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The map label for this gene is ttdA [C]

Identifier: 83591104

GI number: 83591104

Start: 2394498

End: 2395343

Strand: Reverse

Name: ttdA [C]

Synonym: Moth_2283

Alternate gene names: 83591104

Gene position: 2395343-2394498 (Counterclockwise)

Preceding gene: 83591105

Following gene: 83591103

Centisome position: 91.12

GC content: 62.29

Gene sequence:

>846_bases
GTGACCAGAATCATTACCTGCGACGAGATTACCAGGGCGGTGGCCGACCTCTGCCGGCAGGCCAATTACTACCTGGGGGA
GGACGTGCGGGGAGCCCTGGAAGGGGCCCTGGCCAGGGAGGTCTCGCCCCAGGGGAAAGACGTCCTTAATCAGCTCCTGG
AGAATGCCGCCATCGCCGCCGCCGAGGAGGTGCCCATCTGTCAGGATACGGGGGTGGCGGTGGTCTTCCTGGAACTGGGC
CAGGAGGTGCAGGTTCAAGGGGGCTATCTCTATGACGCCATCAATGCCGGCGTCCGCCAGGGGTATACTGAGGGCTACCT
GCGTAAATCCATGGTCTACCCGCCCCTGGACGGCCGGAATACGGGGGACAATACGCCGGCCATTATTCACACGGAAATTG
TTCCCGGTGATAAATTGACCATCACCGTGGCGCCCAAGGGCGGCGGTAGCGAAAATATGAGCGCCGCCGTCATGCTGGCG
CCGGCTGCCGGCATCCGGGGTGTTAAGGAGTTTGTCCTTGAGACCGTCAAGAAAGCCGGTCCCAATCCCTGCCCGCCGCT
GATCGTAGGGGTCGGCATCGGGGGTAATTTTGAAAAATGTGCCCTGCTGGCCAAAAAAGCCCTGCTACGCCCCCTGGGGG
AGCCCCATCCCCTGGAAGGGATAGCCACTCTGGAAAGGGATCTGCTGGAGAGCATCAACTGCCTGGGCATCGGTCCCGGG
GGTTTCGGAGGCCGGATGACGGCCCTGGCGGTGCACGTCGAGATCTTCGCCCGCCATATTGCCAGCCTGCCCGTAGCCGT
AAATATCCAGTGCCACGCCGCCCGGCATAAGAGCATCACCCTTTAG

Upstream 100 bases:

>100_bases
CGGCGGCCCGGCCCCGGAGGCCGTGGGGAAAGCCATAGAGCGGGCCAGGGAGATCCTTGCCGGGATTCAGGCTGGACTTT
CAAGATAGGGAGGGTAGCGG

Downstream 100 bases:

>100_bases
TAGGGGCAGCAAACCGTTCCACCATCGTTCCCGCGGGAATCTGCTCCTTGGAGACCACGGCGATGAAATAGTATTTACTT
TCTGGCCATATCATAAGGGG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTRIITCDEITRAVADLCRQANYYLGEDVRGALEGALAREVSPQGKDVLNQLLENAAIAAAEEVPICQDTGVAVVFLELG
QEVQVQGGYLYDAINAGVRQGYTEGYLRKSMVYPPLDGRNTGDNTPAIIHTEIVPGDKLTITVAPKGGGSENMSAAVMLA
PAAGIRGVKEFVLETVKKAGPNPCPPLIVGVGIGGNFEKCALLAKKALLRPLGEPHPLEGIATLERDLLESINCLGIGPG
GFGGRMTALAVHVEIFARHIASLPVAVNIQCHAARHKSITL

Sequences:

>Translated_281_residues
MTRIITCDEITRAVADLCRQANYYLGEDVRGALEGALAREVSPQGKDVLNQLLENAAIAAAEEVPICQDTGVAVVFLELG
QEVQVQGGYLYDAINAGVRQGYTEGYLRKSMVYPPLDGRNTGDNTPAIIHTEIVPGDKLTITVAPKGGGSENMSAAVMLA
PAAGIRGVKEFVLETVKKAGPNPCPPLIVGVGIGGNFEKCALLAKKALLRPLGEPHPLEGIATLERDLLESINCLGIGPG
GFGGRMTALAVHVEIFARHIASLPVAVNIQCHAARHKSITL
>Mature_280_residues
TRIITCDEITRAVADLCRQANYYLGEDVRGALEGALAREVSPQGKDVLNQLLENAAIAAAEEVPICQDTGVAVVFLELGQ
EVQVQGGYLYDAINAGVRQGYTEGYLRKSMVYPPLDGRNTGDNTPAIIHTEIVPGDKLTITVAPKGGGSENMSAAVMLAP
AAGIRGVKEFVLETVKKAGPNPCPPLIVGVGIGGNFEKCALLAKKALLRPLGEPHPLEGIATLERDLLESINCLGIGPGG
FGGRMTALAVHVEIFARHIASLPVAVNIQCHAARHKSITL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=275, Percent_Identity=33.0909090909091, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790564, Length=251, Percent_Identity=33.8645418326693, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787897, Length=249, Percent_Identity=34.5381526104418, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29607; Mature: 29475

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIITCDEITRAVADLCRQANYYLGEDVRGALEGALAREVSPQGKDVLNQLLENAAIAA
CCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AEEVPICQDTGVAVVFLELGQEVQVQGGYLYDAINAGVRQGYTEGYLRKSMVYPPLDGRN
HCCCCCCCCCCCEEEEEECCCEEEECCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
TGDNTPAIIHTEIVPGDKLTITVAPKGGGSENMSAAVMLAPAAGIRGVKEFVLETVKKAG
CCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
PNPCPPLIVGVGIGGNFEKCALLAKKALLRPLGEPHPLEGIATLERDLLESINCLGIGPG
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEECCC
GFGGRMTALAVHVEIFARHIASLPVAVNIQCHAARHKSITL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TRIITCDEITRAVADLCRQANYYLGEDVRGALEGALAREVSPQGKDVLNQLLENAAIAA
CEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AEEVPICQDTGVAVVFLELGQEVQVQGGYLYDAINAGVRQGYTEGYLRKSMVYPPLDGRN
HCCCCCCCCCCCEEEEEECCCEEEECCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
TGDNTPAIIHTEIVPGDKLTITVAPKGGGSENMSAAVMLAPAAGIRGVKEFVLETVKKAG
CCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
PNPCPPLIVGVGIGGNFEKCALLAKKALLRPLGEPHPLEGIATLERDLLESINCLGIGPG
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEECCC
GFGGRMTALAVHVEIFARHIASLPVAVNIQCHAARHKSITL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]