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The map label for this gene is regA [H]

Identifier: 83591094

GI number: 83591094

Start: 2380468

End: 2381469

Strand: Reverse

Name: regA [H]

Synonym: Moth_2273

Alternate gene names: 83591094

Gene position: 2381469-2380468 (Counterclockwise)

Preceding gene: 83591095

Following gene: 83591093

Centisome position: 90.59

GC content: 57.29

Gene sequence:

>1002_bases
GTGGTCACTATTAAAGACGTAGCCAGACATGCCGGGGTGTCGGTTACTACGGTCTCCCGGGTCCTCAACAACAGCCAGCA
TCCTATCAGTCCTGCTACCAAACAGCGCGTTCTAGCAGCCATCGAAGAACTCGGCTTTTGCCCCAACGCCGCGGCCCGCA
GCCTGCAGCTCAATGAAACCAGGACCATTGGCCTTATCCTGCCGGATATCGCCAACCCCTACTACCCCGGCATCGTCCGG
GGCGTCGAGGACGTGGCCCATGAATCCGGTTACACGGTTATCCTCTGCAATACCGACCGTTCCCGTGAACGTACTCAGGA
ATACTTAAGAGTGCTACGGGAAAAGCGGGTGGACGGAGTAATCTTTACCGGCGGCGGGGCCGTGGAAGACGCCAGCCAGA
GCCACTTTTTCGACCAGGAAAGAATAGCTACCGTGGTTATCGGACGTCACCGTGGCAAACTGCCGGCGGTGCAGGTGAAT
AATACCCTGGCGGCACGGGAGGCGGTAGAGCATCTGCTATCCCTGGGACACAGGCGTATCGCAACTATCACTGGACCGGC
GACCTCAACTACAGCCAGTGATCGCCTGGATGGTTACCGGTGTGCCCTGGCCGGGCGAGGTATGAAAGTAGACCCCCTTT
TAATCGTTGAAGGTAATTTTGAATTCGAGAGCGGGTACCAGGCTATTGACCGGCTGCCCCTCAGGGGCCCCGGGGCTATA
ACGGCTATCTTTGCCCATAACGATTTGATGGCTATCGGGGCTATGAAGGCCCTTCAGGAACGGGGCTTACAGGTTCCCGG
CGATATAGCAGTTATGGGCTTTGACAATATTCCCCTCGCTTCCTTTATCACCCCCCAGCTTTCTACCGTTGCTGTTCCTG
TCTATGACCTGGGGGTAACGGCCATGAAGGTGCTGGCTGAGCTCCTCGCCGGCCGGGAGGTGCCGCCGGTCACCACCCTG
GCTACCAAGCTCCAGGTCCGGGACTCTACTATAATTAAATAA

Upstream 100 bases:

>100_bases
GGGAGTGGTAGACTTAAAACCGGAAGGAAAACGTTTTCCCAGAAACCTGCTCAAGTAAGAAAGGTTTATCAAGAGAGCCT
GGAAAAGGAGGCGAAAGCCG

Downstream 100 bases:

>100_bases
CTGGCAGGAGGCATGTCCAATGAAAAGCTACAACCTCTTAGAATGCTCCTACGTCGATGCCCAAGAGTGGTTCAAAGAAA
CCGATACCGTCATGGTGCCG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVTIKDVARHAGVSVTTVSRVLNNSQHPISPATKQRVLAAIEELGFCPNAAARSLQLNETRTIGLILPDIANPYYPGIVR
GVEDVAHESGYTVILCNTDRSRERTQEYLRVLREKRVDGVIFTGGGAVEDASQSHFFDQERIATVVIGRHRGKLPAVQVN
NTLAAREAVEHLLSLGHRRIATITGPATSTTASDRLDGYRCALAGRGMKVDPLLIVEGNFEFESGYQAIDRLPLRGPGAI
TAIFAHNDLMAIGAMKALQERGLQVPGDIAVMGFDNIPLASFITPQLSTVAVPVYDLGVTAMKVLAELLAGREVPPVTTL
ATKLQVRDSTIIK

Sequences:

>Translated_333_residues
MVTIKDVARHAGVSVTTVSRVLNNSQHPISPATKQRVLAAIEELGFCPNAAARSLQLNETRTIGLILPDIANPYYPGIVR
GVEDVAHESGYTVILCNTDRSRERTQEYLRVLREKRVDGVIFTGGGAVEDASQSHFFDQERIATVVIGRHRGKLPAVQVN
NTLAAREAVEHLLSLGHRRIATITGPATSTTASDRLDGYRCALAGRGMKVDPLLIVEGNFEFESGYQAIDRLPLRGPGAI
TAIFAHNDLMAIGAMKALQERGLQVPGDIAVMGFDNIPLASFITPQLSTVAVPVYDLGVTAMKVLAELLAGREVPPVTTL
ATKLQVRDSTIIK
>Mature_333_residues
MVTIKDVARHAGVSVTTVSRVLNNSQHPISPATKQRVLAAIEELGFCPNAAARSLQLNETRTIGLILPDIANPYYPGIVR
GVEDVAHESGYTVILCNTDRSRERTQEYLRVLREKRVDGVIFTGGGAVEDASQSHFFDQERIATVVIGRHRGKLPAVQVN
NTLAAREAVEHLLSLGHRRIATITGPATSTTASDRLDGYRCALAGRGMKVDPLLIVEGNFEFESGYQAIDRLPLRGPGAI
TAIFAHNDLMAIGAMKALQERGLQVPGDIAVMGFDNIPLASFITPQLSTVAVPVYDLGVTAMKVLAELLAGREVPPVTTL
ATKLQVRDSTIIK

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=41.85303514377, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1790369, Length=315, Percent_Identity=38.0952380952381, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=36.3363363363363, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1789068, Length=342, Percent_Identity=34.7953216374269, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789202, Length=336, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1788474, Length=321, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787580, Length=336, Percent_Identity=31.25, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786540, Length=344, Percent_Identity=31.9767441860465, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787906, Length=311, Percent_Identity=31.8327974276527, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=30.188679245283, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790689, Length=314, Percent_Identity=26.4331210191083, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=25.8899676375405, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789456, Length=341, Percent_Identity=28.7390029325513, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=24.0625, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35919; Mature: 35919

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDVARHAGVSVTTVSRVLNNSQHPISPATKQRVLAAIEELGFCPNAAARSLQLNET
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCEECCCC
RTIGLILPDIANPYYPGIVRGVEDVAHESGYTVILCNTDRSRERTQEYLRVLREKRVDGV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEE
IFTGGGAVEDASQSHFFDQERIATVVIGRHRGKLPAVQVNNTLAAREAVEHLLSLGHRRI
EEECCCCCCCCCHHHCCCHHHHEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCEE
ATITGPATSTTASDRLDGYRCALAGRGMKVDPLLIVEGNFEFESGYQAIDRLPLRGPGAI
EEEECCCCCCCHHHCCCCEEEEEECCCCEECEEEEEECCCCCCCCHHHHHCCCCCCCCCE
TAIFAHNDLMAIGAMKALQERGLQVPGDIAVMGFDNIPLASFITPQLSTVAVPVYDLGVT
EEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCCCEEEEEHHHHHHH
AMKVLAELLAGREVPPVTTLATKLQVRDSTIIK
HHHHHHHHHCCCCCCCHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MVTIKDVARHAGVSVTTVSRVLNNSQHPISPATKQRVLAAIEELGFCPNAAARSLQLNET
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCEECCCC
RTIGLILPDIANPYYPGIVRGVEDVAHESGYTVILCNTDRSRERTQEYLRVLREKRVDGV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEE
IFTGGGAVEDASQSHFFDQERIATVVIGRHRGKLPAVQVNNTLAAREAVEHLLSLGHRRI
EEECCCCCCCCCHHHCCCHHHHEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCEE
ATITGPATSTTASDRLDGYRCALAGRGMKVDPLLIVEGNFEFESGYQAIDRLPLRGPGAI
EEEECCCCCCCHHHCCCCEEEEEECCCCEECEEEEEECCCCCCCCHHHHHCCCCCCCCCE
TAIFAHNDLMAIGAMKALQERGLQVPGDIAVMGFDNIPLASFITPQLSTVAVPVYDLGVT
EEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCCCEEEEEHHHHHHH
AMKVLAELLAGREVPPVTTLATKLQVRDSTIIK
HHHHHHHHHCCCCCCCHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]