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The map label for this gene is macB [H]

Identifier: 83591172

GI number: 83591172

Start: 2473344

End: 2474570

Strand: Reverse

Name: macB [H]

Synonym: Moth_2353

Alternate gene names: 83591172

Gene position: 2474570-2473344 (Counterclockwise)

Preceding gene: 83591173

Following gene: 83591170

Centisome position: 94.13

GC content: 61.04

Gene sequence:

>1227_bases
GTGGACCTTTATGCCGCTCTGACAGTCGCCTGGCGGGGGTTGCTGGCCAACAAGATGCGCTCAATTTTAACCATGCTGGG
GATTATCATAGGCGTGGCAGCCGTGATCATCATGATCAGCATCGGCCAGGGGGCCTCGGCCCAGGTAACAAGCAGGATAG
CCAGTATGGGCTCCAACCTGATCATGGTCATGCCGGCAGCTTCTTTCGGGGCCGTCCGGGGTGCCGGCGGTGAGGTCAAT
TCCCTGACCCTGGACGACGCCAGGGCTATAGGAGAGCTTCCTTTGGTGCAAAACGTGGCCCCCGAGGCCAGGAGCCAGGT
TACCGCTTCTTTCGGCAGCAGGACCTGGACCACCACCGTTAACGGCACCACGGCGGGGTTGCAGGCTATCAAAGGCTGGC
AGATGACTGCCGGCGCTTTCTTTTCCAATGACGACGTAGACCGCGCCGCCCTGGTGGCTGTGCTGGGACCGACGGTAGTG
GCCAATCTTTTCCCCTCCGGTTTTAACCCCATAGGCGCTTCCATTACTTTAAATAACTTGCAGTTCACGGTCATTGGCAT
CCTGCCGTCCCAGGGAAGCGGCTTCGGCGGTGCGGACCAGGACGATATAATCTATATCCCCATCACGACGGCCCAGCGGC
GTTTTCTCGGCCAGGGGGTAGTACCCAATAGCGTGCGGATGATTAATGTCCAGGCCCAGGACACCACCAGCTTGACTGCT
GTCCAGGAGGAGATCACCTCCCTCCTGCGGCAGCGCCACCACCTGGGGGCCAACCAGGACGACGACTTTCGCATCCAGAA
TATGACCGCCGTCCTGGACACCGTGGCCGCGGCTACCGGCAGCATGACCCTGTTGCTGGCCGGTATAGCCGCCGTCTCCC
TCCTGGTCGGCGGCATCGGCATCATGAATATCATGCTGGTGTCGGTAACCGAGCGCACCAGGGAGATCGGCATTCGCATG
GCCGTGGGAGCCACCAGGGGCGCCATCCTCACCCAATTTCTGGTGGAAGCCATGATCTTGAGCCTGGTGGGCGGCCTGAT
CGGTGTCGCCGGGGGTATTATAGGCAGCAAGGTTGTTGCCATGCTGGCCAAGTGGCCGGCGGTCCTCAACCCCATGGCTA
TCCTGCTGGCGATGGGCTTTGCCGCCCTGGTGGGGATCTTTTTCGGTTATTACCCCGCCCGGAAAGCCGCCAATGCCGAC
CCCATCGAGGCCCTGCGCTTTGAGTGA

Upstream 100 bases:

>100_bases
GCGTATCCGTGACGGCCAGATAATAGAAGATCGGCCCGTGCCGGAGCCGCGCCTGGCCGCCCGGGAACTGGCAGCATTAC
CGGTAGAGGAGGATTAGAAA

Downstream 100 bases:

>100_bases
GTTAAGATTCCCTGCAGATGGCCGCAAAAACTCCAGTTAGCCGAACGCTAAAAGCTCCAACCAAGGTACTGAACGATGTA
GCGGGCATACTGACGAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MDLYAALTVAWRGLLANKMRSILTMLGIIIGVAAVIIMISIGQGASAQVTSRIASMGSNLIMVMPAASFGAVRGAGGEVN
SLTLDDARAIGELPLVQNVAPEARSQVTASFGSRTWTTTVNGTTAGLQAIKGWQMTAGAFFSNDDVDRAALVAVLGPTVV
ANLFPSGFNPIGASITLNNLQFTVIGILPSQGSGFGGADQDDIIYIPITTAQRRFLGQGVVPNSVRMINVQAQDTTSLTA
VQEEITSLLRQRHHLGANQDDDFRIQNMTAVLDTVAAATGSMTLLLAGIAAVSLLVGGIGIMNIMLVSVTERTREIGIRM
AVGATRGAILTQFLVEAMILSLVGGLIGVAGGIIGSKVVAMLAKWPAVLNPMAILLAMGFAALVGIFFGYYPARKAANAD
PIEALRFE

Sequences:

>Translated_408_residues
MDLYAALTVAWRGLLANKMRSILTMLGIIIGVAAVIIMISIGQGASAQVTSRIASMGSNLIMVMPAASFGAVRGAGGEVN
SLTLDDARAIGELPLVQNVAPEARSQVTASFGSRTWTTTVNGTTAGLQAIKGWQMTAGAFFSNDDVDRAALVAVLGPTVV
ANLFPSGFNPIGASITLNNLQFTVIGILPSQGSGFGGADQDDIIYIPITTAQRRFLGQGVVPNSVRMINVQAQDTTSLTA
VQEEITSLLRQRHHLGANQDDDFRIQNMTAVLDTVAAATGSMTLLLAGIAAVSLLVGGIGIMNIMLVSVTERTREIGIRM
AVGATRGAILTQFLVEAMILSLVGGLIGVAGGIIGSKVVAMLAKWPAVLNPMAILLAMGFAALVGIFFGYYPARKAANAD
PIEALRFE
>Mature_408_residues
MDLYAALTVAWRGLLANKMRSILTMLGIIIGVAAVIIMISIGQGASAQVTSRIASMGSNLIMVMPAASFGAVRGAGGEVN
SLTLDDARAIGELPLVQNVAPEARSQVTASFGSRTWTTTVNGTTAGLQAIKGWQMTAGAFFSNDDVDRAALVAVLGPTVV
ANLFPSGFNPIGASITLNNLQFTVIGILPSQGSGFGGADQDDIIYIPITTAQRRFLGQGVVPNSVRMINVQAQDTTSLTA
VQEEITSLLRQRHHLGANQDDDFRIQNMTAVLDTVAAATGSMTLLLAGIAAVSLLVGGIGIMNIMLVSVTERTREIGIRM
AVGATRGAILTQFLVEAMILSLVGGLIGVAGGIIGSKVVAMLAKWPAVLNPMAILLAMGFAALVGIFFGYYPARKAANAD
PIEALRFE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=404, Percent_Identity=37.8712871287129, Blast_Score=231, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42458; Mature: 42458

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYAALTVAWRGLLANKMRSILTMLGIIIGVAAVIIMISIGQGASAQVTSRIASMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCE
IMVMPAASFGAVRGAGGEVNSLTLDDARAIGELPLVQNVAPEARSQVTASFGSRTWTTTV
EEEEECCCCCCCCCCCCCCCEEECHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCEEEEEE
NGTTAGLQAIKGWQMTAGAFFSNDDVDRAALVAVLGPTVVANLFPSGFNPIGASITLNNL
CCCHHHHHHHCCCEEECCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
QFTVIGILPSQGSGFGGADQDDIIYIPITTAQRRFLGQGVVPNSVRMINVQAQDTTSLTA
EEEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHH
VQEEITSLLRQRHHLGANQDDDFRIQNMTAVLDTVAAATGSMTLLLAGIAAVSLLVGGIG
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVTERTREIGIRMAVGATRGAILTQFLVEAMILSLVGGLIGVAGGIIGSKVVA
HHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAKWPAVLNPMAILLAMGFAALVGIFFGYYPARKAANADPIEALRFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCC
>Mature Secondary Structure
MDLYAALTVAWRGLLANKMRSILTMLGIIIGVAAVIIMISIGQGASAQVTSRIASMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCE
IMVMPAASFGAVRGAGGEVNSLTLDDARAIGELPLVQNVAPEARSQVTASFGSRTWTTTV
EEEEECCCCCCCCCCCCCCCEEECHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCEEEEEE
NGTTAGLQAIKGWQMTAGAFFSNDDVDRAALVAVLGPTVVANLFPSGFNPIGASITLNNL
CCCHHHHHHHCCCEEECCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
QFTVIGILPSQGSGFGGADQDDIIYIPITTAQRRFLGQGVVPNSVRMINVQAQDTTSLTA
EEEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHH
VQEEITSLLRQRHHLGANQDDDFRIQNMTAVLDTVAAATGSMTLLLAGIAAVSLLVGGIG
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVTERTREIGIRMAVGATRGAILTQFLVEAMILSLVGGLIGVAGGIIGSKVVA
HHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAKWPAVLNPMAILLAMGFAALVGIFFGYYPARKAANADPIEALRFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA