCGGCGGATTTTCCCGGCCATCGATGTTAAACGTTCCGGCACGCGGCGGGAGG
AATTGCTCCTCAGCCGGGAGGAGCTGGAACTGGTCTGGAACTTCCGGCGGGTGAGCAGCGGAATGGGCCCGGTAGAGGTC
ACCGAGACCCTCATCGACGCCATGAAGAAAACCAAGAGTAACCAGGACCTCCTGCGCGCCCTCCCCGCCCTTTTCCCCCG
GGAACATTAA

Upstream 100 bases:

>100_bases
GACACCGGCCTGGCACGCTTCCTGGCAGACTGGGAAAAGGTAAAGAATAAGTAACCCCTTCTCCCCTGCCGCCGGCCGCG
ATTACGGAGGTTTAAGCTAT

Downstream 100 bases:

>100_bases
TAAAGACCTCCTGGAAGCAACTCTGCAAGAAATCCCGGCCACTCCGGGCTGCCCCTGTTGTGCAGCCCCGGCAGTGGGCG
GGTATATTTTTGCTAAGGTA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNTAELESKTMVELYRIARELNLSGYSRMRKKELVFEIAKALAQKEQQEHQEEAREEQLQAQGILEILPDGYGFLRPFGY
LASGDDIYISASQIRRFDLRTGDKVAGLVRPPKDNERFFALLRVEKVNGENPETAAERLHFDALTPIYPSERYTLETANG
DPSARIIDLIAPIGKGQRALIVSPPKAGKTVLLKKIANAIKTNYPEVELMILLIDERPEEVTDIERSVRGEVISSTFDEF
PENHVKVADMVLERAKRLVEHKKDVVVLLDSITRLARAHNLVVPPSGRTLSGGVDPTALYKPKRFFGAARNIEEGGSLTI
VATALIETGSRMDEVIFEEFKGTGNMELILDRRLAERRIFPAIDVKRSGTRREELLLSREELELVWNFRRVSSGMGPVEV
TETLIDAMKKTKSNQDLLRALPALFPREH

Sequences:

>Translated_429_residues
MNTAELESKTMVELYRIARELNLSGYSRMRKKELVFEIAKALAQKEQQEHQEEAREEQLQAQGILEILPDGYGFLRPFGY
LASGDDIYISASQIRRFDLRTGDKVAGLVRPPKDNERFFALLRVEKVNGENPETAAERLHFDALTPIYPSERYTLETANG
DPSARIIDLIAPIGKGQRALIVSPPKAGKTVLLKKIANAIKTNYPEVELMILLIDERPEEVTDIERSVRGEVISSTFDEF
PENHVKVADMVLERAKRLVEHKKDVVVLLDSITRLARAHNLVVPPSGRTLSGGVDPTALYKPKRFFGAARNIEEGGSLTI
VATALIETGSRMDEVIFEEFKGTGNMELILDRRLAERRIFPAIDVKRSGTRREELLLSREELELVWNFRRVSSGMGPVEV
TETLIDAMKKTKSNQDLLRALPALFPREH
>Mature_429_residues
MNTAELESKTMVELYRIARELNLSGYSRMRKKELVFEIAKALAQKEQQEHQEEAREEQLQAQGILEILPDGYGFLRPFGY
LASGDDIYISASQIRRFDLRTGDKVAGLVRPPKDNERFFALLRVEKVNGENPETAAERLHFDALTPIYPSERYTLETANG
DPSARIIDLIAPIGKGQRALIVSPPKAGKTVLLKKIANAIKTNYPEVELMILLIDERPEEVTDIERSVRGEVISSTFDEF
PENHVKVADMVLERAKRLVEHKKDVVVLLDSITRLARAHNLVVPPSGRTLSGGVDPTALYKPKRFFGAARNIEEGGSLTI
VATALIETGSRMDEVIFEEFKGTGNMELILDRRLAERRIFPAIDVKRSGTRREELLLSREELELVWNFRRVSSGMGPVEV
TETLIDAMKKTKSNQDLLRALPALFPREH

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=426, Percent_Identity=56.1032863849765, Blast_Score=489, Evalue=1e-140,
Organism=Escherichia coli, GI1788251, Length=295, Percent_Identity=26.7796610169492, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 48414; Mature: 48414

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAELESKTMVELYRIARELNLSGYSRMRKKELVFEIAKALAQKEQQEHQEEAREEQLQ
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGILEILPDGYGFLRPFGYLASGDDIYISASQIRRFDLRTGDKVAGLVRPPKDNERFFA
HHHHHHHCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
LLRVEKVNGENPETAAERLHFDALTPIYPSERYTLETANGDPSARIIDLIAPIGKGQRAL
EEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEE
IVSPPKAGKTVLLKKIANAIKTNYPEVELMILLIDERPEEVTDIERSVRGEVISSTFDEF
EECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
PENHVKVADMVLERAKRLVEHKKDVVVLLDSITRLARAHNLVVPPSGRTLSGGVDPTALY
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEECCCCCEECCCCCCHHHC
KPKRFFGAARNIEEGGSLTIVATALIETGSRMDEVIFEEFKGTGNMELILDRRLAERRIF
CCHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCC
PAIDVKRSGTRREELLLSREELELVWNFRRVSSGMGPVEVTETLIDAMKKTKSNQDLLRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LPALFPREH
HHHHCCCCC
>Mature Secondary Structure
MNTAELESKTMVELYRIARELNLSGYSRMRKKELVFEIAKALAQKEQQEHQEEAREEQLQ
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGILEILPDGYGFLRPFGYLASGDDIYISASQIRRFDLRTGDKVAGLVRPPKDNERFFA
HHHHHHHCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
LLRVEKVNGENPETAAERLHFDALTPIYPSERYTLETANGDPSARIIDLIAPIGKGQRAL
EEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEE
IVSPPKAGKTVLLKKIANAIKTNYPEVELMILLIDERPEEVTDIERSVRGEVISSTFDEF
EECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
PENHVKVADMVLERAKRLVEHKKDVVVLLDSITRLARAHNLVVPPSGRTLSGGVDPTALY
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEECCCCCEECCCCCCHHHC
KPKRFFGAARNIEEGGSLTIVATALIETGSRMDEVIFEEFKGTGNMELILDRRLAERRIF
CCHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCC
PAIDVKRSGTRREELLLSREELELVWNFRRVSSGMGPVEVTETLIDAMKKTKSNQDLLRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LPALFPREH
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]