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The map label for this gene is atpB

Identifier: 83591200

GI number: 83591200

Start: 2508337

End: 2508993

Strand: Reverse

Name: atpB

Synonym: Moth_2384

Alternate gene names: 83591200

Gene position: 2508993-2508337 (Counterclockwise)

Preceding gene: 83591201

Following gene: 83591199

Centisome position: 95.44

GC content: 50.84

Gene sequence:

>657_bases
ATGACCCATGTCCGCCCGGTTGAAATCTTTCACCTGGGACCTATCCCCATCTATTCTACGGTGGTCAACACCTGGATTAT
TATGATCCTGCTGCTGGCCGGGATCTTCCTGGCGACCAGGAAACTCAGTTTTATCCCGCGGGGGGCCCAGCATGTCCTGG
AGATGTTCCTGGAGTTCTTCTACGGGCTCCTGGAAGAAATCATAGGCAAAGAAGGGCGGCGTTATCTCCCTCTGGTTGCT
ACCCTCTTTATCTTTATTTTAAGCCTGAATCTATCATGGTTTATCCCGGGGATGAAACCGCCTACCATGGACCTCTCCAC
CACGGCGGCCTTTGCGGTGACGACCATTATCCTGGTCCAGATTTTCGGCATCCGCAAACTGGGGCTGCGGGGGTACATCC
GCCATTTTTTCCAGCCGGCGCCATTTCTTTTTCCTTTAAACGTTATCGAAGAACTGGTCAAACCGGTATCCCTTTCCCTC
CGTCTTTTCGGCAATTTGTTTGGCGAAGAGATGGTGGTTACCATTTTATTTCTGATGATACCCTTCCTGTTGCCGACCCC
CATTATGCTTCTGGGGGTTCTGATGGGTACCATCCAGGCTTTTGTATTTACCCTGTTGACTATTACCTATATCGCCAACT
TTGTCCACGGGCACTGA

Upstream 100 bases:

>100_bases
GGCCTGTTCCTCCAGGTCGCCGCTTACATGGGCCAGGCAGCCCTGATTATCCTGAGAAAGGAGGGGAAGAAAGTTGGGAC
TTCGGGCTCTGGGCGAGATC

Downstream 100 bases:

>100_bases
GTGGCTGTAAACGTTAGCATGGGTAAAAACAGGTTGTATAGCCCAAAGGGCTTTTTCTTAAACTGAGTTTTATATTTTCA
AAGGAGGAGACATATGGCAA

Product: ATP synthase F0, A subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTHVRPVEIFHLGPIPIYSTVVNTWIIMILLLAGIFLATRKLSFIPRGAQHVLEMFLEFFYGLLEEIIGKEGRRYLPLVA
TLFIFILSLNLSWFIPGMKPPTMDLSTTAAFAVTTIILVQIFGIRKLGLRGYIRHFFQPAPFLFPLNVIEELVKPVSLSL
RLFGNLFGEEMVVTILFLMIPFLLPTPIMLLGVLMGTIQAFVFTLLTITYIANFVHGH

Sequences:

>Translated_218_residues
MTHVRPVEIFHLGPIPIYSTVVNTWIIMILLLAGIFLATRKLSFIPRGAQHVLEMFLEFFYGLLEEIIGKEGRRYLPLVA
TLFIFILSLNLSWFIPGMKPPTMDLSTTAAFAVTTIILVQIFGIRKLGLRGYIRHFFQPAPFLFPLNVIEELVKPVSLSL
RLFGNLFGEEMVVTILFLMIPFLLPTPIMLLGVLMGTIQAFVFTLLTITYIANFVHGH
>Mature_217_residues
THVRPVEIFHLGPIPIYSTVVNTWIIMILLLAGIFLATRKLSFIPRGAQHVLEMFLEFFYGLLEEIIGKEGRRYLPLVAT
LFIFILSLNLSWFIPGMKPPTMDLSTTAAFAVTTIILVQIFGIRKLGLRGYIRHFFQPAPFLFPLNVIEELVKPVSLSLR
LFGNLFGEEMVVTILFLMIPFLLPTPIMLLGVLMGTIQAFVFTLLTITYIANFVHGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=210, Percent_Identity=27.1428571428571, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_MOOTA (Q2RFX3)

Other databases:

- EMBL:   U64318
- EMBL:   CP000232
- RefSeq:   YP_431209.1
- ProteinModelPortal:   Q2RFX3
- SMR:   Q2RFX3
- STRING:   Q2RFX3
- GeneID:   3832023
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2384
- NMPDR:   fig|264732.9.peg.2416
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- PhylomeDB:   Q2RFX3
- BioCyc:   MTHE264732:MOTH_2384-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 24724; Mature: 24592

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x111d6d04)-; HASH(0x11753368)-; HASH(0x111c95fc)-; HASH(0x11774c48)-; HASH(0x1174746c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVRPVEIFHLGPIPIYSTVVNTWIIMILLLAGIFLATRKLSFIPRGAQHVLEMFLEFF
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YGLLEEIIGKEGRRYLPLVATLFIFILSLNLSWFIPGMKPPTMDLSTTAAFAVTTIILVQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IFGIRKLGLRGYIRHFFQPAPFLFPLNVIEELVKPVSLSLRLFGNLFGEEMVVTILFLMI
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLLPTPIMLLGVLMGTIQAFVFTLLTITYIANFVHGH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
THVRPVEIFHLGPIPIYSTVVNTWIIMILLLAGIFLATRKLSFIPRGAQHVLEMFLEFF
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YGLLEEIIGKEGRRYLPLVATLFIFILSLNLSWFIPGMKPPTMDLSTTAAFAVTTIILVQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IFGIRKLGLRGYIRHFFQPAPFLFPLNVIEELVKPVSLSLRLFGNLFGEEMVVTILFLMI
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLLPTPIMLLGVLMGTIQAFVFTLLTITYIANFVHGH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA