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The map label for this gene is lldR [H]

Identifier: 83591095

GI number: 83591095

Start: 2381792

End: 2382490

Strand: Reverse

Name: lldR [H]

Synonym: Moth_2274

Alternate gene names: 83591095

Gene position: 2382490-2381792 (Counterclockwise)

Preceding gene: 83591096

Following gene: 83591094

Centisome position: 90.63

GC content: 52.36

Gene sequence:

>699_bases
ATGGAATTCAAGCCCATTAAAACTAAAAAGATCTACGAAGAAATAGTCGAGCAGGTCAAAAAGTCCCTGAGCGAAGGGAA
GCTCATGCCCGGGGAGCGATTCTTCTCCGAAAGGGAATTGTCGGATAAACTTGGTGTCAGCCGGGCGTCTGTACGGGAGG
CCATCCGCGCTCTAACTACCATGGGTATCCTGGAAGTAAGGGCCGGGGAGGGGACCTTTGTCCGCCAGGTCCAGGACAGT
GACATTATCCAGCCCCTGGTTATGGCTTTGCTCCTGGAAGAACAGCAAGTCATATATCTGCTGGAAGCCAGGCAGATCCT
TGAACGGGAAATAGTTTACCTGGCGGCGCAGCGGGCGACCACCGAGGAAAAGGAAAAACTGGTGGGTATACTCCAGCATA
TGGCCGATGAACTCGCCCGTGGCTTTCTCCAGGAGGATACTGACGTCCGCTTTCACTTGACCATTGCCGGAATGACCCAT
AATCCCATTGTCTCACGCCTGATGTATACCATTGCCGATACCATTGCCCAGACCCTGGCCACTAAACGTCAACAGTTATA
CTCCAACCTGGAAAATGCAAGGTTGCTTTATGAACAGCATAGCGAGATTACCCAGGCCATTATCTCCGGGGCTGCCGATA
GCGCTCGCAAGGCAATGGCCAAGCACTTGCGTTTTGTCGCCCAGAAGTTGAAGAAGTGA

Upstream 100 bases:

>100_bases
GCCGGAGGAATAGCAACTTTTCCATGTCAAGGTAGTGTCAAGGTAATTGCTATCGCCTTAAAAATGTGATAATAATCAAA
AACAACTTGAGGTAATGTCG

Downstream 100 bases:

>100_bases
CCCCTATGTAGCTAATGCCTGAGCCTTCATTGCTCGCGCAGCGAGGTACGAAGGAGGGATGAAAGGCGGGCTTAAATTTT
TCGAGGGAATCTTAAGGTGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEFKPIKTKKIYEEIVEQVKKSLSEGKLMPGERFFSERELSDKLGVSRASVREAIRALTTMGILEVRAGEGTFVRQVQDS
DIIQPLVMALLLEEQQVIYLLEARQILEREIVYLAAQRATTEEKEKLVGILQHMADELARGFLQEDTDVRFHLTIAGMTH
NPIVSRLMYTIADTIAQTLATKRQQLYSNLENARLLYEQHSEITQAIISGAADSARKAMAKHLRFVAQKLKK

Sequences:

>Translated_232_residues
MEFKPIKTKKIYEEIVEQVKKSLSEGKLMPGERFFSERELSDKLGVSRASVREAIRALTTMGILEVRAGEGTFVRQVQDS
DIIQPLVMALLLEEQQVIYLLEARQILEREIVYLAAQRATTEEKEKLVGILQHMADELARGFLQEDTDVRFHLTIAGMTH
NPIVSRLMYTIADTIAQTLATKRQQLYSNLENARLLYEQHSEITQAIISGAADSARKAMAKHLRFVAQKLKK
>Mature_232_residues
MEFKPIKTKKIYEEIVEQVKKSLSEGKLMPGERFFSERELSDKLGVSRASVREAIRALTTMGILEVRAGEGTFVRQVQDS
DIIQPLVMALLLEEQQVIYLLEARQILEREIVYLAAQRATTEEKEKLVGILQHMADELARGFLQEDTDVRFHLTIAGMTH
NPIVSRLMYTIADTIAQTLATKRQQLYSNLENARLLYEQHSEITQAIISGAADSARKAMAKHLRFVAQKLKK

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=228, Percent_Identity=34.6491228070175, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786303, Length=234, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790780, Length=238, Percent_Identity=32.3529411764706, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=27.3542600896861, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789621, Length=228, Percent_Identity=29.8245614035088, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789353, Length=238, Percent_Identity=24.3697478991597, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994961, Length=217, Percent_Identity=29.9539170506912, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994955, Length=166, Percent_Identity=27.710843373494, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26415; Mature: 26415

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKPIKTKKIYEEIVEQVKKSLSEGKLMPGERFFSERELSDKLGVSRASVREAIRALTT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MGILEVRAGEGTFVRQVQDSDIIQPLVMALLLEEQQVIYLLEARQILEREIVYLAAQRAT
HHHHHEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TEEKEKLVGILQHMADELARGFLQEDTDVRFHLTIAGMTHNPIVSRLMYTIADTIAQTLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
TKRQQLYSNLENARLLYEQHSEITQAIISGAADSARKAMAKHLRFVAQKLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFKPIKTKKIYEEIVEQVKKSLSEGKLMPGERFFSERELSDKLGVSRASVREAIRALTT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MGILEVRAGEGTFVRQVQDSDIIQPLVMALLLEEQQVIYLLEARQILEREIVYLAAQRAT
HHHHHEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TEEKEKLVGILQHMADELARGFLQEDTDVRFHLTIAGMTHNPIVSRLMYTIADTIAQTLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
TKRQQLYSNLENARLLYEQHSEITQAIISGAADSARKAMAKHLRFVAQKLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]