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The map label for this gene is lutB [H]

Identifier: 83591126

GI number: 83591126

Start: 2422717

End: 2424909

Strand: Reverse

Name: lutB [H]

Synonym: Moth_2305

Alternate gene names: 83591126

Gene position: 2424909-2422717 (Counterclockwise)

Preceding gene: 83591127

Following gene: 83591125

Centisome position: 92.24

GC content: 59.87

Gene sequence:

>2193_bases
GTGGCCGGTAAAGAATTCAAGCAACGTATCCGGCAGGCCCTGAATAACGCCAGCCTGCGGGGAGCCCTTGGTCGCTTTGC
CGATTCCTATGTAGTTTCCCGGGAAGAGGTTTATGCCGGCCGGGATTTTGAATCCTTAAGGCAGAGGATTGCCGCTATCA
AGGCTGATGCCGCCGGCCGTTACGAGGAACTGGCCGACCGGTTCAGCCGGGCGGTGGAGGCCCGAGGCGGCAAGGTGTTC
CGAGCTAAGGACGCAGCGGCCGCCAGGGAATATATCTACCAGGTAGCTAAAGAACACGGCGTTACAGAAATCGTCAAGTC
CAAGTCCTTTGCTTCGGAAGAGATCCACCTGAACGAATTCCTCCAGGAACGGGGTATCAATCCCTACGAAACCGACCTGG
CCGAGTGGATCCTCCAGCTCATGCCCGGGGAGAGGCCTTCCCATATGGTCATGCCGGCCATTCACCTCCCCAAGGAGGAG
GTCGCCCGGGTCTTCAGCCGTTACCTGGGTGAACCGGTAGAACCTGATATTAAAAATATGGTCCGTATCGCCCGCCGGGA
GTTGAGGAAAAAATTTCTGACTGCCGGCATGGGCATCAGCGGCGCCAACATTGCCGTGGCTGAAACGGGGACCATTGTCC
TCTGCACCAATGAAGGCAACGCCCGCTTGACTACTACTGTACCACCGGTTCACGTGGCCATTGTCGGCTACGAGAAGCTG
GTGCCCAGCATTAAAGATATTGTTCCCATCCTTGAGGCCCTGCCCCGCAGCGGTACGGCTCAGCCCATTACCAGTTACGT
AACCATGATCACCGGTCCGGTGCCGGCCTGGCGGGGCGAAGGCGAGGGTATTAAGGAACTGCACGTCGTTCTTCTGGACA
ACGGGCGCACCAGGATGGCCGCCGACCCGGTCTTCAAGGAGGCCCTGCAGTGTATCCGCTGCGCCTCCTGCACCAACGTC
TGCCCGGTCTTCCAGCTGGTCAGCGGCCAGGTCTATGGTTATATTTACAACGGCGGTATCGGCAGTGTCCTCACGGCCTT
CTTCAATTCCCTGGAAGACGCCGTCGACCCCCAGAGCCTGTGTATCGGCTGCCGGCGCTGTGCCGAGGTCTGCCCGGCAA
AGATTAATATCCCCGATTTGGTGTTGAAGCTTCGGGAGCGGGTCGTCACGAAGCAGGGGCTTTCCAGCGGCTACCGGATC
GCCCTCCACGGCATAGTGGCTAAACCGAAGCTGATGCACACCCTCCTGCGGGCGGCCTCCCGCCTCCAGGGTCCGGTAAC
CCACGGCCAGCCCCTGATCCGGCACCTGCCTCTCTTCTTCAGCAACTTGACCTCCGGCCGCAGCCTGCCGGCCATTGCTA
AGGAGCCCCTGCGGGACCGGGTCAAACGCCTGGAGGCCCGTACCGGCAGGCCGCGTCTCAAGGCCGCCTTTTACAGCGGT
TGCGTAATTGACTTTGCCTACCCGGAGATCGGTGAGGCTGTTTATAAAGTGCTGGGGCGGGAAGGGGTGCAGGTAACATT
TCCCCAGGGCCAGGCCTGCTGCGGTGCCCCGGCAGTTTATGCCGGCGATCGGGAGACGGCGGTGAAGTTGGCCAAACAAA
ATATTACCGCGCTGGAAGAGGCCCGGGCCGATGTTGTGGTCACCGCCTGCCCTACCTGCGCCGTGGCCCTGAAAAAGGAC
TTTCCCGAGCTCCTGGCCGGCGAACCGGCCTGGGAGGAGCGGGCCAGGGCCCTGGCGAAGAAGGTAAAAGACTTTACCGA
GCTGGTCCATGAATTAACTGGCGGGCAGGGGAAAAAGGTCAAGCAGGCTAAAAAATCCGGCAGCGGGGCAGTAAAGGTTA
CCTATCATGACTCTTGTCATTTCAAGCGGCACCTGGGCCTGGACCAGGTGGCCAGGCAGGTTTTAAAGGAACAGCCGGGG
GTGGAACTGGTAGAGATGCAGGAAAGCGACCGCTGCTGCGGTTTTGGTGGTTCTTATAGCATCAAGTACCCGGAGATCAG
CGCCCCTATCCTGGAACGCAAGCTGAAAAATATTACCGAAAGTGGTGCGCAAGTGGTGGCTGCGGACTGCCCGGGCTGCG
TCCTGCAGCTACGCGGCGGCCTGGATCAGAAGGGCAGCTCTATCAAGGTCAAGCATACGGCTGAGGTGCTGGCGGCCTTG
GAGAACTTGCAGGGTGGCGGGAACAGTAAATAA

Upstream 100 bases:

>100_bases
CCCAGCCGCACGGCCGACATAGAACGCAGCCTGACCGTAGGTGTTCATGGGCCAGAGAGGCTGTTCATCATCCTGGTAGG
CGAAAACGGAGGTGCCAGCC

Downstream 100 bases:

>100_bases
CTCCCCGATTTTATTCCCGGAGGTGGGGACAGGTGGACCTGAGACCTATCAGGACTAAAAAAATCTACGAAGAGATCGTC
CAGCAGATTAAAGATCTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MAGKEFKQRIRQALNNASLRGALGRFADSYVVSREEVYAGRDFESLRQRIAAIKADAAGRYEELADRFSRAVEARGGKVF
RAKDAAAAREYIYQVAKEHGVTEIVKSKSFASEEIHLNEFLQERGINPYETDLAEWILQLMPGERPSHMVMPAIHLPKEE
VARVFSRYLGEPVEPDIKNMVRIARRELRKKFLTAGMGISGANIAVAETGTIVLCTNEGNARLTTTVPPVHVAIVGYEKL
VPSIKDIVPILEALPRSGTAQPITSYVTMITGPVPAWRGEGEGIKELHVVLLDNGRTRMAADPVFKEALQCIRCASCTNV
CPVFQLVSGQVYGYIYNGGIGSVLTAFFNSLEDAVDPQSLCIGCRRCAEVCPAKINIPDLVLKLRERVVTKQGLSSGYRI
ALHGIVAKPKLMHTLLRAASRLQGPVTHGQPLIRHLPLFFSNLTSGRSLPAIAKEPLRDRVKRLEARTGRPRLKAAFYSG
CVIDFAYPEIGEAVYKVLGREGVQVTFPQGQACCGAPAVYAGDRETAVKLAKQNITALEEARADVVVTACPTCAVALKKD
FPELLAGEPAWEERARALAKKVKDFTELVHELTGGQGKKVKQAKKSGSGAVKVTYHDSCHFKRHLGLDQVARQVLKEQPG
VELVEMQESDRCCGFGGSYSIKYPEISAPILERKLKNITESGAQVVAADCPGCVLQLRGGLDQKGSSIKVKHTAEVLAAL
ENLQGGGNSK

Sequences:

>Translated_730_residues
MAGKEFKQRIRQALNNASLRGALGRFADSYVVSREEVYAGRDFESLRQRIAAIKADAAGRYEELADRFSRAVEARGGKVF
RAKDAAAAREYIYQVAKEHGVTEIVKSKSFASEEIHLNEFLQERGINPYETDLAEWILQLMPGERPSHMVMPAIHLPKEE
VARVFSRYLGEPVEPDIKNMVRIARRELRKKFLTAGMGISGANIAVAETGTIVLCTNEGNARLTTTVPPVHVAIVGYEKL
VPSIKDIVPILEALPRSGTAQPITSYVTMITGPVPAWRGEGEGIKELHVVLLDNGRTRMAADPVFKEALQCIRCASCTNV
CPVFQLVSGQVYGYIYNGGIGSVLTAFFNSLEDAVDPQSLCIGCRRCAEVCPAKINIPDLVLKLRERVVTKQGLSSGYRI
ALHGIVAKPKLMHTLLRAASRLQGPVTHGQPLIRHLPLFFSNLTSGRSLPAIAKEPLRDRVKRLEARTGRPRLKAAFYSG
CVIDFAYPEIGEAVYKVLGREGVQVTFPQGQACCGAPAVYAGDRETAVKLAKQNITALEEARADVVVTACPTCAVALKKD
FPELLAGEPAWEERARALAKKVKDFTELVHELTGGQGKKVKQAKKSGSGAVKVTYHDSCHFKRHLGLDQVARQVLKEQPG
VELVEMQESDRCCGFGGSYSIKYPEISAPILERKLKNITESGAQVVAADCPGCVLQLRGGLDQKGSSIKVKHTAEVLAAL
ENLQGGGNSK
>Mature_729_residues
AGKEFKQRIRQALNNASLRGALGRFADSYVVSREEVYAGRDFESLRQRIAAIKADAAGRYEELADRFSRAVEARGGKVFR
AKDAAAAREYIYQVAKEHGVTEIVKSKSFASEEIHLNEFLQERGINPYETDLAEWILQLMPGERPSHMVMPAIHLPKEEV
ARVFSRYLGEPVEPDIKNMVRIARRELRKKFLTAGMGISGANIAVAETGTIVLCTNEGNARLTTTVPPVHVAIVGYEKLV
PSIKDIVPILEALPRSGTAQPITSYVTMITGPVPAWRGEGEGIKELHVVLLDNGRTRMAADPVFKEALQCIRCASCTNVC
PVFQLVSGQVYGYIYNGGIGSVLTAFFNSLEDAVDPQSLCIGCRRCAEVCPAKINIPDLVLKLRERVVTKQGLSSGYRIA
LHGIVAKPKLMHTLLRAASRLQGPVTHGQPLIRHLPLFFSNLTSGRSLPAIAKEPLRDRVKRLEARTGRPRLKAAFYSGC
VIDFAYPEIGEAVYKVLGREGVQVTFPQGQACCGAPAVYAGDRETAVKLAKQNITALEEARADVVVTACPTCAVALKKDF
PELLAGEPAWEERARALAKKVKDFTELVHELTGGQGKKVKQAKKSGSGAVKVTYHDSCHFKRHLGLDQVARQVLKEQPGV
ELVEMQESDRCCGFGGSYSIKYPEISAPILERKLKNITESGAQVVAADCPGCVLQLRGGLDQKGSSIKVKHTAEVLAALE
NLQGGGNSK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=474, Percent_Identity=34.3881856540084, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1788576, Length=420, Percent_Identity=26.4285714285714, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786497, Length=247, Percent_Identity=31.9838056680162, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI48994913, Length=428, Percent_Identity=22.4299065420561, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 79630; Mature: 79499

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKEFKQRIRQALNNASLRGALGRFADSYVVSREEVYAGRDFESLRQRIAAIKADAAGR
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
YEELADRFSRAVEARGGKVFRAKDAAAAREYIYQVAKEHGVTEIVKSKSFASEEIHLNEF
HHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
LQERGINPYETDLAEWILQLMPGERPSHMVMPAIHLPKEEVARVFSRYLGEPVEPDIKNM
HHHCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VRIARRELRKKFLTAGMGISGANIAVAETGTIVLCTNEGNARLTTTVPPVHVAIVGYEKL
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCEEEEECCCCEEEEEECHHHH
VPSIKDIVPILEALPRSGTAQPITSYVTMITGPVPAWRGEGEGIKELHVVLLDNGRTRMA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
ADPVFKEALQCIRCASCTNVCPVFQLVSGQVYGYIYNGGIGSVLTAFFNSLEDAVDPQSL
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHH
CIGCRRCAEVCPAKINIPDLVLKLRERVVTKQGLSSGYRIALHGIVAKPKLMHTLLRAAS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHH
RLQGPVTHGQPLIRHLPLFFSNLTSGRSLPAIAKEPLRDRVKRLEARTGRPRLKAAFYSG
HHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
CVIDFAYPEIGEAVYKVLGREGVQVTFPQGQACCGAPAVYAGDRETAVKLAKQNITALEE
CEEEECCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHH
ARADVVVTACPTCAVALKKDFPELLAGEPAWEERARALAKKVKDFTELVHELTGGQGKKV
CCCCEEEEECCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
KQAKKSGSGAVKVTYHDSCHFKRHLGLDQVARQVLKEQPGVELVEMQESDRCCGFGGSYS
HHHHHCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCE
IKYPEISAPILERKLKNITESGAQVVAADCPGCVLQLRGGLDQKGSSIKVKHTAEVLAAL
EECCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCEEEEHHHHHHHHHH
ENLQGGGNSK
HHHCCCCCCC
>Mature Secondary Structure 
AGKEFKQRIRQALNNASLRGALGRFADSYVVSREEVYAGRDFESLRQRIAAIKADAAGR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
YEELADRFSRAVEARGGKVFRAKDAAAAREYIYQVAKEHGVTEIVKSKSFASEEIHLNEF
HHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
LQERGINPYETDLAEWILQLMPGERPSHMVMPAIHLPKEEVARVFSRYLGEPVEPDIKNM
HHHCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VRIARRELRKKFLTAGMGISGANIAVAETGTIVLCTNEGNARLTTTVPPVHVAIVGYEKL
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCEEEEECCCCEEEEEECHHHH
VPSIKDIVPILEALPRSGTAQPITSYVTMITGPVPAWRGEGEGIKELHVVLLDNGRTRMA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
ADPVFKEALQCIRCASCTNVCPVFQLVSGQVYGYIYNGGIGSVLTAFFNSLEDAVDPQSL
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHH
CIGCRRCAEVCPAKINIPDLVLKLRERVVTKQGLSSGYRIALHGIVAKPKLMHTLLRAAS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHH
RLQGPVTHGQPLIRHLPLFFSNLTSGRSLPAIAKEPLRDRVKRLEARTGRPRLKAAFYSG
HHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
CVIDFAYPEIGEAVYKVLGREGVQVTFPQGQACCGAPAVYAGDRETAVKLAKQNITALEE
CEEEECCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHH
ARADVVVTACPTCAVALKKDFPELLAGEPAWEERARALAKKVKDFTELVHELTGGQGKKV
CCCCEEEEECCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
KQAKKSGSGAVKVTYHDSCHFKRHLGLDQVARQVLKEQPGVELVEMQESDRCCGFGGSYS
HHHHHCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCE
IKYPEISAPILERKLKNITESGAQVVAADCPGCVLQLRGGLDQKGSSIKVKHTAEVLAAL
EECCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCEEEEHHHHHHHHHH
ENLQGGGNSK
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA