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The map label for this gene is murA2 [H]

Identifier: 83591191

GI number: 83591191

Start: 2500395

End: 2501654

Strand: Reverse

Name: murA2 [H]

Synonym: Moth_2375

Alternate gene names: 83591191

Gene position: 2501654-2500395 (Counterclockwise)

Preceding gene: 83591192

Following gene: 83591190

Centisome position: 95.16

GC content: 60.56

Gene sequence:

>1260_bases
TTGGAGGCTATAGCTATTCAGGGCCGGGCGCGGTTGCGTGGCCGAGTGGCCATCAGCGGCTCCAAGAATGCCGTCCTGCC
GATTATTGCGGCCTGCCTGCTGACTGGTGACGAGTGCTATCTGGAAGATATCCCCCGGCTGGCTGATGTTGATACCATGT
GCGGAGTCATCGGTGAACTGGGCGCCAGGGTTTATCCTGAGGGGATAAATGGCCTGCGCATCAGTTCCGGCTTTTTAGAA
AAGGTGGAACCCCCCTACGAATACGTCCGCCGCATGCGGGCCTCCTTTCTGGTCATGGGCCCCCTCTTGGCCCGTTTTGG
GCGGGTAAAGGTTTCTCTGCCGGGAGGGTGCGCCATCGGTGCCCGACCCATTGACCTGCACCTGAAGGGTATGGCCGCCC
TGGGGGCCAAGATTACTGTTAATAAAGGTAACGTTGAGGCCGAGGCTGGCAGCCGCCTGAAGGGAGCCCAGGTATACCTG
GATTTCCCCAGTGTCGGAGCGACGGAGAATATCATGATGGCCGCCGCCCTGGCCGAGGGGACTACCACCATCGAAAACGC
CGCCGGCGAACCGGAGATCGTTGACCTGGCCAACTTCATCAACGCCATGGGCGGCCGGGTCACAGGCGCCGGGACCAGGG
TTATCAAAATCGAGGGGGTAAAGGAACTCCACGGCAGCCGTCATGCCGTTATCCCCGACCGGGTTGAAGCCGGCACCTTT
ATGATTGCCGCCGCCGCCACCGGCGGGGATGTTTTGGTGGAAAATGTAATCCCCACCCACCTGAAGGCGGTCATGGCCAA
ACTGGCCGAAACCGGCGCCCGGCTGGAAGAGGAAGAGGGCGGCATTCGGGTGCGGGCCGATCTACCCTTAAAGGCAGTTG
ACATCAAGACCATGCCCTATCCCGGCTTCCCGACGGACATGCAGGCCCAGTTCATGGCCCTCCTGACCACCGCCCGGGGG
AGCAGCATGGTCACAGAGACCGTCTTTGAAAACCGCTTTATGCACGTCAACGAGCTGAAACGCATGGGGGCCGATATAGT
CATAGAAGGCCATTGCGCCGTGATTAAAGGCAAGAGCAAGCTCATCGGGGCGCCCGTCAAGGCTACCGACCTGCGGGCCG
GGGCGGCCCTGGTCATTGCCGGCCTCATGGCTGAGGGAGAAACAACCATCTCCTGCGTCCACCATATTGACCGCGGCTAC
GAAAACCTGGTCGGCAAGCTCCAGGCCCTGGGCGCTGAAGTTATCAGAACAGAAATTTAG

Upstream 100 bases:

>100_bases
TTACACCTCGGCTCACCCCTTTTAGGTGGCGAGTACTAAAAAAACCATGTTATAATAAACCTTGACTATAGAGACGAAAA
ATTAAAAGGGGCTAGGGAAA

Downstream 100 bases:

>100_bases
AGAGCCTCTCATGGGTCAGCCTGTCAGTTTTCGTATTCTACCGCCTCGCCCGGGGCGGTCTTTTTTTGGCCAAGCCTTCA
TATATATATGGACATGACAG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MEAIAIQGRARLRGRVAISGSKNAVLPIIAACLLTGDECYLEDIPRLADVDTMCGVIGELGARVYPEGINGLRISSGFLE
KVEPPYEYVRRMRASFLVMGPLLARFGRVKVSLPGGCAIGARPIDLHLKGMAALGAKITVNKGNVEAEAGSRLKGAQVYL
DFPSVGATENIMMAAALAEGTTTIENAAGEPEIVDLANFINAMGGRVTGAGTRVIKIEGVKELHGSRHAVIPDRVEAGTF
MIAAAATGGDVLVENVIPTHLKAVMAKLAETGARLEEEEGGIRVRADLPLKAVDIKTMPYPGFPTDMQAQFMALLTTARG
SSMVTETVFENRFMHVNELKRMGADIVIEGHCAVIKGKSKLIGAPVKATDLRAGAALVIAGLMAEGETTISCVHHIDRGY
ENLVGKLQALGAEVIRTEI

Sequences:

>Translated_419_residues
MEAIAIQGRARLRGRVAISGSKNAVLPIIAACLLTGDECYLEDIPRLADVDTMCGVIGELGARVYPEGINGLRISSGFLE
KVEPPYEYVRRMRASFLVMGPLLARFGRVKVSLPGGCAIGARPIDLHLKGMAALGAKITVNKGNVEAEAGSRLKGAQVYL
DFPSVGATENIMMAAALAEGTTTIENAAGEPEIVDLANFINAMGGRVTGAGTRVIKIEGVKELHGSRHAVIPDRVEAGTF
MIAAAATGGDVLVENVIPTHLKAVMAKLAETGARLEEEEGGIRVRADLPLKAVDIKTMPYPGFPTDMQAQFMALLTTARG
SSMVTETVFENRFMHVNELKRMGADIVIEGHCAVIKGKSKLIGAPVKATDLRAGAALVIAGLMAEGETTISCVHHIDRGY
ENLVGKLQALGAEVIRTEI
>Mature_419_residues
MEAIAIQGRARLRGRVAISGSKNAVLPIIAACLLTGDECYLEDIPRLADVDTMCGVIGELGARVYPEGINGLRISSGFLE
KVEPPYEYVRRMRASFLVMGPLLARFGRVKVSLPGGCAIGARPIDLHLKGMAALGAKITVNKGNVEAEAGSRLKGAQVYL
DFPSVGATENIMMAAALAEGTTTIENAAGEPEIVDLANFINAMGGRVTGAGTRVIKIEGVKELHGSRHAVIPDRVEAGTF
MIAAAATGGDVLVENVIPTHLKAVMAKLAETGARLEEEEGGIRVRADLPLKAVDIKTMPYPGFPTDMQAQFMALLTTARG
SSMVTETVFENRFMHVNELKRMGADIVIEGHCAVIKGKSKLIGAPVKATDLRAGAALVIAGLMAEGETTISCVHHIDRGY
ENLVGKLQALGAEVIRTEI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=50.2380952380952, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44304; Mature: 44304

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIAIQGRARLRGRVAISGSKNAVLPIIAACLLTGDECYLEDIPRLADVDTMCGVIGEL
CCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHH
GARVYPEGINGLRISSGFLEKVEPPYEYVRRMRASFLVMGPLLARFGRVKVSLPGGCAIG
CCEECCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEC
ARPIDLHLKGMAALGAKITVNKGNVEAEAGSRLKGAQVYLDFPSVGATENIMMAAALAEG
CCEEEEEEECHHHCCCEEEEECCCEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
TTTIENAAGEPEIVDLANFINAMGGRVTGAGTRVIKIEGVKELHGSRHAVIPDRVEAGTF
CCHHHCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCEE
MIAAAATGGDVLVENVIPTHLKAVMAKLAETGARLEEEEGGIRVRADLPLKAVDIKTMPY
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECCC
PGFPTDMQAQFMALLTTARGSSMVTETVFENRFMHVNELKRMGADIVIEGHCAVIKGKSK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEECCEEEEECCCC
LIGAPVKATDLRAGAALVIAGLMAEGETTISCVHHIDRGYENLVGKLQALGAEVIRTEI
EECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEAIAIQGRARLRGRVAISGSKNAVLPIIAACLLTGDECYLEDIPRLADVDTMCGVIGEL
CCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHH
GARVYPEGINGLRISSGFLEKVEPPYEYVRRMRASFLVMGPLLARFGRVKVSLPGGCAIG
CCEECCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEC
ARPIDLHLKGMAALGAKITVNKGNVEAEAGSRLKGAQVYLDFPSVGATENIMMAAALAEG
CCEEEEEEECHHHCCCEEEEECCCEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
TTTIENAAGEPEIVDLANFINAMGGRVTGAGTRVIKIEGVKELHGSRHAVIPDRVEAGTF
CCHHHCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCEE
MIAAAATGGDVLVENVIPTHLKAVMAKLAETGARLEEEEGGIRVRADLPLKAVDIKTMPY
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECCC
PGFPTDMQAQFMALLTTARGSSMVTETVFENRFMHVNELKRMGADIVIEGHCAVIKGKSK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEECCEEEEECCCC
LIGAPVKATDLRAGAALVIAGLMAEGETTISCVHHIDRGYENLVGKLQALGAEVIRTEI
EECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA