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The map label for this gene is argC

Identifier: 83591111

GI number: 83591111

Start: 2402588

End: 2403628

Strand: Reverse

Name: argC

Synonym: Moth_2290

Alternate gene names: 83591111

Gene position: 2403628-2402588 (Counterclockwise)

Preceding gene: 83591112

Following gene: 83591110

Centisome position: 91.43

GC content: 60.52

Gene sequence:

>1041_bases
TTGATTAAAGCCGGAATTATCGGTGCTACCGGTTACACGGGAGCCGAACTGGTCCGCATTTTGAGCCGGCACCCGGAAGT
AGAGCTGGTAGCCCTTACCTCACGCAGTTACGCCGGGGAAGGGATGGCCGGCGTTTACCCGTCCCTTACCGGCTATACCA
ACCTCACCTGTGAGAATTTGACTCCCGATGAGGTTATGGACCGGGCGGAAGTTATCTTTATCGCCCTGCCCCACGGCCAC
GCCGTCCCGGTAGCCACCCGAGCCAGGGAACGGGGGATCAAAGTAATTGACCTGGGCGCCGACTGGCGCTTCCGTAACGC
CAGGACTTACGAAGAATGGTATAAAATCCAGCACGGCAACCACGAGCTGGCGGCCCGGGCCGTCTACGGGCTGCCGGAGA
TTCACCGGGAGGCCATCCGTAGCGCCGGCCTGGTGGCCAATCCCGGTTGTTACCCCACCAGCGCCATCCTGGGCCTGGCT
CCCCTGCTTAAGGGGGGGTACATTGACCCGGCGACCATCATAATCGACGCCAAGTCAGGGGTTTCCGGGGCCGGCCGGGA
GGCCAGGGTTACCAGCCTCTTTGTTGAGTGCAACGAAAGCATTAATCCCTACGGCGTCGCCAGTCACCGTCATACCCCGG
AGATCGAACAGGAACTCAGCGCCCTGGCCGGCAAAGAGGTTAAAGTAACCTTTACCCCCCACCTGCTTCCCATCAGCAGG
GGGATCTTGAGTACCATGTACGCCACCCTGGTACGGCCGGCATCGACGGAGGAACTGCGAAGGGTATATGAAAAATTTTA
TGCCGGTGAGCCCTTCGTCCACCTCCTACCCCCCGGCCAGTGGCCCCACACCCGCTGGGTATATGGCAGCAACAACTGCC
ACCTTAATCTCGCCGTAGATACCCGCACCGGCCGGGTGGTGGTGGCCAGCGCCATCGACAACCTGACCAAAGGCGCTTCC
GGCCAGGCGGTGCAGAACCTCAACCTTATGTGCGGTTTCCCGGAGACCATGGCCCTGGAAGTACCAGGATTGTGTCCATA
A

Upstream 100 bases:

>100_bases
GAGGTCAATGTTAAGATAAAGTAAAATTTTACCCAGCCTATTGCATTATTATACATCTAAAATGTATAATTATAAACACC
AACTGAGGAGGTCCCTTGCT

Downstream 100 bases:

>100_bases
ATACAGGAGACCAAGCACTCCACATTCCATACATGGAGGAGGAGACAATGACGCAAGACTTCCAGCCGGTTGCCGGCGGC
ATCACCGCCCCGCGGGGTTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENLTPDEVMDRAEVIFIALPHGH
AVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGNHELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLA
PLLKGGYIDPATIIIDAKSGVSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISR
GILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVDTRTGRVVVASAIDNLTKGAS
GQAVQNLNLMCGFPETMALEVPGLCP

Sequences:

>Translated_346_residues
MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENLTPDEVMDRAEVIFIALPHGH
AVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGNHELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLA
PLLKGGYIDPATIIIDAKSGVSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISR
GILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVDTRTGRVVVASAIDNLTKGAS
GQAVQNLNLMCGFPETMALEVPGLCP
>Mature_346_residues
MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENLTPDEVMDRAEVIFIALPHGH
AVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGNHELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLA
PLLKGGYIDPATIIIDAKSGVSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISR
GILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVDTRTGRVVVASAIDNLTKGAS
GQAVQNLNLMCGFPETMALEVPGLCP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=37.2093023255814, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320913, Length=338, Percent_Identity=31.9526627218935, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_MOOTA (Q2RG62)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431120.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q2RG62
- SMR:   Q2RG62
- STRING:   Q2RG62
- GeneID:   3831322
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2290
- NMPDR:   fig|264732.9.peg.2327
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   Q2RG62
- BioCyc:   MTHE264732:MOTH_2290-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37549; Mature: 37549

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 150-150

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENL
CCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
TPDEVMDRAEVIFIALPHGHAVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGN
CHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCEECCCCCHHHHHHHCCCC
HELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLAPLLKGGYIDPATIIIDAKSG
HHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
VSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISR
CCCCCCCCEEEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
GILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVD
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEEEEEE
TRTGRVVVASAIDNLTKGASGQAVQNLNLMCGFPETMALEVPGLCP
CCCCCEEEEEHHHHHHCCCCCCHHHCCEEEECCCCCEEEECCCCCC
>Mature Secondary Structure
MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENL
CCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
TPDEVMDRAEVIFIALPHGHAVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGN
CHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCEECCCCCHHHHHHHCCCC
HELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLAPLLKGGYIDPATIIIDAKSG
HHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
VSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISR
CCCCCCCCEEEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
GILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVD
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEEEEEE
TRTGRVVVASAIDNLTKGASGQAVQNLNLMCGFPETMALEVPGLCP
CCCCCEEEEEHHHHHHCCCCCCHHHCCEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA