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The map label for this gene is fadR [H]

Identifier: 83591184

GI number: 83591184

Start: 2491585

End: 2492178

Strand: Reverse

Name: fadR [H]

Synonym: Moth_2368

Alternate gene names: 83591184

Gene position: 2492178-2491585 (Counterclockwise)

Preceding gene: 83591185

Following gene: 83591183

Centisome position: 94.8

GC content: 57.41

Gene sequence:

>594_bases
ATGAGCCGCGAAGCCGGGGATAAACGCCGGCAGATCCTGGCGGCGGCCGTGTCGGTTTTTGCCGACCGGGGCTTCCACCA
GGCCAGGATCGCCGATATTGCCGCTGCCGCCGGGGTAGGGAAGGGGACCATCTATGAGTATTTCTCCAGCAAAAAGGAAC
TCTTCCAGCAATTGCTAGTTCATATCTTCCACACTTACCTGGAGCACCTGCGCCGGGTATGCCGGGAAGAAGCAAGCCTG
GAAGGCTTCCTGCGGCGGCTGATCGGCGAAAGCCTGGAACACTTCCAGGCTCACCGGGAAATTACCAGAATTCTTTTGAG
CGAACACCCGCCGGTGGATGCCGCCACCCAGCAGATATTCTTCAGGATGGAGCATGAAAAACTGCAACACCTGCAAAATC
ACCTGCAAGCGGCCCTTGAGCGGGGGGAAATGCGCCCGGTGCCGGCGGACCTGGCGGCTATTATGATCACTGGTTTCATA
ACCGCCCTGGGGTACCAGTTATTCTTCTATAGGAATCAGGAAATGAACCTGGCGGCTTTGTCAACGGGGGTTACAGATCT
CATCTTACGGGGTATCCGGGATAGCGGCGGGTGA

Upstream 100 bases:

>100_bases
CAAGTCGGCAGGAGGAGCCCTTCAGGCGCCCGGACGTAACCGGCGCCTGAAGGGAGCCGGCCAGCCGGCCCGGCCGGCAT
GAGAGAGGGGGAGAGGGAGG

Downstream 100 bases:

>100_bases
CCGGCCGTCGCGATATATCAGGGTAACCGCTCCGATCCGGCAGCCATGGCCGACGTTTCTTTACTACCTGGACCAGGTCG
ACTGATCCCGACCAAACTGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSREAGDKRRQILAAAVSVFADRGFHQARIADIAAAAGVGKGTIYEYFSSKKELFQQLLVHIFHTYLEHLRRVCREEASL
EGFLRRLIGESLEHFQAHREITRILLSEHPPVDAATQQIFFRMEHEKLQHLQNHLQAALERGEMRPVPADLAAIMITGFI
TALGYQLFFYRNQEMNLAALSTGVTDLILRGIRDSGG

Sequences:

>Translated_197_residues
MSREAGDKRRQILAAAVSVFADRGFHQARIADIAAAAGVGKGTIYEYFSSKKELFQQLLVHIFHTYLEHLRRVCREEASL
EGFLRRLIGESLEHFQAHREITRILLSEHPPVDAATQQIFFRMEHEKLQHLQNHLQAALERGEMRPVPADLAAIMITGFI
TALGYQLFFYRNQEMNLAALSTGVTDLILRGIRDSGG
>Mature_196_residues
SREAGDKRRQILAAAVSVFADRGFHQARIADIAAAAGVGKGTIYEYFSSKKELFQQLLVHIFHTYLEHLRRVCREEASLE
GFLRRLIGESLEHFQAHREITRILLSEHPPVDAATQQIFFRMEHEKLQHLQNHLQAALERGEMRPVPADLAAIMITGFIT
ALGYQLFFYRNQEMNLAALSTGVTDLILRGIRDSGG

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22329; Mature: 22198

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREAGDKRRQILAAAVSVFADRGFHQARIADIAAAAGVGKGTIYEYFSSKKELFQQLLV
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HIFHTYLEHLRRVCREEASLEGFLRRLIGESLEHFQAHREITRILLSEHPPVDAATQQIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FRMEHEKLQHLQNHLQAALERGEMRPVPADLAAIMITGFITALGYQLFFYRNQEMNLAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHH
STGVTDLILRGIRDSGG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SREAGDKRRQILAAAVSVFADRGFHQARIADIAAAAGVGKGTIYEYFSSKKELFQQLLV
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HIFHTYLEHLRRVCREEASLEGFLRRLIGESLEHFQAHREITRILLSEHPPVDAATQQIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FRMEHEKLQHLQNHLQAALERGEMRPVPADLAAIMITGFITALGYQLFFYRNQEMNLAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHH
STGVTDLILRGIRDSGG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]